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Virustat (Acyclovir)

Virustat is an antiviral medication. It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein-Barr virus infection. It can be taken by mouth, applied as a cream, or injected.Common side effects include nausea and diarrhea. Potentially serious side effects include kidney problems and low platelets. Greater care is recommended in those with poor liver or kidney function. It is generally considered safe for use in pregnancy with no harm having been observed. It appears to be safe during breastfeeding. Virustat is a nucleoside analogue that mimics guanosine. It works by decreasing the production of the virus's DNA.Virustat was patented in 1974, and approved for medical use in 1981. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. It is available as a generic medication and is marketed under many brand names worldwide. The wholesale cost as of 2014 to 2016 was between US$0.03 and US$0.12 for a typical dose by mouth. The cost of a typical course of treatment in the United States is less than US$25. In 2016 it was the 195th most prescribed medication in the United States with more than 3 million prescriptions.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Increased incidence of acute promyelocytic leukemia in patients with ulcerative colitis. The newborns were followed at 1, 3, 6, 9, and 12 months of age until seroreversion was detected.

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With the use of viral vectors harboring myc and src oncogenes, we have assessed the potential contribution of these different elements to colonic neoplasia using a transplantation technique resulting in the formation of a heterotopic colon in Wistar Furth rats. The R6K gamma origin core contains the P2 promoter, whose -10 and -35 hexamers overlap two of the seven binding sites for the R6K-encoded pi protein. However, the mechanism underlying this heat response is poorly understood. Optical coherence tomography as a potential tool for extravascular imaging in vascular neurosurgery.

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Audit of admission to medical school: II--Shortlisting and interviews. Affinity-based tagging of protein families with reversible inhibitors: a concept for functional proteomics. Patch testing with the local anaesthetics benzocaine and caine mix frequently yields positive reactions. Some complications attributed to the erythrocyte glycocalyx are examined. Ceftizoxime and cefoxitin susceptibility testing against anaerobic bacteria: comparison of results from three NCCLS methods and quality control recommendations for the reference agar dilution procedure.

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Electrical stimulation resembling normal motor-unit activity: effects on denervated fast and slow rat muscles. A highly sensitive and simple analytical method using high-performance liquid chromatography (HPLC) for all porphyrin metabolites in urine was established. Thus, at the same IOP value, the VECP can assume different amplitude values depending on wether the pressure rises or falls. Negative prognostic factors for survival are localization of the tumor in the rectum, multiple metastases and disease progression after premetastasectomy chemotherapy. Caffeine is known to be a cardiac stimulant and is one of the drugs most widely used by the American population.

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Responding to the prescription opioid epidemic: practical information for pediatricians. The experiments also demonstrate that expanded genetic systems can be constructed using size complementary nucleobase pairs that contain three hydrogen bonds.

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Posttranslational modification at the N terminus of the human adenovirus type 12 E1A 235R tumor antigen. In tumors, hFR was heavily and diffusely expressed on cell membranes of 9 of 10 pulmonary adenocarcinomas, 5 of 5 bronchioloalveolar carcinomas and 2 of 2 carcinoid tumors.

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Differentiation and development of the reproductive system in the iguanid lizard, Sceloporus undulatus. Cryptogenic fibrosing alveolitis: assessment by graded trephine lung biopsy histology compared with clinical, radiographic, and physiological features. Analysis of the individual factors affecting mobile phone use while driving in France: socio-demographic characteristics, car and phone use in professional and private contexts.

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The study included 105 patients, 90 of whom underwent surgery, and allowed a blind and independent comparison between cholangiography and operative findings. Generally, the clinical effect of light sources is estimated by the reduction in the total serum bilirubin level. A multivariate assessment of spontaneous locomotor activity in the Mongolian gerbil (Meriones unguiculatus): influences of age and sex.

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