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The results shown here suggest that these functional interactions may have biological relevance and that the interplay of different DNA binding proteins might modulate reverse gyrase activity in DNA metabolic pathways. Monoclonal antibodies to human T lymphocyte subsets and HLA-DR antigens were used to characterize the intra-epithelial T lymphocytes and HLA-DR reactive cells in the duodenal epithelium in dermatitis herpetiformis (DH). The ninth documented case of leiomyomatosis peritonealis disseminata (LPD) combined with pregnancy is presented. The antitumour activity of the lipopeptide in MCF-7 cells was associated with cell apoptosis determined by typical morphological changes and sub-G(1) peak in cell growth-phase distribution. Moreover, the FOR output signal appears to change systematically depending on the actual kinematic properties of the saccade, in a way that would help to maintain saccadic accuracy.

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A whole blood sample from living patients was requested for DNA extraction followed by a search for mutations of the genes ABCC8, KCNJ11, GCK, GLUD1, HADH, SLC16A1 and HNF4A. The MICs and minimal bactericidal concentrations of sodium nitrite-ascorbic acid in acidic urine were comparable to those of conventional antibiotics. The directional characteristics of the peripheral auditory system were assessed from studying the effects of sound direction on the responses of single auditory fibers in the eighth nerve of leopard frogs (Rana pipiens). The differences in chlorideion levels in sweat secretion tests and mean IRT values were statistically significant and were: 97.5 for the control group and 26.4 for the test group.

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Blood was sampled after induction of anesthesia, at skin closure, 2 hours, 24 hours, and 48 hours postoperatively. To clarify the mechanism by which metformin regulates fatty acid metabolism, a cDNA microarray and quantitative real-time PCR were used to examine the effects of metformin on the transcriptome of C2C12 cells treated with 200 micromol/L oleic acid.

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Age differences in intercorrelations between regional cerebral metabolic rates for glucose. Highly efficient enzymatic synthesis of tert-butyl (S)-6-chloro-5-hydroxy-3-oxohexanoate with a mutant alcohol dehydrogenase of Lactobacillus kefir.

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In contrast to endothelia, in which ASA simultaneously induces HO-1 mRNA and protein expression, gastric epithelial cells require vitamin C to translate HO-1 mRNA into active protein, which then may exert gastroprotection by its antioxidant and vasodilative properties. The body shapes of humans and chimpanzees were compared quantitatively by criteria chosen for their capacity to discriminate well among the body shapes of frogs. Phagocytic capacity and NADH-dependent oxidase activity of PMNL proved to be normal. Synergistic protective effects with azelastine and salbutamol in a guinea pig asthma model.

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The protein content of many spices was comparable to that of whole grains and mature dry legumes. Application of in vitro soft agar techniques for growth of tumor cells to the study of colon cancer. Effect and mechanism of Vav3 on the proliferation of human gastric cancer SGC7901 cells

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Norms of the Attitudes Toward Intellectual Disability Questionnaire. In asynchronously growing HeLa cells, we have determined that serine 216 is the major site of Cdc25C phosphorylation.

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Although it is understood that a looped wire technique using a 0.035-inch wire for femoropopliteal (FP) long chronic total occlusions (CTOs) goes to the subintima, there has been no systematic assessment of wire passages. The measurement error is initially guessed, and the Optimal Segments technique is used to filter a corresponding amount of variation from the data, thus generating a relatively smooth curve.

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A strong inflammatory response to community-acquired pneumonia (CAP) is associated with excess morbidity and mortality. Blood samples were collected up to 48 hours post-infusion for analysis. Using a modified RAND technique we developed in three rounds new QIs for blood use at Dutch intensive care units (ICUs). Comparative studies of porphyrin production in Propionibacterium acnes and Propionibacterium granulosum. Because leukocyte activation is obligatory for atherogenesis, leukocyte activation by triglyceride-rich lipoproteins (TRLs) was investigated.

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Our findings also suggest that psychological stress and control beliefs may provide one explanation for links between SES and immune responses in childhood asthma. A different type of exact inference is developed under Type II censoring. Functions of accessory cells in B cell responses to thymus-independent antigens. Moreover, in two out of eight lines, the Thy-1.2 allele was also expressed. Using sympathetic neuronal cultures, we analyzed the effect of adenoviral infection on viral and neuronal gene expression and on neuronal function and viability.

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Spectral density between 0.003 to 1.0 Hz increased with gestational age with large changes, in particular, at lower frequencies. Magnetic resonance imaging showed a large posterior spinal epidural hematoma, with compression and anterior dislocation of the spinal cord.

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Detection of Salmonellae in food by an immunofluorescence technic Three patients with sonographically demonstrated portal venous gas are presented. This brief report summarizes a survey of high school and college representatives and their awareness toward gambling-related problems. Radioactive seed implantation and lobaplatin chemotherapy are safe and effective in treating patients with advanced lung cancer. We considered as disaster each event producing casualties and requiring intervention of the civil protection services during the period 1982-1993, excluding minor transit accidents with no participation of the civil protection services.

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To investigate the role of specific sequence differences in these Env proteins, we constructed SIV mutants encoding 1A11 or 239 Env proteins with reciprocal exchanges of the CT or exchanges of both the surface unit (SU) and CT sequences. We describe the computed tomographic findings correlated with the radionuclide imaging and surgical findings and review the related literature. Our results indicate that vitrectomy is a useful procedure in the management of certain cases of uncomplicated rhegmatogenous retinal detachment. Evidence of gonorrheal infection was based on a positive gonorrhea culture.

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A bedside ultrasound scan allows for rapid evaluation in time-sensitive critically ill patients and can promote prompt treatment without the need to delay for further imaging studies. The usefulness of multiparameter studies in subclassifying T-cell malignancies is discussed and the literature on T-prolymphocytic leukemia reviewed. We have examined the effects of enucleation and of inhibitors of mRNA synthesis (actinomycin D and cordycepin) on protein turnover of HeLa cells.

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The safety and efficacy of the NS3/4A protease inhibitor faldaprevir in combination with the non-nucleoside NS5B polymerase inhibitor deleobuvir and ribavirin in Japanese treatment-naive patients with chronic genotype 1 hepatitis C virus (HCV) infection was evaluated. This is higher than the levels for damage reported for noncoherent ultraviolet sources. The final phase of immunosuppression will be the induction of antigen-specific depression of allograft reactivity.

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Validation of histomolecular classification utilizing histological subtype, MUC1, and CDX2 for prognostication of resected ampullary adenocarcinoma. There were a few neural connections between anterior and posterior SC, or horizontal and posterior SC, indicating receptor-receptor fibers. We believe this to be the only known case of this congenital anomaly associated with body segmental renal dysplasia and aganglionic megacolon.

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Effects of exogenous sodium and potassium on tonus and drug-induced contractions of the pulmonary artery strip of the rabbits with special reference to their relationship to calcium It has been applied, by extending the concept of the three-step mechanism for protein folding proposed in our previous paper, to simulate the folding of bovine pancreatic trypsin inhibitor, using a Monte Carlo procedure in all three steps, A, B, and C.

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Conformationally constrained pregnanes: structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one. The replacement of some of the soybean meal by the first limiting amino acids in practical broiler diets. Due to basic differences between the conservative and surgical approaches to the treatment of chronic venous leg ulcer, there are still a large variety of different therapeutic strategies applied today. To determine whether these two forms of IgA represent allotypic or isotypic variants, we purified serum IgA and prepared IgA-secreting somatic cell hybrids from mitogen-stimulated BALB/c and NZB mice and determined the pattern of light chain linkage. sigma-ADH is strongly inhibited by 4-methylpyrazole, but with a Ki (10 microM) still higher than that for a class I isoenzyme.

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All of these results demonstrate the promise of integrating PCR and electrophoresis on microchip for developing easy-carrying instruments for the fast in situ detection of DNA. The covalently closed circular form has a sedimentation coefficient of 22S. Both responses were blocked by the serotonin antagonist methysergide. Lack of antibodies to glutamic acid decarboxylase in young adults of the high diabetes prevalence Wanigela people of Papua New Guinea.

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Most of the allergens can be identified by sequence homologies and the structures of the major allergens have been solved. Here, we show a novel approach to preventing angiogenesis-targeting splicing factor kinases that are highly expressed in melanomas. The results clearly define a stoichiometry of one heme d per complex. Gas chromatographic determination of dimethyl acetamide in water In the control group there was one case of deep vein thrombophlibitis, seven cases of pulmonary emboli, and three deaths directly attributable to pulmonary emboli.

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Sensory impairments and mortality in an elderly community population: a six-year follow-up study. Non-viral cellular substrates for human immunodeficiency virus type 1 protease. The present paper describes some of the most important factors and tries on basis of the present literature to evaluate the evidence of these factors.

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We discuss the basic principles of these emerging technologies and their current and potential applications in early cancer detection. Efficacy and time course of paired associative stimulation in cortical plasticity: Implications for neuropsychiatry. There was a significant dose dependent reduction of total sodium efflux rate constant due to a reduction in ouabain sensitive sodium pump activity, glycoside insensitive efflux rate constants being unaffected. Timely delisting of patients who are-temporarily-too well for transplantation is the best waiting list policy.

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We compare here the ability of independently purified GCDFP-15, SABP and gp17 and of recombinant PIP both to cross-react with a panel of monoclonal antibodies (MAbs) raised against GCDFP-15 or gp17, respectively, and to bind to CD4. The formula used is restricted to cases in which the concentration of receptor is negligible compared to the concentration of both the displacing ligand and the radioactive ligand used. Effects of time on volume and distribution of coronary collateral flow. Coral bleaching is the consequence of disruption of the mutualistic Cnidaria-dinoflagellate association.

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Underestimation of Na permeability in muscle cells: implications for the theory of cell potential and for energy requirement of the Na pump. A study of the effects of an inclusion model on students with specific learning disabilities. Previous studies have demonstrated that this response is antibody dependent and antigen specific (Kaattari and Irwin, 1985).

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This finding suggests the child was infected with a variant virus that was not neutralized by antibodies resulting from HB vaccination. At the end of three hours of hemoperfusion, her theophylline level had fallen to 14.4 microgram/ml and four hours later it was 8.8 microgram/ml.

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False aneurysms alone were seen in 23 patients, arteriovenous fistulae in another 35, and both lesions concurrently in 6 patients. (11), who used a selective silver impregnation method in cat brains.

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Improved lung tumor visualization by computerized subtraction scintigraphy using 67Ga citrate and 113mIn chloride We attempted to determine the proportion of patients with a diagnosis of alcoholism who were prescribed naltrexone in the Department of Veterans Affairs health-care system during a 6-month period and the sociodemographic and clinical characteristics that distinguished them from veterans who were not prescribed naltrexone. We explore the role for a theory-based framework and suggest some of the methods that would be needed to operationalize the framework in the context of designing and conducting interventions aimed at improving the use of research findings by individual healthcare professionals or teams.

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These findings suggest that, in addition to the known clinicohematological effects, IFN-alpha can improve both the T and natural killer compartments in patients with HCL. However, alpha2-adrenoceptor regulation of NE release was unaffected by diabetes and hormone treatment.

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Patient samples were assayed and results compared to a standard fluoroimmunometric C1q-binding immune complex assay. In contrast to LPS responder mice, both BRD509 and GIDIL2 strains persisted at higher levels in LPS non-responder animals.

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Around the 45-0 mm stick incorrect assessments were distributed evenly between dimensions higher or lower than the reference stick. The origin of the hypoglycemic phase does not seem to be pancreatic, but may be hepatic. This study sought to investigate the afferent connections of the thalamus in the rat following massive telencephalic lesions. Functional activity of neutrophils from bovine mammary glands infected with Staphylococcus aureus. Evoked potentials in inherited ataxias: a multimodal electrophysiological study.

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Monolayers of activated HUVECs stained with fluorescent anti-ICAM-1 Fabs or Chinese hamster ovary-K1 cells expressing ICAM-1-green fluorescent protein were allowed to bind LFA-1-bearing monocytes, neutrophils, or K562 LFA-1 transfectants. Side-effects here are doubled when the patients serum albumin is below 2.5g/100ml(lewis et al.1971). During pulmonary vein isolation (PVI), a circular lasso catheter is positioned at the junction between the left atrium (LA) and the pulmonary vein (PV) to confirm PVI. Effect of ischemia on the activity of DNA-dependent RNA polymerase and DNA polymerase. Repeated measurement of hypoxic ventilatory response as an intermittent hypoxic stimulus.

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Thus, IL-T is a lymphokine that plays a role in T-cell proliferation and induction of lymphokine-activated killer cells. and Chironomus plumosus are negative except in the last case, but only with doses much higher than those which are lethal for mosquito larvae.

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Tube migration was enhanced during pregnancy compared with baseline values, but the values were significantly lower in the pre-eclamptic group. IL-1 concentrations in all culture media were readily detected but showed no differences between different tissues or between PCO and normal ovaries.

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Age did not influence the effectiveness of radiation therapy for the elderly patients. The aim of the present study was to determine the effects of early and late onset of menarche on menstrual disturbances and anthropometric measures among university students. Combination therapy with allopurinol and probenecid is used to treat tophaceous gout in patients who do not respond sufficiently to allopurinol alone.

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Serial sections of the atrioventricular conduction system revealed diffuse and severe acute inflammatory changes in the right bundle and the left bundle branches, especially in the terminal portions. Standard methods of congestive heart failure therapy were used in each patient, including bed rest, restriction of sodium, and drug therapy including digoxin. Leak point pressures (LPP) can be classified as detrusor or abdominal. These features are due to intrahepatic invasion of the bile duct and by providing a diagnosis preoperatively can have a large bearing on the choice of therapy for a particular patient.

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The size of the resulting individual restriction fragments was determined by relative fluorescence intensity and apparent molecular contour length. Both the left internal mammary graft to the left anterior descending artery and the right gastroepiploic artery to the right coronary artery were used as an in situ graft.