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The data demonstrate that CSA elaboration was maximal 24 h post-VLB, corresponding to the nadir of bone marrow GM-CFC, and 6 h after splenic reached a minimum. A micrometastasis was found in only 1 case (1 node) on the original histologic section, which was 1 of the 2 cases not originally processed by multiple-level sectioning.

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Fourteen of 24 patients with a severe or complicated urinary tract infection were cured by treatment with a 4-14 day course of sisomicin. All subjects participated in a prospective study with functional magnetic resonance imaging (fMRI) at baseline and after 12 weeks.

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Thrombin directly induces a variety of cellular responses through its specific receptors known as protease-activated receptors (PARs). The enzyme-modification/mass spectrometric approach has a definite use in a number of applications, including: the verification/identification of protein sequence, elucidation of post-translational modifications, the investigation of protein higher-order structure, and even the characterization of the modifying enzyme. Cross-sectional analysis of data from the ReCEnT (Registrars Clinical Encounters in Training) cohort study. In general, the dendritic field was in the form of an ellipse with mean major and minor axes of 0.22 mm and 0.11 mm respectively, and encompassing an area of about 0.13 mm2. Depot LA produced marked sustained hypoestrogenemia and significant bone loss with incomplete recovery 1 year after stopping treatment.

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The pain was evaluated using the Visual Analog Scale (VAS) before and after 3 months. Flow-mediated (endothelium-dependent) and nitrate induced (endothelium-independent) dilatation of the brachial artery was evaluated in all groups.

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The increase in plasma IL-6 in response to adrenaline given by subcutaneous (SC) route and by IV infusion could be blocked by the beta-adrenergic receptor antagonist l-propranolol but not by d-propranolol. Further insight into the impact of sodium selenite on selenoenzymes: high-dose selenite enhances hepatic thioredoxin reductase 1 activity as a consequence of liver injury.

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Activation of E2F-mediated transcription by human T-cell leukemia virus type I Tax protein in a p16(INK4A)-negative T-cell line. ZP120 causes relaxation by pre-junctional inhibition of noradrenergic neurotransmission in rat mesenteric resistance arteries. Twenty-six patients were followed up for 2 years after a first intravesical BTX-A injection. Determination of chlortetracycline in swine plasma by LC-ESI/MS/MS. Acceptance and effects of fluoride gel treatment among school-children

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Subsequent investigations revealed chylous ascites, pericardial constriction and bilateral chylothorax. In this review the in vitro and in vivo findings with various capsid deletion mutants of TBEV are summarized and discussed in the context of recent structural and biochemical data obtained for protein C of various flaviviruses. The addition of IL 1 or IL 2 to Pan T2-stimulated non-responder lymphocytes did not activate T cell proliferation, while the addition of responder monocytes restored the proliferation capacity in non-responder PBMC. Protein-lipid-lipopolysaccharide association in the superficial layer of Spirillum serpens cell walls. The removal of cholesterol from cells, like its delivery, appears to be specific and well regulated.

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The conclusions are: (1) elevation of ANF levels at increasing pacing rate is mainly due to atrial distension rather than atrial pressure per se. When an item is excised from the context, the perception of the intended category depends heavily on the communicative importance it had in the discourse. Both angiotensin II antagonists induced a significant increase in urinary sodium excretion. The sensory neurons in the trigeminal ganglion which project to the muscles of mastication of the cat were studied using the retrograde transport of horseradish peroxidase. Using this technique, distribution curves were obtained for the appearance of metaphase cells in successive generations, and mean cell cycle time (11 hr) was determined.

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Extraperitoneal surgical drainage was done and systemic antibiotics were given. A Golgi apparatus-enriched fraction obtained from lactating rat mammary glands has been used to investigate the binding transport of oestrone sulphate using radio-labelled ligand. Some articles have suggested that copper containing IUDs have also cause a variety of skin disorders. Apamin, a peptide of bee venom, was shown to inhibit the relaxant responses of guinea-pig taenia caeci to ATP, noradrenaline, adenosine and, less effectively, to stimulation of noradrenergic inhibitory nerves.

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These observations indicate that BiP is not constitutively expressed in terminally differentiated plant organs. No difference was seen in the number of contacts with general practice. Antioxidant activity of OMW samples was assessed using the recently developed Co(II)/ethylenediaminetetraacetic acid (EDTA)-induced luminol chemiluminescence analytical protocol, while the total phenolic load was measured according to the Folin-Ciocalteu method. Collectively, our work uncovers a previously unrecognized subunit of the MICOS complex, necessary for CJ integrity, cristae morphology, and mitochondrial function and provides a resource for further analysis of MICOS architecture.

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In vivo-in vitro model to assess chloroquine activity in monkeys. The method was applied to determine cAMP in human urines and a catecholamine receptor system. Natural Ascaris suum infections in swine diagnosed by coprological and serological (ELISA) methods. Surgical complications with the cochlear multiple-channel intracochlear implant: experience at Hannover and Melbourne.

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Evaluation of elastase and alpha 1-proteinase inhibitor-elastase uptake by polymorphonuclear leukocytes and evidence of an elastase-specific receptor. TSH, previously shown to induce a gradual amine release from mast cells within, but not outside, the thyroid, evoked a gradual increase in thyroidal, but not in muscular, uptake of 86Rb. Complexities in the brain circuitry (including the subdivisions of the nucleus accumbens) and differences between behavioural models help to rationalise the current controversy.

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In CP, ACA predictive value for metamorphosis was poor: only three of 13 patients had ACA within 1 year before BT, and only two of 11 within 1 year before AP. We present an approach to completely stop terahertz radiation in an optical system with a gyroelectric semiconductor. Number of Nanoparticles per Cell through a Spectrophotometric Method - A key parameter to Assess Nanoparticle-based Cellular Assays.

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Levels of C3a in plasma are currently measured by a competitive inhibition radioimmunoassay (RIA) in which 125I-C3a is used as a tracer. Dietary glycemic load, carbohydrate, sugar, and colorectal cancer risk in men and women.

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Limited transfer and handling steps eliminate sample losses, and surface-tethered enzymes (and autolytic fragments) are prohibited from interfering with analytical signals in the mass spectra. The possible influence of the central nervous system on renin release was investigated by simultaneously monitoring the PRA and the changes of the sleep-wake cycle. Five hundred forty-seven noninstitutionalized people aged 70 and older. Part II is a separate paper reviewing some analysis strategies for dose response studies.

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Disparate effects of tumor necrosis factor-alpha/cachectin and tumor necrosis factor-beta/lymphotoxin on hematopoietic growth factor production and neutrophil adhesion molecule expression by cultured human endothelial cells. Because the treatment modalities are completely different between the 2 diseases, we emphasize that 2 different orthogonal planes are necessary for diagnosis using computed tomographic image examination.

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Despite progress in orthopedic surgery and some success in development of chondrocyte transplantation treatment and in early tissue-engineering work, cartilage regeneration using a biological approach still remains a great challenge. Mice deficient in perforin, a key mediator of lymphocyte-mediated cytolysis, have recently been generated using the gene knockout technique.

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In this review, the immunological principles underlying mucosal vaccine development will be discussed, and the application of mucosal adjuvants and delivery systems to the enhancement of protective immune responses at mucosal surfaces will be reviewed, in particular those envisioned for oral and nasal routes of administration. So-called idiopathic intracranial hypertension of drug origin should be suspected Cartilage surfaces of the metacarpal side of one fetlock joint were surgically damaged (grooved), followed by intermittent forced loading of the experimental joint.

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Differential distribution of leaf chemistry in eucalypt seedlings due to variation in whole-plant nutrient availability. At the end of the stimulus treatment phase, cows in high- or low-stimulus groups had significantly greater (P less than 0.05) reluctance to enter the stocks and had higher heart rates during the period before they were given the stimulus.

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Achieving pH control in the critically ill patient: the role of continuous infusion of H2-receptor antagonists. On the contrary, both the force distribution and overall magnitude is modified for the fast moving aggregating cells. A follow-up study of the earliest radiological changes in rheumatoid polyarthritis.

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Five thousand one hundred seven infants aged 3-19 months in 2004. In Experiment 2, postlexical semantic matching of the prime and the target was encouraged by requiring subjects to respond to both of them at the same time. coli recA protein, by fusing spleen lymphocytes from immunized mice with P3X63-AG8 myeloma cells.

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Release of copper from embedded solid copper bullets into muscle and fat tissues of fallow deer (Dama dama), roe deer (Capreolus capreolus), and wild boar (Sus scrofa) and effect of copper content on oxidative stability of heat-processed meat. Gene-expression levels for furin, urokinase plasminogen activator, MMP-2, MMP-9, MT1-MMP, and TIMP-2 were determined by real-time PCR. Carnitine 100 mg/kg resulted in an increase in mean aortic blood flow.

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The structural changes in the polar head group region of unsonicated bilayer membranes of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine and 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine produced by addition of cholesterol have been determined using deuterium and phosphorus-31 NMR. Nanofibers particularly polymeric nanofiber prepared by electrospinning process can be used as carriers for the controlled drug delivery of bioactive molecules such as cytokines, growth factors, anticancer drugs, enzymes and certain vitamins. ET 1 was, however, found only sporadically among strains isolated from foods and food factories. Generation of mink cell focus-forming viruses by Friend murine leukemia virus: recombination with specific endogenous proviral sequences. The number of genes that have been demonstrated to change expression in response to drugs has increased rapidly in recent years owing to microarray technology, which allows measurement of thousands of genes at one time.

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Is optical frequency domain imaging a promising modality for diagnosis of erosion? University of Pennsylvania Health System report is strong recruiting, fund raising and communications tool.

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The presence of antiidiotypic antibodies in these sera was investigated using the mixed lymphocyte culture (MLC) inhibition test, in which spleen cells from normal Balb/c mice were tested for proliferative responses to x-irradiated C3H stimulator cells in the presence of sera from transfused mice. Mouse-human somatic cell hybrids that lose (segregate) human chromosomes produce only mouse 28S ribosomal RNA even when they retain copies of the human chromosomes that contain the genes for 28S ribosomal RNA. Subjective symptoms and other eye complications were assessed and retrospectively compared in patients belonging to a proprietary membership system who switched from 2-week frequent replacement (2WFR) wear to daily disposable (DD) lens use. CSF HVA was higher in those taking drug overdoses, but only in depression (and less markedly in schizophrenia).

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Nine Mongolian TBEV strains were isolated from tick homogenates. Ongoing efforts are now addressing the epidemiology of GAS infections in developing countries so that new vaccines can be designed to prevent the infections that may trigger ARF and RHD. Acute and subacute complications of TB disease are attributable to structural damage or vascular compromise caused by Mycobacterium tuberculosis, as well as metabolic abnormalities and host inflammatory responses.

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Tea intake has been associated with lower risk of mortality and morbidity in some, but not all studies. To determine the effects of the opioid peptides, beta-endorphin and dynorphin A, on airway smooth muscle function and its possible modulation by tissue peptidases, we studied canine bronchial segments under isometric conditions in vitro. However, if children start attending day-care before the age of 1 year, they experience a lower risk of being hospitalized during their preschool years. Failure of proglumide and cimetidine to affect this stimulation ruled out the participation of histamine and/or gastrin. Five novel alleles of the Escherichia coli dnaA gene that were temperature sensitive in maintenance of pSC101, a plasmid that is dependent on this gene for replication, were isolated.

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The etiology is widely debated because of the rare nature of the condition. The sulfated octapeptide of cholecystokinin (CCK-8, 4.0 nmol/kg ip) also reduced food intake only in the controls. Cold target blocking studies confirmed the NK specificity of the observed cytotoxicity. To determine the psychometric properties of the Duke Health Profile (DHP) in neuromuscular disease. Equivalent submaximal coronary vasodilator doses of acetylcholine and adenosine were compared for effects on transmural blood flow.

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Chevron bone graft procedure for the correction of brachymetatarsia. The two internal Pi peaks, which have line widths of approximately 60 Hz, have been assigned to spore and epiplasmic compartments, respectively.

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This concept is gaining attention because it is a cost-effective alternative to cancer treatment. Curvilinear structures, such as vasculature and spicules, are particularly salient structures in the breast, and being able to accurately position them in 3D is a valuable goal. Proteomic characterization of harvested pseudopodia with differential gel electrophoresis and specific antibodies.

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Evolutionary relationship between the T3 chains of the T-cell receptor complex and the immunoglobulin supergene family. Aortofemoral reconstruction yields total reflief of the symptom complex. 103 consecutive patients with a presumptive diagnosis of antidepressant overdose were enrolled and prospectively followed. A therapy with pentavalent antimony brought rapid improvement in clinical symptoms and led to complete recovery. We postulate a preexisting weakness in the retinal vein wall as a predisposing factor to rupture.

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This technique is only in its infancy, but technologic advances are rapidly making it a major force in the field of diagnostic imaging. The mean dose to the parotid glands depended on the beam geometry and tumor location and did not depend on the number of segments. Comparing DOM adsorption to SAM-coated sensors that systematically differed in surface charge and polarity characteristics showed that electrostatics dominated DOM-surface interactions. Atropine and haloperidol blocked this action, whereas phenoxybenzamine and propranolol were ineffective.

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Interferon-gamma-inducible protein, 10 kDa (IP-10), chemoattractant towards activated T-lymphocytes, was significantly elevated at 6 and 12 hr postinjury. The patterns of genotypic variation among single-nest workers suggest that polygyny is functional in all the three species. This is a rare report of a hypoglossal schwannoma in a young patient who was treated with a multimodality approach in order to minimize risks. Fracture healing is a complex process that in particular cases is impaired. This study identified 4 cases of ND in our cohort of diabetes children and confirmed their molecular diagnosis.

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Liver dysfunction and probable manganese accumulation in the brainstem and basal ganglia. Lymphocyte proliferation in response to mitogenic stimulation was reduced to a variable degree in all patients, indicating a general impairment of cell-mediated immune responsiveness, although mitogen-induced production of the lymphokine migration inhibitory factor (LIF) was normal in most cases. The effects of calyculin A upon calcium-, guanine nucleotides- and phorbol 12-myristate 13-acetate-stimulated ACTH secretion from AtT-20 cells.

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The membrane fractions were obtained by differential centrifugation and a subsequent separation in sucrose density gradient. However, equilibrium binding and kinetic dissociation experiments suggest that the two factors bind to delta E3 independently, rather than cooperatively. Transforming growth factor beta (TGF beta) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblasts. However, to disentangle between competing hypotheses on how selection operates on male x female molecular interaction leading to fertilization, we need to find male and female molecules that are partners in fertilization. Influence of diethyl maleate-induced loss of thiols on cefmetazole uptake into isolated epithelial cells and on cefmetazole absorption from ileal loop of rats.

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Development of a cognitive behavioral group intervention programme for patients with multiple sclerosis: an exploratory study. The effect of renin-angiotensin blockade by irbesartan or ramipril in combination with diuretics on quality of life (QoL), regional and global systolic and diastolic function was assessed in HFNEF patients.