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Antioxidants in myocardial ischemia-reperfusion injury: therapeutic potential and basic mechanisms. By their chromatograpi- behaviour the antibiotics were close to macrolides.

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Vertebral instability and the neuroaggressiveness produced by the occurrence of cervical metastasis in a neoplastic patient during remission or quiescence of the disease is rare, but it may negatively influence the prognosis of the patient and drastically reduce his or her life expectancy. A self-administered version of a brief measure of suffering: first aspects of validity. We advocate wider use of this technique in appropriate circumstances. Transport calculations using a neutral particle transport code have been made to determine the dose-depth distributions within a simple head phantom for five different incident neutron beams. To study the predictive value of clinical criteria and polymerase chain reaction (PCR) assay of cerebrospinal fluid (CSF) for the diagnosis of cytomegalovirus (CMV)-related neurological disorders during AIDS.

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Two cases of malignant effusion treated successfully by loco-regional administration of carboplatin The formation of these two isoforms is explained by RNA editing at nucleotide 1012 which changes the stop translation codon UAG at amino acid residue 196 into the codon UGG for tryptophan and extends the open reading frame for the synthesis of p27. Study of cytochemical markers ACP and ANAE in childhood lymphoma and leukaemia.

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However, the elements implicated in the adenosine-dependent purinergic regulation of cholangiocytes are not known. Fusion of the collagen type I alpha 1 (COL1A1) gene with the platelet-derived growth factor B-chain (PDGFB) gene has been pointed out in dermatofibrosarcoma protuberans (DFSP). In three HS families, one haploid set of beta-spectrin mRNA was undectectable.

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The dopamine-3 receptor (D3-R) has a limited expression pattern that is restricted largely to the mesolimbic dopaminergic system. Therefore, these results show that Ecsit functions as an essential component in two important signal transduction pathways and establishes a novel role for Ecsit as a cofactor for Smad proteins in the Bmp signaling pathway. The compression and dissolution properties of APAP-TMG were similar to that of the APAP-OXA cocrystal.

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Rod Packing in Chiral Nematic Cellulose Nanocrystal Dispersions Studied by Small-Angle X-ray Scattering and Laser Diffraction. To investigate the effects of pravastatin, a potent 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, on impaired endothelium-dependent relaxation induced by lysophosphatidylcholine (LPC), the major component of oxidized low-density lipoprotein, in rat thoracic aorta. SR 33589, a new amiodarone-like antiarrhythmic agent: electrophysiological effects in anesthetized dogs. Constitutive prostaglandin secretion, which sometimes masks antigen-presenting capacity, was also demonstrated.

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Catheterization and cardiovascular diagnostics on safety of coronary ultrasound angioplasty. After unenhanced T1- and T2-weighted spin-echo (SE) and FLASH imaging, 4 mL of a 0.5 mol/L solution of a gadolinium chelate (tetraazacyclododecanetetraacetic acid) was injected into the superior mesenteric artery during FLASH imaging in a single breath-holding period. Effect of eel calcitonin on serum electrolytes in the eel Anguilla japonica. Immunoprecipitation studies using transfected COS-7 cells indicate that BRII binds to caveolin-1 alpha and beta. We ended up with a single model structure where all the lysine residues of cytochrome c that are known as functionally-relevant were involved in forming salt bridges with acidic residues of Apaf-1.

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IL-18 levels correlate with the disease activity of rheumatoid arthritis (RA) and osteoarthritis (OA). Broad-host-range IncP plasmid RK2 possesses a series of operons involved in plasmid maintenance, whose expression is coordinated by a number of regulators, most of which are encoded in the central regulatory korA-korB operon. In addition, we present results of our preliminary experimental investigation on the partitioning of bacteriophages, including phiX174, P22, and T4.

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FDG PET did not allow reliable diagnosis of metabolic disturbances for individual patients. Significant differences between the two groups were noted on all measures except fluency.

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Their etiology are vascular, anoxic, infectious or traumatic changes in the brain. Mouse immune interferon enhances fibronectin production of elicited macrophages.

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A limiting-dilution system is described that makes use of T cell growth factor T cell expansion and allows the determination of precursor frequencies for various regulatory and effector T cells in nonimmune, polyclonally, or specifically activated T cell populations. Fibronectin and type IV and V collagen were located in close proximity to these cells. Proportion and timing of arteriovenous (AV) vascular access creation (fistula or graft) 12 months prior and up to 24 months after starting hemodialysis therapy. GPs gave only a mixed level of support to the idea of further expansion. RIA and immunoprecipitation were used for anti-TPO and anti-GAD detection respectively.

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The body mass index (BMI) and waist circumference (WC) are a risk of hypertension, but their potentially multiplicative effect on hypertension is underexplored. The present report describes a case in which this zone of diminished density was a large cystic astrocytoma, overlying a subfrontal meningioma. An evaluation of iontophoretic application of fluoride for tooth desensitization. Telomere elongation by telomerase is repressed in cis by the telomeric protein TRF1.

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The autonomic control of submandibular secretion has been investigated in fully weaned, anaesthetized calves 7 weeks after birth. Characterization of serum protein components from Donryu rats which were immune to hepatoma AH-66 tumor cells. Retention of messenger activity of RNA phage RNA following RPC-5 chromatography. Injection of endotoxin-free human serum albumin into the vitreous produced a severe inflammation detectable after 7 days and maximal between 12 to 21 days.

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In the present study, we have analyzed both the cis-activating element and transactivating factors involved in Tax activation of the FasL promoter. They also exclude the de novo generation of prebursal stem cells in the yolk sac. Antibodies made to the recombinant protein immunoprecipitate a late glycoprotein with a mobility of approximately 150,000 Da from EBV-producing cells. These data demonstrate that a network of interacting cells analogous to that proposed to regulate antibody synthesis is also involved in regulating some nonlymphoid cell products.

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Triaxial strain gauges and video extensometer were used to measure distal cortex strains and implant stability in eight reconstructive techniques replicated with synthetic femur under a load of 2030N. Six males, ages 31-58, with ischemic vascular disease of the lower extremities, underwent treadmill testing with measurement of oxygen uptake at 45-60 seconds of exercise (VO2-45-60) as the test score. Determinants of short stature in normal children at the age of two years: a case-control study in a community in Jerusalem. It contains two subunits with a molecular weight of 47000 as determined by sodium dodecylsulfate/polyacrylamide gel electrophoresis.

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Taste perception, associated hormonal modulation, and nutrient intake. Purification and characterization of the oxygen-sensitive 4-hydroxybutanoate dehydrogenase from Clostridium kluyveri.

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Early insulin intervention may preserve residual islet beta-cell function in LADA. To investigate the function of actin assembly in vivo, we altered the levels of capping protein in Dictyostelium cells and found changes in resting and chemoattractant-induced actin assembly that were consistent with the in vitro properties of capping protein in capping but not nucleation.

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The appearance of Au18-fibronectin in these fibrillar networks and disappearance of clusters of Au18-fibronectin suggest that Au18-fibronectin complexes are arranged into matrix at specific regions of the cell surface. At a lower dose level (50 mug) ADTN, injected intracerebroventricularly, had little effect on the locomotor activity of normal or sham-operated rats. It has been demonstrated that biologically active estrogens are locally produced from circulating inactive steroids in an intracrine mechanism in the breast carcinoma. No evidence for prolonged latency of saccadic eye movements due to intermittent light of a CRT computer screen. MR images of 17 patients who were candidates for surgery were correlated with pathologic specimens.

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Histological examination of ovaries revealed large and well formed CL, the diameters of which were significantly (P less than 0.05) increased. Thus, T-cell growth in gels seems to be a matter of recognition between activated blast cells rather than monoclonal growth.

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Cardiac electrophysiologic effects of diltiazem in dogs receiving either enflurane or chloralose anesthesia. We show that the presence of a regulatory cis-acting element that flanks the core octamer site and dictates selectivity in the response to Vmw65 (VP16), while dispensable for POU binding per se, induces a conformational alteration in the nature of the POU domain in the DNA complex. The chi-square test was used to analyze the correlation between AN ratio and middle ear pressures and Wilcoxon test was used to compare the changes between the mean AN ratio values, and mean middle ear pressures (including A and C type tympanograms) before and after medical therapy. There is an urgent need for randomized trials to guide policy and clinical practice. To identify the frequency of geriatric syndromes in patients with a non- recent hip fracture seen at a primary health care unit in the state of Puebla, Mexico.

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Because of these disadvantages, alternative methods of neutrophil collection should be considered when possible. The ED50 for methotrexate was similar in both A2780S and A2780DDP cells (1.2 microM). Prevention by allopurinol of the conjugation of exogenously administered haematin with apo-(tryptophan pyrrolase) renders this haem available for further repression of 5 aminolaevulinate synthase. We hypothesized that staged chemoprophylaxis using LMWH in hospital followed by aspirin after discharge was safe and effective for the prevention of venous thromboembolic events (VTE). The perspective of immunoblotting has already found wide application in basic research.

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The neoplastic lymphatic cells in the skin infiltrates were T-cells of the helper/inducer phenotype and thus differed morphologically and by immunological markers from the neoplastic cells in peripheral blood and bone marrow. The changes of brachial arterial endothelium-dependent diastolic function (FMD) before and after treatment was observed, the changes of blood levels of nitric oxide (NO), endothelin-1 (ET-1), C-reactive protein (CRP) and lipids were also recorded. The agarose plate method was also adopted to measure levels of FIX antigen (IX:Ag) in plasma. The use of DHE avoids several problems associated with opioid analgesia, including dizziness. Prolonged mercury treatment also causes a gradual decrease in staining intensity for sulphated glycosaminoglycans in the outer border of the most superficial layer epithelial cells.

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bcl-2 protein was also induced in glial cells, mainly microglia, border zone of the infarction. An epidemiological index of developmental defects of dental enamel (DDE Index). Apoptotic effects of COM and Western blotting both revealed that COM extract dose-dependently increased the expression of p53, p21,Bax and caspase-3.

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Initially, two enhancer elements, CREST1 and CREST2, were identified downstream of the isl1 locus in the genomes of fugu, chick, mouse, and human by BLAST searching for highly similar elements to those originally identified as motor and sensory neuron-specific enhancers in the zebrafish genome. A high concentration of extracellular magnesium (10 mM) decreased basal and carbachol-stimulated calcium levels, whereas low magnesium levels (0.2 mM) had the opposite effect. Effective percutaneous transluminal denervation procedures in this population would need to be circumferential rather than interrupted, and to mediate tissue damage to depths beyond 2.5 mm from the tunica intima. LPS regulation of specific protein synthesis in murine peritoneal macrophages.

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Radioimmunoprecipitation and Western blot (immunoblot) analyses indicated that these antibodies were directed against both the proteins and lipooligosaccharide (LOS) in the NTHI outer membrane. Secondly the TVA is time-consuming as the chamber needs to stabilize after each polarizing voltage change and since it must be performed for each beam quality. Clinical characteristics of obstetric paralysis of the arm in infants during the neonatal period

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lactis MG1363 and in the silage inoculum strain Lactobacillus plantarum E19b. This chiefly occurred as a mild, self limited disease, interspersed with discontinuous pockets of blinding disease. Discussion on education in the Danish Nursing Council congress 1978: broad membership discussion as a basis for educational policy In order to test whether the nitrogen/ammonium moiety in the dopamine molecule is required for dopaminergic activity, we have synthesized two sulfonium analogues of dopamine and tested them for biological activity in an in vivo and in an in vitro system.

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For a health establishment, elimination of drugs is not included as part of waste disposal. For each combination of pulse and blood pressure in group 1, a change in pulse alone had the same or higher sensitivity with at least the same specificity. In developed nations, with rapidly decreasing age of viability, and alternative modes of childbearing, threats to Apgar are more ominous today than before. Community perception of rural hospital conversion/closure: re-conceptualising as a critical incident. Growth of all isolates tested was completely or partially inhibited by P.

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Treatment of trigeminal neuralgia with retrogasserian glycerol injection. Hindlimb analysis also showed a greater content of fat and a lower content of muscle in the obese. Methodical aspects of formation of diagnostically related groups for inpatient therapeutic-prophylactic institutions Top 10 nodes in the regulatory network were acquired and their sub-networks were extracted from the whole network. The most informative texture parameters on evaluating changes in myocardium structure proved to be: local mean intensity, the form of local histogram, local variance and run-length nomuniformity.

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A consistent up-regulation of nPKC-omega in conjunction with overall down-regulation of nPKC-epsilon was observed in both models. Significance of a cysteine-rich domain for functional expression of dystrophin protein. Nonetheless, according to a number of clinical reports, methods that highlight movement sequences and methods that heighten the melodic line and slow rate are the ones that have gained the greatest favor in the treatment of children with DAS and adults with acquired apraxia of speech. Fronto-orbital fibrous dysplasia is a progressive disease whose growth does not cease at puberty. The effect of ND, VCR and 5-FU on the growth of aggregates in culture on gyrotory shaker was reversible within 1 and 2 days respectively.

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An approach is developed that can be used routinely as an alternative to point-charge modelling schemes for the assignment of distinct lines in (23)Na NMR spectra to specific crystallographic sodium sites. Pharmacokinetic analysis of factors determining elimination pathways for sulfate and glucuronide metabolites of xenobiotics II: Studies with isolated perfused rat liver. Electric aspects of pseudonecrosis observed in primary myocardiopathies Volume replacement reversed haemoconcentration, restored PCWP and produced some haemodynamic improvement, although in general, severe cardiovascular depression persisted throughout a three hour observation period.

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We have studied 22 different mutants, 14 in detail, distributed throughout the length of the btuB gene. Eventually all the patients developed wide-spread systemic metastases. As a precursor to future clinical trials, the therapeutic efficacy and blood vascular side effects of VEGF-C and VEGF-C156S were compared in a large animal model of secondary lymphedema. Stereoselective reduction to (S)-citronellol, E/Z-isomerization to nerol, oxidation to neral/geranial and glycosylation of the corresponding monoterpene alcohols could be demonstrated. Effects of placental weight and maternal nutrition on the growth rates of individual fetuses in single and twin bearing ewes during late pregnancy.

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The program can be applied for two states Markov Chain with any order and any number of covariates depending on the PC capabilities. Aortic valve and aortic diseases: update on current treatment options. Neurosteroids such as dehydroepiandrosterone sulfate and pregnenolone sulfate attenuate the CFS response and have anti-amnesic effects, the effects being mediated via sigma 1 receptors. Migraine-like attacks in child with Sturge-Weber syndrome without facial nevus. The present results suggest that GDNF is likely to act upon receptors present in several autonomic and sensory neuronal populations.

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Administration of GnRH at the moment of artificial insemination can improve the conception rate. bFGF and its low affinity receptors in the pathogenesis of HIV-associated nephropathy in transgenic mice. The meeting offered a unique opportunity for exchange between different scientific and medical communities. A biopsy procedure for determining filet and predicting whole-fish mercury concentration.

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Second, the use of mithramycin in the treatment of severe hypercalcemia is emphasized. However, the carbachol-induced negative inotropic effect was decreased. Animals were randomized to 1 of 4 treatment arms, including control groups that received conventional renal capsule suture repair with an absorbable gelatin sponge bolster (3 in group 1) or a microfibrillar collagen sheet (3 in group 2) and experimental groups that received sutureless treatment entailing fibrin sealant instillation into the knife tract augmented by an external gelatin sponge (5 in group 3) or an external microfibrillar collagen sheet (5 in group 4). Effect of spontaneous portal-systemic shunting on plasma insulin and amino acid concentrations. Organelle contact sites perform fundamental functions in cells, including lipid and ion homeostasis, membrane dynamics, and signaling.