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Hsp90 is an abundant molecular chaperone essential to the establishment of many cellular regulation and signal transduction systems, but remains one of the least well described chaperones. Good patient relations can help abate potential risk situations. The mechanism of speech perception in patients with a multichannel cochlear implant. We conclude that antigen-induced histamine release is impaired in tolerant animals.

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The results remained significant when analysed for covariance with DSM-III-R axis I diagnoses, age or sex. SDS-polyacrylamide gel electrophoresis of the LPS of virulent and avirulent strains also revealed differences in their electrophoretic mobilities. Plasminogen activator in normal subjects after exercise and venous occlusion: t-PA circulates as complexes with C1-inhibitor and PAI-1. Acute cold exposure and the metabolism of glucose and some of its precursors in the liver of the fed and fasted sheep. These results are interpreted to suggest that selection of antibody repertoires by anti-Id may occur at multiple steps of B cell differentiation.

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Prediction of response to adrenalectomy in the treatment of advanced breast cancer. A strong positive correlation was found between high FFA and low arterial oxygen tensions in all cases up to 24 hours after injury.

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Gated silicon drift detector fabricated from a low-cost silicon wafer. To describe the ophthalmoscopic and optical coherence tomographically determined retinovitreous interface before and after the development of a macular hole secondary to an accidental laser injury. The principal posttreatment ultrastructural changes observed were the reduction of mitochondrial swelling in granular cells and the reduction in the number of lipidlike vacuoles in corneocytes.

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The spectrum of bursting activity patterns varies from that termed eupnoic to that termed gasping. In two patients, the CLL was present before or coexistent with the SLE when the SLE was diagnosed, while in the third, the CLL developed 5 years after the diagnosis of SLE was first made. It has been suggested that orally derived volatile aromatic amines may be of possible diagnostic use and may contribute to the etiology or pathogenesis of periodontal disease. High-performance liquid chromatographic determination of the distribution of naturally occurring folic acid derivatives in rat liver.

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Influx (2 min) of beta-Ala was found to be linearly related to substrate concentration over the range 0.5-100 mM. Survey on haemoglobin variants, beta-thalassaemia, glucose-6-phosphate dehydrogenase deficiency and haptoglobin types in Turkish people living in Manavgat, Serik and Boztepe (Antalya). In their second year, students fit and cement bands, bond brackets, ligate archwires and fit and adjust headgears on the Simulation System.

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Wakefulness was greatly increased, light slow wave sleep was diminished and deep slow wave sleep and paradoxical sleep was abolished. In this study, we focused on lncRNA SPRY4-IT1 and investigated its expression pattern, clinical significance, and biological function in UCB. To develop an understanding of the role of each of the glycoproteins in the generation of a protective immune response, we immunized 1-week-old mice with three different preparations: a vaccinia virus recombinant (VV.ORF) that expresses both G1 and G2, a vaccinia virus recombinant (VV.G1) that expresses G1 only, and a truncated soluble G1 (sG1) protein prepared in a baculovirus system.

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Patients bridged to emergency HT on short-term MCS are exposed to an increased risk of postoperative complications and mortality. Continuous inhibition of the platelet S2-serotonergic receptors during the long term administration of ketanserin. The origin of substance P and acetylcholine projections to the ventral tegmental area and interpeduncular nucleus in the rat. It is tentatively suggested that the bulk of freshwater dissolved organic matter is aliphatic in nature, with CRAM derived from cyclic terpenoids, and MDLT derived from linear terpenoids.

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Intraoperative whole blood autotransfusion during venous thrombectomy. Testis histology, sperm numbers and morphology were normal, but NHE-null males were completely infertile with severely diminished sperm motility. Total daily energy expenditure of healthy, free ranging school children. With increasing application of targeted therapies and the development of acquired resistance, much attention is being focused on developing in vitro and in vivo patient-specific tumor models for individualized therapeutic evaluation of cancers.

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Double-labelling immunofluorescence revealed that most TH-LI neurons also contained somatostatin-LI, but TH-LI did not coexist with either calcitonin gene-related peptide- or substance P-LI. This gene, called XIST (for Xi-specific transcripts), is a candidate for a gene either involved in or uniquely influenced by the process of X inactivation. The findings in this small series support the observation in earlier reports that percutaneous repair of selected scaphoid nonunions requires only rigid fixation to achieve healing. The effects of the additive on two different manual developing solutions were evaluated immediately after mixing and at intervals of 5, 10, and 15 weeks.

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There were 46 and 44 differentially expressed proteins identified from SK-N-MC and HT-29 cells, respectively, categorized under apoptosis, stress, cytoskeletal, energy metabolism proteins and others. A total of 10 suitable kidney donors with small, unilateral nonobstructive calculi underwent live donor nephrectomy (8 open flank, 2 hand assisted transperitoneal). In all the three studies, active treatment consisted of diuretics and/or beta-blockers, usually given in combination. These data indicate that reduced dopamine delivery to the adenomatous lactotroph, either due to a primary hypothalamic abnormality or to a deranged vascular pituitary arrangement, rather than a reduced PRL sensitivity to dopamine inhibition, is the main event accounting for PRL hypersecretion in women with PRL-secreting pituitary tumors. Atrial tachycardias (ATs) after extensive ablation are increasingly common and challenging arrhythmias.

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AFM force spectroscopy reveals how subtle structural differences affect the interaction strength between Candida albicans and DC-SIGN. Pairs of animals were killed after 1, 3, 5, 7, 9 and 12 days of continuous darkness. On the other hand, baseline BP in females was controlled by two loci on Chr3 and Chr7.

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The expression levels of some connective related genes (HAS1, HYAL1, ELN, ELANE, DSP, GDF6, and IGF1) were analyzed on cultures of dermal fibroblasts using real-time reverse-transcription polymerase chain reaction (real time RT-PCR). We postulate that gradual constriction of the ductus arteriosus may play an important role in successful cardiovascular adaptation in the premature infant.

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Restoration of the vaginal flora can be significantly enhanced by the administration of live lactobacilli in combination with low dose oestriol. The aim of this study is to evaluate the clinicopathological features of metaplastic breast carcinoma and to confirm the triple negative, basal-like and/or luminal phenotype of this type of tumor by using immunohistochemical staining. Synthesis and binding of new polyfluorinated aryl azides to alpha-chymotrypsin. CRF-induced seizures and behavior: interaction with amygdala kindling. ossifragum after 2 days feeding, and their appetite for hay and concentrate was also reduced.

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In addition, 13 animals had a history of having had the disease and 112 had no history or evidence of having had the infection. Maximum levels of MT mRNA were detected about 1 hour after addition of copper ions to mycelium of N. T lymphocytes recognize foreign antigen together with allele-specific determinants on membrane-bound class I and class II (Ia) gene products of the major histocompatibility complex. Review the current evidence-based status of pulsed radiofrequency (PRF) treatment for patients with shoulder pain based on randomized controlled trials (RCTs) to provide a comprehensive analysis and a balanced view of the strengths and weaknesses of this treatment.

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Coaxial nanocable: silicon carbide and silicon oxide sheathed with boron nitride and carbon Correlation between frictional force and surface roughness of orthodontic archwires. The role of dopamine D1 receptor transmission in effort-related choice behavior: Effects of D1 agonists.

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Its onset generally occurs in individuals between the ages of 20 and 50 years. administration in a dose range of 25 to 125 microliter/kg to animals maintained for 15 days either on normal diet or a diet containing 10 ppm chlordecone (CD). Nine had clinical features of chronic inflammatory bowel disease 1 mo to 5 yr before the onset of primary sclerosing cholangitis (6 patients) or appearing simultaneously with primary sclerosing cholangitis (3 patients). Common garden experiments showed that gaping (periodic closure and opening of the shell) and attachment to the substratum differed significantly between the two lineages.

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This study compares the central nervous system effects of rat calcitonin and rat calcitonin gene-related peptide (CGRP) on gastrointestinal transit in freely moving rats. In this article, we propose recommendations to further advance the field of scoping review methodology.

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A programme of clinical work by undergraduate dental students in community dental clinics. This is a rare cause of rupture of the uterus in this population.

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Subintimal hemorrhage treated by percutaneous transluminal angioplasty. In the past, quality has been assessed by visual counting or estimation of the number of bands on chromosomes. The cytoplasm of the tumor cells contained PAS-positive, diastase-resistant granules. We have generated fluorescent biosensors for cdiA through fusion of the Spinach2 aptamer to ligand-binding domains of cdiA riboswitches. Thus, this developed testing procedure can further be used to assess special populations, including patients with brain damage who cannot do monotonous tasks for a long period of time and have language impairments.

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Individuals can be identified at work by accurate annual measures of lung function. However, these treatments induced a marked increase in peak parasite counts. Acetylcholinesterase in cell adhesion, neurite growth and network formation. A common practice used for some fixed-roof tanks that are required to use controls is to vent the tank through an activated carbon canister.

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This paper briefly reviews the functional anatomy of the basal ganglia and their relationships with the thalamocortical system. Self-reported low-energy, hip, wrist, and upper arm fractures between 1993--1999 obtained at a re-examination in 1999. Proceedings of the 1991 International Symposium on Data on Aging. The emotional pain and distress of borderline personality disorder: a review of the literature.

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Here, we report 8 WS cases diagnosed with craniosynostosis using three-dimensional cranial computed tomography. Sera from streptozotocin-induced diabetic rats contain antibodies that clearly bind glucosylated collagen.

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Suspected periodontopathic bacteria associated with broken-mouth periodontitis in sheep. The causes of spinal cord compression presumably were extramedullary hematopoietic masses.

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Further prospective longitudinal studies are warranted to confirm the potential impact of thrombus formation on AAA development and its implication on monitoring and treatment decisions in patients with AAA. We report the first isolation of PUU virus in France and western Europe from a case of NE acquired in France. Subjective need of removable denture treatment in Finnish adults. Urinary fluoride excretion was found to be constant over a period of 4 weeks in each patient.

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As we discuss in this Review, over the past two decades important insights into phagocytosis have been gleaned from studies in the model organism Drosophila melanogaster. Thalidomide and the anticholinergics, scopolamine hydrobromide and orphenadrine hydrochloride, and doxylamine succinate, an antihistamine with secondary anticholinergic action, were administered to pregnant New Zealand White rabbit does from day 8 to day 15 of gestation. In vitro, supernatants, cytosols, and membranes of renal proximal tubular cells in primary cultures had no detectable uPA activity, and lovastatin (0.1 to 10 microM) induced an increase in tPA and a decrease in PAI-1 activities and antigens.

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We report here that the homeobox gene orthodenticle (otd), which is involved in head development, could be such a gene. Assay of thromboxane production in biological systems: reliability of TXB2 versus 11-dehydro-TXB2 as targets for measurement. Both regular and phasic spontaneous discharges were recorded electrophysiologically. The high sensitivity and selectivity of mass spectrometry allow traditional assays to be minimized, thus saving time, efforts and money. The isoelectric points of IL-2 and Met-IL-2 thus obtained were determined to be 7.7 and 7.5, respectively.

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We present nnnnnin vivo volumetric depth-resolved vasculature images of the anterior segment of the human eye acquired with phase-variance based motion contrast using a high-speed (100 kHz, 105 A-scans/s) swept source optical coherence tomography system (SSOCT). Expression and localization of MUC1, MUC2, MUC5AC and small intestinal mucin antigen in pancreatic tumors.

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The main finding was a significant decrease in the peripheral T-lymphocytes in surgically- or radiologically-treated patients with a squamous-cell-carcinoma of the larynx (T1-stage). Early-onset hearing impairment is a common disability in the United States. Pregnant rats were subjected to once daily stress treatments consisting of handling and a saline injection.

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Phosphorylation by protein kinase C modulates agonist binding to striatal dopamine D2 receptors. A nationwide hospital discharge register was linked to population censuses for socioeconomic data and to the cause of death register for mortality follow up. The median serum cholesterol pre-treatment was 4.6 mmol/L (range 3-6.4). Various theoretical problems of social hygiene, its role and the current tasks of Soviet Health Administration An experience with the extensive mediastinoscopy performed in 116 lung cancer patients is reported.

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The onset, peak and end of the pubertal growth spurt were defined on the unsmoothed incremental curve of height. Even though the idea that schizophrenia is a neurobehavioral syndrome has become a mainstream position, there is no consensus on the precise nature of the cognitive and neuropsychological impairment. In contrast to short-term and high-dosed infusions of glucose or glucose substitutes, the phosphate concentration in serum was scarcely influenced. Influenza and its related illnesses remain a major cause of preventable morbidity and mortality in the elderly worldwide. Current immunoassays are insufficient for determining the whole range of the drugs abused, and a broad-spectrum screening method is therefore needed.

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A method for processing light microscopy sections for oriented ultramicrotomy. The data also suggest that homosexual identity acquisition may be a two-stage process rather than the six-stage process proposed by Cass (1979).

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This peak was not seen following injection with any of the other bacteria. Caries-preventive effects of fluoride tablets in schoolchildren four years after discontinuation of treatments.

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Thereafter they were given a daily supplement of 500 mg calcium for two years and had their bone mineral content measured every three months. This new method is objective, quick, and highly reproducible among operators with varying levels of expertise. Restriction mapping of phage lambda vectors using non-radioactive methods. All wetted surfaces of the gustometer are either Teflon, glass, or stainless steel. The broadening use of antidepressants among older Americans has not been associated with a notable decrease in the burden of geriatric depression.

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The results demonstrate that defective recombinant adenovirus vectors can induce complete protection from experimental measles infection in rats. Primary care physicians and all specialty physicians should provide primary palliative care for their chronically ill patients. The authors found the presumptive diagnosis of radiation-induced optic neuropathy facilitated by MR imaging with gadolinium-DTPA. The switch-off of end bulb NMDA EPSCs by voltage jumps to the EPSC reversal potential was very rapid, suggesting that the NMDA component arises from sites on or close to the soma. Confidentiality in the age of AIDS: a case study in clinical ethics.

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Western blotting analyses reveal that glucose-responsive 832/13 INS-1 cells express essentially no 84 kDa iPLA(2)beta-immunoreactive protein but predominantly express a previously unrecognized immunoreactive iPLA(2)beta protein in the 70 kDa region that is not generated by a mechanism of alternate splicing of the iPLA(2)beta transcript. Red blood cell aging--membrane skeleton alteration and IgG receptor expression. FTFT revealed that after SD, mean spindle amplitude was enhanced, while spindle density was reduced. However, we found that the predicted structure of the Arabidopsis CDKC2 protein is more similar to the mammalian cdc2-related kinase, CRK7, than to CDK9. The 17q breakpoints in three CMPD1 translocation cases map 50 kb or more from SOX9.

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Therapeutic Partnership stands in direct contrast to the notion of lifetime advocacy and other more traditional treatment approaches. Since LC neurons form dopamine during noradrenaline biosynthesis, and DR neurons produce dopamine from exogenously administered L-dopa, our results indicate that dopamine produced in LC and DR neurons may be degraded, at least in part, by MAO. Fc-depleted vs intact intravenous immunoglobulin in chronic ITP.

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Cytokinetics of mononuclear phagocyte response to listeriosis in genetically-determined sensitive and resistant murine hosts. Test results were classified into three general patterns and a Difference Ratio Quotient (DRQ) expressed the relationship between binaural acoustic reflex and pure tone thresholds. Based on the data available in the literature and their own data, the authors analyzed the effects of retinol on the metabolism of genotoxicants and described possible mechanisms of its antimutagenic and anticarcinogenic action.

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It is possible that a partial depolarization of the cell membrane is the common mechanism for their reciprocal potentiation. The presence of multiple subclones contributes to increase in fitness and robustness of a cancer, which is reminiscent of the stability in ecosystems.

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Tissue volume does not increase in proportion to lung size, as would be required if larger lungs just had more alveoli. During intrathymic T cell development, elimination of autoreactive T cell clones by programmed cell death (PCD or apoptosis) is an essential mechanism for self tolerance.