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Toplep (Topiramate)

Toplep is a prescription drug. It comes in four forms: immediate-release tablets, immediate-release sprinkle capsules, extended-release capsules, and extended-release sprinkle capsules. All forms are taken by mouth. Toplep oral tablet is available as the brand-name drug Toplep. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug. This drug may be taken in combination with other drugs to treat epilepsy.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Current concepts related to sickle cell disease and its treatment. Due to the geographical isolation of the island it is likely that these patients share a common ancestor. Cost-effectiveness of coronary CT angiography in patients with chest pain: Comparison with myocardial single photon emission tomography.

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We propose the concept of pseudo-TK to distinguish this type of keratinization from intrinsic TK. Integration of nutrition and family planning into primary health care. Eight patients without significant disabilities in all 4 parameters returned to normal life.

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Preference for direct homolog-directed interactions at interstitial chromosomal regions was ambiguous, perhaps as a consequence of chromosome flexibility and the constraints and dynamic nature of the nucleus. The static dielectric properties of dense ionic fluids, e.g., room temperature ionic liquids (RTILs) and inorganic fused salts, are investigated on different length scales by means of grandcanonical Monte Carlo simulations. The benefits of rehabilitation therapy following CCL surgery are multifaceted including pain relief, decreased inflammation and swelling, increased tissue flexibility, strengthening, improved proprioception, improved limb and joint biomechanics, and improved weight-bearing.

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Frequency-doubling perimetry may detect early glaucomatous visual field defects. Microinjection of pp60v-src into Xenopus oocytes increases phosphorylation of ribosomal protein S6 and accelerates the rate of progesterone-induced meiotic maturation. The sedative and calming role played by massage and relaxation can not occult the longterm improvement of functional rehabilitation. SIgA is thought to play a major role in host defense at these surfaces by inhibiting the colonization of potentially pathogenic microorganisms.

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Although all six of the antibodies reacted with the apoprotein when it was prepared in a nonionic detergent known to maintain the secondary structure of the protein, three of the six antibodies showed partial or total loss of activity with NaDodSO4- delipidated apo B. This review will discuss recent evidence which shows that connexins play a role in regulation of the pulmonary vasculature and that dysregulation of connexins may contribute to PAH pathogenesis. This mechanism may be interpreted as due to concealed ventricular bigeminy caused by a ventricular ectopic focus which is surrounded by two different zones of block: a proximal zone of 2:1 block, and a distal one in which the block occurs irregularly. In vitro and short-term in vivo characteristics of a Kel-F thin film modified glucose sensor. The levels of IgG antibody to Bacteroides gingivalis was measured by ELISA.

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This helper activity was insulin-specific in both elicitation and expression. Kernel sparse representation-based classification (KSRC) is a nonlinear extension of SRC, which makes pixels from different classes linearly separable. A resting perfusion defect detected during radioisotope myocardial perfusion imaging is generally thought to represent myocardial infarction. DNA-PKcs phosphorylates hnRNP-A1 to facilitate the RPA-to-POT1 switch and telomere capping after replication.

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Assays using cell culture supernatant fluids showed immunoblot sensitivity was 10(5) - 10(6) PFU/ml. The unicellular pathogenic protozoan Trypanosoma brucei gambiense is responsible for the chronic form of sleeping sickness.

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Concurrent radiotherapy and chemotherapy is the most promising primary chemotherapy approach to prolong survival of patients with locally advanced resectable and unresectable disease. On account of its easy access in aqueous solution to the two states ferrous (FeII) and ferric (FeIII), iron is ideally suited for the activation of molecular oxygen. BAYESIAN ANALYSIS TO EVALUATE TESTS FOR THE DETECTION OF MYCOBACTERIUM BOVIS INFECTION IN FREE-RANGING WILD BISON (BISON BISON ATHABASCAE) IN THE ABSENCE OF A GOLD STANDARD.

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The social ecological model provides a framework to assess the individual and contextual factors influencing the risk for falls. N-methyl-D-aspartate neurotoxicity in hippocampal slices: protection by aniracetam. Experiments were designed to elucidate whether or not these disturbances of autonomic nervous system were induced by inflammation and accelerated by stimulant diets. Experimental acute hypoxia in healthy subjects: evaluation of systolic and diastolic function of the left ventricle at rest and during exercise using echocardiography.

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Phase Behavior of Resveratrol Solid Dispersions Upon Addition to Aqueous media. Ontogenesis of androgen receptors in the mouse submandibular gland: correlation with the developmental profiles of circulating thyroid and testicular hormones.

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The clinical signs were first to suspect the thrombotic complication. Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis.

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Serum obtained from rats with polyvinylpyrrolidone-induced sterile inflammation contains granulopoiesis-stimulating activity (GSA). Compound 1 was found to inhibit the accumulation of the LPS-induced pro-inflammatory IL-1b and NO production by down-regulating the expression of iNOS protein in RAW 264.7 macrophages.

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Moreover, the mirror glasses can be easy applied in therapy and research. The description of an aberrant immunophenotype was the criterion used to define the malignant nature of any CSF cell population. The importance of the culture medium on human dental pulp cell attachment. Tumor necrosis factor and endotoxin can cause neutrophil activation through separate pathways. Blockage of PBD for 4 hours and secretin (0.2 CU/ infusion caused a significant rise in portal serum amylase and cathepsin B levels, pancreatic water content, and pancreatic amylase content, as well as redistribution of cathepsin B in acinar cells.

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Exogenous lactate is essential for metabolic activities in isolated rat spermatocytes and spermatids. It is concluded that the pig pancreas responds to alcohol as has been described in other animals. A cross-sectional study was conducted from January 2013 to January 2014.

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The most exciting advances have come from the opportunity to utilize nutritional support as a means of investigating the basic mechanisms by which the cancer patient disposes of exogenously delivered substrate. The mechanism underlying the hyperthermic response to low doses of morphine has been investigated in rats.

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723 randomly selected New South Wales residents aged 18 years and over completed a telephone survey in November 2001. These findings will not only aid in managing patient expectations, but our methodology provides a foundation for future objective studies of the breast form. Progress and problems in the development of vascular prostheses. The target diagnostic spectrum is broad, and the effect appears within days when it occurs.

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In this study, we improved the immortalization method by CD19 and B-cell receptor (BCR) co-ligation. Specificity control experiments indicated that the antibody could be absorbed with human GH but not with human prolactin. We show here that NO and its metabolites arginine and citrulline are already involved in juvenile obesity that may contribute to atherogenesis via reduced bioavailability of NO. Elevation of absorption values of an infarct following contrast media primarily occurs in the first month after onset, and may be occasionally confused with a tumor.

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Vertebral involvement quantification, neurological status, general health status and primary tumor histology are factors to set surgical planning and therapeutic targets. Experimental findings from several investigators are used to determine the mechanical and electrical generalized stiffness coefficients described by the model. Based on binding characteristics established for the predominant Qa-1-binding peptide, Qa-1 determinant modifier (Qdm), we also examined the possibility that Qa-1 binding peptides may be encoded in the preproinsulin leader sequence. All patients underwent endocrinological evaluation by measuring plasma cortisol and aldosterone levels to assess adrenocortical function.

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Uterine action after induction of labour with oral prostaglandin E2 tablets compared with intravenous oxytocin. However, the signaling mechanisms regulating the activation of these cytokines during bacterial infections remain poorly defined.

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An all-glass improved vaccum collector for fungal spores is described and its merits mentioned. ANP induced dose-related effects on systemic and renal hemodynamic, as well as urinary electrolyte excretion, albeit with a time lag between onset and full effect. Pharmacological characterization of the apparent splice variants of the murine 5-HT3 R-A subunit expressed in Xenopus laevis oocytes.

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In addition, they present some of the results of their laboratory-based research into the control of the upper body and lower limbs in sit-to-stand and illustrate the process by which they have developed a protocol for optimising performance of sit-to-stand in training disabled individuals. Starch-processing enzymes produced by recombinant yeasts and fungi. Among the numerous demonstrated applications of ultrasonography, early pregnancy diagnosis, fetal sexing, and postpartum reproductive management appear to be promising areas for immediate application. Patient care was shared with the referring general practitioner. Whereas incubation of the nerves with normal Ringers for 2 h had no significant effect on conduction, incubation with PLA2 in Ringers caused decrements in the height of the compound action potential in a dose-related manner.

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Pacemaker mediated tachycardias (PMTs) are a well known complication of P synchronous pacing. Stimulatory action of (beta-Asp9) ceruletide on dog pancreatic exocrine secretion.

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The opening velocity (OV) was significantly higher in PHT patients 363.2 plus or minus 19.3 verus 293 plus or minus 7.3 mm/sec (p less than 0.01). Per capita numbers of child care, job training, employment services, exercise facilities, schools, and medical services were 1.5-6.4 times greater in category III vs. The victim was a 71-year-old male with a clinical history of hypertension, diabetes and gout. Mouse embryo was cultured for 24 hr in BMOC-III medium from the 8 cell stage and then transferred into the medium containing 5-bromodeoxyuridine (BrdU) for a further 24 hr. The purpose of this article is to review recent advances and future perspectives in the treatment of aSAH, early brain injury, and cerebral vasospasm.

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These include the requirement that the historical control data were obtained with animals of the same species and strain and from the same breeder. The new instrument was developed to allow assessment both of age stereotypes and of attitudes toward age-specified targets. Experience with platinum based chemotherapy and implications for curative chemoradiotherapy. Significance of digital subtraction angiography for estimation of early results of myocardial revascularization after internal mammary artery grafting

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An investigation on mechanical failure of hip joint using finite element method. We also performed detrusorectomy in dogs with normal bladders and observed a progressive decrease in bladder capacity, which became significant at 6 months. Inverted T waves were also present in one baboon and one monkey prior to any drug administration.

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Interaction with human immunodeficiency virus type 1 modulates innate effector functions of human monocytes. The novel L- and D-amino acid derivatives of hydroxyurea and hydantoins: synthesis, X-ray crystal structure study, and cytostatic and antiviral activity evaluations. The use of 11C-fluoromethane as a cerebral blood flow tracer in positron emission tomography is discussed. Expression of SARS-coronavirus nucleocapsid protein in Escherichia coli and Lactococcus lactis for serodiagnosis and mucosal vaccination. Dnmt1s protein expressed in 1-cell and 2-cell embryos is derived from the oocyte, whereas the embryo synthesizes its own Dnmt1s from the 2-cell stage onward.

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The unusual triproline sequence of myelin basic protein (100-102) is enclosed in the 14-residue hairpin loop. The same factors, rather than a deterioration of contraceptive practice following abortion, explain the higher levels of repeat abortion rates compared with first abortion rates. Preoperative anemia has been proposed as a prognostic factor for clear cell renal cell carcinoma. The research base and theoretical framework for a family support group are explored.

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Preclinical research in gynecologic malignancies has largely relied upon cloned cancer-derived cell lines and tumor xenografts derived from these cell lines. Surgical technic used in congenital fistulas and cysts of the neck applying fast-hardening polymer

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The facilitating effect of the drug reached significance in the light period but not in the dark period, possibly because the baseline food intake was higher by night than by day. Immediate postoperative enteral tube feeding following resection of the large intestine. In visual evoked cortical potentials (VECP) the amplitudes were reduced, and in one patient the latencies were slightly delayed and two patients considerably so.

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Although Bone morphogenetic protein-2 (BMP-2) is a known mediator of bone regeneration and vascular calcification, to date no study has investigated the relationship between BMP-2 and type 2 diabetes mellitus (T2DM) and its possible role in coronary artery disease (CAD). Evidence of HLA-DR antigen biosynthesis by human keratinocytes in disease. To test the hypothesis that Kupffer cells are activated after blunt femur fracture leading to altered hepatic oxygen (O2) consumption. It is proposed that many of these processes may be involved in the pathogenesis of ulcerative colitis, and therefore pouchitis may be used to study pathogenesis and treatment of inflammatory bowel disease in general and, in particular, ulcerative colitis. Primary percutaneous coronary intervention in an acute myocardial infarction due to the occlusion of the left main coronary artery.

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The organism grew on sulphate, sulphite, bisulphite, thiosulphate, dithionite, hydrosulphide, thiocyanate, L-cysteine, L-cystine, reduced glutathione, methionine, mercaptosuccinate, and lanthionine, but not on dithionate unless previously sulphur starved. The Mantoux tuberculin skin test and serology testing for hepatitis B, hepatitis C, HIV and syphilis were performed in 488 immigrants. Low-calorie foods and their significance in the prevention and therapy of obesity We reviewed the outcome of the use of DSRS in children to determine the usefulness of this operation. A detailed history regarding locality and time of symptoms is of most significance for taking the appropriate diagnostic measures and identifying, as in this case, an uncommon form of allergic rhinitis to airborne spores from moulds.

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The intercalation geometry of aclcainomycin is a hybrid between those of daunorubicin and nogalamycin. Therefore, its mechanism of action may be influenced by its regulated vectorial release to either the apical and/or basolateral compartments, where it would act on its various substrates. Postnatal changes in the role of NMDA in the isolated spinal cord of the hamster, Mesocricetus auratus. Phenotypic in situ characterization of lymphocytes in mild alcoholic liver disease.

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Indications for the various surgical procedures in hepatic echinococcosis A profound knowledge of the facial anatomy as well as extensive experience with the various filling techniques and suitable materials for the respective areas remains crucial to prevent adverse events associated with filling procedures to the human face. Spleen cells from young NZB/NZW mice spontaneously produce IgM antihistone and anti-DNA antibodies in culture, and this in vitro autoantibody production is T-cell dependent. Genetic defects are still barely known in a substantial number of adult leucodystrophies. In Experiment two there were two study conditions (enactment with imaginary objects and reading).

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Inflammatory carcinoma of the breast has been associated with a poor prognosis. Metal-metal interactions study especially showed a reciprocal antagonism between Ag and Cu. Choice of the optimal regimen for pneumatic compression in treating patients with postmastectomy edema of the upper extremity Proceedings: Physiological aspects of the hypnotic properties of steriod hormones. Changes in lung function and asthma control are well documented during the menstrual cycle.

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Given the sensitivity of rankings to selection of case-mix adjustment methods-and potential for unadjusted risk when using variables limited to current administrative databases-the HIV care community should explore optimal methods for case-mix adjustment before moving forward with public reporting. An auto-immune origin has been recently suspected but never proved.

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Breeding habitats and biting activities of Culicoides (Diptera: Ceratopogonidae) at Lake Nakuru National Park, Kenya, with special reference to C. PDS retained its tensible strength longer than other absorbable sutures, but can be used only for closing limbal incisions with conjunctival flaps in order to prevent tear hydrolysis of the suture. freundii) were active against both inducible and basal organisms (MIC less than 16 mg/l), but inactive against the derepressed mutants (MICs usually greater than 64 mg/l). Raji cell immunohistochemical assay demonstrated that both the hCGbeta and C3d3 were successfully fused. Improved leader and putative terminator sequences for high-level production of Streptomyces subtilisin inhibitor in Escherichia coli.

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Proteomic and genomic studies of non-alcoholic fatty liver disease--clues in the pathogenesis. The serum concentration of immunoreactive parathyroid hormone was abnormally low in one dog in which it was measured. Bacteremia is not adequately documented by house staff physicians in up to a quarter of patients.

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These results strongly suggest that particular FKRP mutations in the homozygous state induce structural and clinical neurological lesions in addition to muscular dystrophy. Subjects of both Group A and B received the standard of care in the form of cetirizine 10 mg OD and calamine. In other words, it captures properties of the community that influence interactivity.

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After adaptation to an artificial light/dark cycle of 12:12 h, male Wistar rats were fractionally whole-body irradiated with a dose of 2.4 Gy of gamma-rays twice a week up to total doses of 4.8, 9.6 or 14.4 Gy. Membranous Glomerulonephritis in a Patient Presenting with Chyluria, Probably due to Filariasis: How far should we investigate? Normal and tumor DNAs were obtained from thirty CRC tissues that showed abnormal expression of MLH1 and MSH2 proteins by IHC.

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Blood samples were taken twice a week over two months after abortion and from one subject over one month after removal of Norplant capsules. The medical treatment of patients with PAD is directed at intensive risk factor julphamox 500 mg modification to decrease cardiovascular morbidity and mortality. In vitro study of liver glycogen phosphorylase in rainbow trout. Maturation of blast cells in acute transformation of chronic myeloproliferative syndrome. Participant demographics and high temperature at postage had significant effects.

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In flat layers single cells and in compact layers the upper row of cells react positively. In the probe trial test, Lurcher mice preferred the visible platform rather than the more recent localization of the hidden goal. The present results favour the hypothesis of a decreased synthesis of parenchymatous BM by human adenomatous pituitary cells in comparison with normal amoxapen medicine park cells and show that these tumours are the site of an active arterial neovascularization. Sperm morphologic features as a prognostic factor in in vitro fertilization.

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The Heptest results at 12 hours after ardeparin administration indicated that the global anticoagulant effects produced by LMWH are sustained for many hours after subcutaneous dosing. At the end of pregnancy, the amniotic fluid (AF) depends basically on renal function, corresponding to fetal urine. An unusual case of tuberculous involvement of the mandible in a 22-month-old African girl is presented. This entity corresponded to type-I omeprazole 20 mg alcohol of intralobar pulmonary sequestration, as classified by Pryce. We studied the behavior of the insulin-like immunoreactivity in brains of rats and mice during the first 20 d post natum by immunohistochemistry and radioimmunoassay.

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When the IUD was removed on Day 2 of pregnancy a significant fall (p .001) in alkaline phosphatase was observed on Day 5 of pregnancy. Identification of the mechanisms involved in the pathology of nutrient deficiency provides an understanding of nutrient functions, their role in metabolism, and interactions between nutrients. HSA are zovirax otc or rx acyclovir medication a safe alternative to immediate reconstruction in a carefully selected population of skin cancer patients. Hyperglycemic and insulin release inhibitory effects of Rosmarinus officinalis. Laser-induced fluorescence (LIF) is commonly used to detect and quantify the product, marker or cell content inside each individual droplet.

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The primitive iliac artery of the primitive iliocecal artery which originates in the dorsal aorta drains into the posterior cardinal vein. This is a patient who underwent abdomino perineal resection for rectal neoplasia. The author believes that the causes of localization of the changes mostly on the side of haematoma is the local action of the non-invasive brain compressing process. Splice variations in genes coding for the use of cefpodoxime proxetil tablets iphone transmembrane FGF receptor (FGFR) result in isoforms that vary in the ectodomain, intracellular juxtamembrane domain, and the intracellular kinase domain.

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This review presents the role of combination therapy of renin-angiotensin-aldosterone system blockade on cardiovascular and kidney disease. The HS Programme made no difference to mortality in the first year of chronic dialysis. difference between prilosec and generic omeprazole paste Surgical management of extensive ano-rectal stricture with recto-urethral fistula resulting from previous ano-rectal surgery. Use of HRT was positively associated with an increased risk of symptomatic gallstones in this population. This is most likely through a reaction with the hydroxyguanidino group.

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In view of the demonstrated simultaneous release of 14C-serotonin and 3H-arachidonic acid metabolites, it appeared that either release of 14C and 3H occurs concurrently or, even if one of these events is dependent on the other, both events take place in rapid succession. Squamocin, a new cytotoxic bis-tetrahydrofuran containing acetogenin from Annona squamosa. RNA-directed agent, cordycepin, induces cell l citrulline ed dosage of amoxicillin death in multiple myeloma cells. Human manganese superoxide dismutase target sequence polymorphism and ovarian cancer. In the early years of neuroprotective research, most compounds were not designed as such but were found to possess neuroprotective activity in later studies.

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Immunohistochemical detection of very recent myocardial infarctions in humans with antibodies against heart-type fatty acid-binding protein. Early and late MMA show larger effects of inbreeding than any other trait. Preparation and characterization of N-(1-pyrenyl)iodoacetamide-labeled Escherichia coli RNA polymerase. Transrectal periprostatic lidocaine injection anesthesia for transrectal prostate biopsy: risperidone weight gain mechanism of action a prospective study.