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Topirol (Topiramate)
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Topiramate

Topirol is the brand name of Topirol, an anticonvulsant drug used to prevent seizures and reduce the frequency of migraines. While its exact mechanism of action is unknown, studies suggest Topirol might alter the production or action of neurotransmitters in the brain, suppressing the abnormal activity of the nerves in the brain that cause seizures or preventing the abnormal activity from spreading to other nerves. Other research has suggested that it might suppress the nerves directly, thereby making them less likely to fire. The Food and Drug Administration (FDA) approved Topirol to treat seizures in 1996.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Histological examination revealed four agents not previously identified. Surgery was performed in five patients with tumors following localization by CT only. We recently reported the first isolation of a tetracycline-resistant Chlamydia trachomatis strain in Toulouse from a woman treated with tetracycline. Cell-mediated inhibition of proliferation and activation of alloreactive cytotoxic lymphocytes: maintenance of response potential of precursors and dissociation between proliferation and effector function of activated cytotoxic lymphocytes.

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In intact rats infused with leptin (0.31 micromol/day), the expression of uncoupling protein-1 messenger RNA in interscapular brown adipose tissue was increased, whereas no such effect of leptin on the uncoupling protein-1 messenger RNA expression was observed in brown adipose tissue in chemically sympathectomized rats. Satisfaction and distress in a community: a test of the effects of life events.

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In total, 26 proteins associated with CD4 were identified on CEM cells. A new method for the extraction of DNA from Ascaris suum muscle has been developed. The effect of betel nut extracts on dehydrogenase activity of Streptococcus mutans GS 5. This study had the objective of estimating the costs to the public and private healthcare systems and to families of tuberculosis treatment and prevention.

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The elderly need to be incorporated into health programs and policy. A combined physical and genetic map of the cyanobacterium Synechocystis sp. Isolation of cholesterol esterase from the pancreatic juice of dogs The data were further analyzed to investigate the interrelation between such parameters as the age-distribution of patients by diseases of the respiratory system, sex and types of infection and the species and frequency of isolation of the organisms, and also the relationship between the antimicrobial chemotherapy prior to collection of clinical specimens and the species and incidence of the bacterial isolates.

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The apparent density of sperm cells may be of importance in sperm physiology. Thus receptors connected to vagal C fibers are present throughout both atria and are activated by moderate changes in pressure. It is concluded that this test, if carried out under the controlled conditions described, is sufficiently reproducible between laboratories and repeatable within laboratories to be used as a standard test.

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These results indicate increased bone turnover in hypercholesterolemic or dyslipidemic patients regardless of gender, and suggest the importance of treating hypercholesterolemia or dyslipidemia in order to prevent not only arteriosclerotic complications but also osteoporotic bone loss and subsequent fractures. The rather characteristic appearance of herniated liver on the nuclear liver/spleen scan is noted and its use rather than pneumoperitoneum is recommended. Workshop I--Fifth Joint National Committee report: how should it differ from the 1988 report? Inverse Monte Carlo (IMOC) is a unified reconstruction algorithm for single photon emission computed tomography (SPECT) that provides simultaneous compensation for attenuation and collimator divergence. Patients who became seizure-free had an earlier age at first risk than did those with persistent seizures, and tumor presence weakly correlated with postoperative outcome.

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Discriminative uptake of metals by the liver and its relation to induction of metallothionein by cadmium, copper and zinc. This might help interpretation of the characteristic species variation in susceptibility to NTE inhibitors which are known to be potent delayed neurotoxic agents. Several experimental results published in the literature showed that weak pulsed magnetic fields affected the response of the central nervous system. All adjacent intervertebral discs showed a decrease of signal intensity on the T2-weighted MRI.

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Primary hydatid cyst of peritoneum presented as abdominal lump: a rare presentation. Importance of pyrimidine nucleotide salvage pathways for DNA synthesis in skin.

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Furthermore, our data suggest that HuR level could be regulated by miR519. rhTBP-1 might possibly bind TNF-alpha and reduce the downstream phosphorylation of two main effectors of the neuroinflammatory response, p38MAPK and JNK. Its Km toward the chromogenic substrate was 0.35 mM, which agreed well with the published value for plasmin. The Trade Union Clinic is situated centrally in the large industrial area west of Melbourne. Neither patient had an acute neurologic insult other than nonconvulsive SE (NCSE) accounting for s-NSE changes.

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Genomic organization of DHR38 gene in Drosophila: presence of Alu-like repeat in a translated exon and expression during embryonic development. Reciprocal expression of pleiotrophin and midkine in normal versus malignant lung tissues.

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Clinical signification of natural killer activity in B-cell chronic lymphocytic leukemia. The distribution of tyrosine hydroxylase-, substance P- and enkephalin-immunoreactive neurons in the cat dorsolateral pons was studied using the indirect immunofluorescence method of Coons. Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor. Serum parathyroid hormone-related protein concentrations in patients with hematologic malignancies or solid tumors. In the anencephalics, alterations located within the body of the sphenoid bone led to a reduced cranial floor angle and a more vertical clivus.

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The remaining sugars were distributed in various ratios between the protein and lipid fractions. Gluteal Tendinopathy: A Review of Mechanisms, Assessment and Management. In severe pancreatic anastomotic leakage, it is better to intervene surgically as soon as possible by debridement of the distal part of the pancreas and ligation of the stump with nonabsorbable suture.

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Ontogeny of the corticoliberin neuroglandular system in rat brain. With other cell lines the molecular weights and subunit composition varies, but the major component is always of MW 125-140 kD.

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Digital retinal imaging using store-and-forward technology is used to screen for diabetic retinopathy (DR). The influence of bile salts and bile lipoprotein complex on pancreatic lipase hydrolysis of monomolecular films. Pharmacologic heart rate control during the LIMA-LAD anastomosis is not critical with the use of a surgical retractor which diminishes ventricular motion.

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Efficacy and safety of the direct renin inhibitor aliskiren and ramipril alone or in combination in patients with diabetes and hypertension. Information content of multispectral lidar measurements with respect to the aerosol size distribution.

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Microcystic adnexal carcinoma--a case report and review of the literature. To determine the incidence and risk factors for rash in Thai patients taking four different non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimens. Kinetics of methotrexate binding to dihydrofolate reductase from Neisseria gonorrhoeae.

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A stable dynamic joint is provided with the stapes capitulum (ossicle cup). All children with ventriculo-coronary arterial communications had perfusion defects both in the ventricular septum and in the left ventricular free wall. The assessment of the role of psychogenous factors in both varieties of allergic rhinitis was the main purpose of the investigation.

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Ethnic distribution of the glutathione transferase Mu 1-1 (GSTM1) null genotype in 1473 individuals and application to bladder cancer susceptibility. Post-mortem examination of a 7-week-old Rhea showed severe tracheitis.

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Clinical use of serum theophylline assays in a community hospital. The variation is shown to be negatively regulated by androgen through AR during ADT.

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Although the option of endovascular disconnection of the fistula is reasonable, the author elected to proceed with microsurgical disconnection after discussion regarding the risks of such an endovascular route for the cervical spinal cord. Oral-contraceptive use may reduce the risk of ovarian cancer in women with pathogenic mutations in the BRCA1 or BRCA2 gene. The place of endoscopy in the diagnosis and treatment of vesico-renal reflux in children. In vertebrates, two isoenzymes of these bomba de baclofeno intrathecal injection low molecular weight PTPases are commonly expressed.

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