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Topirol (Topiramate)

Topirol is the brand name of Topirol, an anticonvulsant drug used to prevent seizures and reduce the frequency of migraines. While its exact mechanism of action is unknown, studies suggest Topirol might alter the production or action of neurotransmitters in the brain, suppressing the abnormal activity of the nerves in the brain that cause seizures or preventing the abnormal activity from spreading to other nerves. Other research has suggested that it might suppress the nerves directly, thereby making them less likely to fire. The Food and Drug Administration (FDA) approved Topirol to treat seizures in 1996.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

Similar Products:
Uprox, Ranvir, Hytrin, Nobactam, Cytoxan, Aldactazide, Reduprost, Gabantin, Sulotrim, Sinersul, Galepsi, Florazole, Spirolon, Warfarina, Alizar, Globel, Omeprol, Lovire, Sulfametoxazol, Amoxival, Tambac, Lyflex, Lansopral, Tidact, Vandral, Altacef, Azitrocin, Danoxilin, Asiviral, Clavinex, Talavir, Topiramate, Cefzone, Cifran, Trichex, Omeprazolum, Meprazol, Claromycin, Fexofenadine, Nemasole, Suhagra, Clarithromycin, Omezolan, Aciclostad, Duloxetina, Somac, Apcalis, Starpod, Osiren, Primazol,

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Ambulatory electrocardiography is increasingly used as a noninvasive diagnostic cardiologic test to detect symptomatic or silent myocardial ischaemia. However, the significance of quantitative changes in the nucleolar components is unknown.

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Although system performance remains to be improved for clinical use, expected advances in camera technology as well as consideration of respiratory motion and automation of the individual steps will make this approach an interesting alternative for guiding percutaneous needle insertions. The method works by initially aligning the framework sequences of K1 VH and VL with those of other scFvs that are stable and give a good yield as immunotoxins. The results for Vigna defied the predictions of the assay for either homogeneous or heterogeneous model. Frequency-dependent potentiation of voltage-activated responses only in the intact neurohypophysis of the rat.

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Histological examination revealed four agents not previously identified. Surgery was performed in five patients with tumors following localization by CT only. We recently reported the first isolation of a tetracycline-resistant Chlamydia trachomatis strain in Toulouse from a woman treated with tetracycline. Cell-mediated inhibition of proliferation and activation of alloreactive cytotoxic lymphocytes: maintenance of response potential of precursors and dissociation between proliferation and effector function of activated cytotoxic lymphocytes.

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In intact rats infused with leptin (0.31 micromol/day), the expression of uncoupling protein-1 messenger RNA in interscapular brown adipose tissue was increased, whereas no such effect of leptin on the uncoupling protein-1 messenger RNA expression was observed in brown adipose tissue in chemically sympathectomized rats. Satisfaction and distress in a community: a test of the effects of life events.

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In total, 26 proteins associated with CD4 were identified on CEM cells. A new method for the extraction of DNA from Ascaris suum muscle has been developed. The effect of betel nut extracts on dehydrogenase activity of Streptococcus mutans GS 5. This study had the objective of estimating the costs to the public and private healthcare systems and to families of tuberculosis treatment and prevention.

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Hair follicle melanocyte precursors are awoken by ultraviolet radiation via a cell extrinsic mechanism. Two groups of children were given the Child Manifest Anxiety Scale to measure their general anxiety and the Venham Picture Scale to assess their dental anxiety. Comparative trials have demonstrated that four currently available oral agents can lower blood pressure rapidly and predictably.

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Percutaneous endoscopic gastrostomy: Naval Hospital Bethesda experience. Modulation of acetylcholine release by D1, D2 dopamine receptors in rat striatum under freely moving conditions.

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The elderly need to be incorporated into health programs and policy. A combined physical and genetic map of the cyanobacterium Synechocystis sp. Isolation of cholesterol esterase from the pancreatic juice of dogs The data were further analyzed to investigate the interrelation between such parameters as the age-distribution of patients by diseases of the respiratory system, sex and types of infection and the species and frequency of isolation of the organisms, and also the relationship between the antimicrobial chemotherapy prior to collection of clinical specimens and the species and incidence of the bacterial isolates.

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Serological profile in so-called seronegative rheumatoid arthritis Antibodies against different viral proteins have been shown to appear 8 days postinfection and to circulate for more than 2 months in case of acute TBE. Good mechanical strength and continuity of the new bone and good zygomatic asymmetry were achieved in each patient.

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The apparent density of sperm cells may be of importance in sperm physiology. Thus receptors connected to vagal C fibers are present throughout both atria and are activated by moderate changes in pressure. It is concluded that this test, if carried out under the controlled conditions described, is sufficiently reproducible between laboratories and repeatable within laboratories to be used as a standard test.

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These results indicate increased bone turnover in hypercholesterolemic or dyslipidemic patients regardless of gender, and suggest the importance of treating hypercholesterolemia or dyslipidemia in order to prevent not only arteriosclerotic complications but also osteoporotic bone loss and subsequent fractures. The rather characteristic appearance of herniated liver on the nuclear liver/spleen scan is noted and its use rather than pneumoperitoneum is recommended. Workshop I--Fifth Joint National Committee report: how should it differ from the 1988 report? Inverse Monte Carlo (IMOC) is a unified reconstruction algorithm for single photon emission computed tomography (SPECT) that provides simultaneous compensation for attenuation and collimator divergence. Patients who became seizure-free had an earlier age at first risk than did those with persistent seizures, and tumor presence weakly correlated with postoperative outcome.

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Discriminative uptake of metals by the liver and its relation to induction of metallothionein by cadmium, copper and zinc. This might help interpretation of the characteristic species variation in susceptibility to NTE inhibitors which are known to be potent delayed neurotoxic agents. Several experimental results published in the literature showed that weak pulsed magnetic fields affected the response of the central nervous system. All adjacent intervertebral discs showed a decrease of signal intensity on the T2-weighted MRI.

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Interferon did not affect cell growth appreciably but stimulated CEA release into the medium during the first three days of culture. Surgical indications, technic and results of 128 cervical cerclage operations Intestinal manipulation results in two distinct phenomena: local intestinal inflammation and a decrease in splenic cellularity. A series of 6 patients with ureteral metastases from breast carcinoma treated by radiation therapy has been evaluated.

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Primary hydatid cyst of peritoneum presented as abdominal lump: a rare presentation. Importance of pyrimidine nucleotide salvage pathways for DNA synthesis in skin.

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This technique also permits further characterization of regions of decreased activity. The data demonstrate that aspirin prevents early hyperfiltration and prevents the fall in GFR and glomerular basement membrane thickening that occurs over time in diabetic rats. Triplex real-time PCR--an improved method to detect a wide spectrum of mitochondrial DNA deletions in single cells. Chemotherapy-related amenorrhea after adjuvant paclitaxel-trastuzumab (APT trial).

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Furthermore, our data suggest that HuR level could be regulated by miR519. rhTBP-1 might possibly bind TNF-alpha and reduce the downstream phosphorylation of two main effectors of the neuroinflammatory response, p38MAPK and JNK. Its Km toward the chromogenic substrate was 0.35 mM, which agreed well with the published value for plasmin. The Trade Union Clinic is situated centrally in the large industrial area west of Melbourne. Neither patient had an acute neurologic insult other than nonconvulsive SE (NCSE) accounting for s-NSE changes.

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Insulin appears to contribute to the fall in blood pressure, as bolus injections of insulin (even before ensuing hypoglycaemia), or insulin infusions (with an euglycaemic clamp), when given intravenously lower blood pressure. Synovial oxygen partial pressure after experimental microtraumatic joint affection. The DPP4 activity, active GLP-1, and glucagon were measured at baseline and 4 years later.

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It explores the attitude of therapists to the role of student supervisor and their level of preparedness. Comparative characteristics of the biophysical properties of influenza A, B and C proteins The probable functional significance of these differences is discussed.

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Permeable barriers are used for passive remediation of groundwater and can be constructed from a range of materials. To perform a systematic review of evidence about decision aids and other exportable tools that promote shared decision making in serious illness, thereby (1) identifying tools relevant to the treatment decisions of seriously ill patients and their caregivers, (2) evaluating the quality of evidence for these tools, and (3) summarizing their effect on outcomes and accessibility for clinicians. Interrelationship of neutrophilic granulocytes, endotheliocytes and mononuclear macrophages in occurrence and course of purulent-septic states. Conditions for the equivalence of continuous to pulsed low dose rate brachytherapy. The optimal treatment beyond fulvestrant has not been established.

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Genomic organization of DHR38 gene in Drosophila: presence of Alu-like repeat in a translated exon and expression during embryonic development. Reciprocal expression of pleiotrophin and midkine in normal versus malignant lung tissues.

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Clinical signification of natural killer activity in B-cell chronic lymphocytic leukemia. The distribution of tyrosine hydroxylase-, substance P- and enkephalin-immunoreactive neurons in the cat dorsolateral pons was studied using the indirect immunofluorescence method of Coons. Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor. Serum parathyroid hormone-related protein concentrations in patients with hematologic malignancies or solid tumors. In the anencephalics, alterations located within the body of the sphenoid bone led to a reduced cranial floor angle and a more vertical clivus.

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We have already demonstrated the presence of abnormal heme pigments in clinical cases of shock using scanning spectrophotometry (3). Increased excretion may be a factor in this activity, however, it cannot account for the total effect. As the country moves to a managed care environment potential partnerships with SBCs represent a unique opportunity to improve the delivery of care to adolescents, assuring increased access to a package of health services that they need. This report describes a reproducible and characteristic sequelae for radiation cataractogenesis in the amphibian. Carotenoids have two major functions in bacterial photosynthesis, photoprotection and accessory light harvesting.

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The remaining sugars were distributed in various ratios between the protein and lipid fractions. Gluteal Tendinopathy: A Review of Mechanisms, Assessment and Management. In severe pancreatic anastomotic leakage, it is better to intervene surgically as soon as possible by debridement of the distal part of the pancreas and ligation of the stump with nonabsorbable suture.

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We suggest that smaller doses of MTX may be given and treatment costs thereby reduced if probenecid is given in addition. Results suggested that when bone resorption ceased, Ca absorption was regulated by homoeostatic mechanisms at a level just sufficient to maintain maximum retention, and that the maximum rates of absorption measured may not have been true maximum rates. We performed frozen-section analysis of blood aspirated from a pulmonary artery catheter in a trauma victim with fat embolism syndrome and found marked levels of pulmonary microvascular blood fat.

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An hypothesis is presented in which all the genes of living organisms are proposed to arise from the juxtaposition of the genes from different elementary organisms. Pathologically, a small vessel vasculopathy involving arterioles and capillaries as well as venules in both gray and white matter is the earliest and most consistent change.

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Ontogeny of the corticoliberin neuroglandular system in rat brain. With other cell lines the molecular weights and subunit composition varies, but the major component is always of MW 125-140 kD.

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Digital retinal imaging using store-and-forward technology is used to screen for diabetic retinopathy (DR). The influence of bile salts and bile lipoprotein complex on pancreatic lipase hydrolysis of monomolecular films. Pharmacologic heart rate control during the LIMA-LAD anastomosis is not critical with the use of a surgical retractor which diminishes ventricular motion.

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Efficacy and safety of the direct renin inhibitor aliskiren and ramipril alone or in combination in patients with diabetes and hypertension. Information content of multispectral lidar measurements with respect to the aerosol size distribution.

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Microcystic adnexal carcinoma--a case report and review of the literature. To determine the incidence and risk factors for rash in Thai patients taking four different non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimens. Kinetics of methotrexate binding to dihydrofolate reductase from Neisseria gonorrhoeae.

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A stable dynamic joint is provided with the stapes capitulum (ossicle cup). All children with ventriculo-coronary arterial communications had perfusion defects both in the ventricular septum and in the left ventricular free wall. The assessment of the role of psychogenous factors in both varieties of allergic rhinitis was the main purpose of the investigation.

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Ethnic distribution of the glutathione transferase Mu 1-1 (GSTM1) null genotype in 1473 individuals and application to bladder cancer susceptibility. Post-mortem examination of a 7-week-old Rhea showed severe tracheitis.

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Clinical use of serum theophylline assays in a community hospital. The variation is shown to be negatively regulated by androgen through AR during ADT.

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We report the case of an unusual and early neonatal renal venous thrombosis. However, all systems devised to date have had undesirable photographic aberrations. Results show that volume measurements in adenovirus-infected spheroids are confounded by the cytopathic effect occurring in infected cells.

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beta-Amyloid precursor protein fragments and lysosomal dense bodies are found in rat brain neurons after ventricular infusion of leupeptin. Visual prognosis appears to be good, with most patients retaining visual acuity of 20/80 or better. The urethral pressure profile studied in 10 patients showed reduction in most and the peak value in all the patients. Strategies for primary prevention exomax vs matrix movie of non-insulin dependent diabetes mellitus. Bombesin may prove to be an important enterotrophic factor for gut mucosal proliferation.

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Although the option of endovascular disconnection of the fistula is reasonable, the author elected to proceed with microsurgical disconnection after discussion regarding the risks of such an endovascular route for the cervical spinal cord. Oral-contraceptive use may reduce the risk of ovarian cancer in women with pathogenic mutations in the BRCA1 or BRCA2 gene. The place of endoscopy in the diagnosis and treatment of vesico-renal reflux in children. In vertebrates, two isoenzymes of these bomba de baclofeno intrathecal injection low molecular weight PTPases are commonly expressed.

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NBT test in the differential diagnosis of viral hepatitis and obstructive jaundice In 39 patients cefspan cefixime capsule 100mg with breast cancer and in 38 female controls the leucocyte adherence was tested in glass tubes in the presence of a series of extracts of breast cancer and control tissues. The results demonstrate the usefulness of adaptive mesh refinement and the significance of adopting anisotropic material modelling in the context of tissue/prosthesis interaction. The data strongly suggest that CsA has an inhibitory influence on essential basic processes in T cells.

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