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Synthesis of steroidal D-ring fused pyrazolines: study of regiochemistry of addition. The aim of the present article is to give an overview of the current biomechanical and clinical studies that focus on how to increase the stability of locking plate fixation of proximal humerus fractures. Intrapulmonary stenoses and lung segments perfused exclusively by large systemicopulmonary collaterals made corrective surgery impossible in the other 5 children.

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Massive pulmonary embolism remains a clinical challenge where rapid diagnosis and appropriate therapy have a critical impact on patient outcome. We also used multivariable multinomial logistic regression to analyze the factors associated with care seeking by type of obstetric complication (eclampsia, sepsis, hemorrhage, and obstructed labor).

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In in vitro studies using isolated pieces of rat antrum, isoproterenol stimulated acute phase release of gastrin, whereas phenylephrine was again without effect. Determination of illicit and/or abused drugs and compounds of forensic interest in biosamples by capillary electrophoretic/electrokinetic methods. Larval and adult eye of the western rock lobster (Panulirus longipes). Antibodies raised against the RGD site in thrombin specifically recognized thrombin digested with plasmin, but were unable to interact with native thrombin or prothrombin and inhibited potently B16-BL6 melanoma cell adhesion. High-performance liquid chromatographic determination of netilmicin in guinea-pig and human serum by fluorodinitrobenzene derivatization with spectrophotometric detection.

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The amount of its components increases when cetylpyridinium chloride is introduced into the fixative, and it appears intensely stained by ruthenium red and alcian blue at low concentrations of MgCl2. The production of single-strand breaks in DNA of mammalian cells incubated in dilute suspension with misonidazole (15 mM) under hypoxic conditions is greatly decreased by the presence of TAN (10 mM).

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Abbreviated exposure to hypoxia is sufficient to induce CNS dysmyelination, modulate spinal motor neuron composition, and impair motor development in neonatal mice. Glucocorticoids inhibit somatostatin gene expression through accelerated degradation of somatostatin messenger ribonucleic acid in human thyroid medullary carcinoma (TT) cells.

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A focus group of patients and caregivers was convened to describe their expectations of self-care technology. Hence, amplicon sequencing can potentially be used to identify hot spot mutations in colorectal cancer metastases in frozen and FFPE tissue. Current analgesics have drawbacks such as delays in acquisition, lag-times for effect, and side effects. Sixty-five stable coronary artery disease patients (49-57 years old), 30 unstable coronary artery disease patients (49-58 years old), and 32 non-coronary artery disease patients (49--57 years old) who were matched for age, sex, smoking habits, hypertension and diabetes were enrolled in this study. The purpose of this study is to evaluate the relationship of BMP-2 with atherosclerosis and calcification in patients with T2DM.

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Patients with MBC who failed to respond to previous taxane-based treatments were recruited. Current cancer chemotherapeutic drugs have limited efficacy due to the fact that tumour cells are a rapidly changing target characterised by genomic instability. Cloning, sequencing and expression of a novel homeobox gene AxNox-1 from the Mexican axolotl. Osteoblastoma of the jaws: current concepts and differential diagnosis. 8 of 12 rats from whom the IUD had been removed on Day 2 showed evidence of implantation.

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Calves challenge exposed with virus 3, 7, 11, 15, or 19 days after vaccination and challenge exposed 4 days later with Pasteurella haemolytica did not develop viral-bacterial pneumonia, whereas 2 of 3 control calves died of fibrinous bronchopneumonia 40 and 60 hours after the bacterial aerosol and the 3rd control calf had similar lesions. One group was preschool children (average age of 5.1 years), two groups were primary school children (7.7 and 9.8 years old respectively) and the final group was comprised of adults. Atrioventricular junction ablation (AVJA) is a highly effective treatment in patients with therapy refractory atrial fibrillation (AF) but renders the patient pacemaker dependent.

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The corticosterone and anti-KLH IgG antibody responses to morphine were measured. Following intravenous administration of physostigmine salicylate for tricyclic antidepressant poisoning in 21 patients, convulsions occurred in two patients, and severe cholinergic manifestations occurred in two others. A history of recent zoster dermatitis should be sought in patients with ARN. The average angle produced by the first principal axes of the scaphoid and lunate was 23.6 degrees, scaphoid and capitate was 73.2 degrees, and the capitate and the lunate was 93.5 degrees. A systematic review was performed according to the guidelines of the Cochrane Collaboration.

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The lines in NMR spectrum of 1H and 19F representing individual fragments of ftorafur molecule were shown to be broadened in the presence of BSA and DNA. Nordihydroguaiaretic acid (a potent 5-lipoxygenase inhibitor) also exerted a strong and concentration-dependent inhibition of 5-HETE and leukotriene B4 and C4 formation with IC50 values of 0.15, 0.09, and 0.1 microM, respectively. Papers from the First International Course on Occupational Neurology. The dilated vein of Galen, straight sinus and torcular were clearly seen.

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By adding catalase, concentrations up to 2000 mg/dl are detectable. Collectively, our observations suggest that a previously uncharacterized timing mechanism activates new degradative pathways at the onset of gastrulation, which could play an essential role in releasing cells from maternal programming.

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The nine surgical survivors are in good general condition with maximum follow-up of 7 years. The present study was undertaken to investigate whether inhibition of ovulation, which is known to occur after treatment with progesterone antagonists, is due to the effect of high levels of prolactin. This fixed particle hypothesis continues to serve to as the foundation for urolithiasis research today. Effects of nifedipine on pulmonary arterial hypertension in patients with respiratory insufficiency without acute failure.

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The strains were divided into two groups on the basis of wall composition. Regulation of intracellular pH in subpopulations of cells derived from spheroids and solid tumours. These findings implicate alterations in host defense, cell-to-cell adhesion, and aging and senescence in the pathophysiology of pulmonary fibrosis. An aqueous two-phase system, consisting of PEG 600, potassium phosphate and water was successfully applied as liquid-liquid two-phase system in CPC.

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Dermatomyositis with pericardial tamponade and polymyositis with pericardial effusion. Mucosal fluorescence was confined to the base of the crypts of Lieberkuhn, where Paneth cells are located. Proposals by the French-American-British Cooperative Leukaemia Group. Theoretical considerations of eye design allow us to find routes along which the optical structures of eyes may have evolved.

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A homogeneous receptor-ligand assay based on fluorescence resonance energy transfer is described. Ex-vivo treatment of AVM tissues: Intact AVM tissues were treated with doxycycline for 48 hours. Quantitatively, the urinary excretion of 14C-2-chlorobenzyl alcohol following cutaneous application differed substantially from that after the systemic administration. To identify the regulatory gene directly or indirectly involved in CIRCE-mediated heat-inducible groE expression, B.

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Mineral homeostasis in neonates of streptozotocin-induced noninsulin-dependent diabetic rats and in their mothers during pregnancy and lactation. All masses contained additional stellate or cleftlike low-density zones, and two contained calcification. The objective was to investigate, in twelve normal subjects, how head, shoulder, hip and knee movements and torques induced towards the support surface were affected by vibratory proprioceptive and galvanic vestibular stimulation, and to investigate whether movement pattern, body posture and movement coordination were changed over time. Schwartz-Matsuo syndrome in retinal detachment with tears of the nonpigmented epithelium of the ciliary body.

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This post-translational assay has permitted the investigation of the subcellular localization of the enzyme. This article will focus on the differences in lung histology and morphology, respiratory mechanics, and response to ventilatory strategies and pharmacologic therapies in pulmonary and extrapulmonary acute respiratory distress syndrome. A construct of IL-2 and pseudomonas exotoxin (PE40) has been genetically engineered.

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Essential changes have been established in the auditory and vestibular analyzer of the workers from both productions. In addition, longitudino-frontal sections through the dorsal regions revealed repetitive arrangements of substance P-like-immunoreactive fibres along the whole spinal cord. After a normal number of proneuromasts is initially deposited by the migrating primordia, interneuromast cells divide and differentiate to form the extra neuromasts.

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Power of the affected-sib-pair method to defect disease susceptibility loci of small effect: an application to multiple sclerosis. Detection limits are 5-7 micrograms aflatoxin B1 and 20 micrograms ochratoxin A/kg. Recombinant human interleukin-1 beta (rhIL-1 beta) is shown to be a strong inducer of Fc receptors (FcR) on murine macrophages and not on granulocytes.

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beta-Xylosidase from Aspergillus niger 15: purification and properties. The method uses standard amino acid ion exchange chromatography followed by reverse phase high performance liquid chromatography after derivatisation of GL to a fluorescent product. Specimens were fabricated by bisecting cylindrical quartz glass hollow tubes. Serum anticholinergicity was significantly correlated with nortriptyline but not with paroxetine plasma levels.

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Personality characteristics related to treatment decisions among inpatient alcoholics: a non-relationship. It has been suggested that immune complex deposition may be responsible for such changes. Hemorrhagic macular choroidopathy can also be distinguished from choroiditis associated with hemorrhages.

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Intranasal infection with CPV induced severe peribronchial, peribronchiolar, and perivascular hemorrhage with a mixed inflammatory cell infiltrate, bronchial and bronchiolar epithelial cell hyperplasia with intracytoplasmic acidophilic inclusion bodies, and alveolar hemorrhage and edema. Application of optical coherence tomography in non-invasive characterization of skin vascular lesions.

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A systems biology approach for defining the molecular framework of the hematopoietic stem cell niche. PET/CT is highly accurate in diagnosing patients suffering from HNSCC. A method and results of using optic penalization in preschoolers with amblyopia and unilateral strabismus

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Sections 1.5 mm thick were removed from the coronal and the axial plans without sedation (mean age: 9, 6 years). (Multiply damaged sites may also be the biologically relevant type of damage caused by other agents, such as UVA, B and/or C light, and some antitumour antibiotics.) The quantitative data available from radiation studies of DNA are shown to support the proposed mechanisms for the production of complex damage in cellular DNA, i.e.

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Differences between Occidental and Oriental postmenopausal women in cutoff level of endometrial thickness for endometrial cancer screening by vaginal scan. A randomized, double-blind, placebo-controlled trial was conducted in 126 women who previously had not responded to outpatient therapy for hyperemesis gravidarum during the first half of pregnancy. After extraction, derivation of the drug and a structural analog internal standard is carried out with trifluoracetyl imidazole. However, we demonstrated that stimulation with IFN-gamma is capable of upregulating TLR9 expression in mDC to a level comparable with expression in pDC.

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Herpes simplex virion protein 16 (VP16) contains two strong activation regions that can independently and cooperatively activate transcription in vivo. The surgeon must be avoided by respecting a few simple precautions. In children with upper respiratory tract infection the risk of anesthesia is increased--fact or fiction? Tamoxifen has been used as an anti-estrogen for the prevention and treatment of breast cancer. From the known association of glycolytic enzymes with the I-band of muscle it is proposed that electrical stimulation of anaerobic muscle increases enzyme binding to actin filaments.

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Some properties of nuclear protein-synthesizing system of eukaryotic cells In addition, the ECG recordings showed a predominant S wave and probably a depressed S-T segment in response to either heat or cold exposure. This study aimed to develop and evaluate experimentally an implant-based registration method for measuring three-dimensional (3D) kinematics of the mandible and dental implants in the mandible based on dental cone beam computed tomography (CBCT), modified to include fluoroscopic function. Mortality data were taken from national causes of death registries and covered the ICD codes alcoholic psychosis, alcohol use disorders, alcoholic liver disease and toxic effect of alcohol. The complete gene 3 DNA sequence has been placed downstream of the PL promoter, and the endonuclease is overproduced by temperature induction at mid-log phase of Escherichia coli carrying the recombinant plasmid pTP2.

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Despite the high levels of anogenital SILs, to date, there has not been a significant increase in reported cases of invasive anogenital cancer in HIV-positive individuals. The enzyme demonstrated a single peak of activity on the former column with an apparent isoelectric point of 4.2, and in the latter it showed an apparent molecular weight of 600,000 (600K-protease). Monoclonal antibodies of both IgG and IgM isotypes could be isolated. The effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on the sensitivity to NK cell-mediated lysis of two cloned populations of K562 which exhibit marked and stable differences in their susceptibility to natural cytotoxicity has been examined. In a 51-year-old man, coronary artery bypass surgery for severe angina pectoris was followed by protracted mediastinal infection.

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The results demonstrated an increased number of T and B cells in peritoneal fluid and peripheral blood from patients with endometriosis as compared with controls. The effects of rapid injury included increases in Ppa, precapillary pulmonary vascular resistance, capillary filtration coefficient (Kfc), and lung weight. A method is described for detecting specific transcripts in crude mixtures of RNA. The ultrasound study was successfully performed in all six patients. A safe regimen for management of the catheter and indication for its removal are presented.

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A Self-Assembled Spherical Complex Displaying a Gangliosidic Glycan Cluster Capable of Interacting with Amyloidogenic Proteins. The removing of protein N-linked oligosaccharides improved the gel resolution. There were 14 men and 6 women with a mean age of 29.6 years (range 19-42 years).

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The anesthesiologic risk in ischemic heart disease (IHD) patients undergoing noncardiac surgery is determined by the duration of myocardial infarction sustained in the past, and the degree (severity) of stenocardia manifestations. Of a total of 72 lots of measles vaccine whose potency was titrated by microtechnique in two Vero cell samples (Vero IB and Vero INCQS), 25 had been produced with Moraten strain, 24 with Schwarz and 23 with Biken CAM-70. Opposing roles for dopamine D2 and D3 receptors on neurotensin mRNA expression in nucleus accumbens.

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Atherosclerosis in the pediatric age with special reference to initiation, progression and regression of atherosclerotic lesions. Host nerve fibers can, however, regenerate through such nerve allografts if the hosts are immunosuppressed.

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X-ray anatomical view points in the diagnosis of fractures of the orbital floor Pirenperone (0.01 mg/kg) potentiated the effect of both drugs, whereas haloperidol (0.01 mg/kg) had an opposite action.