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Based on the trends and the tremendous breakthroughs occurring during this decade, this article explores visions and dreams of the preferred future of cancer nursing as we march into the next millennium. Subjects generally responded faster to tactile cues than to visual cues. Most eukaryotic cells express multiple isoforms of the actin-binding protein tropomyosin that help construct a variety of cytoskeletal networks. Estimation of the degradation of endocytosed material by flow cytofluorometry using two neoglycoproteins containing different numbers of fluorescein molecules. The action potential upstrokes were simulated using the PSpice program for circuit analysis.

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Drug trafficking among African-American early adolescents: prevalence, consequences, and associated behaviors and beliefs. These findings indicate that a close relationship exists between autoimmunization against the NA1 antigen and HLA-DR2 and possibly also DRw6. An open brain biopsy showed multiple vessels containing granulomatous inflammation with giant cells.

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The purified recombinant IL-1 exhibited a pI of approximately 5.2 and a sp act of 6 X 10(6) units/mg. The structure of the capsular polysaccharide from Klebsiella type 57 has been investigated. Changes in the blood flow were greater than a degree of primary tumor spreading.

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Calcium deposits were found in the middle and deep parts of the dermis surrounded by homogeneous collagen staining positively with Alcian blue solution. Many ESD methods using traction have been developed, such as clip-with-line method, percutaneous traction method, sinker-assisted method, magnetic anchor method, external forceps method, internal-traction method, double-channel-scope method, outerroute method, double-scope method, endoscopic-surgical-platform, and robot-assisted method. Therefore we suggest that the influence of elevated CE levels on the development of atherosclerosis may be also mediated by their influence on the eicosanoid metabolism.

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The calculated M(r) from the deduced protein sequence, 5052.6, agreed with that obtained by mass spectrometry. The results revealed that the heavy metal concentrations were high in the samples collected from industrial sites as compared to non-industrial sites.

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To evaluate the etiological roles of Capnocytophaga species in the pathogenesis of periodontal disease, we examined the immunological activities of lipopolysaccharides (LPSs) from various Capnocytophaga strains. Thrombi were externally surrounded by a strip of connective tissue and beyond by endothelial cells that were occasionally continuous with the tunica intima. The mechanism of activation of kallikrein-kinin system in the plasma of patients with atopic allergic diseases Unlike female pseudohermaphrodites, the majority of male subjects with pseudohermaphroditism remain unclassified by these techniques. Here, we demonstrate that anti-MT1-MMP monoclonal antibody (mAb) impaired monocyte chemotactic protein-1 (MCP-1)-stimulated monocyte migration on fibronectin (FN), vascular cell adhesion molecule-1 (VCAM-1), and intercellular adhesion molecule-1 (ICAM-1).

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Two patients had persistently elevated calcitonin levels after six months, which predated positive DMSA (V) scans. Tissue fluid was obtained from subcutaneously implanted steel net cages and by implantation of thin cotton threads under the muscle fascia. The depressive effect was accompanied by an obvious increase in the blood pressure. Indiana is the first state to adopt air ambulance standards, although other agencies have established or are attempting to establish similar guidelines.

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The largest concentration of plasmacytic cells within avian lymphomyeloid tissue appears in the Harderian Gland (HG). To investigate fluid resuscitation affecting the result of treatment of patients with traumatic shock. aeruginosa seems to us useful to study the factors promoting localisation and multiplication of this organism in a tissue. Edentulousness in relation to remodeling of the gonial angles and incisures in dentate and edentate mandibles: morphometric study using the Image J software. This disconnection of side branches occurs exactly at the point of bifurcation.

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Is it time to replace propranolol with carvedilol for portal hypertension? Part II: Marginal bone level interpretability with Status-X and Orthopantomography Model OP 3.

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Energy and macronutrients intake from pre-packaged foods among urban residents The effect of sodium bisulphite on nicotinic cholinoceptors in the frog rectus abdominis muscle. This generic formulation and Theo-Dur are bioequivalent in children. Addition of 1 mM beta-xyloside to both early- and late-passage cultures produced a ten-fold enhancement of extracellular 35S-GAG production without a concomitant increase in surface-associated 35S-GAG.

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It could be followed or terminated by a weaker period of facilitation during relaxation of the muscle. Because of good results, Y-V plasty has entirely replaced Z plasty in the correction of contracted burn scars at my hospital. Mycological cure proportions were not statistically significant between patients treated by terbinafine or itraconazole for toenail onychomycosis. The authors review the current status of development of TRAIL-targeted therapy with an outlook towards the future.

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Multistate outbreak of human Salmonella infections associated with exposure to turtles--United States, 2007-2008. tau suggested that long distance dispersal events and human activities could play a major role in the colonization and expansion patterns of B. The endoplasmic reticulum (ER), which plays a role in apoptosis, is susceptible to oxidative stress.

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Yeast caspase (Yca1p) and cellular reactive oxygen species (ROS) are key regulators of this process. Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virus. Hydropiperside, a new sphingoglycolipid from Polygonum hydropiper. Clinical renal allograft transplantation in a Dalmatian dog: case report. Data presented herein indicate that mitochondrial membrane protein-specific antibody APO2.7 after permeabilization is a useful marker for detection of early apoptotic cells dying by premitotic and postmitotic apoptosis.

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Novel molecular targets in the treatment of cardiac hypertrophy. Kainate injury did not affect the level of rGas7-b, but the level of isoform c was substantially suppressed in the hippocampus. The excretion of human urinary kallikrein quantity and activity in normal and low renin subgroups of essential hypertension. Two of the 3 studies evaluating maternal outcomes showed that episiotomy is related to increased risk of advanced perineal tears. An evaluation of a recently published neonatal vancomycin population pharmacokinetic model in a large external dataset supported the predictive performance and generalizability of the model.

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This study confirms that telepractice systems can be designed to support fluoroscopy image transfer and highlights important considerations when developing telepractice systems for VFSS analysis to ensure high-quality radiological image reproduction. Modifying potential was scored by comparing the number and area per cm2 of induced glutathione S-transferase placental form (GST-P)-positive foci in the liver.

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An experimentally induced phlegmonous abscess by a strain of Bacteroides gingivalis in guinea pigs and mice. These results indicate that overweight and obese individuals have a lower step rate and are spending less time for moderate to vigorous PA. The spectra demonstrate that under resonance conditions, when absorption is very strong, only a very thin top layer of the sample is probed (hundreds of nanometers range).

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Plasma anaphylatoxin concentrations in inflammatory skin diseases. Beginning early in gestation, males and females show differential developmental trajectories and responses to stress.

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No evidence of flame cells, neural mass, or commissures was detected in daughter sporocysts by the methods employed. The obese phenotype was not associated with overexpression of GLUT 4 mRNA in gastrocnemius muscle.

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Likewise, to avoid overlooking CHF in elderly patients with known COPD left ventricular (LV) function should be routinely assessed. The three-dimensional (3D) structure of the reactant, a helical diphenanthrene derivative, requires going beyond constant-height imaging. Atrial pacing in a patient with a Wolff-Parkinson-White syndrome pattern showed unusual variability in AV nodal conduction time. Effect of cobalt and copper o-phenanthroline complexes on electron transport and energy coupling activity in reaction centers and chromatophores of purple bacteria Mining of expression profiling databases and analysis of patient samples reveal that CRTC2 and its target MMR genes are downregulated in specific T cell lymphoma subtypes, which are microsatellite unstable.

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The brain of a honeybee contains only 960,000 neurons and its volume represents only 1 mm3. Some risk factors associated with breast cancer may be more predictive of estrogen receptor (ER)- positive than ER-negative tumors. In this single institution phase II study, 24 chemotherapy-naive, eligible patients were entered.

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The overexpression of the MK protein might be correlated with the existence of HBV DNA in the nuclei of carcinoma tissue. The number of CD3-positive lymphocytes in the GME lesions tended to be greater than in NME, though the difference was not statistically significant. Despite the high accuracyobtainable by radiological investigation, diagnostic surgical exploration is warranted in a small proportion of patients with renal cystic lesions.

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The first Robert Furchgott lecture: from endothelium-dependent relaxation to the L-arginine:NO pathway. Association of Lhermitte-Duclos and Cowden disease: report of a new case and review of the literature. ferrooxidans appears to be influenced by the substrate being oxidized by the microorganism. In the RA patients, Clq-binding complexes appeared simultaneously or later than platelet-aggregating complexes but both tests were positive several months before RA could be diagnosed. Indiscriminate removal of axillary nodes may not be justified as it may potentially worsen the morbidity of the sentinel lymph node biopsy (SNB) procedure.

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Compared with other studies in the Tibetan Plateau and surrounding regions, trace element concentration showed gradually decreasing trend from Himalayan regions (southern Tibetan Plateau) to the TGL basin (central Tibetan Plateau), and to the LHG basin (northern Tibetan Plateau), which probably implied the significant influence of atmospheric trace element transport from south Asia to the central Tibetan Plateau. At 3 and 1 year respectively of the transplantation the patients showed no evidence of graft versus host disease and no severe infections or hemorrhagic episodes have seen. It has been reported that verapamil and atorvastatin are inhibitors of both P-glycoprotein (P-gp) and microsomal cytochrome P450 (CYP) 3A4, and verapamil is a substrate of both P-gp and CYP3A4.

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Even though we noticed urodynamics improvements in group A, which objectively supports the efficacy of TCTPNS, clinical results remained the same between the two groups. Thirty-eight patients with nonsecreting pituitary microadenomas (mean size 4.2 mm) and normal serum IGF-1 levels were studied. Substance abuse and symptoms of mental illness among HIV-positive persons in the Southeast. Exploring methods of potentially improving patient comfort and pain control in cosmetic facial surgery.

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In this article, we discuss the current burden of global surgical disease and explore some of the barriers that may be encountered in improving surgical capacity in LMICs. Histologic examination of tumor specimens disclosed bronchiolo-alveolar cell carcinoma. The total amount of Lp(a) recovered during three different extraction procedures was 5 micrograms/g wet weight in tissue free of plaque and 11.8 micrograms/g wet weight in atherosclerotic tissue.

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Microelectrode recordings and deep brain stimulation surgery--reasoned discussion? Although the possibility that calcium antagonists may retard progression of renal disease remains to be ascertained, the available evidence indicates that calcium antagonists may be used in patients with renal functional impairment without further exacerbating renal function.

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The percentages of active T cells in peripheral blood from the patients with ON were normal. There are, however, a number of ultrasonographic features of normal pregnancies that may mimic disease, and these must be recognized. The initial cuts by the two proteases were made very close to each other, and in each case resulted in a greatly reduced affinity of the VP1 fragments for virus-specific antibodies in anti-VP1 serum. Effect of recombinant human interleukin 2 in experimental murine coccidioidomycosis.

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A simple method of estimating fetal absorbed dose from common abdominal and pelvic radiographic examinations is presented. Instead, oxygen is reduced by the successive transfer of single electrons, necessarily leading to intermediates with odd electrons.

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New cell lines of gastric and pancreatic cancer: distinct morphology, growth characteristics, expression of epithelial and immunoregulatory antigens. Recent studies have suggested that cholecystokinin may have a role in modulating the effects of the endogenous opioid system in physiological functions such as thermoregulation and pain control. The uptake of 48V in developing rat molar enamel was studied in vivo and in vitro using autoradiographic and quantitative methods. The MTD of this phase I trial using an accelerated titration design was determined to be 18.75 mg/d.

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Cytotoxicity splenocytes were identified as T lymphocytes on the basis of their sensitivity to anti-theta serum, resistance to the action of hydrocortisone and their inability to adhere to glass, as well as their pronounced specificity and their limited activity in the allogeneic system. The resulting neural crest cells are selected by their expression of cell-surface CD271 and subsequently cultured as 3D pellets in a defined differentiation medium to induce a keratocyte phenotype. Thromboxane A2, produced from the arachidonic acid released from platelet phospholipids by phospholipase A2, stimulates platelet aggregation. Significant reductions in both the mean recorded peak theophylline plasma concentrations and the mean 12-hour theophylline bioavailability were observed after the administration of effervescent activated charcoal (Medicoal) in single and multiple doses. The availability of large numbers of functionally defined cloned T cells would facilitate biochemical and molecular studies and might be a prerequisite for in vivo immunotherapy with cytotoxic lymphocytes.

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Hypertensive crisis and death associated with phencyclidine poisoning. Utilization of IgG avidity as a supplemental test prevented unnecessary intervention in IgG and IgM antibodies positive patients. In a previous study, we determined the accuracy of a Bayes estimation for the joint probability of the latent variables in a dataset, and we proved that the Bayes method is asymptotically more accurate than the maximum-likelihood method. Serum corticosterone measurement by radioimmunoassay indicated that the differences found in norepinephrine and TH mRNA were not due to differences in stress between the treatments. Affymetrix microarrays, analysed with Linear Modelling on Probe Level, were used to determine gene expression patterns at 24 hours after (the start of) treatment.

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In this connection the morphological studies of chorion and placenta biopsies in this group of patients are important and urgent. A large cross-sectional study provided an opportunity to estimate the prevalence of childhood asthma in several regions across Canada. The in vitro chemotactic response of human osteoblasts was investigated towards the following growth factors: TGF-beta, PDGFs, FGFs and IGFs. The ease with which several samples (up to 20) can be simultaneously processed and analyzed by a single operator and the very simple equipment required make this new method ideal for the antenatal diagnosis of beta 0-thalassemia and could encourage a more widespread use of prenatal diagnosis of thalassemias. One implication of this assignment is that the fibrillation of hydrophilic tau is thermodynamically driven by the entropy gained as hydrogen-bonded water is freed, as for collagen I.

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It has previously been shown that four physiological states can be distinguished: reproductively viable, metabolically active, intact and permeabilized. These findings may be the result of platelets having undergone aggregation and disaggregation within the circulation, and suggest that platelets may be involved in the pathogenesis of pre-eclampsia. Our findings indicate a close relationship between functional and anatomical dysconnectivity in patients with schizophrenia.

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The synthesis of aluminum nanoparticles (Alnp) has raised promising perspectives these past few years for applications in energetic materials. Comparison of a microtitration complement-fixation test and a tube latex agglutination test for diagnosis of Mycoplasma hyopneumoniae swine pneumonia. Glutamine synthetase in cultured whole retinas from the embryonic chick. Chemotherapy in earlier staged patients as adjuvants to definitive surgery or irradiation is underway in two trials, comparing the effects of cytoxan or estracyt as long-term therapies with no additional treatment. Evolutionary origins of vertebrate hormones: substances similar to mammalian insulins are native to unicellular eukaryotes.

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These hypocretin-producing cells are lost in people with narcolepsy, possibly due to an autoimmune attack. Changes in rat dopamine- and serotonin function in vivo after prolonged administration of the specific 5-HT uptake inhibitor, citalopram.

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Cyclosporine (CsA) is a novel immunosuppressive agent currently used clinically, to prevent rejection of solid organ allografts and to prevent graft-vs.-host disease. Endoluminal sonography of the obstructed UPJ was attempted in 46 patients and completed in 45 patients, 41 with primary and 4 with secondary obstruction.