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Is atmospheric aerosol an aerosol?--a look at sources and variability. Cytokines interact not only with membrane anchored receptors, but also with specific soluble receptors which circulate in the bloodstream. Implications are discussed, as well as possible limitations and directions for future research. Spinal transection accelerates the developmental expression of penile reflexes in male rats.

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Laminin shows significant specificity for inhibition by monosaccharides, whereas thrombospondin does not. The herpes simplex virus type 1 DNA polymerase processivity factor, UL42, does not alter the catalytic activity of the UL9 origin-binding protein but facilitates its loading onto DNA. Therapeutic efforts for human glial tumors have over the past years been redirected towards a compartmental treatment concept. Recent prospective studies have shown that, despite these problems, global quality of life scores as measured by generic questionnaires improve after surgery.

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However, in the child suffering from classical Lesch-Nyhan syndrome, erythrocyte HGPRTase activity decreases following adenine ingestion. Which is the best clinical test for diagnosing a knee meniscal injury?

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The purpose of this diagnostic study was to quantify the effect of high-dose corticosteroid treatment on hip joint cartilage degeneration in patients with systemic lupus erythematosus (SLE), with and without osteonecrosis, using magnetic resonance imaging (MRI). 124 healthy volunteers of both sexes, between 17 and 74 years of age, whose lifestyle was not modified during the study.

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The mortality rates of lifestyle-related diseases such as heart disease, stroke, and cancer becoming getting higher and higher in Japan as well as in western countries where much of the population is graying. However, both PHA and TPA added directly to the test cells caused substantial thymidine incorporation. Their rate of cooling is linearly correlated to the magnitude of N.S.T. In this study the release of two peptides each from the NH2- and the COOH-terminal regions of alpha 1-antitrypsin is demonstrated, indicating the presence of two inhibitory sites in alpha 1-antitrypsin. Comparative evaluation of sleep deprivation and sedated sleep EEGs as diagnostic aids in epilepsy.

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Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts. Addition of A and G caused an increase in both Jstrendo and Jendostr bicarbonate flux and a decrease in Jstrendo net.

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It has been implicated as an independent risk factor for cardiovascular disease and premature cardiovascular mortality for patients with type 1 and type 2 diabetes mellitus, as well as for patients with essential hypertension. Sodium hypericinate (in distilled water, in sodium phosphate buffer, or in polyethylene glycol) and several other hypericinate salts (potassium, lysine, TRIS or hexylamine) were instilled with no plasma constituents into the rat bladder. Genome resequencing indicated that all of the evolved chlorate-reducing strains replicated a large genomic region containing chlorate reduction genes. The development of degenerative spondylosis after successful operative decompression of the affected nerve root was prospectively evaluated in a comparative case series of 100 patients with a herniated lumbar nucleus pulposus.

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Other projections of the MPN suggest participation in the initiation of specific motivated behaviors. Characteristics of severe diabetic ketoacidoses occurring before and after 60 years of age.

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An inverse relationship between suppressor cell activity and the number of suppressor/cytotoxic subsets defined by the OK T8 monoclonal antibody was found. This occurs at a very early stage of disease, and correlates with the degree of albuminuria. Investigations of asthmatics and normal controls with lymphocyte transformation tests. Knockdown of fibronectin induces mitochondria-dependent apoptosis in rat mesangial cells. Northern blot analysis and in-situ hybridization suggest a specific role for these extensin-like genes in flower bud initiation on tobacco pedicel explants.

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It is conceivable, however, that it will never be possible to kill all leukemic cells with chemoradiotherapy of any form, and the graft-versus-leukemia effect may be essential. Provisional restorations: an integrated approach to periodontics and restorative dentistry. However, there are no reports comparing various retreatment using different PPIs. Recently, the cDNA of another monocyte-derived factor, interleukin 6 (IL 6), was cloned. The role of stereotactic radiosurgery in the treatment of benign intracranial lesions is well established.

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Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells. In addition to 2H, 13C and 15N, recent solid-sate 1H, 19F and 17O NMR work is discussed. Laparoscopy indicated that the gestation sac was below the level of the uterine vessels, and was thus of prognostic as well as diagnostic value. Organization of specialized first aid and emergency medical services in Moscow Furthermore, a CRH promoter containing this mutation exhibited a diminished response to forskolin.

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Many of the barriers to providing pharmaceutical care can be eliminated or diminished in this setting. The gp80 (TRPM-2, clusterin) cDNA cloned into an eucaryotic expression vector, was transfected into BHK-21 cells and stably transformed cell clones were obtained. However, the long-term impact of Maze procedure has not been clear yet. Cardiovascular responses to stimulation of cardiac receptors in the cat and their modification by changes in respiration.

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TMT treatment was accompanied by a low level of PKC down-regulation over 24 h, which was small compared with that produced by phorbol esters. Body image and sexual function in women after treatment for anal and rectal cancer. Differences between preoperative and postoperative NEI-RQL scores were examined. FT-IR imaging spectroscopy is well suited for studying dynamic processes occurring in multi-component systems. Transfection of constitutively active MEKK-1, an upstream activator of the mitogen-activated protein (MAP) kinase pathways, was used to isolate an enhancer element located between -89 and -50 bp in PAI-1 promoter that was activated by MEKK-1 and selectively blocked by the MEK1,2 inhibitor PD98059.

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Changes in the reflex excitability of spinal motor neurons in newborn infants during sleep and increases in environmental temperature Cells from peripheral tissues that exhibit high APP expression are characterized by their high membrane fusion activity. VA conduction should be expected during the junctional ectopy that accompanies slow pathway ablation, even when there is poor VA conduction during baseline ventricular pacing. Because it offers the possibility of monitoring other diseases with epidemic potential, such as dengue and influenza, it opens new prospects for infectious disease surveillance. Chylous pericardial effusion is a rare complication of cardiac surgery.

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After acidification to pH 5.0, the VLPs autocatalytically cleave at residue 570, providing an in vitro control of the cleavage. We hypothesized use of a decoupling device is a safe and effective mechanism to reduce dislodgements. Pretreatment NK activity in peripheral blood (PB) was comparable within the group of HNC patients.

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Chronic ethanol exposure increases the density of N-type calcium channels in brain. By using a model of sustained discharges of polymodal nociceptors (PMN) due to injection of a compound algogenic substance into the skin in anesthetized rats, it was found that stimulation of the sciatic nerve inhibited or facilitated at first and then inhibited the PMN sustained discharges markedly. We conclude that endothelin is a potent coronary vasoconstrictor even at a low perfusion pressure. The c-myb proto-oncogene is low to undetectable in resting T and B lymphocytes and shows a biphasic induction in both cell types after mitogenic stimulation, with a first peak at 3 hours and a second and stronger induction at 44 to 72 hours. Family members and others who must care for depressed older adults have received relatively little clinical and research attention, despite their extensive special needs and burden.

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Changes in plasma concentrations of immunoreactive ouabain in the tilapia in response to changing salinity: is ouabain a hormone in fish? Liking for the flavor CS increased only in the sucrose-sweetened condition, but intake increased significantly in both high-energy conditions. The value of routine preoperative laboratory testing in predicting postoperative complications: a multivariate analysis. Additional topics of discussion will be the importance of full receptor occupancy and known species differences in NK1 receptor ligand binding, which represent significant obstacles to utilizing standard rodent models of psychostimulant addiction for future screening of potentially efficacious NK1 antagonists.

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Retinoids enhance lectin binding to gp130, a glycoprotein of NIH-3T3 cells: correlation with cell growth and adhesion. Dot immunobinding is a useful alternative to radioimmunoassay for screening McAb to haptens. In the mammalian white matter, glycogen-derived lactate from astrocytes plays a critical role in supporting axon function using the astrocyte-neuron lactate transfer shuttle (ANLTS) system with specialized monocarboxylate transporters (MCTs). Experimental studies and the few clinical observations do not show that either CPPD or apatite consistently cause either inflammation or more rapid destruction in OA.

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Effect of dietary vitamin C on adrenal cholesteryl ester content in the guinea pig. Trocar site herniation following laparoscopic cholecystectomy and the significance of an incidental preexisting umbilical hernia. Endoscopy unit recommendations regarding aspirin use before colonoscopy.

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A vertical cephalometric analysis of the human craniofacial complex. A review of the literature revealed nine other patients who had conversion to acute leukemia in the absence of preceding radiation or cytotoxic chemotherapy. Repair and maintenance of the soma continue throughout sexual maturation, as shown by the persistence of feeding and the capacity for regenerative segment proliferation. Mice inoculated with the RFV strain of Friend virus develop an erythroleukemia that spontaneously regresses. Interleukin-4 inhibits the expression of tumour necrosis factors alpha and beta, interleukins-1 beta and -6 and interferon-gamma.

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After a mean follow-up period of 29 months 19 of the eyes had retained the same visual acuity, 18 had been free of renewed vitreous hemorrhage for 6 months, there had been no macular retinal detachments and all the anterior segments were normal. MRI findings and encouraging fluconazole treatment results of intracranial Cladosporium trichoides infection.

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Many cardiovascular and noncardiovascular parameters are thought to be determinants of left ventricular mass (LVM). Trunk angular kinematics during slip-induced backward falls and activities of daily living. The results of pars plana vitrectomy for certain pathologic entities compare favorably to results obtained in vitrectomies performed during keratoplasties.

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Over the course of the study, pony mares receiving calcium supplementation had significantly fewer changes in urinalysis variables, and significantly less microscopic renal damage. In this review we have focused on the advances madein observing the photo-induced response in bacteriorhodopsin and understanding the mechanisms of retinal-protein interactions which are still obscure. RNA prepared from rat anterior pituitaries or from prolactin-secreting pituitary tumors has been shown to direct the synthesis of a large form of prolactin in a cell-free system derived from wheat germ. The exposure of the cells to dexamethasone in a dose producing no cytotoxic effect drastically lowered cell proliferation under the effect of PHA and deteriorated the detectability of HLA-A and HLA-B antigens. Acta 468, 127--145) in terms of the fall in solute concentration described above.