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Effective combination of anticancer drug with its antidote for chemotherapy of hepatic metastasis. This was a prospective, randomized, placebo-controlled, double-blind, 1-year trial of paricalcitol, with outcomes measured at entry and 1 year later. Iloprost appears useful for the treatment of digital ulcers in systemic sclerosis and is associated with evidence of prolonged physiologic improvement although the mechanism of this effect remains unclear.

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Effect of a sputum digestant on the viabiltiy of Mycobacterium fortuitum. Parameters affecting in vitro immunization of human lymphocytes. Aplastic anemia with fetallike erythropoiesis following androgen therapy. In Saccharomyces cerevisiae, silencers flank transcriptionally repressed genes to mediate regional silencing.

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A detailed study of p53 mutations in colorectal cancer in Singapore. The stable transformation of the MCF7 cell line with the oncogene c-Jun resulted in a cell line (MCF7Jun), which displayed a change in morphology, enhanced migratory and invasive properties, and metastatic behavior. Despite their prevalence and the morbidity they cause, little is known about the immune response to this complex eukaryotic parasite. Gastrocutaneous fistula as a late complication of fast neutron therapy for carcinoma of the stomach. It is to be expected that the identification of the relevant tumor suppressor genes located on 1p and 19q will lead to more refined genetic tests for OTs.

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Here, we addressed the ability of cOA to modulate 5-HT-induced cellular actions in the CA1 neurons of the rat hippocampal slice.5-HT (0.1-100 microM) concentration dependently reduced the amplitude of the evoked field population spike (fPS), and produced a hyperpolarising shift in the resting membrane potential (Vr) and a drop in input resistance (R in). Micrognathia, temporomandibular joint changes and dental occlusion in juvenile rheumatoid arthritis of adolescents and adults. Beneficial effect of muroctasin on experimental leukopenia induced by cyclophosphamide or irradiation in mice. The study concludes that coping with HR crises in hospitals is existential for hospitals and requires increased awareness.

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Further studies are needed to determine the best method for assessment of HER2 overexpression. We performed a cross-sectional study including 581 stable, high-risk CAD patients.

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We found that the specific protein binding to E2F-REs is altered in apoptotic conditions compared to neuroprotective conditions, suggesting that the proteic constituents of the complex are likely to be modified upon apoptosis onset. It is suggested that the infiltrating lymphoid cells seen in the central nervous system for surviving rats are involved in the normally occurring self-limitation of the disease. These studies suggest that TGF-beta may play an important role in the accumulation of connective tissue seen in PSS and that the combined action of multiple growth factors may modulate the synthetic activity of human dermal fibroblasts. The exact origins of the two cases bearing pan-T marker(s) with no rearrangement of the T cell receptor gene has not yet been determined. The article describes historical premises of ergonomics development in the USSR, the present state and main direction of applied ergonomics, and its effective data.

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The literature on clubfeet is inadequate because a common method language for assessing the deformity is lacking. They are characterized by an outer zone of proliferating cells, an inner region of differentiating quiescent cells and an area of so-called necrotic cell death in their centre. The newborn rabbit AM appears to be up-regulated in its IL-1 beta production compared to the adult. coli is the most frequently used host for production of enzymes and other proteins by recombinant DNA technology. ELRA characteristics are compared with cell-based assays, and the issue of detection limits is addressed.

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CPK activity in cord blood was lower than in venous and capillary blood. One exposure processing to fabricate spiral phase plate with continuous surface.

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Parallel workflow tools to facilitate human brain MRI post-processing. The influence of specific PDE inhibitors on apoptosis in HL60 cells was studied. Occasionally, however, it may stand out clearly in certain phases of urethral muscular activity, resulting in a roentgen picture which may mimic an abnormality.

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Dynamic mechanical analysis indicated that Novus should have a greater propensity for energy/impact absorption. It is unlikely that the potential clinical benefits of intracoronary Abciximab can be related to modulation of integrin receptors. Forced expression of MBH1 down-regulates expression of Mash1 and up-regulates neurogenin2/Math4A, a member of neurogenins, in P19 cells during neuronal differentiation.

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The experiment showed no difference in healing after 56 days irrespective of the coolant used or whether the bone was cut with or without a cooling agent. Effects of antisense glial fibrillary acidic protein complementary DNA on the growth, invasion, and adhesion of human astrocytoma cells. Relation between bilayer phospholipid membrane breakdown voltage and temperature

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The coelomic epithelium, the vascular endothelium, and the prepuberal germ cells exhibited predominantly a 47,XYY karyotype. Further, we scan through illumination angles to capture lightfield datasets, which can be used to recover 3D intensity and phase images without any hardware changes.

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Cells destined to be somatic do not regain totipotency and senesce, while germ-line cells regain complete genome expression and immortality after meiosis and gamete fusions. We report that unwinding the DNA between the scissile phosphates, prior to DNA cleavage, is a key cold-sensitive step in telomere resolution. Effects of heparin and cholesterol sulfate on the activity and stability of human matrix metalloproteinase 7.

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Many of the techniques in wound management have not changed over the past century: compression remains the cornerstone of venous ulcer management. It is concluded that all the C-5 acids tested have encephalopathic activity although this is lessened by the presence of either a double bond or an oxygenated functional group. Compared with FTFI, PBS seemed to have revealed higher proportion of unsafe sex behaviors, so as to generated more reliable data. He did not attend for dental treatment until the age of 14 years, when panoramic radiography demonstrated varying degrees of arrested root development in the permanent dentition.

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The C3 fragment-coated cells showed increased sensitivity to spontaneous lymphocyte-mediated cytotoxicity. Deficiencies of NADH and succinate dehydrogenases in degenerative diseases and myopathies. The activation was transient: after reaching a maximum between 5 and 10 min, the activity declined back to low values during the next hours. The origin of the spntaneous changes of the membrane potential was investigated by measurements of the reversal potentials and membrane conductance changes.

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It is concluded that an acute increase in maternal plasma levels of bile acids does not produce important adverse effects in either the mother animal or the fetus and consequently, if bile acids should be deemed responsible for any deleterious effect observed in a preterm fetus in intrahepatic cholestasis, this should be considered as the consequence of a chronic process. Further reduction of linear endovenous energy density (LEED) used for EVLA can improve the therapy. This report describes two patients who had acute intrinsic renal failure that was triggered by indomethacin. Degenerating myoid cells and their receptors may represent autoantigens that induce an immunological cross-reaction with the receptors of skeletal muscles, giving rise to myasthenia gravis. It is a purely educational exercise and continued participation in this audit will ensure the highest standards of surgical care in Australia.

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After 2 weeks of incubation, infected cells were disrupted by freezing and thawing, and virus antigens were detected by immune adherence hemagglutination. Lack of inhibition of diamine oxidase during hydralazine therapy. The paper explicity demonstrates in real estate finance terms how the present system of private ownership of capital facilities inherently impedes providing a high quality of care. An immunohistochemical prognostic index (IHPI) was created using the arithmetic sum of the four individual immunohistochemical factors. An analysis of newspaper reports of cancer breakthroughs: hope or hype?

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The antigen is located on the inner acrosomal compartment, and is expressed during spermatogenesis on the developing acrosome of round and elongating spermatids. A solitary somatotropic dysregulation does not necessarily herald a relapse. Fast atom bombardment mass spectrometric methodologies for carbohydrate structure determination are intimately linked to classical procedures such as derivatization and hydrolysis. Headache is a common problem encountered in clinical practice, and undersea divers exhibit unique causes of headache in addition to other common primary headaches.

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In Serbia and Montenegro postexposure rabies vaccination is performed using five doses of rabies vaccine with a potency of 2.5 I.U. Our aim was to investigate the effect of lipids in the development of diabetic retinopathy.

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Removal of NO with an NO scavenger or inhibition of NO synthesis via NO synthase inhibitors or an inhibitor of nitrate reductase reduced both NO accumulation and gravitropic bending, indicating that NO synthesis was required for the gravitropic responses and that both NO synthase and nitrate reductase may contribute to the synthesis of the NO required. Safety and efficacy of various combinations of injectable anesthetics in BALB/c mice. Nonrandomized matched pair analysis of intermittent ischemic arrest versus potassium crystalloid cardioplegia during myocardial revascularization. The various factors affecting color production, such as the concentration of tetrazolium, incubation period, the type and volume of solvent, were optimized. level through a National Library of Medicine program similar to that offered to researchers by the National Institutes of Health is stressed.

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Best linear unbiased estimation and prediction under a selection model. The effect of immediate and delayed treatment with 2,3-dimercaptopropane-1-sulphonate on the distribution and toxicity of inorganic mercury in mice and in foetal and adult rats. However, they are cases that remain difficult to label precisely, especially in minor forms and we feel that these deserve hemodynamic investigations. We investigated the role played by antigen-presenting cells (APC) in the ongoing production of antibody. The 4.5 S RNA gene of Escherichia coli is essential for cell growth.

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Further characterization of interactors may involve immunoprecipitation, enzyme assays, or other techniques applicable to the specific protein. The total area of the corpus callosum was significantly related to the total and verbal IQs of the Wechsler Adult Intelligence Scale. The diagnostic x-ray combined with the presence of each contrast medium demonstrated a slight increase in SCE frequency compared to that of the controls. The majority of these higher stage patients are now able to be cured with combination chemotherapy. Preliminary reports indicate that exercise does, in fact, raise blood levels of HDL cholesterol and may thus provide some protective effect to coronary heart disease.

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Cells treated with 5 ng/ml of TPA undergo marked morphological changes, becoming flattened with nuclear enlargement and developing a grainy and often vacuolated cytoplasm. In these concentrations ETA and PPP but not indomethacin antagonized the action of PGF2alpha.

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JBP485 promotes tear and mucin secretion in ocular surface epithelia. Antibodies were raised in laying hens and isolated from the yolk of their eggs by precipitation with precooled (-20 degrees C) propane-2-ol and removing lipid material with propane-2-ol and acetone. Eye movement during eye opening was accomplished in three phases. Each sample was tested immunohistochemically, by sandwich ELISA and by ISH.

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Both the regression equation for bulimia and the one for restraint included physical self-esteem and narcissism as predictor variables. Two other groups of sex and strain matched mice (9 in each group) not subjected to physical training, were sacrificed and served as controls. Three cases of metastatic carcinoma to the pituitary gland presenting with local compression, causing field defects and nerve palsies are reported.

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Association of retrospective markers of glycemia and the use of continuous glucose monitoring in white adults with type 2 diabetes mellitus--a preliminary report. Which women seek help for alcohol problems, and which get good results? However, high doses of CP may lead to severe side effects to the gastrointestinal system. Only chromatographic methods allow reaching the necessary sensitivities.

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These include chemical mediation using liposomes and chemical enhancers or physical mechanisms such as microneedles, iontophoresis, electroporation, and ultrasound. It is proposed that the modifications that occur in behavior are based upon this same mode of action.

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All these studies confirm its constant efficacy, giving good to excellent results in 68 to 89 percent of cases. Publications were assessed for quality of evidence by working groups of the panel, and a summary of findings was presented in tables. The induction by glucocorticoids requires 1 h for the synthesis of mRNA and 5 h for the synthesis of proteins in various tissues and cells. The renal arterial and venous blood levels remained constant throughout the study period.

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In our previous work, we demonstrated that viable but nonculturable (VBNC) Vibrio cholerae O1 and O139 were converted to culturable by coculture with eukaryotic cells. Comments on neuropsychological evaluation of epilepsy surgery: are the tests sensitive enough? The effect of azoxybenzene on microsomal liver enzymes in the rat They may play an important role in inducing contact sensitivity dermatitis.

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Fifty male AIDS patients with Kaposi sarcoma and 50 matched controls were interviewed about occupation, exposure to pesticides, Vietnam service, smoking habits, etc. The cDNA library was constructed by GATEWAY recombinational cloning, enabling transfer of the library to various alternative vectors. Initially, the mortality rate was 28.5/100 000 and increased to reach a peak of 41.5/100 000 in 1940-1944. The response to nonirradiated trypanosomes appeared to be T cell independent, because the antibody titers were the same in congenitally athymic nu/nu and normal C57B1/6, and no evidence for the induction of T cell activity could be demonstrated in the infected nude mice. The National Institutes of Health-developed Patient Reported Outcomes Measurement Information System instruments may be useful tools for monitoring psychosocial functioning in clinical settings and for integrating patient and parent perspectives.

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Hospitals were classified into equal tertiles based on their revascularization ratio. Allergic alveolitis caused by P chrysogenum and P cyclopium has not been described previously. After restoration of normal cardiac activity, the operation was completed after conversion to an open approach.

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Anterior and posterior vitrectomy as a method of treating severe eye diseases The technique of brain stem auditory evoked electroencephalographic response testing was applied to 61 newborn infants in an attempt to study the potential influence of perinatal risk factors for hearing impairment and/or asphyxial brain damage. If Government plays an active role along with private sector, stem cell research in Pakistan can be boosted up. Temperament characteristics of mildly developmentally delayed infants.