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The results of the competition measurements and gel shift assays suggest that serine at the i-1 position (i is proline) can be replaced by alanine without affecting the binding properties of the motif. Monitoring of renal function in children before and after liver transplantation. Identification and purification of a protein that binds the yeast ARS consensus sequence. A continuum of specialists and generalists in empirical communities.

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Multiple paternity and population genetic structure in natural populations of the poeciliid fish, Heterandria formosa. The majority of elderly ED patients are not immunized adequately with influenza and pneumococcal vaccines as recommended by the Centers for Disease Control and Prevention. Tuberculosis continues to be a major health care problem in the world, especially among children.

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We report on current trends in robot-assisted surgical training, focus on simulation-based education, and anticipate future developments. Edentulousness did not cause remodeling of the gonial angle of the mandible or in the mandibular incisure angle. When conditions deteriorate, animals have to adapt physiologically to avoid detrimental effects to growth and survival. A 6-year-old boy with hereditary motor and sensory neuropathy (HMSN), congenital cataract and mental retardation was reported. Use of plasmapheresis and partial plasma exchange in the management of patients with cryoglobulinemia.

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Involvement of oxygen-derived free radicals in L-arginine-induced acute pancreatitis. Anti-hypertensive medicines prescribing for medical outpatients in a premier teaching hospital in Nigeria: a probable shift of paradigm. We hypothesized that animals trained with a maintenance-diet food source (chow) would demonstrate more variation in the pathways taken to the goal location than those animals trained with the highly palatable alternative. Considerable effort has been put into improving the quality of life after radical therapy for bladder cancer, though it has proved difficult to demonstrate conclusively that these aims have been achieved. We have achieved the best results with initial closed chest tube drainage followed by continuous pleural irrigation and later by Clagett procedure or open tube drainage.

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Cytogenetic analysis of bone marrow cells and spermatogonia of male mice after in vivo treatment with arsenic. Complications were evaluated according to the Clavien-Dindo classification. Antinucleosome antibodies emerged before anti-dsDNA and antihistone antibodies.

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Patients were placed in the prone position on a couch with a leg pillow. Topical calcineurin inhibitors (TCIs) are widely used as an alternative to topical corticosteroids (TCSs) in treating of atopic dermatitis, but their risk versus benefit compared with TCSs remains unclear. In no case do the derivative curves of the concentration profiles exhibit more than bimodality in these systems and in some cases are found to exist as a single, almost symmetric, peak. Cotransfection of RXR alpha with the RARs changed the ability of the retinoids to activate transcription. The ability of directionally selective (DS) retinal ganglion cells to respond selectively to stimulus motion in one direction is a classic unresolved example of computation in a local neural circuit.

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We assessed peripheral blood mononuclear cells mitochondrial DNA (mtDNA) content and mitochondrial respiratory chain (MRC) function at baseline and at 24 weeks of follow-up. These differences are present in unstimulated cell populations and may represent a manifestation of the Lps gene.

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The authors come to a conclusion that indirect lymphography is an effective method for the diagnosis of alterations in the thyroid gland (thyroiditis, malignant tumor, diffuse and nodular goiter). Protein kinase C activity and protein phosphorylation in mouse sperm. In the immune-compromised host this common organism can rapidly become fatal even if recognized and treated appropriately.

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Human C1q: rapid isolation and quantitative determination by immunodiffusion. Phylogenetic distances, relative to the Galapagos marine iguana. When monocytes from normals were cocultured with autologous T lymphocytes with a ratio of 1:1 and stimulated with phytohemagglutinin (PHA), 3H-thymidine incorporation by T lymphocytes was suppressed. The highest glycerol value was 1187micromol/l cerebral and 2997micromol/l in the subcutaneous tissue. Ophthalmic drops contain both an active compound and many adjuvants used to stabilize the drug.

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The 8 bp long stem of these sequences adopts a B-form helix whereas the five base long single-stranded loop appears to be flexible and cannot be represented by a unique static conformation. duodecimcostatus) pine voles are two recently separated sister species with fossorial lifestyles whose different ecological, physiological and morphological phenotypes reflect the better adaptation of M. The anatomy of the area, clinical findings, operative details, surgicopathological observations and postoperative results are described.

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In this study we identified predictors for high-quality guidelines in oncology. The similarity between the observed layer line spacings of the H4 fibers and the spacings of the maxima in x-ray diffraction patterns from whole chromatin suggests that the H4 fibers have a structure related to that of chromatin. Understanding their growth may reveal insights to pathogenesis and potential treatment. On the basis of these and previous findings, we propose NO-GC1 as the major NO receptor which transduces the NO signal into cGMP at presynaptic terminals of different neuronal subtypes in the hippocampal CA1 region.

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Medial temporal lobe atrophy in patients with refractory temporal lobe epilepsy. Diagnostic features, clinical grading system, therapy and prevention are reviewed. NLCPQ-1 is a novel, weak, DNA-affinic bioreductive compound with enhanced chemosensitizing ability for commonly used chemotherapeutic agents, both in vitro and in vivo.

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Overall, ecosystem C fluxes in the studied ecosystem are highly sensitive to nitrogen deposition, but less sensitive to increased precipitation. Primary malignant gliomas from 63 patients were analyzed to determine the relationship between amplification of the gene encoding the epidermal growth factor receptor (EGFR) and expression of the corresponding mRNA. Sixty-eight patients underwent elective colon resection and intraperitoneal anastomosis with the biofragmentable anastomosis ring (BAR). The full bladder examination and the cough test to confirm urine leakage and correction of the leakage by bladder neck support (Bonney test) and urethral support are recommended in the investigation of female urinary incontinence, The Q-tip test is not recommended to measure urethral hypermobility.

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Histopathologic changes in the eye specimens in patients with chronic granulomatous disease included multiple foci of granulomatous inflammation of choroid and sclera. We describe the extraction of an infected cardiac resynchronization therapy-defibrillator (CRT-D) in a patient with a tunneled implantable cardioverter defibrillator (ICD) lead implanted from the right jugular vein. Identification of anti-centromere antibody and its clinical evaluation Cross-presentation of peripheral self-Ags by dendritic cells (DC) can induce deletion of autoreactive CTL by a mechanism termed cross-tolerance.

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The energy imparted from cephalometric radiography can be reduced to about 10 percent with the use of an improved examination technique, leaving panoramic tomography responsible for contributing about 80 percent of the total energy imparted. In most cases, the patient presents a right otalgia and pain in the area of V3. However, IRESs present in the genome of different RNA viruses perform the same function despite lacking conservation of primary sequence and secondary RNA structure, and differing in host factor requirement to recruit the translation machinery. Eastern gray squirrels may be suitable indicators for virus amplification and for risk of human spillover on a local scale in urban settings.

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We prove that the extended hydrodynamics is fully autonomous in the sense that it is compatible with thermodynamics (i.e., the entropy does not decrease during the time evolution) and with mechanics (i.e., the part of the time evolution that leaves the entropy unchanged is Hamiltonian). The importance of these laboratories is reflected in the fact that several new laboratories have recently been constructed at considerable expense and older facilities have undergone major renovations.

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A strong pelvic floor is associated with higher rates of sexual activity as well as higher sexual function scores on the condition impact domain of the PISQ-IR and the orgasm domain of the FSFI. Autoradiographic localization of T4 antigen, the HIV receptor, in human brain.

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Menstrual cycle irregularity was significantly and positively associated with the socioemotional trait of submission. The conditions for induction of B-cell inducing factor (BIF) by human peripheral blood T cells was investigated. However, transgenic animal models have demonstrated that AML-specific translocations/inversions alone are insufficient to cause overt leukemia, which occurs only when point mutations affecting receptor tyrosine kinases (RTKs) develop.

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Rapid turbidimetric determination of serum C3c and C4 by end point centrifugal analysis. Inhibition of ovulation in these animals is accompanied with an increased part of hyperpolarized ova, appearance of some signs of degeneration in the group of depolarized oocytes and absence of oocytes with polarized membrane at the metaphase I stage. The inhibition was not reversed by intradermally injected prostaglandin E2 (PGE2) in doses up to 50 ng/site, suggesting that PGE2 also may not be an important mediator. This investigation indicated that the level of histamine release induced by RATIg was dependent upon the concentration of RATIg with concentrations of 350 mcg/ml inducing optimal release.

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In the present study urinary 6-hydroxymethylpterin levels have been measured as an index of disease status in acute myeloblastic leukemic patients on antileukemic drugs. Novel Guanidinium-Based Ionic Liquids for Highly Efficient SO2 Capture.

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Significantly higher levels of metabolites were observed in patients with spina bifida, representing a state of nerve ischemia, anaerobic metabolism, and disruption of neuronal membrane. Expression of the nm23-2/NDP kinase alpha gene in rat mammary and oral carcinoma cells of varying metastatic potential. In fact, adrenal gland microvillar channel formation is regulated by adrenocorticotropin hormone and requires SR-BI expression.

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In conclusion it can be said that, once reliable reference values have been identified using a urinary cross-link assay (in particular for LP), it is possible to evaluate bone resorption in postmenopausal women. Membrane attachment of AL-1 appears necessary for receptor activation, since REK7 on cortical neurons is efficiently activated by transfected cells expressing GPI-linked AL-1, but not by soluble AL-1. The cytoplasmic tail of HIV-1 gp160 contains regions that associate with cellular membranes. A review of the presentation, preoperative assessment, intraoperative management and outcome of each case of unsuspected cecoureterocele suggests that optimal surgical management of the cecocele itself does not require total removal.

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L-arginine/NO pathway has a role in the hepatic IR because the pretreatment with L-arginine partially had attenuated the hepatocellular damage induced by hepatic IR in rats. In addition to quantitating tumor cell invasion, these methods also allow recovery of invasive cells for comparison with noninvasive cells. These results suggest that furosine, like HbA1, may become an indicator of long-term blood glucose control in diabetic patients and be useful in investigating diabetic complications on the level of tissue. However, patients and their physicians should be aware of the high surgical complication rate in elderly recipients, particularly when receiving elderly donor kidneys. We have recently reported that some liberated signal peptides are further processed by the intramembrane-cleaving aspartic protease signal peptide peptidase.

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The paper provides a short introduction to wavelets and discusses their main applications in microscopy and biological imaging. In order to become fully competent at fertilizing the oocyte, spermatozoa must undergo the maturational process of capacitation during their journey in the female reproductive tract. Circadian rhythm and proliferation of lung alveolar wall cells during postnatal growth in mice.

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Carotenoids are bioactive compounds with remarkably special properties produced by plants in response to internal and external stresses. Aggregation started 45--60 min after the addition of glucose or sucrose whereas slowly metabolized sugars as galactose and lactose required several hours to cause aggregation.

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Sonography should be used as primary investigation to detect morphological changes in chronic renal failure. This clastogenic substance could not be detected in serum of NZB line. Less cardiotoxic chemosensitizers are needed to reverse multidrug resistance in cancer.

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Other forms of management are discussed and the advantages and disadvantages of each method are presented. The study protocol was developed by a multidisciplinary team consisting of experts from the Galician HTA Agency (avalia-t), interventional cardiologists and cardiac surgeons. Fertilization in Caenorhabditis elegans requires functional SPE-9 protein in sperm. The stabilized gliding knee prosthesis has been designed as a compromise between the restrained hinged joints and the unconnected surface prostheses.

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Biocides in sewage sludge: quantitative determination in some Swiss wastewater treatment plants. Bacteriological and virological studies on the cause of sporadic acute gastroenteritis in Tama, Tokyo (1991-1996) For the strains tested, the results showed clear differences for attenuated and virulent strains, and the model was a reliable indication of virulence for humans. In vitro primary sensitization of human peripheral blood T-cells to hemocyanins was detected during a 12-14 day culture period with antigen (KLH or HCH)-pulsed macrophages. Given that several genetically obese rodents characterized by hyperphagia, hyperinsulinemia, and insulin resistance have increased hypothalamic neuropeptide Y (NPY) mRNA and peptide content, the impact of NPY administered intracerebroventricularly (i.c.v.) for 7 days to normal, awake rats was investigated.

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Gene conversion between murine class II major histocompatibility complex loci. The natural history of focal segmental glomerulosclerosis with and without mesangial hypercellularity in children. H-Y antigen could not be detected on lymphocytes from two male pseudohermaphrodites with 46,XY karyotypes and testicular tissue.

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Fatal connective tissue disease with antinuclear antibodies following PUVA therapy. There were 96 patients aged greater than or equal to 65 years and 26 patients less than 65 years. The technique presented here allows one to study the specific involvement and contribution of pulmonary endothelium in various lung diseases.

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Here we shall review the work carried out in our lab in recent years and show that NB cells express tumor-associated antigens, such as MAGE-3, but lack constitutive expression of costimulatory molecules and surface HLA class I and II molecules. Neuropsychological deficits in adolescents with conduct disorder and comorbid bipolar disorder: a pilot study.

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A consecutive sample of 17 patients presenting with isolated tripod malar fractures over a 42-month period. Five axenic cultures and a mixed culture were examined for ability to degrade South Louisiana, Brass River Nigerian, Anaco Venezuelan, and Altamont crude oils. Fractionation of the multiple forms of bovine gastric aspartic proteases by chromatofocusing.

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Traumatic paresis of the serratus anterior muscle (diagnosis, clinical aspects, treatment) However, the distribution of the damage was different and the survival time was longer.

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Needle-less local anesthesia: clinical evaluation of the effectiveness of the jet anesthesia Injex in local anesthesia in dentistry. No difference in survival was observed in the treatment of rabbits with endocarditis due to the beta-lactamase-negative strain. The effect of some commercial dentifrices on the growth of Streptococcus mutans

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The authors also emphasise the advantages and drawbacks of each particular drug, and the potential combined use of agents with complementary mechanisms of action. The proposed method has an ability to obtain reasonable networks with a short computational time. In combination with ethanol it decreased the activity of PFK and LDG in all studied brain areas and increased glucose and lactate levels. At a concentration of 0.1 mg/ml it gives no visible effect on the water and sodium permeability, but inhibits the effects of ADH, forskolin and cAMP.

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The study purpose was to examine how parathyroidectomy for SHPT impacts KDIGO targets during immediate and long-term follow-up and to evaluate KDIGO categorization with receipt of additional surgical intervention. The stand age distribution peaked at 60-100 years across the region, with hardwoods typically younger than softwoods. These changes were fully reversed within 1 h of removing the MCCM. The procedure, which employs the gracilis muscle for the sphincteric reconstruction is described and the operative results and complications are analysed in 24 patients submitted to this type of surgery.

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For individual droplets, we show that coarsening kinetics are modified when disilane or oxygen is added: coarsening rates increase in the presence of disilane but decrease in oxygen. The effect of angiotensin converting enzyme (ACE) inhibition by captopril on these responses was also investigated. Measurement of DNA damage in urinary bladder epithelium by alkaline elution assay Immunological crossreactivity of Paramecium surface antigens: conformational differences account for cell surface specificity.

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The most recalcitrant and disturbing of all these problems is the relentless bone loss associated with negative calcium balance. Southern blot analysis showed that only the motility-negative mutant contained the transposon, whereas the HA- mutant was a spontaneous kanamycin-resistant mutant.

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Amelioration of analbuminemia by transplantation of allogeneic hepatocytes in tolerized rats. Anti-idiotypic antibodies in a patient with a functioning renal graft.

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Studies on the toxicokinetics and biochemical effects of acrylamide are reviewed in regard to their implications concerning the mechanism of acrylamide induced neuropathy. Future expectations concerned improved mobility, cosmetics, and sensory feedback. Nanotemplate-engineered nanoparticles containing gadolinium for magnetic resonance imaging of tumors.