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Medical students appeared to change their attitudes concerning the degree to which medical intervention is appropriate as a result of preclinical or general medical experience. The pathogenesis of these various aspects of reproductive failure are discussed herein. The decrease in basal PRA was much more pronounced in the unilaterally nephroadrenalectomized rats drinking saline, with or without adrenal enucleation.

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How lambda repressor and lambda Cro distinguish between OR1 and OR3. Labeled fibers could be traced from the dorsal hippocampal commissure (the dorsal psalterium) into the rostral tip of the fascia dentata (the fasciola cinerea) and from the terminal field of the crossed temporo-ammonic tract in regio superior into adjacent portions of the stratum moleculare of the fascia dentata.

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Glutamate decarboxylase distribution in discrete motor nuclei in the cat brain. We suggest that the rate-limiting step in the intracellular transport of both types of IgD is the passage from the ER to the Golgi complex.

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Clinical studies focusing primarily on blood pressure control with combinations of antihypertensive medications. The incidence of prostate cancer has recently increased in Japan. The treatment effect appeared to be fully established after 6-8 weeks and no side-effects could be ascribed to the active treatment. The results demonstrate the dynamic functional compartmentalization of respiratory chain substrates, with the existence of a substrate pool that can be recruited to maintain energy production at normal levels when respiratory chain complexes are inhibited. Here, PP4 catalytic subunit has been purified from porcine testis to near homogeneity and a specific activity of 680 mU/mg against phosphorylase alpha.

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Laser preconditioning of calvarial bone prior to an X-ray radiation injury: a preliminary in vivo study of the vascular response. Frontotemporal dementia, semantic dementia, and Alzheimer disease are associated with distinct neuropsychological profiles that classify these dementia syndromes with considerable success. Depending on the type of tissue, Ras proto-oncogenes appear to either promote or inhibit the tumor phenotype. Furthermore, sera collected 1, 2, and 3 months after graft removal from one patient and serum collected 3 months after spontaneous resolution of a perigraft seroma from another patient failed to inhibit fibroblasts. At the origins of the superior and inferior heads there are regions in which the fibres are interlaced or closely overlapped by fibres of either the temporalis muscle or the medial pterygoid muscle.

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Identification and characterization of a beta-adrenergic receptor in hamster Sertoli cells. Subpopulations of human peripheral blood suppressor cells regulating lymphocyte response to different doses of concanavalin A A dose-response effect was noted with both BCNU and adriamycin, with increased potentiation being observed with increasing doses of the anticancer agents. We compared cytokeratin 15, (CK15), T-cell death-associated gene 51 (TDAG51), cytokeratin 20 (CK20) and androgen receptor (AR) in differentiating these tumors and assessed their expression in BCC subtypes. Improved radiochemical assay for carnitine and its derivatives in plasma and tissue extracts.

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Star-shaped polycaprolactone-polyethyleneglycol copolymer micelle-like nanoparticles for picropodophyllin delivery. H-antigen staining within the entire tumor did not correlate with the stage of the tumor, i.e., spread of the tumors. Synthesis of (S)-3,4-diaminobutanenitriles as precursors for 3-amino-GABA derivatives.

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Only one patient, who initially had none of the criteria of pre-leukaemic state, responded to androgen treatment with a 4-year complete remission but died on the 5th year of acute myeloblastic leukaemia. Audiological test results of the autoimmune sensorineural hearing loss On the basis of these results, clinical investigations can be undertaken. A case of multiple retention of primary teeth and delayed eruption of the permanent dentition. Therapeutic response relationship to phenobarbital and diphenylhydantoin serum and cerebrospinal fluid levels in epileptics.

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Ion permeability induction by the SH cross-linking reagents in rat liver mitochondria is inhibited by the free radical scavenger, butylhydroxytoluene. Elevated temperature stimulates the increase of ISP1 level when applied immediately after the transfer of cells from the growth to the sporulation medium (at T0) or at T3, when sporulation becomes irreversible. Electron microscopic studies on pedicled grafts of alveolar mucosa and on newly formed periosteal epithelium

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Pericardial defects rarely cause clinical symptoms and thus are not often recognized. Unbound and non-covalently bound steroids were adsorbed by prolonged dextran-coated charcoal treatment. We contend that this argument is incompatible with the growing requirements of barley. In this study we show that a close structural derivative of CHX, acetoxycycloheximide (E-73) induced rapid processing of procaspases and subsequent apoptosis with much higher efficacy than CHX in human leukemia Jurkat T cells. The objective of this study was to analyze whether brain activation patterns of homosexual pedophiles differed from those of a nonpedophile homosexual control group during visual sexual stimulation.

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The mosquito sampling efficiency of the Mbita trap was compared to that of the CDC light trap and the human landing catch in western Kenya. Breast cancer brain metastases (BCBM) are challenging complications that respond poorly to systemic therapy. Comparative in vitro activities of enoxacin (CI-919, AT-2266) and eleven antipseudomonal agents against aminoglycoside-susceptible and -resistant Pseudomonas aeruginosa strains. DLR is a multipotent and suitable method for many aspects of imaging treatment verification.

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Assessment of phagocytic capacity and opsonic activity in blood and mammary secretions during lactation in sows. This isoenzyme was induced in rats by gavage with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) or by exposure of early RTE cell cultures to TCDD, provided RA was also added to the cultures. Lead nitrate affected the gliding velocities of microtubules starting at concentrations above 10 microM and reached half-maximal inhibition of motility at about 50 microM. Function of the repeating homologous sequences in nucleic acid binding domain of ribosomal protein S1.

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Ultrastructurally, TEDC had features most similar to epidermal indeterminate cells. Curve-shift was used to test the effect of SCH 23390, a dopamine D1 receptor antagonist, and GBR-12909, a selective dopamine uptake blocker, on self-stimulation behavior. Effect of drying Taxus needles on their taxol content: the impact of drying intact clippings. Twenty-six failed to accurately report research results, thirty-six failed to mention significant research limitations, and only five quoted a third-party expert source. Increased attention has recently been directed at the possibility that the clinical efficacy of immunotherapy might be elaborated by alteration of T-cell reactivity.

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Examination of premature infants revealed a 31 per cent incidence of chordee and serial examinations of a 27-week gestational age infant demonstrated gradual complete correction of the chordee during the ensuing 6 weeks. The following conclusions can be drawn from the whole body of data: (1) Gene patterns of Pygmies are those typical of other Africans (e.g.: lack of ADA2 and AK2 genes, low GPT2 gene frequency, polymorphism of the CA2 locus, and presence at polymorphic frequencies of PEPA2 allele. Observations of the intrasplenic position of the aggregated material within 8 hr of its injection into normal and decomplemented mice suggest that the early phase of localisation in germinal centres depends on binding to lymphocyte C3 receptors.

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Freeze-fracture electron microscopy is suitable for the study of membrane plane ultrastructures, since it reveals a wide planar view of the membrane by splitting it along the hydrophobic membrane internal plane. In contrast, the elevations in serum cortisol concentrations observed in response to these noxious stimuli were not noticeably affected.

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HL60 is a human promyeloid cell line capable of differentiating towards monocytes or granulocytes when treated with appropriate agents. Based on the WHO (1977) definitions of satisfactory reproducibility, most examiners showed satisfactory intra-examiner reproducibility of the aggregate data, but a less satisfactory performance was found for the intra-examiner reproducibility using the qualitative approach, and for inter-examiner reproducibility using both approaches. Central administration of atrial natriuretic factor inhibits saline preference in the rat.

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I have purified a high molecular weight actin filament gelation protein (GP-260) from Acanthamoeba castellanii, and found by immunological cross-reactivity that it is related to vertebrate spectrins, but not to two other high molecular weight actin-binding proteins, filamin or the microtubule-associated protein, MAP-2. Studies of some factors affecting the cell growth supporting capacity of calf serum. Other related compounds tested, including oleandomycin, clarithromycin, spiramycin, and virginiamycin M1, did not influence assembly. Clinical signs of infection, such as fever and leukocytosis, were common in patients with graft-to-enteric fistula and bowel ischemia. We report 5 cases of pneumonia caused by beta-lactamase-producing strains of Hemophilus influenzae.

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In the presence of ascorbic acid, the level of collagen I secretion was higher for each individual component and for the mixture. Skin-sparing mastectomy (SSM) is a variation of modified radical mastectomy (MRM) optimized for reconstruction. CASL perfusion MRI measurements of CBF on a 1.5-T GE Signa magnet were repeated in young healthy male and female subjects at one hour and one week. To focus the efforts of a hospital-based injury prevention outreach program, information on patient demographics, community characteristics, and catchment area must be known. By immunofluorescence, typical basement membrane structures were stained with both mAbs on frozen sections of different human organs.

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The normal ranges for ALT have been updated and validated considering the metabolic covariates in the various ethnic districts. The maximum map specific lod score obtained was 3.56 at PGK1P1 (Xq11.2-12). Polarity of structure and of ordered nerve connections in the developing amphibian brain. Dream Support is positively related both to Dream Success and to mental health factors while resistance to the Dream is not.

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Structural Equation Models demonstrated that recollections of caring, non-intrusive parenting behaviors were significantly, negatively associated with the prevalence of mood and anxiety disorders (but not substance disorders) in young adulthood. Current controversies in sentinel lymph node biopsy for breast cancer.

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Three children had obstruction of the upper moiety and eight had obstruction of the lower moiety. Surgical treatment of tibial shaft fracture: experience of 207 cases. Treatment of cultured melanoma cells with dbc-AMP resulted in a selective induction of type-A TNF-receptors, without affecting the type-B receptor level. Since the mechanism of action of vasodilators is reasonably well understood, vasodilator therapy can be administered safely in anticipation of both improvement in total cardiac performance and a decrease in severity of ischemia. This group has not been specifically studied in the DOAC randomized controlled trials and, hence, extrapolation of these data into this population should be done cautiously.

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pombe HSF was not inhibited by cycloheximide, suggesting that induction occurs posttranslationally, and the induced factor was shown to be phosphorylated. Frog skeletal muscle contains a kinase activity that phosphorylates inositol 1,4,5-trisphosphate to inositol 1,3,4,5-tetrakisphosphate. The diagnostic accuracy of thyroid dysfunctions is primarily affected by the validity of the reference interval for serum thyroid-stimulating hormone (TSH). After their disappearance, coiled bodies are not seen to re-form, although injected cells remain viable for at least 3 d.

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It gave no evidence of morphological (pre-capillary) arterio-venous shunts or of increased pulmonary arterial pressure. Autoradiographic analysis of protein synthesis and measurements of nuclear volume in WISH cell cultures irradiated with 3 GHz electromagnetic radiation. Post traumatic leptomeningeal cysts (P.T.L.C.) are capsulated liquor collections in the sub-arachnoidal space consequent to skull fractures. Peak amplitudes increased with age until after eye opening (PND 15), but were variable thereafter.

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These were followed after a delay by a number of proteins of higher molecular weight, traveling at the same fast rate. In case 2 the electrocardiogram revealed sinus bradycardia, a prolonged S-T interval and recurrent ventricular fibrillation. There were no racial differences in either patient or graft survival. Adaptation did not occur at higher intensity levels which completely eliminated cocaine-maintained responding, even when this intensity was tested prior to intermediate intensity levels. This communication describes the presence of 1-methyl-beta-carboline (harman) in the hypophysiotropic area of the hypothalamus which incorporates the arcuate nucleus.

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At pH 6.0 the reaction was slow and at pH 1.9 little or no transpeptidation was observed. Finally, we compare methods (route) of vaccine administration under farm conditions and evaluate immune response in vaccinated rabbits.

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The biological differences that distinguish these two populations might explain part of the differences observed in their mortality rate, regardless of the effect of surgery. They review existing literature on discharge planning and outline how the results and lessons of the pilot study will help develop a full audit and quality cycle in the future. Endorectal ultrasonographical imaging during ejaculation, a recently developed diagnostic procedure, may provide a new approach to ejaculation-related problems. There is a progressive reduction of testicular weight as the interval between cadmium and antagonist administration increases.

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Effects of oligomycin and acidosis on rates of ATP depletion in ischemic heart muscle. To facilitate detection of protein fatty acylation, p59fyn was overexpressed in COS cells and incubated with radioiodinated fatty acid analogs of myristate (IC13) or palmitate (IC16). Cells synchronized by this technique were challenged with DMSO and analyzed for kinetics of commitment to the differentiation program.

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Characterization of the stable L-arginine-derived relaxing factor released from cytokine-stimulated vascular smooth muscle cells as an NG-hydroxyl-L-arginine-nitric oxide adduct. HLA typing showed a specific profile A1 B8 DR3 (risk factor of auto-immunization during interferon alpha therapy) with antinuclear antibodies and anti smooth muscle antibodies.

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201T1 study of regional myocardial perfusion using a gamma counter and the EC1020 computer Treatment hypercalcemia crisis consisted of rapidly lowering the serum calcium level by various measures while actively treating the primary diseases.

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Allogeneic stem-cell transplantation with reduced conditioning intensity as a novel immunotherapy and antiviral therapy for adult T-cell leukemia/lymphoma. Both nylon wool-adherent and -nonadherent peripheral blood leukocyte populations contained suppressor activity. (2) Alveolar pressure is computed from the box pressure signal, using instantaneous values of the intrathoracic gas volume. An analysis of sagittal T1-weighted MR studies was performed in 23 patients with hydrocephalus, 58 patients with atrophy, and 100 normal patients.

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A possible role for PPD-reactive T lymphocytes in cell-mediated protective immunity in newborns is discussed. The tumor had a low 5-bromodeoxyuridine (BrdU)-labeling index and low AgNOR count. The spectrum of antibacterial activity of these agents is discussed in relation to the common organisms encountered in general practice. Our calculations are carried out using empirical force constants that are not further refined to low-frequency spectra. The aperture weighting function can be used to match the spectral shape to the photodetector size, which then optimizes the dynamic range.

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Humoral immune response as predictor of recurrence in Clostridium difficile infection. Furthermore, when performed in this way, the time course of tracer equilibration occurs over several minutes, rather than the sub-second range expected for tracer equilibration into channel-containing vesicles in the absence of an opposing chemical gradient of the permeant ion.

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In experiment 1, the younger MA children were more likely than the older MA children to learn the discrimination on a configurational basis. Quantitative and qualitative data on the course of delirium was gathered, as well as important demographic and medical variables.

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Attenuation of gamma interferon-induced tyrosine phosphorylation in mononuclear phagocytes infected with Leishmania donovani: selective inhibition of signaling through Janus kinases and Stat1. Expression of sterol regulatory element-binding protein-1c mRNA was significantly lower 12 h after alcohol or beer exposure, while fatty acid synthase mRNA expression was induced in livers of ethanol-fed mice and to a lesser extent in mice fed beer 6 h after acute alcohol ingestion. Laparoscopic diagnosis and pseudomenopause treatment of endometriosis with danazol.

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The corresponding values for inter-alpha-inhibitor, 0.16 and 0.001, respectively, indicate that its capacity to pass through the vascular endothelium is relatively high whereas transfer to bile is restricted. Characterization of genomic imbalances in diffuse large B-cell lymphoma by detailed SNP-chip analysis. Beginning on that date, hospitals will have to ask whether every patient they admit has an advance directive--a living will or a durable power of attorney for health care. The discrete reaction products are localized preferentially in the apical part of the visceral yolk-sac epithelium.

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The theoretical method employed here has a general application for the calculation of small conformational changes of globular proteins upon their chemical modification or an amino acid substitution. We show here that evolution itself can be used to filter sequence and structure data in order to identify evolutionarily important amino acids.

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None of the other 14 girls had disease restricted to the pelvis. This probe detects RFLPs at the S mu and S alpha 1 loci by enhanced chemiluminescence. In addition, an increased evocability of a positive feedback effect of oestrogen was observed in such genetic males. UV-A induced oxidative stress is more prominent in naturally pigmented aged human RPE cells compared to non-pigmented human RPE cells independent of zinc treatment.

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Finally, after complete surgical resection and histopathologic examination, one case was diagnosed as cystic change of metastatic lymph node from thyroid papillary carcinoma, and the other was determined to be a branchial cleft cyst with concurrent lymph node metastasis from thyroid papillary carcinoma. Pathological studies showed that cyanide treatment had no marked effect on the microanatomy of the tissues examined. immunoglobulin because of persistence of anemia requiring blood transfusions. However, since 2010 the anti-CTLA-4 antibody ipilimumab and the BRAF inhibitors, dabrafenib and vemurafenib, have demonstrated initial signs of efficacy in active brain metastases.

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Of the ones diagnosed by this method, is the first case published in our country and the eight of all that have been reported until this moment. In particular, the formation of pollutants is a complex, nonlinear and multi-scale process characterized by the interaction of molecular and turbulent mixing with a multitude of chemical reactions with disparate time scales. subalatus Champion, is placed in synonymy with the genus Charisius. Acrylamide given to rats after damage to the posterior tibial nerve by a tight ligature causes retrograde degeneration of axons.