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A case of skull base malignancy following long-term sinus mucocele is presented. This review discusses some of the reasons why pulmonary drug delivery is becoming an increasingly popular route of administration and describes the various investigations that have been undertaken in the preparation of spray-dried powders for pulmonary drug delivery. Proceedings: A radiological study of morphology and growth in the human fetal colon. The primary outcome measure was the proportion of subjects with intraoperative hemostasis at 4 min after start of randomized treatment application.

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To evaluate the effect of insulin on a receptor-positive tumor, we examined the direct effect of insulin on an estrogen receptor and its subsequent biologic effect on a receptor-positive endometrial carcinoma model in vitro and in vivo. Distribution of 2 polymorphisms of the chemokine receptor CX3CR1 (V249I and T280M) was determined in a population-based sample of 1179 elderly individuals. Selective serotonin reuptake inhibitors are better tolerated than tricyclic antidepressants as measured by total numbers of drop outs.

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As IL-2 is needed to initiate and sustain immune responses and IL-12 promotes Th1 responses, this may contribute to the Th2-skewed pattern in atopic children. Positive staining for MMP-3 was seen in the osteoblasts and osteocytes, and TIMP-1 was mainly localized in osteoblasts. Fifty-five female osteoarthritic patients with 85 osteoarthritic knees were studied.

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Resuscitation of patients with ischaemic heart disease before admission to hospital. This study reports the first Asian family that has been demonstrated to carry a BHD mutation. Molecular gene cloning, expression, and characterization of bovine brain glutamate dehydrogenase. Drug interactions in dental practice: a summary of facts and controversies.

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We describe an infant with hypoplasia of the left heart diagnosed prenatally who, at birth, had signs of severe pulmonary venous obstruction. These results suggest that, although the quintet members other than APRR1/TOC1 may not be directly integrated into the framework of the central oscillator, they are crucial for a better understanding of the molecular mechanisms underlying the Arabidopsis circadian clock. The MR appearance of the two cases with partial tears was similar to that of full-thickness tears. The socket preservation technique has demonstrated to be effective in maintaining volume before implant placement. Smoking and changes in body weight: can physiopathology and genetics explain this association?

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These deposits, acting as a foreign body, further intensified the inflammatory response, resulting in extensive alveolar bone loss and external tooth resorption. The indications for coronary angiography have been changing in recent years. Efficacy in the rat, associated with hepatic weight reduction and cardiac and renal hypertrophy. The binding constants of these substances on wool protein are shown. Stimulation of monocytes/macrophages with activated nonadherent cells allows productive nonlytic growth of human cytomegalovirus (HCMV), but the viral replication cycle is delayed relative to replication of HCMV in human fibroblasts.

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Zofran (8 mg in 500 ml Ringer solution) was injected intravenously one hour before intubation at a flow rate of 8 ml. Considering the rare occurrence of leiomyosarcoma of the breast, in radical surgery we used attitudes like in other breast tumors and leiomyosarcoma of other localizations. Due to the high prevalence of pre-diabetes, lack of awareness of diabetes and less likelihood of receiving adequate treatment in lower SES group, there is potential for the rapid increase of diabetes. Bezafibrate is a latest generation fibrate derivative that substantially reduces total plasma cholesterol and triglyceride concentrations and increases high density lipoprotein (HDL) cholesterol. The endonuclease P2A initiates the DNA replication of the bacteriophage P2 by making a covalent bond with its own phosphate backbone.

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MRL/1 and BXSB mice were treated daily with cyclosporin A (CyA) in an oral dose of 25 mg/kg body weight. Urinary beta 2-microglobulin and renal functions in elderly people in an area with no known cadmium pollution (Japan). Cytotoxic effect of glutamate and its agonists on mouse hippocampal neurons. Influence of vitamin C on the metabolism of arachidonic acid and the development of aortic lesions during experimental atherosclerosis in rabbits.

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These techniques allow for a wide range of applications, like warfare agent detection, chemical reaction control, mass spectrometry imaging, polymer identification, and food safety monitoring, as well as applications in biomedical science, e.g., drug and pharmaceutical analysis, medical diagnostics, biochemical analysis, etc. Whereas stimulation of ETAR on nociceptors always elicits a pain response, stimulation of ETBR may cause analgesia or elicit a pain response, depending on the conditions. Specifically, the exchange of solvent molecules bound to unsaturated Cr(CO)5 in methanol solution has been investigated. Species exist within communities of other interacting species, so an exogenous force that directly affects one species can indirectly affect all other members of the community.

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Our findings support universal chlamydia testing of young women detainees. The effect was studied of various concentrations of ammonia (5, 20, 50 and 100 ppm) on 20-day old chicken broilers for 120 min. A new method of percutaneous endoscopic gastrostomy (PEG) using V-shaped transmural suture fixation was performed on 2 patients with advanced carcinoma. Development of a practical electrical stimulation system for restoring gait in the paralyzed patient.

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Furthermore, inhibition of the EGFR also attenuated focus formation in NIH 3T3 expressing the CXCR2. One molecule of each of these subunits is present in the assembled complex, as there is also in each native F1F0-ATPase assembly. Due to the large variation in ASR composition, the model predicts that ASR gasification is industrially feasible only if a blend of ASR and RDF is used as a reactor feed. We conclude that the elimination of N-linked oligosaccharide chains in the envelope N-terminal domain do not prevent receptor interaction but results in subtle conformational changes that may alter recognition and binding. H-7, a potent and specific PKC inhibitor, however, inhibited the proliferation of both cell lines induced by IL 2.

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Autoradiograms of the slab gels indicated that two surface components of approximately 80,000 and 35,000 mol wt were much less exposed or were missing on the resistant line. When developed cells were stimulated with cAMP, fluorescence due to ABP-30a and ABP-50 increased in the cortical region 5 to 10 sec after stimulation.

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Role of a cefoxitin-inducible beta-lactamase in a case of breakthrough bacteremia. Development of a PCR for specific detection of Mycoplasma bovis from bovine milk and mucosal samples: a critique. From these results, it was suggested that prodrug 1 was slowly absorbed primarily from the lower small intestine.

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It was readily maintained in tissue culture and was transplantable to adult rats. coli-Induced Pathogenicities through Disease-Associated Alpha7 Cholinergic Pathway and RNA Sequencing-Based Transcriptome Analysis of Host Inflammatory Responses. Prospective diet surveys in patients indicated a mean oral caloric intake of 902 kcal/day.

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Blood pressure percentiles by age and height for children and adolescents in Tehran, Iran. Cyclosporin-A in vitro decreases bone resorption, osteoclast formation, and the fusion of cells of the monocyte-macrophage lineage. This pilot trial demonstrated the acceptability and preliminary efficacy of e-SBI plus tailored mailings for alcohol use in pregnancy.

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During the last fifteen years, endoscopic sclerotherapy has been established for the treatment of bleeding esophageal varices. pallidus was higher in plain villages while the percentage of An. Stimuli applied 90 ms after the R-wave provoke maximal lowering of mean arterial pressure. To study the prevalence and predictive factors of suicide attempts among Chilean adolescents. These poor results led to the investigation of systemic chemotherapy as part of the combined modality treatment for patients with locally advanced head and neck cancers.

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3) Gastric metaplasia in the duodenal mucosa can be colonized by H pylori resulting in chronic duodenitis. Effects of mannitol on brain blood flow and metabolism during resuscitation Recent evidence suggests that theophylline, apart from bronchodilatation, derives its therapeutic activity in asthma from anti-inflammatory effects. The alpha subunit of tubulin from mitotic apparatus and from A microtubules of ciliary doublets is resolved into two bands, while the alpha subunit of flagellar doublet tubulin gives a single band. Enoxaparin, a low-molecular weight heparin, is effective in prevention and treatment of VTEs.

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Therefore, it can be concluded that the changes of chondrocytes to fibroblast-like cells in monolayer culture are accompanied by changes of integrin genes. PVP-citric acid and PVP-indomethacin form non-ideal miscible systems at all compositions. Eight weeks after experimental coronary artery ligation or sham operation, ejection fractions were assessed by echocardiography. A relatively stable enzyme system that converts versiconal hemiacetal acetate to versicolorin A was isolated from the soluble fraction of the homogenized cells of Aspergillus parasiticus ATCC 15517.

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Nuclear DNA ploidy pattern and tissue levels of dihydroxyphenylalanine and catecholamines in pheochromocytoma. Association of Epstein-Barr virus with leiomyosarcomas in young people with AIDS.

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Seven RPM specimens from 7 eyes were stained with hematoxylin-eosin, cytokeratin 7, cytokeratin AE1/3, smooth muscle actin, vimentin, and CD34. Maturing erythroblasts and erythrocytes were studied in chickens and adult hens to provide more information on the presence and frequency of various nucleolar types in these cells.

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The identification of the interaction sites in dystrophin and beta-dystroglycan provides further insight into the structure and the molecular organization of the dystrophin-glycoprotein complex at the sarcolemma membrane and will be helpful for studying the pathogenesis of Duchenne muscular dystrophy. The cementum surface of permanent teeth without pathology, presented frequently such resorption aspects around their apical regions as well as on other regions, the resorbed areas being more often not widespread. Sampling and recruitment in multilevel studies among marginalized urban populations: the IMPACT studies. Clinical experience with apomorphine hydrochloride: the first 107 patients. Both the patient and his father were later discovered to have an underlying metabolic susceptibility to malignant hyperpyrexia.

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The way in which uAPTTs are evaluated in laboratories was assessed in this international study with the aim of determining whether laboratory professionals are able to fulfill this need. Bioassays of pituitary PRL extracted with Lubrol and alkaline medium, were less effective in quantifying PRL than RIA. Left ventricular diastolic function in children measured by Doppler echocardiography: normal values and relation with growth.

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Cervical spine injury, with an incidence of 15 cases per year, began to be reported in the 1980s. These two cross-sectional surveys conducted five years apart collected detailed activity limitation information about persons over 15 years of age.

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Prospective injury data were obtained by examination of athletes injured from 1975 through 1977. Chloride transport inhibition by piretanide and MK-196 in bullfrog corneal epithelium.

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LEW recipients of ACI vascularized hind limb allografts were analyzed for lymphoid chimerism by a complement-dependent cytotoxicity assay using antisera produced across this strain combination. Cancer cell surface induced peptide folding allows intracellular translocation of drug. ANG II caused no detectable increase in ERK activity or in c-fos mRNA abundance in ARVM but increased ERK activity within 5 min in CMEC and increased c-fos mRNA levels.

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Hyperuricemia can lead to gout, and may be a risk factor for cardiovascular events, hypertension, diabetes and renal disease. Combination therapy in hypertension is often required because many patients cannot be controlled on one drug alone.

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Analysis of operative mortality after portal decompressive procedures in cirrhotic patients. The efficacy of a single dose of prostaglandin F2 alpha gel instilled into the extra-amniotic space to induce termination of pregnancy in the second trimester has been assessed and compared with intra-amniotic prostaglandin F2 alpha and with an extra-amniotic infusion of prostaglandin F2 alpha combined with intravenous oxytocin.

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gracilis D-amino acid oxidase (DAAO) gene labeled by EGFP in HeLa cells and how it mediates cytotoxicity, DAAO cDNA and EGFP gene were cloned into Eukaryotic expression vector pIRES to construct DAAO gene expression vector pIRES-DAAO. The purpose of this study was to identify strengths and needs of Japanese grandparents as perceived by three generations. The cell lines maintain a high degree of resistance to ricin after growth in lectin-free medium for prolonged periods and therefore exhibit stable phenotypes that are different from normal BHK cells.

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Prolongation of gastric bleeding time has been postulated as a mechanism for gastric hemorrhage after aspirin in man. This effect was no longer detectable after either addition of LC-GP or papain treatment of HC-GP. DNA synthesis was assessed by measuring the fluorescence intensity of FITC-conjugated antibody to bromodeoxyuridine (BrdUrd). Another mycotoxin in ryegrass is sporidesmin, which causes liver damage and secondary photosensitization (facial eczema). Mediastinal masses of various origins can be encountered on imaging in symptomatic or asymptomatic patients.

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Comparisons are performed at the national level and within the Dartmouth Hospital Referral Regions (HRRs). Deletion of the 136 bp SalI-NheI fragment just downstream of the transcription initiation site caused the constitutive expression of the faoA-lacZ fusion protein in P.

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MMC-CH yielded high drug concentrations in intraabdominal tissues and exhibited remarkably low levels in extra-abdominal tissues and peripheral blood. Extracellular carbohydrate-signal triggering cAMP-dependent protein kinase-dependent neuronal actin-reorganization. Hemodynamic changes during laparoscopic cholecystectomy monitored with transesophageal echocardiography. Ultrastructural and functional characteristics of the cell populations composing the cultures derived from mouse thymic explants.

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To document orofacial rehabilitation and outcomes after full thickness orofacial burn. Both incidence and cure rate of anastomotic leakage after total gastrectomy had markedly improved, in spite of increased resection rate and curative operation for the patients with advanced gastric cancer by introducing TPN routinely to the nutritional management.

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Meconium-instilled rabbits intravenously received dexamethasone (0.5 mg/kg) at one dose 0.5 hours after meconium instillation or at two doses 0.5 hours and 2.5 hours after meconium instillation or were left without treatment, and were oxygen-ventilated for additional 5 hours. An investigation of the disintegration of tablets in biorelevant media. Percentage alterations in the lenticular metabolite concentrations from UVR-B exposed rabbits were calculated relative to the levels in the control group. Distinguishing thest tumors from carcinomas or sarcomas may be difficult, and patients are generally in the same age range as those with cancer. S antigen reaction was stronger in secondary infections in tests with various subunit antigens.