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The sugar components present in all LPS were glucose, galactose, L-glycero-D-manno-heptose, 2-keto-3-deoxy-octulosonic acid and glucosamine. State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology. Basic fibroblast growth factor in retinal development: differential levels of bFGF expression and content in normal and retinal degeneration (rd) mutant mice. Thromboxane, prostacyclin, beta-thromboglobin, and diabetes mellitus.

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ITM may be a useful adjunct to PCA, but did not decrease time to ambulation or length of stay. This suggests that patients with acute leukaemia had not been constitutionally deficient in NK cell activity.

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Renal tissue metabolism in the rat during chronic metabolic alkalosis: importance of glycolysis. Recent improvements in detecting these changes and more importantly showing reversal or improvement by neomycin or a low protein diet are a major advance.

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The dynamics of the spontaneous electrical activity of the rostral, dorsal, ventral and caudal claustrum was studied chronically in 12 dogs with biologically significant distinctions in the physiological state of the animals: extinction of orientative reflexes, replacement of the feeding conditions for the acid and defensive situation and elaboration of internal inhibition. A computational study of the open and closed forms of the N-lobe human serum transferrin apoprotein.

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Extremely small amounts of IL-7 are made by stromal cells, which are themselves being thoroughly studied as cloned cell lines. Combination therapy of leupeptin with Trasylol conferred no additional benefit over animals treated with leupeptin alone. Cord blood IgA and IgM levels were measured in newborns of mothers with prematurely ruptured membranes (PRM) who had also received prenatal glucocorticoid treatment to accelerate fetal lung maturity.

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The results show that the flame topography obtained from tomographic chemiluminescence and the Mie measurement agreed qualitatively (i.e., both methods yielded the same profile of the flame fronts), but a quantitative difference on the order of millimeters was observed between these two methods. The persistence of high gradients may hinder or delay the regression of left ventricular hypertrophy after aortic valve replacement. Transcutaneous H2 clearance--a new least-invasive method for assessing skin blood flow. In this study the lymphocyte function of therapy matched rheumatoid and non-rheumatoid patients in the mitogen mediated in vitro whole blood microculture system has been analyzed. We have detected xanthine oxidoreductase activity in unfixed cryostat sections of rat and chicken liver, rat duodenum, and bovine mammary gland using the tissue protectant polyvinyl alcohol, the electron carrier 1-methoxyphenazine methosulfate, the final electron acceptor Tetranitro BT, and hypoxanthine as a substrate.

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Although corticosteroids are often used to lower intracranial pressure acutely, corticosteroid withdrawal after long-term administration may induce increased intracranial pressure. The artifact can usually be eliminated by taping the auricle down. Calves became infected with BCV following inoculation with either ELISA-positive or ELISA-negative but IEM-positive feces. The Sip-imposed restriction on the growth of lambda immP22 phages is not observed if the phage carries a mutation in the c1 gene.

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The study was divided into Baseline, EMG Feedback Training, Feedback Training Plus Incentives, and Follow-up treatment conditions. It could be shown that the use of a long capillary column is an easy and effective approach to reduce ionization suppression by enhanced chromatographic resolution. A positive correlation was observed between urinary oestrogen excretion and plasma HPL concentration.

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In NYHA class IV, isoprenaline stimulated adenylate cyclase about twofold but xamoterol, like pindolol or propranolol, had no effect. No beneficial role for glucagon in routine excretory urography was demonstrated. However, the kinetics of the C-peptide responses to intravenous glucose in all eight patients tested revealed an absent first-phase release and a delayed peak response consistent with transplantation and/or engraftment of a suboptimal islet cell mass. The modified EHDV-2 with a duplex Seg9 gene was genetically stable during serial passage in BHK-21 cells. Using antibiotic therapy, immune substitution and surgery in combination, the boy was cured.

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The effect of dietary protein levels on the rate of lipid synthesis from glycerol-3-phosphate was studied in the rat. Alternative designs that can appreciably increase these rates would greatly enhance their ability to communicate. Prenatal supernumerary r(16) chromosome characterized by multiprobe FISH with normal pregnancy outcome. To create a systems-oriented theory/model to explain the historical behaviors of interest, including the various populations of nonmedical opioid users and accidental overdose mortality within those populations. Luteinizing granulosa cells (GCs), obtained from follicular fluid of 30 women undergoing in vitro fertilization, were cultured, after a short 24-h preincubation period, in serum-free medium for 24 or/and 48 h in the presence/absence of various concentrations of AMH, BMP-15 and FSH alone or in combinations.

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Iatrogenic hypercalcemia in patients with chronic renal insufficiency Pancreatic beta-cell and gut regulatory peptide responses were investigated in 13 healthy elderly and 12 young subjects (control group) after a standard meal test. The binding of cupric ions to bovine serum albumin was investigated by using a cupric-ion-specific electrode. The effects of detection probabilities, symptomatic presentation of tumors, tumor volume doubling time, and time between screenings were examined.

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LCC15-MB cells are MDA-MB-435: a review of misidentified breast and prostate cell lines. If one accept that the induction of enzyme transforming galactose to glucose is an adaptive response of cells (organism) to galactose in the diet, then the subsequent stage of adaptation would be hepatocyte proliferation. Porcine atrophic rhinitis: a model for studying nasal physiology and pathophysiology. In the past few years, it has been disclosed that identified epigenetic alterations give rise to several typical human autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and multiple sclerosis (MS). This report summarizes the investigation conducted jointly by MDH, ISDH, and CDC, provides guidance on safe laboratory handling of Brucella spp., and makes recommendations for responding to Brucella laboratory exposures.

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Learning problems, motor control problems, abnormal responses to sensory stimuli and anxiety disorder frequently coexisted in the children. Hepatoid carcinoma of the pancreas with lymphoid stroma: first description of the clinical, morphological, immunohistochemical, and molecular characteristics of an unusual pancreatic carcinoma.

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The apparent free cortisol concentration and the free cortisol index: a comparative study. Comparative studies of the effects of the diuretics, fenquizone and chlorthalidone, in arterial hypertension We have demonstrated that CA reacted positively toward a monoclonal antibody that specifically recognized the polysaccharide determinant on cartilage proteoglycans.

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The RAS has additionally been implicated in other brain-specific functions, such as memory, cognition and stress. The diastereomeric components of the calcium channel antagonist RS-93522-004 are separated as the bis-3,5-dinitrobenzoate ester by reversed-phase high-performance liquid chromatography. Moreover recent data analyzing ERR expression in human breast tumors have proposed ERRalpha and ERRgamma as prognostic markers of these cancers. Intrauterine monoclonal origin of neonatal concordant acute lymphoblastic leukemia in monozygotic twins. These findings add to increasing anecdotal reports of psoriasis improving with dialysis and extend the observations to patients without renal disease.

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Semen alloantigens and lymphocytotoxic antibodies in AIDS and ICL. The Caenorhabditis elegans protein SAS-5 forms large oligomeric assemblies critical for centriole formation. Progression-free survival (PFS), overall survival (OS), and adverse effects were investigated. coli, of the full length p59-HBI and a series of p59-HBI mutants delimiting these domains and their respective peptidyl prolyl cis trans isomerase (PPlase) activity. The severe clinical course of this disease and the gravity of constantly fatal relapse requires highly adapted treatment and overall health care.

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This study was a cross-sectional analysis of health care staff in Khomeinishahr (centers, buildings, and networks) If they had at least 6 months work experience, they could enter the study. This review will describe the known biological effects of TRAIL, as well as the structure and possible functions of its recently identified receptors. This computerized search was supplemented by a manual search of the bibliographies of original research articles and textbooks. Anterior corneal dystrophy of American Dutch belted rabbits: biomicroscopic and histopathologic findings.

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In spite of the fact that both patients had clinical abnormalities, the more severe phenotype present in the child was probably due to the higher percentage of abnormal cells. In this review we describe surgical methods for open muscle biopsy. Both the behavioral and neurochemical dose-response curves were biphasic, with 3.0 micrograms of substance P producing a maximal response. Collection, preparation and storage of human plasma for radioimmunologic determination of thromboxane B2

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Only a small part of the hospital variation in patient outcome is related to differences in quality of care. Anion exchange mechanism for transport of methotrexate in L1210 cells.

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Local anesthetics inhibit induction of ornithine decarboxylase by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate. In contrast, complete fluorination of phosphorene gives rise to a stable structure, which is an indirect gap semiconductor with a band gap of 2.27 eV. In particular, HSP90 is crucial for R-protein-mediated defense against pathogens.

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Ionic selectivity of the sodium channel of frog skeletal muscle. The rate proportional to the association rate constant for the receptor, kon and number of receptors, Bmax, varied from 0.02-0.07 min-1 between the studied radiolabelled drugs, whereas the apparent dissociation rate was highest for clozapine. Effect of dimethylsulfoxide on the proliferation and glycosaminoglycan synthesis of rat prostate adenocarcinoma cells (PAIII) in vitro: isolation and characterization of DMSO-resistant cells.

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Results are discussed relative to research on reasoning about covariation and belief perseveration as well as perceived covariations between height, weight, and body fat. Effects of cocaine on sensory inhibition in rats: preliminary data. The results are consistent with the electromechanical model suggested for the dielectric breakdwon mechanism and with the assumption of Metcalfe, using NMR and ESR techniques, that the fluidity of the membrane increases with increasing benzyl alcohol concentration.

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Congestive heart failure is a growing problem in the Western world, which modern therapeutic options are doing little to ameliorate. Small sample size and retrospective study design are limitations. In addition, there was a good correlation between the ELISA antibody titer and the hemagglutination-inhibition or neutralizing antibody titer. The addition of penicillin G potassium (PCGk), which is contained in OK-432 at a concentration of 134,700 units/mg of dried cocci, to the LAK culture system also inhibited LAK generation at equivalent concentrations as contained in the OK-432 preparation.

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A histochemical study of the effects of 19-nortestosterone on the RNA in the secretory tubules of the submandibular glands of castrated--adrenalectomized mice. Patients fulfilling the International Classification of Sleep Disorders (ICSD) criteria for RBD were compared with non-RBD patients. Its nucleocapsid (N) protein is an ideal target antigen for SBV diagnosis. The development of sensitization to the psychomotor stimulant effects of amphetamine is enhanced in a novel environment.

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Blood supply and position of the vermiform appendix in Zambians. In the avian model, total immunoglobulin production was eliminated by bursectomy. Effect of 6-methyluracil on regulatory parameters of lipid peroxidation in thermal burn Novel chemotherapeutic and targeted agents in metastatic colorectal cancer: the time has arrived. For Chicano contraceptors, the success rate ranged from 65 per cent before the first pregnancy to 42 per cent before the fourth, a little high than for all women in the United States.

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The ventrobasal cells that responded to duodenal distension were tested further with this visceral stimulus before and after a lesion of the DC. The spike-and-wave pattern in the electroencephalogram remained a prominent feature in both groups.

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Critical Illness in Pregnancy: Part II: Common Medical Conditions Complicating Pregnancy and Puerperium. Trajectories of Alzheimer disease-related cognitive measures in a longitudinal sample. These data suggest a mechanism by which the oxidation state of conserved cysteine residues in the AP-2 DNA binding domain may contribute to its DNA binding activity. Using immunocytochemical methods, we analyzed the localization of the HSP70 protein constitutively expressed during embryogenesis in the amphibian Pleurodeles waltl. Research workers studying the relationship between stride length (L) and speed (u) in human walking have often expressed their results as multiples of stature (h): they have given values of L/h and u/h.

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Audiotaped interviews were transcribed, and thematic analysis strategies were used to identify core concepts and categories for coding interview data. Enhanced efflux of cholesterol from ABCA1-expressing macrophages to serum from type IV hypertriglyceridemic subjects. This is more marked in Australia than in New Zealand, but in both countries the relative rate (in comparison to non-indigenous rates) as well as absolute rate have nearly stabilized in recent years. Five of the 22 dogs survived with good function of the autograft as determined by glucose homeostasis and a slow return to normal of serum amylase levels.

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Outcomes of stent retriever thrombectomy in basilar artery occlusion: an observational study and systematic review. The incidence and severity of allergic asthma is rising, and novel strategies to prevent or treat this disease are needed. Freeze fracture of the gill epithelium of euryhaline teleost fish. The main presenting symptoms were mild to moderate vaginal bleeding and lower abdominal cramp-like pain, resembling the clinical presentation of a threatened abortion. This system is designed for future application in bioprocess monitoring.

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Size difference between the two allelic SCAR fragments is 42 bp and might be due to a deletion/insertion. Human urinary excretion of doxifluridine and metabolites during a 5-day chemotherapeutic schedule using fluorine-19 nuclear magnetic resonance spectrometry. Deletion or inactivation of both RB alleles is an essential, rate-limiting step in the formation of retinoblastoma and osteosarcoma that arise in families that carry mutant RB (ref. The data show that activated PMN are capable of impairing surfactant function in vitro and of degrading the major apoprotein. Serum concentrations of fasting blood glucose, total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL-C) and high-density lipoprotein (HDL-C) were analyzed.

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A significant receptor down-regulation was observed when monocytes were incubated with an excess of 125I-IFN-gamma, whereas no such down-regulation was observed in HeLa cells or in normal fibroblasts. Reoperations for hyperparathyroidism are associated with increased morbidity and decreased success. In all cases an immediate swelling is observed, specifically affecting the radial afferents below the IHCs. The degree of deviation of the AFP molecular variant pattern from the molecular pattern of AFP secreted by neonatal liver cells is independent of the total serum AFP concentration.

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The post-angiocardiography urogram in children: should it be abandoned? Subpopulations of tufted cells contain different neuropeptides and transmitters but it is not known if tufted cells forming the IAS are homogeneous with respect to neurotransmitters. Cytotoxic ability of LUV-TRAIL was assessed on Jurkat cells either over-expressing the anti-apoptotic protein Mcl1 or down-regulating the pro-apoptotic protein Bim previously generated in our laboratory.

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Pseudo-eccyesis: hemoperitoneum associated with corpus luteum hemorrhage and anticoagulant therapy. Antigenic variation by positional control of major surface glycoprotein gene expression in Pneumocystis carinii. Inhibiting caspase-8 after injury reduces hypoxic-ischemic brain injury in the newborn rat. Forty-five of them were found to have an abnormal lactose breath hydrogen test (LBHT). Colonic glycoproteins in monozygotic twins with inflammatory bowel disease.

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Thus GOLPH2-regulated GD55 may be a promising oncolytic virus agent for future liver cancer treatment. In contrast, a considerably higher yield, approximating five times that of the first week of life, was obtained in patients undergoing a lumbar puncture after the first week of life. The usefulness of flow cytofluorometry for rapidly detecting the cytokinetic changes induced in acute leukemia blasts by cytostatic drugs is affirmed.

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For optimal management of the state of HBV replication in chronic viral infection, the detection of HBV-DNA in serum was monitored by the Polymerase Chain Reaction (PCR) assay. However, the mechanisms of action of UDCA at the hepatocyte and cholangiolyte levels are still not completely understood.

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The methiothepin and cinanserin data neither confirm nor dispute the hypothesis, as their effects may have been either nonserotonergic or on serotonin receptors that were different than those acted on by the agonists. Lectin-dependent T-cell-mediated cytotoxicity is supported by con A-coupled sepharose beads.

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Enoxacin and ciprofloxacin: in vitro effect on Enterobacteriaceae, Pseudomonas aeruginosa and Staphylococcus aureus Nonhistone proteins HMG1 and HMG2 change the DNA helical structure. Primary trigeminal projection to the brain stem-reticular formation. Regulation of hCtr1 expression by cellular copper homeostasis is discussed.