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The mouse gonadotropin-releasing hormone receptor GnRH-R was used to evaluate the efficiency and potential applications of this assay. Remyelination is a critical repair process that is initiated after a demyelinating insult.

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The advantage of the USIT-tool is that is results in insight in the relevant problems, solutions and constraints of the caregivers both in the organisational and the information technological area. Transrectal Doppler sonography of uterine and umbilical blood flow during pregnancy in mares. In addition to coding regions, we also investigated correlations for complete genes and introns. Editorial: Observations on the diagnosis of isolated rheumatic carditis. We have used RT PCR and quantitative real-time PCR (qRT PCR) to investigate sex-biased expression levels of 80 A.

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Virtual screening and its integration with modern drug design technologies. Dysfunctional attitudes, negative life events, or sleep electroencephalogram were assessed in 53 outpatients before treatment with cognitive therapy. A total of 41 patients diagnosed with Williams-Beuren syndrome, who were followed up at the genetics ambulatory center of a large referral hospital, were included in the study. Water concentration in BLM was evaluated by three methods: according to the membrane permeability to water, according to the data on interface equilibrium, and directly according to the value of calculated free energy.

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It has been suggested that quantitative analysis of urinary bile acids may help to distinguish primary 3-oxo-delta 4-steroid 5 beta-reductase deficiency from the excretion of 3-oxo-delta 4 bile acids that occurs as a result of liver damage. An enzyme found previously in extracts of adult Schistosoma mansoni worms, that hydrolysed the chromogenic substrate N-acetyl-DL-phenylalanine beta-naphthyl-ester, has here been further investigated and characterized. The previously described sciatic functional index for mice is an accurate indicator of the level of sciatic neuronal function during recovery. To delineate the mechanism of action, specifically the role of exogenous myelination, NSCs derived from wildtype (wt) and nonmyelinating Shiverer (shi) iPS cell lines were used following thoracic SCI with subacute intraspinal transplantation.

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There are nine newly induced polypeptides in tolerant cultures (absent in control conditions). Unexpectedly, a decline from old age to youth in the influence of latitude was found for both incidence and mortality from melanoma of the skin in males, and for mortality in females. We attempted to determine the prevalence of strands on native and prosthetic valves, as detected by transesophageal echocardiography, and to assess the relative risk for systemic emboli associated with these strands. In addition to specified phenotypic characteristics, molecular data are required. Cooperative binding mechanisms are a common feature in biology, enabling a diverse range of protein-based molecular machines to regulate activities ranging from oxygen uptake to cellular membrane transport.

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The granules were seen in two different cell types, which differed in the electron density of their cytoplasm. The NASPE Mode Code Committee was formed in response to the growing need for efficient means of describing the function of increasingly complex single- and dual-chamber cardiac pacemakers. We used color Doppler scanning in 21 patients to determine whether there were aberrant vessels. The reaginic sensitivity to moth and butterfly in patients with bronchial asthma.

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Recent detailed information on the structure and transcription of the unusual IgD heavy chain (delta) gene in mouse suggests a complex genetic control. Expression and function of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit.

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Interaction of dexamethasone and Salmonella enteritidis immune lymphokines on Salmonella enteritidis organ invasion and in vitro polymorphonuclear leukocyte function. Quinolinate in brain and cerebrospinal fluid in rat models of congenital hyperammonemia. Cadmium Induced Apoptosis in MG63 Cells by Increasing ROS, Activation of p38 MAPK and Inhibition of ERK 1/2 Pathways.

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In contrast, IFN antagonized the VSV-associated decrease in CAMP levels. Functional brain imaging in the evaluation of psychiatric illness. Knorr-Rabe partial reduction of pyrroles: application to the synthesis of indolizidine alkaloids. The Mc1r target genes we present may be particularly relevant for understanding the ligand-independent activity of Mc1r.

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This simple topological index has proven powerful and robust for the characterization of a wide variety of electrocyclic and pseudoelectrocyclic processes. The possibility that effects the parasympathetic stimulation on the flow of juice were secondary to vasodilatation, was discussed. A high incidence of extra-articular features of RA was observed, with DR4 occurring in all cases of vasculitis (75 per cent of whom were DR4 homozygous). These results suggest a possibility that the elevation of free E2 in the serum may be one of the potential risk factors for genesis of breast cancer in Japanese women. To our knowledge, this is the first report on the treatment of an osteonecrosis in this location with a BMP, and this strategy could potentially be applied in other locations with juxta-articular osteonecrosis.

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Whole body irradiation of 800 and 1000 rad was without effect on sustained IgE production. This study shows that passive structural factors, including HV angle, do not appear to be significant correlates of foot pain intensity in HV. Estimated deaths and illnesses averted during fungal meningitis outbreak associated with contaminated steroid injections, United States, 2012-2013. Associated with these methods developments, a WHO Global Oral Epidemiology program was begun with the objective of facilitating comparison of data and their use in planning, replanning, and evaluating oral health services according to needs and economic possibilities. Unnecessary magnetic resonance imaging of hips: an economic burden to patients and the healthcare system.

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These data show the importance of timing of sequential ethanol injections for the induction of both tolerance and increased neural sensitivity. No significant differences were found in any brain area for GAD or GABA-T activity. The HIV infection epidemic contributed to the worldwide resurgence of the tuberculous endemic. However, the extensive killing observed in multicellular spheroids is consistent with release of a diffusible nitrogen mustard on reduction. A 45-year-old Japanese female presented with bullae and erosions on the trunk in December 1987.

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Colorimetric and thin-layer chromatographic methods for field assay of chloroquine and its metabolites in urine. The control law was applied to a 0.948 m3 fixed-bed anaerobic reactor treating raw and diluted (1:2) industrial distillery vinasses. Secondary shunting of hydrocephalus may be considered if intracranial pressure remains high despite adequate cranial decompression. The findings have new implications for the current myoblast/cell transplant and gene transfer therapy research which may provide possible answers for muscular dystrophy in the future.

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Rabies infection in these three patients did not originate in the United States but resulted from exposures in Laos, the Philippines, and Mexico. No information concerning the control of gene expression post-natally has hitherto been available. To investigate this issue, we compared the roles of the left and right sides of the Xenopus embryo during the development of anatomic asymmetries in the digestive system. These results suggest that site of tail heating, time of day, and presence of ovarian hormones can influence tail flick latency independently, thus demonstrating the complexity of the mechanisms that may contribute to pain threshold even within the same paradigm.

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The current World Health Organization Classification of tumors of the Central Nervous System (WHO 2000) lists more than 120 types of brain tumors. Dendritic cells (DCs) are rare leukocytes that are uniquely potent in their recent application to therapeutic cancer vaccines. Induction of the intercellular adhesion molecule 1 (ICAM-1) on the surface of epidermal keratinocytes has been proposed as an important regulator of contact-dependent aspects of cutaneous inflammation.

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von Willebrand factor detects all of these lipids as well as several additional minor sulfated lipids. After measurement of the length of the outer opisthosomal setae of the male mites, they appear to be Psoroptes ovis (Hering), the common scabies mite of domestic sheep, cattle and horses. Attitudes of medical residents regarding intensive care for patients with the acquired immunodeficiency syndrome.

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This article discusses these findings and the molecular mechanisms that can now be addressed with the atomic structures. Both the observed and expected heterozygosities were higher in peripheral populations compared with the central populations. The SWD and the DWLD are similar in that both are intervention implementation roll-out designs. It is therefore not surprising that alcohol also represents the drug most frequently abused by persons on methadone maintenance.

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Intraperitoneal injection of a CRH antagonist, astressin (30 mug/kg), significantly attenuated the post-inflammatory visceral hypersensitivity on d 7. The effect of total phenolic compounds on cell apoptosis due to hydrogen peroxide-induced oxidative damage was detected by Hoechst 33258 and Annexin-V/PI staining using fluorescence microscope and flow cytometry, respectively.

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Traction of the breast makes possible a dynamic study of the organ and its coverings. Dissociation of covalent protein adduct formation from oxidative injury in cultured hepatocytes exposed to cocaine.

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Segregation rates of SA11 RNA segments 1, 5, 8, 9 and 11 were significantly different as compared with those previously reported in the in vivo experiment. ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-beta peptide (1-40) at the blood-brain barrier.

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A 10-year appraisal of cesarean delivery and the associated fetal and maternal outcomes at a teaching hospital in southeast Nigeria. Patients were categorized as current smokers, former smokers, or never smokers, and then compared for their risk-adjusted likelihood of undergoing revascularization procedures (percutaneous coronary intervention or coronary artery bypass grafting) after cardiac catheterization.

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Quantitation of CSF concentrations and biological activity of probenecid metabolites. For modelling the distribution of paired survival variables, we may use a paired exponential survival distribution that is specified by the marginal hazard rates and a measure of dependency. An epidemiological association between veterinary and medical disease outbreaks was established following cases in a dairy unit, a poultry unit, a calf rearing unit and one pig and dairy unit (on the same farm). The present data lend credit to the hypothesis that endorphins are involved in some psychotic states in the human.

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In all patients with a preexisting nasogastric tube, the replacement by the decompression/enteroclysis tube was considered more comfortable by the patients. Self reported levels of knowledge and experience of illicit drugs. The aim of this study is to evaluate the efficacy and safety of interventional radiology procedures in the treatment of major urological complications after kidney transplantation. To benefit from the high spatial and temporal resolution of the respective dynamic MRI data sets, their analysis requires algorithms that are capable of both precisely delineating task-related activation patterns and demonstrating functional connectivity of interacting areas. The results analysed suggest that thrombinemia and POL interact as follows: activation of thrombinogenesis causes POL activation resulting in further thrombinogenesis activation etc.

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Previously published management recommendations regarding investigation and treatment have had little impact on intended practice. Disturbances in gut motor activity have been proposed as a characteristic phenomenon in patients with irritable bowel syndrome (IBS). When expressed per unit of dry mass, the enzyme activities tested, appeared to be independent of the type of amniotic fluid cell.

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Peer norms influence the adoption of behavior changes to reduce risk for HIV (human immunodeficiency virus) infection. Good growth was seen on concentrations of sulphate or thiosulphate as low as 10 microM.

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Modulatory rTMS over the left dlPFC may influence automatic emotion regulation capabilities by influencing frontal-limbic connectivity. It has been shown recently that neck muscle vibration in combination with an exploration training leads to lasting amelioration of spatial neglect. The technique of gas chromatography/mass spectrometry (GC/MS) was used to identify and quantify 16 pyrimidine- and purine-derived DNA lesions. Usefulness of pulmonary gammagraphy using 67Ga citrate in sarcoidosis Predicting postoperative atrial fibrillation using CHA2DS2-VASc scores.

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Following orchiectomy and retroperitoneal lymph node dissection (RND) 11 patients with non-seminomatous testicular cancer were treated alternately with combination chemotherapy consisting of vinblastine/bleomycin and adriamycin/cis-dichlorodiammineplatinum (II) (DDP). Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif. Density measurement on CT proved reliable in the differential diagnosis between recurrent disc herniation and postoperative scar.

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The explanation proposed (though without experimental proof) is that, during the restricted diet, the increased reverse triiodothyronine (rT3) would result in a decrease of the aerobic glycolysis and no change in the anaerobic glycolysis. Androgen modulation of multiple transcription start sites of the mitochondrial aspartate aminotransferase gene in rat prostate. Intra-articular substitution of the anterior cruciate ligament by flap transfer of the iliotibial tract using the Insall technic

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For both substrates, take-off frequency increased with wind speed. Providing culturally sensitive care to the childbearing Islamic family: Part II.

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The six investigated diterpenes were applied to the model and their activities against PC-3 cells were calculated. Implementation of a criteria-based antimicrobial formulary system.

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There was no difference between the efficacy of DNA repair in the infected and non-infected cells after treatment with hydrogen peroxide and amoxicillin. Measuring greatest tumor dimension is a simple, inexpensive predictor of PSA failure in men who have undergone radical prostatectomy. Attitudes toward genetic testing among the general population and relatives of patients with a severe genetic disease: a survey from Finland. Many studies identify inappropriate laboratory use based on implicit or explicit criteria that do not meet methodological standards suggested for audits of therapeutic maneuvers.

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c-met seems to influence the development of vascular invasion via an unknown mechanism. Polytetrafluoroethylene (e-PTFE) membranes and titanium membranes were used to cover the defects around implants. The relative phase between movements of adjacent segments is similar when the body is in S shape (i.e., when walking forward), or C shape (i.e., when turning). We present a case of a 36-year-old woman with known pelvic leiomyomatosis with metastasis to the tricuspid valve. Pulmonary arteriograms were abnormal but none showed evidence of pulmonary embolism.

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Ten patients were operated with the diagnosis of unilateral nerve root compression secondary to facet degeneration. Multilevel multivariable regression models were used to examine the effect of patient and surgical factors on implant survival, patient-reported outcome and satisfaction at 6 months and 8 years following UKR. A haemorrhagic dermatitis develops, which may progress to necrosis. Studies in bacteria and bacterial viruses have led to methods to manipulate and recombine DNA in unique and reproducible ways and to amplify these recombined molecules millions of times. Studies of the antibacterial effect of the scandium complex of enterochelin.

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Using Fink-Heimer silver staining, axonal degeneration was detected in the neostriatum and the dorsal agranular insular cortex and degenerating pyramidal cells were observed in portions of the somatosensory neocortex in both strains. Suicide by jumping in Singapore as a function of high-rise apartment availability. Compressive strengths ranged from 48.6 MPa to 307.1 MPa, and diametral tensile strengths from 5.8 MPa to 34.8 MPa. Azatioprine intolerance is the principal indication for mycophenolate use but it can be used as a front-line therapy. To determine if a period in a research job improves confidence in research skills and to assess the quality of research training.

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A comparison of planar scintigraphy and MRI in the screening of skeletal metastases The obtained sulfamethazine (SMZ)-imprinted polymer showed high affinity and selectivity toward SMZ and other structurally related sulfonamides in acetonitrile or water-acetonitrile mobile phases, particularly in high aqueous systems. Tooth defects were more frequent (2.5 times) and severe in Aborigines than in Caucasians. Prior to reconstruction, several geometric and densitometric imaging errors are corrected.