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Rapid mapping of repeated DNA sequences to chromosomes by PRINS and cycling-PRINS. Selective medium that distinguishes Haemophilus influenzae from Haemophilus parainfluenzae in clinical specimens: its value in investigating respiratory sepsis. Enzymatic activity of the oral mucosa in an experimental gastrointestinal lesion Setting Spacecraft Water Exposure Guidelines (SWEGs) for lead (Pb) in spacecraft drinking water has special challenges related to estimating the increase in blood lead levels (PbB) due to the release of lead to systemic circulation via microgravity-induced bone loss. No decrease in the level of DNA or protein benzo(a)pyrene-derived covalent binding was observed in any of the tissues studied.

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Collectively, these data support the role of METex14 alterations as drivers of tumorigenesis, and identify a unique subset of patients likely to derive benefit from MET inhibitors. IMP (Integrative Multi-species Prediction), originally released in 2012, is an interactive web server that enables molecular biologists to interpret experimental results and to generate hypotheses in the context of a large cross-organism compendium of functional predictions and networks. The natural history of HIV infection in women attending a sexually transmitted disease clinic in Dublin.

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These findings suggest that N-glycosylation may be involved in the secretory mechanism of the mucin-related product. The organization of the human-plasminogen-activator-inhibitor-1 gene. Mechanisms of voice production are reviewed, as well as common laryngeal pathology effecting voice production.

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The association of myasthenia, thymoma and ganglioneuroma of the sella turcica is unknown. Regarding the application of the deformable models theory, implemented in the context of an expert type software environment, it is known that the fact that modelling by advanced methods and techniques based on the deformable surfaces theory increases the efficiency of the dentofacial prosthetics procedures is a domain of great interest in the actual medical research. Such genetic polymorphisms may result in inter-individual differences in detoxification of certain chemicals, and as a consequence, possibly affect health-risk assessments. complex carbohydrates on VLDL secretion rates and HDL metabolism in the guinea pig.

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Contrast media injection in the rat after multiple renal insults. The SAINT group had fewer site adhesions, faster healing, less foreign body reaction, and fewer lymphocytes than the control group. Experience in mass Papanicolaou screening and cytologic observations of teen-age girls. All patients with a transsphincteric fistula and a limited number of anterior intersphincteric fistulas in female patients were registered from July 1(st), 2010 until November 30(th), 2012.

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We used realistic shark models to examine how altering predatory behavior and morphology (size, speed and approach orientation) influences escape behavior and performance in Squalus acanthias, a shark that is preyed upon by apex marine predators. The level of tRNA methylation in vivo is also higher during regeneration. The mean urinary excretion of calcium, magnesium and oxalate was unaffected by the treatment, although six of eight patients with a pre-treatment oxalate excretion above 25 mmol per mol creatinine demonstrated lower urine oxalate values during the treatment. Evaluation on the use of confined liquid impinging jets for the synthesis of nanodrug particles.

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The purpose of this study is to compare the incidence of acute renal injury (ARI) in patients on intermittent infusion to extended infusion piperacillin/tazobactam. NMR is able to demonstrate pancreatitis and pancreatic pseudo-cysts. Supernatants from cultures of unstimulated guinea pig thymocytes were investigated on allogenous thymocytes as regards conditioning effect. An original technique was used to study the growth pattern of cells of varying origin on limited areas (from 1 to 0.01 mm2).

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Fluorescence labeling can be used in studying protein sorption on various surfaces with a sensitivity of about 10(-8) g/cm2, commensurate with radioactive labeling. At the end of this 4-month period, the ligatures were removed, and an apically positioned flap procedure was performed.

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Untouched GMP-Ready Purified Engineered Immune Cells to Treat Cancer. We identified a functional coupling between L-type voltage-gated calcium channels and RyRs and identified RyR3, a subtype enriched in area CA1, as the specific isoform required for superoxide-induced potentiation.

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Subsequently, the tooth was extracted, and it was only after the extraction site failed to heal that a biopsy was performed which confirmed a metastatic lesion. Additional inputs-including extension activities-are therefore required to improve the effect of the programme in the winter and in the neonatal period. Striatin family members have been associated with diverse physiological functions.

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Recently, we reported the construction of a cDNA library encoding a heterogeneous population of polyadenylated mRNAs present in the squid giant axon. All tested nootropics exhibited a dose-related reduction in immobility. Using the same set of individual flies from each of several populations, we show that the use of different primers in the RAPD method permits detection of different levels of population differentiation. Km for reductase is approximately the same for the hydroxylase activities (0.4-0.6 microM) and for the lyase activities (1.7-2.0 microM) of the two enzymes.

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In the diagnosis of malignancy, pleural fluid cytology was superior to pleural biopsy. An abnormal echo texture was seen in all cases: focal hypoechoic nodule (about 1 cm) in two, diffusely hypoechoic in one, and mixed diffuse/focal abnormality in one.

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The synthesis of 2-acetamido-1,2-dideoxynojirimycin (2-acetamido-1,2,5-tri-deoxy-1,5-imino-D-glucitol) by a double inversion procedure starting from 1-deoxynojirimycin is reported. Gradation of lectin was done by stacking agarose gel blocks with increasing concentrations of lectin (discontinuous system) and by keeping the plate in a moist chamber at 4 degrees C overnight (continuous system) before electrophoresis.

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The inhibitory capacity of these antisera was removed by absorption with B10.D2 but not with B10 lymphocytes. solium cysticerci fractionated by isoelectric focusing and serum samples from patients with NCC, alveolar (AE) or cystic echinococcosis (CE), and other diseases. To investigate the effect of GRWD1 on chromatin architecture, we used formaldehyde-assisted isolation of regulatory elements (FAIRE)-seq or FAIRE-quantitative PCR analyses, and the results suggest that GRWD1 regulates chromatin openness at specific chromatin locations.

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Treatment of colorectal hepatic metastases by intrahepatic chemotherapy alone or as an adjuvant to complete or partial removal of metastatic disease. The isolates appear to be variants of the same new virus, for which the name Girard Point virus is proposed. The SF73 substitution appears to identify an activating region of FNR that is important for transcription activation at promoters that differ in architecture.

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Intracellular transport and compartmentalization of chromatin receptors and thyroid hormones The inability to find an effect of vasopressin in this study is contrary to results of other studies. Numbers of deaths from various cancers and cardiovascular diseases attributable to COC use. The pediatric optometrist is particularly well suited to manage this postsurgical treatment of patients with congenital cataracts. Diagnosis was confirmed by histopathology in three patients and by culture in the other three.

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Myocardial adrenergic changes at two stages of heart failure due to adriamycin treatment in rats. Pharmacologic and supra-pharmacologic doses of hydrocortisone acetate did not effect ultrastructural alteration of chondrocytes in articular cartilage of mature rabbits. This study suggests that conformationally constrained and dimeric peptides derived from antibody hypervariable loop sequences can bind antigens (including receptors) with reasonable affinity. Reliability of urinary monoamine and metabolite output measurements in depressed patients. DUP-1 holds promise as a lead peptide structure applicable in the development of new diagnostic tracers or anticancer agents that specifically target prostate carcinoma.

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We also found that after some 10 cycles of the stimulating alternating current the steady-state seemed to be established. Carboxymethyl cellulose (CMC) is one of the most widely used thickening agents in industry.

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Observed enurotoxic effects of both moulds were identical in most respects. Lysine-based structure responsible for selective mannose phosphorylation of cathepsin D and cathepsin L defines a common structural motif for lysosomal enzyme targeting.

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The fall efficacy was significantly lower in participants who had experienced falls than those who had not. Variation of the hydration level of human serum albumin caused by the variation of temperature and protein concentration is described.

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A protease which selectively cleaves this bond and produces the natural circulating peptide was identified in the particulate fraction of rat atrial homogenate and was solubilized by 1.6 M KCl. Effects of low-dose oral and transdermal estrogen replacement therapy on hemostatic factors in healthy postmenopausal women: a randomized placebo-controlled study.

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Through candidate and genome-wide association studies approaches, many gene polymorphisms and clusters have been implicated in drug, food and behavioral dependence linked by the common rubric reward deficiency syndrome (RDS). Aboriginal deaths in custody have become an issue of national concern and international attention. Urologists involved in the management of children with myelodysplasia and neurogenic bladders should be alert to this renal complication. Localization of intraocular foreign bodies by computed tomography. We present evidence to show that preferred listening levels vary with changes in the listening environment, especially when the signal-to-noise ratio is favorable.

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Short-term exposure of cells to low concentrations of glutamate desensitizes cells to a subsequent challenge from glutamate. The RMAT would be easy to perform as a screening test in a routine serological laboratory. The current use of tuberculin skin testing in pediatric practice. Prevention of MHC-alloimmunization by UV-B irradiation in a murine model: effects of UV dose and number of transfused cells.

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Interestingly, during followup rheumatoid and gouty phases alternated, without simultaneous manifestations of both diseases. The size and variability of the increase were similar to the expected difference between oesophageal and pleural pressure fluctuations occurring in the supine patient. The biomechanical tests revealed that bicortical osteosynthesis was superior to monocortical in the rigidity of the fixation. Theoretical studies on the effect of extinction and recolonization upon genetic variance started appearing in the 1970s, but the role of local adaptation still has no good theoretical basis.

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Selective colchicine antimitotic suppression of the early phase of hepatocellular division and tissue repair induced by a low dose of CCl4 results in progression of toxic liver injury, leading to hepatic failure and mortality. The aim of this study was to determine whether IVC filters affect the outcome of lower limb flap reconstructions in the trauma patient. Identification of Allorecognition Loci in Neurospora crassa by Genomics and Evolutionary Approaches.

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The results suggest a northern and southern division of the B.6 subclade B.10, where B.11 predominates in Western and Central Europe and B.70 is found in Fennoscandia. Different carboxyl-terminal domain kinase activities are induced by heat-shock and arsenite. The monitoring conducted in 2006-2008 demonstrated that warm, subtropical climate and low- to moderate salinity of water in the Black Sea coastal zone provides a favorable environment for growth and spread of V. The objective of this study was to assess the in vivo fate of poly(2-(dimethylamino)ethyl methacrylate) (pDMAEMA)-based polyplexes after intravenous administration into mice. The somatomedin activites in serum and lymph have identical elution volumes on Sephadex G-50 in 1N acetic acid.

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We used voxel-based morphometry to characterize the structural correlates of psychopathy in a sample of 35 healthy adults assessed with the Triarchic Psychopathy Measure. 41 specimens contained single serotypes, while 51 were double infected, 12 specimens harbored 3 different serotypes of Salmonella, 6 specimens contained four and 2 contained five different serotypes. The societal economic burden of herpes zoster in Sweden is not well described today. In the first approach, DTPA groups were attached directly to purified fragment E1,2. The existence of cervical neoplasia in women with human immunodeficiency virus (HIV) represents one of the most serious challenges in the oncologic care of immunosuppressed patients.

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Increasing the density of the soft agar did not influence the frequency of A/B colonies. A major advance in the last decade has been the introduction of the novel agents thalidomide, bortezomib, and lenalidomide as part of front-line treatment in both the transplant and nontransplant settings. In 26 cases the intraarticular bleeding was caused by patellar dislocation. A brief history and summary of studies designed to elucidate the role of monoamine oxidase (MAO) in schizophrenia are presented. Hence, having two distinct mechanisms for hypothermia damage is not unique to the Chinese hamster cell line.

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Videokymography visualizes small left-right asymmetries, open quotient differences along the glottis, lateral propagation of mucosal waves, and movements of the upper margin and, sometimes in the closing phase, the lower margin of the vocal folds. Characterization of the stilbenedisulfonate binding site on band 3. We report a case of an infected aortic pseudoaneurysm, seen as recurrent septicemia, during the first 6 months after cardiac transplantation.

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In an attempt to study the gene products of the HLA complex, a monoclonal antibody, named HU-30, was produced by immunizing BALB/c mice with a cultured human B lymphoblastoid cell line, Shi-C3 (Aw24, Aw31, Bw51, Bw52, DR2, DR blank, MT1, MT2, MB3). Here, we present for the first time the proteomic analysis of hepatocytes (Huh-7 cells) infected with DENV-2 by label-free LC-MS. The Km for NADPH at an initial nitrobenzene concentration of 0.1 mM is 183 microM. Do asthma patients in general practice profit from a structured allergy evaluation and skin testing?

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The complete amino acid sequence of chitinase-a from the seeds of rye (Secale cereal). Thus, Plk1-mediated phosphorylation of Celsr1 ensures that PCP redistribution is precisely coordinated with mitotic entry.

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Origin of NK cells, their morphological characteristics, location, genetic control and the methods of evaluation of their activity It was therefore possible to visualize vasopressin- or CFR-IR and nuclear glucocorticoid receptor-like-IR simultaneously.

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We interpret these data as showing that the epitheliocyte attempts to override the guiding influence of anisotropic substrata. Human salivary acidic proline-rich proteins (PRPs) constitute a significant fraction of the total salivary protein and possess important biological activities.