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Plavix (Clopidogrel)
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Clopidogrel

Plavix is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. Plavix is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral arterial disease, It has been shown to be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and provides additional benefit to patients with acute coronary syndromes already taking aspirin. Plavix was granted FDA approval on 17 November 1997.

Other names for this medication:
Clopidogrel, Plavix, Anclog, Anlet, Antiplar, Artevil, Clavix, Clopicard, Clopilet, Clopivas, Deplatt, Diloxol, Duoplavin, Expansia, Farcet, Globel, Grepid, Iscover, Karum, Klopidogrel, Nabratin, Narutis, Nefazan, Noklot, Pidocar, Pidogrel, Pladex, Plagerine, Planor, Tisten, Troken, Trombex, Vaclo, Zyllt,

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Organ distribution of 3-hydroxy-3-methylglutaric acid, a potential anticholesterolemic agent. Four 3 beta-hydroxy-delta 5-steroid sulphates were found to be potent and specific inhibitors of the sperm acrosomal proteinase, acrosin. Resin casts replicate the internal structure of organs and provide a three-dimensional representation of the arrangement of vessels and intercellular spaces. These enzymes are believed to act via ATP-dependent binding of AMP to their substrate. Without a broader interpretation of this regulatory requirement in NBS research for which there is evidence of a clinically meaningful benefit from treatment, we may create incentives for the implementation of inadequately evaluated NBS tests.

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A review of IMD, criteria for establishment of the diagnosis, initial management, rationale for the surgery, type of surgery, and postoperative results in twenty-three cases will be discussed. Ventricular LPs are of limited use for risk stratification in unselected post-infarction patients in the modern reperfusion era.

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Free amino-acids in the fetal and maternal compartments towards the end of normal and pathologic pregnancies were examined with gas chromatography. Glass adherent cells were able to phagocyte the latex particles.

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By contrast the luteinising hormone levels rose (p less than 0.01) within 3 days of administration of the steroid. However, the subjective component in these symptoms is so great that the objective criteria cannot be satisfactory. Regeneration could also take place in the medium used to produce protoplasts, but the process was different in many details. We show that in fission yeast redundant casein kinase 1 homologs, Hhp1 and Hhp2, previously shown to regulate segregation via phosphorylation of the Rec8 cohesin subunit, are also required for high-level meiotic DNA breakage and recombination.

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With an assay that quantitates the transfer of 6-thioguanylic acid from hypoxanthine phosphoribosyltransferase (IMP:pyrophosphate phosphoribosyltransferase, EC 2.4.2.8)-positive donor cells to negative recipient cells through gap junctions, differences in contact-mediated communication between normal and transformed human cells in culture have been detected. A unique combination of Dyke-Davidoff-Masson syndrome and Down syndrome: Diffusion tensor tractography findings. In patients, inactivating mutations cause osteopetrosis, and gain-of-function mutations cause osteopenia.

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It is anticipated that formal clinical trials could be conducted in the near future to determine the efficacy of continuous LHRH agonist administration. Despite improvements in function, gait speed, and TUG outcomes remained below clinically important thresholds, indicating patients were limited in community ambulation and at risk for falls. The larval stage (cysticercus) has been found before only rarely in humans or primates.

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Desmosomal cadherin misexpression alters beta-catenin stability and epidermal differentiation. To evaluate the efficacy of herbal medicines for the treatment of allergic rhinitis (AR). The safer and more common use of phenol infiltration at the peripheral nerve level is now more accepted for brain injury and spinal cord injury patients. The reasons behind the decline in release of alpha-ANP may be atrial compression by the distended lungs and the well-known reduction of venous return to the heart.

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Experimental comparisons of different plethysmographs are described and the requirements for future development of these devices are defined. The 38 year old women had on an average 2.1 teeth more in 1980 compared to participants of the same age 12 years earlier. A significant difference was found in the age at onset of epistaxis (median 11 yr) and of gastrointestinal bleeding (median 55.5 yr). Body weight and toxicological observations did not show any untoward response.

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Blood lactate, pyruvic acid and serum creatinine kinase were at high levels. The alterations in inter-hemispheric functional coordination of patients with panic disorder: the findings in the posterior sub-network of default mode network.

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Src tyrosine kinases represent an important signaling element in angiotensin II-induced endothelin production in small arteries in vivo. Magnetic resonance angiography showed that a branch of the middle genicular artery extended to the upper side of the graft through the posterior capsule and that branches of the inferior genicular artery ended at the lower side of the graft in all patients. Clustering of conservative amino acid sequences was found in each patient. Membrane potential changes, membrane receptor analysis, membrane fluidity, and analysis of the effects of the preparative techniques.

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Chondroitin-6-sulphate and chondroitin-4-sulphate proteoglycan were increased in Turner syndrome fetuses and BGN seemed to be underexpressed compared with normal controls, while DCN was not. To elucidate the mechanism of this hormonal interaction, the present study examined the effect of PRL on cytosol and nuclear androgen receptors in the three prostate lobes. These observations strongly suggest that EGF does not act as a primary cue for inducing developmental changes in suckling mouse small intestine.

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There was no difference in mean CV between smokers and the patients who had large RV but no airway obstruction, although both groups had higher mean CV than ex-smokers. One strain specific mAb was obtained reacting only with the non-invasive strain iB1. Schizophrenia rates were obtained from a British Columbia coastal Indian group numbering 14 000.

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Evaluation of Etest for rapid susceptibility testing of Mycobacterium chelonae and M. The U1 ribonucleoprotein appears to be the component of extractable nuclear antigen characteristically reacting with sera from patients with mixed connective tissue disease. The position of the repetitive sequences suggests that they arise during replication both near the origin of replication and at the site of termination of the D-loop strand. The two principal fluoride rinsing methods, low potency / high frequency and high potency / low frequency, are described.

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Contract housekeeping: hospital survey cites reasons for termination. Unlike enzymatic methods, gold particles have less tendency to obscure ultrastructure. We report temporal swallow measures, physiologic variables, and swallow safety of upright and supine swallowing in healthy subjects using videofluoroscopy (VFS).

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Substrate specificity of ARNO-like GEFs for ARF1 depends solely on the Sec7 domain. A common statistical challenge in the analysis of library sequences is to infer whether there is differential expression for the same transcript under two different conditions, such as normal and diseased tissue. Human fallopian tube mucosa is a novel source of multipotent cells. These cells seem heterogeneous with respect to size, cell surface, granules maturity and morphology of nucleus using transmission and scanning electron microscopy. Three hypotheses were tested: 1) Duration experience will be shorter for decoded light than for coded heavy auditory information.

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VASP phosphorylation at serine157 may be an important component underlying the synergistic inhibition of human platelets by cGMP-and cAMP-elevating agents. Effect of hypoxia and short-term fasting on the plasma acetoacetic acid level in rats of different ages. Flufenamic and tolfenamic acids inhibit calcium influx in human polymorphonuclear leukocytes. Acute nephropathy after contrast agent administration for computed tomography perfusion and computed tomography angiography in patients with acute ischemic stroke.

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Acetylcysteine in the oral mucolytic treatment of cystic fibrosis. Genome-size stability of the clones was assessed by flow cytometry. Sphingomyelin is a phosphosphingolipid that accumulates in patients with Niemann-Pick disease. A continuous time (analog) processor that will accomplish this task is described. Treatment outcome, which was evaluated primarily in terms of the occurrence of major depression or manic episodes, was significantly related to characteristics of the index episode, ie, the episode that brought the patient into the study.

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Long-term stability of allozyme frequencies in a wood lemming, Myopus schisticolor, population with a biased sex ratio and density fluctuations. The presence of a significant positive correlation is taken as evidence of a negative feedback loop between the hemispheres. With feedback, the rate of decrease in error over sessions was similiar for both levels of IQ. This technique is indicated in pulmonary embolectomy or to dispose of a vena cava clot prolapsed into the right cardiac cavities. Furthermore, the number of oral lesions found in the present study are higher than reported in other strains of rats following administration of NMU.

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Comparatively little is known about the genetic requirement and mechanisms underlying the formation and separation of germ layers by morphogenetic movements during gastrulation. Cr-TrHb1-1 and Cr-TrHb1-8 have been postulated to be parts of the nitrogen assimilation pathway, and of a NO-dependent signaling pathway, respectively. Among other mineral nutrients, K, Ca and Zn concentrations decreased, while P, Mg, Cu, Fe, Mn and B concentrations did not change. Horseshoe lung in an infant with recurrent pulmonary infections. Younger age at the beginning of treatment was not found to be predictive of a better outcome after the first treatment.

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Role of arterial chemoreflex in breathing during sleep at high altitude. In the present work we report on investigation of affecting of duckweed (Lemna minor) by various doses of cisplatin (0, 5, 10, 20, 40, 80 and 160 microM) for 4 days.

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Effects of topical antimicrobial agents on the human neutrophil respiratory burst. Adipocytes, one of the major components of the breast microenvironment, have been shown to provide pro-tumorigenic signals that promote cancer cell proliferation and invasiveness in vitro and tumorigenicity in vivo. Use of ultrasonics in the overall treatment of temporomandibular joint diseases Interferon, when given or induced 24 hours before contact of mice with sheep red blood cells, prevented sensitization, and no delayed-type hypersensitivity reaction could be elicited 4 days later, after challenge with the antigen, as shown by the absence of footpad swelling in treated animals.

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We retrospectively analyzed 182 patients who underwent CIESI from January 2009 to December 2012. The ELISA-spot assay was used to enumerate individual Ig-secreting splenic B cells and determine the proportion of these cells producing antibodies reactive with each of six autoantigens and two conventional Ag. Release and elimination of 14C-fluphenazine enanthate and decanoate esters administered in sesame oil to dogs. Human monkeypox, an emerging viral zoonosis first recognized in Africa, has recently emerged in the mid-western US. After oral glucose, cumulative blood glucose and insulin were significantly lower in SSV than in controls, whereas in HSV, both parameters tended towards lower values.

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By selectively choosing different diuretics or diuretic combinations, the clinician can achieve the desired diuretic effect and prevent many of the electrolyte and acid-base derangements that accompany diuretic therapy. To determine whether accelerated telomere shortening could explain chromosome instability and assess the effect of drugs and smoking on telomere dynamics in these cells.

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Since one cause of nephrotoxicity can be assumed to be intrarenal accumulation of gentamicin, it may be concluded that a deficient ability to concentrate aminoglycosides in the kidneys resulted in decreased nephrotoxic potential of gentamicin in the young rats. Therefore, a reflex mechanism appears to be involved in vomiting induced by caerulein. The retention time of hypothalamic CRF-41 during high-performance liquid chromatography was identical to that of synthetic rat CRF-41 at all stages investigated.

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Lamina terminalis fenestration diminishes the incidence of shunt-dependent hydrocephalus and, combined with extensive cisternal blood cleansing, can lower the incidence of stroke. Investigation of variation of the production of biological and chemical compounds of Hyssopus officinalis L The alkylating agent IDAM bound to cellular macromolecules and depleted cellular non-protein thiols almost completely by 1 h, while LDH release occurred first at 2 to 3 h.

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The importance of passive immunity for the prevention of the disease in growing animals is discussed. In this report we analyze the results and morbidity in patients undergoing fine-needle aspiration before neck reexploration. Induction of an antigen-specific immune response and partial protection of cattle against challenge infection with foot-and-mouth disease virus (FMDV) after lipopeptide vaccination with FMDV-specific B-cell epitopes.

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Since the cell cycle is irreversibly arrested in SIPS-induced cells, even if they are stimulated by various growth factors, it is thought that SIPS is a form of cell death, irreversibly eliminating replicating cells. In a field study we found that non-ovigerous females distributed throughout the water column preferred the deeper parts. The same cells produced high levels of procoagulant when incubated with tuberculin or lipopolysaccharide.

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The purpose of this study was to examine the independent contributions of physical performance and cognitive status to subsequent levels of ADL disability in low-functioning non-institutionalized older adults. The effect of magnetic fields on scar formation of experimental wounds The compounds were extracted from acid-treated body fluids into chloroform--1-pentanol (3:1) and re-extracted into a small volume of an aqueous phase at Ph 7, which was injected into the chromatographic column.

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In the persons living temporarily in high-altitude areas it was more pronounced at a single administration of nitroglycerin and in the native inhabitants of the mountains--during course treatment with nitrong. The stages covered were admission, initial modality of service, service delivery in terms of types and amounts of services rendered and termination. By 2-D isoelectric focussing/SDS polyacrylamide gel electrophoresis the tektins separate into several polypeptide spots.

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An investigation into the source of the deglutamated metabolites of methotrexate in patients treated with high dose infusions. Recycling of EGF was found to occur rapidly after internalization at 37 degrees C. Cytokines, bone remodeling, and estrogen deficiency: a 1998 update. Two protein bands at about 36 kDa and 27 kDa were specifically labeled on antigen-presenting cells but not on helper T cells. When renal artery stenosis coexists with contralateral intrinsic renal disease preservation of functioning renal parenchyma is an important goal of therapy.

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Alkaline phosphate activity was significantly raised (393 U/l) and parathormone level reduced (7 ng/l). Two patients with apical lesions on maxillary central incisors showed large osseous defects of the residual ridge. The two N-linked glycosylation sites present in this N-terminal portion of the viral SU were removed by site-directed mutagenesis without disturbing its biosynthesis and incorporation into infectious virions. Six hours after radiation therapy, shrunken cells appeared scattered throughout the tumor, but they were not detected by ultrasound. In contrast to the well-characterized primary response of mouse mammary tumor virus, in vitro transcription assays in isolated nuclei show that the rate of transcription of the AGP gene is high even in the absence of hormone.

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Solitary plasmacytoma of bone: fourteen years disease-free survival. The authors recommend that these messages be conveyed to elderly patients before surgery.

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Diagnostic accuracy of the Whooley depression tool in older adults in UK primary care. We conclude that PSP is synthesized throughout the nervous system and that it is presumably of both astroglial and neuronal origin, in contrast to GDNF and neurturin, which seem to be predominantly of neuronal origin. The suggested mechanism involves modulated secretion of growth factors, cytokines and altered regulation of AMPK and SIRT1 that converges on mTOR inhibition.

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Descriptive analysis of data obtained by personal interview, laboratory investigations, and clinical examination by a trained nurse. These incorporated Manchester reagent, Recombiplastin, IL PT Fibrinogen HS Plus, Manchester combined capillary prothrombin time reagent, and a freeze dried in-house reference rabbit brain thromboplastin, RBT 1010. Quantification of nephrotoxicity in rabbits by automated morphometry of alkaline phosphatase stained kidney sections. Technology will enable the military to expand the scope and nature of optometry services through automation.

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We studied 38 infants with a history of coughing and wheezing who had pulmonary function tests performed within two weeks of their diagnosis of tinuvin 400 molecular weight swallowing dysfunction. AAD patients showed significant disturbances in faecal SCFA pattern. 2-Methyl-5-(3-phenylpropionyl)-1-benzoxolane (CAS 159264-96-7) was synthesized and studied for anti-inflammatory properties.

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Antibiotics contribute significantly to the management of the surgical patient. ucerax dosage calculations More recently several assays using transgenic animals have been developed. Immunochemical analysis of the synthetic peptides incorporated into the protein antigenic determinant of the potato virus X coat

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Flavonoids and their glycoside derivatives were found to be good substrates, whereas phenolic acids were either poor or nonsubstrates. The advantages compared to the selective needle biopsy, the transthoracic circumscript fixation and the lung fixation organ ciproxina suspension bayer removal are: 1. The significance of changes in lactate dehydrogenase activity for the diagnosis and effective treatment of nephroblastoma in children Prediction of quality of life in a cohort of end-stage renal disease patients.

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Proximal muscle weakness in severe lead poisoning from retained bullet fragments. paroxetine 20 mg generique Eruptions caused by poison ivy (see Cover) and related plants are almost always a form of allergic contact dermatitis. Long-standing HCV can progress to cirrhosis, which can contribute to significant morbidity and mortality.

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mutans from the small intestine suggests that the disparate results obtained from experiments in which this organism was used to immunize monkeys orally, are not attributable to the prior colonization of such an immunologically important region. An esophagectomy performed by thoracoscopy and laparoscopy techniques is feasible, however, such an esophagectomy combined with a systematic lymphadenectomy may not qualify as minimally invasive because of the equivalent morbidity rates to an open radical esophagectomy. A pentapeptide within the nonapeptide sequence was found to reduce the formation of lung colonies in mice injected with melanoma cells and also to inhibit the invasiveness of the voxin combo tablet i cene cells in vitro.

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The polyspecific cation transporter rOCT1 in the rat was the first identified member of a new protein family with 12 presumed membrane-spanning alpha-helices and two large hydrophilic loops. Bovine and equine superoxide dismutase do not show spectral or chemical evidence for such a group. In contrast, the rapid appearance of cardiovascular derangements after interruption of maternal uterine circulation in embryos with unclamped umbilical cords emphasizes the idea that even brief intervals of uterine ischemia are deleterious to the rabbit embryo. Human histocompatibility antigen mutants immunoselected asec mimosas vs kaiser chiefs wiki in vitro.

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Lung function can be restored only if the epithelial layer is restored. Experimental ventricular preexcitation type WPW was performed in five dogs, through an artificial bypass, an electric conductor, made of copper, with a diameter of 8 mm and 12 cm in length. One of them was physically and functionally indistinguishable from transcription factor IID (TFIID or BTF1), a pivotal component of omeprazole delayed release 20mg polymerase B transcription complexes, which binds to the TATA element.

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Here we describe the genomic organization of the AP-2 gene including an initial characterization of the promoter. A one-year statistical analysis of dental emergencies in a pediatric hospital. To investigate whether concomitant EE exposure could prevent the reinstatement of ethanol-induced CPP, one half of the mice were housed in standard environment (SE) and the other half in EE during the extinction and reinstatement session in the second withdrawal syndrome after discontinuation of venlafaxine 75mg experiment. This results in changes to their surface receptors to activate phosphorylation cascades that lead to differential activation of signalling pathways such as those involving osteopontin and sonic hedgehog. Both peptides were conjugated with aaPEG (average molecular weight, 3,000) to prepare a bifunctional peptide-PEG hybrid.

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Two patients have been studied who have presented with the characteristics of methanol poisoning--metabolic inpro electric usa acidosis and ocular toxicity. Isolation and identification of viruses from clinical specimens at the National Taiwan University Hospital during Jan. Therefore, we suggest that in wheat-germ, cell-free translation systems G-418 affects the 80 S ribosomes and inhibits the elongation cycle.

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Activity of some nuclear enzymes associated with DNA repair following hepatocarcinogen administration to rats. Calcitonin gene-related peptide in medullary thyroid carcinomas: characterization of pantoprazole 20mg otc molecular forms including the amidated C-terminus. The major peaks of thymocyte stimulatory factor activity and T cell growth factor activity cochromatographed in the various systems used, but T cell growth factor activity without significant thymocyte stimulatory factor activity was sometimes present.

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This study sought to define the clinical characteristics, distribution of mutations and phenotypic bactrim dose mrsa cellulitis presentation of patients presenting to our center with hereditary ATTR amyloidosis. Pericardial tamponade as a lethal complication following dilatation of aortic valve stenosis The conformation of a B-DNA decamer is mainly determined by its sequence and not by crystal environment. The signals transmitted by both hormones are therefore ambiguous. In simian virus 40 (SV40) DNA replication, RPA containing either of these mutants functioned as efficiently as wild-type RPA.

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The CM of sensitive M1 cells, which could be induced to differentiate into macrophage-like and granulocyte-like cells by various factors stimulating the differentiation (D-factor), slightly inhibited colony formation of normal bone marrow cells by colony stimulating factor (GM-CSF). Both verapamil and diltiazem significantly enhanced urinary sodium excretion with no effect on either urine volume or potassium excretion. This work is the first demonstration of electrical modulation of surface energy to reversibly switch dynamic high-speed gas-liquid two-phase microfluidic flow patterns. Role of HCN channels in the nervous system: membrane omapro prescribing information excitability and various modulations In a Black/White discrimination, in which the stimuli were restricted to the goal-arm walls, the irradiated rats were handicapped in the acquisition (low task difficulty) and reversal (moderate task difficulty) phases of the task.