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The effects of incubation in EDTA, colchicine or cytochalazin B were also studied. Persistent vaginal estrus and serum hormones after chlordecone (kepone) treatment of adult female rats. In this study, therefore, we wanted to investigate the possible value of the proinflammatory cytokines interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) measured in bronchial lavage fluid (BLF) in predicting functional outcome of the pulmonary graft after reperfusion. Nucleotide sequence of the Clostridium stercorarium xynB gene encoding an extremely thermostable xylanase, and characterization of the translated product.

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A matched-group comparison of 15 women in each sample suggests that the two groups do not differ in overall intelligence, although lesbians, unlike female transsexuals, tended to have a significantly higher verbal IQ than performance IQ. The spectral analysis of the radioactivity counts taken in different region of interest, showed evidence of a periodic fluctuation, with a period value around 1 minute.

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The nucleolus showed spontaneous segregation of its components due to temporary inactivation of the ribosomal genes. Seventy per cent of the patients who were followed, on the other hand, showed consecutively negative cytology and pathology after cryosurgery. First, pretreatment of the isolated mitochondria with an anti-VDAC antibody specifically prevented As(2)O(3)-induced cyto c release. Low dose exposure to nicotine during adolescence enhances the reinforcing effects of METH, while heavier exposure has no effect on METH intake.

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pumilus chromosome, but from different regions, as shown by Southern hybridization and the analysis of restriction fragments. A detailed case history of lead poisoning in a young infant is presented. In canines, neoosteogenesis does occur in mandibular autografts exposed to two consecutive freeze-thaw cycles prior to reimplantation.

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Common and divergent peptide binding specificities of hsp70 molecular chaperones. Methanol fixation of Gram-stained smears was compared to heat fixation.

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SCI individuals were predisposed to excessive abdominal obesity, and higher leptin levels were strongly associated with higher prevalence of abdominal obesity in this population. A 61-year-old man with chronic hepatitis B and dyslipidemia visited the emergency department with a fever and severe headache. Use of a nanoparticulate carboxymethyl cellulose film containing sinigrin as an antimicrobial precursor to kill Escherichia coli O157:H7 on fresh beef. Pulmonary hemorrhage after coronary stent placement was commonly misdiagnosed and was associated with significant morbidity and mortality in our patients.

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Regular prednisone use is associated with decreased cognitive functioning in middle-aged patients with SLE. The authors consider local anesthesia to be the method of choice in diagnostic fibrobronchoscopy. Salivary and tear fluid are required for the proper function of the epithelial layer from which they are secreted. All examinations were performed by the authors, who had no any clinical information of the patients, to differentiate between benign and malignant adnexal masses using IOTA simple rules.

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This approach is accomplished through a middle fossa craniotomy and involves removal of the bone anterior and medial to the internal auditory canal and medial to the cochlea and carotid artery. Human PL was moderately active in the turtle kidney assay, weakly active in the Ambystoma radioreceptor assay, and inactive in the bullfrog assay.

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At least for the Simon effect, the results can be interpreted as evidence that relative spatial coding is functionally related to the position of the focus of attention. However, due to limitations related with number and size of the included studies, more RCTs with high quality are desirable for making recommendations with more certainty. While emergency nurses do report violence, they do not use the formal reporting system. The primitive function of GnRH-like molecules in craniates may have thus been both neuromodulatory and hypophysiotropic. Some genes were commonly identified as candidate reference genes in more than two tissue, while others were tissue-specific.

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2) Concentration in tissues: Clindamycin-2-phosphate activity was demonstrable at the concentrations of 1.6 approximately 2.3 mug/g in human palatine and mucous membrane of maxillary specimen one hour after the intramuscular injection of 300 mg. A calcium shift (1.1 mM CaCl2, 10 microM linoleic acid) for 8 days triggered an increase in mRNA levels of keratin 10 (75-fold), profilaggrin (55-fold), glucosylceramide synthase (40-fold), beta-glucocerebrosidase (30-fold), prosaposin (15-fold), acid sphingomyelinase (5-fold), and serine palmitoyltransferase (SPTLC2, 4-fold). Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome. One underwent a pars plana vitrectomy for removal of the vascularized vitreous mass that obscured the retina.

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Within this region we found a potential cAMP-response element (CRE) besides several other putative binding sites for transcription factors. The initial processes of the new wall formation over the grafts were similar to those observed in the organization of thrombis. The results of reconstitution of humidity profiles up to 17-km altitudes are given based on results of laser sounding.

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The patient exhibited a poor response to immunosuppressive treatment and a slow resolution of the thrombocytopenia. This organism is widespread in the environment and may need to be considered in undiagnosed chronic infection in the immunologically suspectible host, as it poses unusual problems in diagnosis and therapy.

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Here we report that thrombin responses in platelets from PAR3-deficient mice were markedly delayed and diminished but not absent. The molecular mechanism of this co-translational insertion process is unknown. Rabbit anti-serum to the beta-form of the preparation of Pesticin has been obtained.

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In this chapter, we review examples and methods for profiling small molecules on high-content functional protein arrays and discuss considerations for troubleshooting. Stability of respiratory syncytial virus in a new bentonite holding medium. Poliovirus variants selected on mutant receptor-expressing cells identify capsid residues that expand receptor recognition. Regular laboratory controls revealed in some cases toxic organic reactions. However, PD-1/PD-L1 blockade-treated mice eventually succumb to disease due to selection of PD-L1 mAb-resistant tumor cells.

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The rarity of this disease explains the lack of a standard management. Effects of specific D-1 and D-2 dopamine agonists (LY141865 and SKF-38393) and pergolide on urinary output of rats. On the other hand, pallidal responses to electrical stimulation of the striatum display a topological antagonistic center-surround organization, probably resulting from lateral inhibition. melitensis Rev 1 is S and thus interferes in serological testing for S brucellae, wadB mutant represents a candidate vaccine to be evaluated against B. At variance, control peptides similarly conjugated had no effect on NK activity.

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The fate of neonatally injected effector cells of allergic encephalomyelitis. Repair of a mandibular defect with a free vascularized coccygeal vertebra transfer in a dog. A theoretical approach was used to find conditions minimizing the electrohydrodynamic effect, mainly responsible for protein dispersion, for the separation of bovine serum albumin and alpha-lactalbumin from bovine milk. Ambulatory treatment of disorders of heart rhythm and conduction

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As a control group, we used a sample from the Birth Registry matching every case by year of birth, autonomous region of residence and sex with six controls. The recirculating pool of mature T cells is formed during young life through gradual release of naive T cells from the thymus.

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A 65-year-old female patient was referred to our hospital for cervical spine surgery under general anesthesia. Like other solid tumors ovarian tumors have been intensely investigated these past years to isolate specific tumoral antigens. The distribution of deficient Pi types over the area was remarkably uneven, Pi type Z being more predominant north and Pi type S south of the Rhine. In this paper we present the characteristic pattern of mood changes in women with and without menstrually-related mood syndrome. Letter: Need for psycho-intellectual rehabilitation of the elderly

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With the improved requirement of postoperative quality of life in patients, intentional incomplete resection should be considered as an acceptable treatment option. When the intravenous dose of chelator was increased incrementally to as high as 16,000 mg per 24 hours, iron excretion increased up to 180 mg per day. miRNAs affect the development of hepatocellular carcinoma via dysregulation of their biogenesis and expression. Selective aggregation of PAMAM dendrimer nanocarriers and PAMAM/ZnPc nanodrugs on human atheromatous carotid tissues: a photodynamic therapy for atherosclerosis.

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TNDM and TIH are different clinical and genetic entities with specific pathophysiological mechanisms. Macrophage activation with lipopolysaccharide had no effect on expression of SERT mRNA or protein. Spontaneous resistant mutants were initially isolated from each strain at frequencies of 10(-4) to 10(-5). A single 3.6-mg Zoladex subcutaneous depot injection was effective in suppressing the pituitary-ovarian function for about 5 weeks in nine regularly menstruating, premenopausal volunteers.

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Lastly, we focus on the current and developing tissue-engineering approaches for the preparation of such 3D constructs: top-down, bottom-up and integrative. Coincidentally, lymphoid cells from these mice generate sufficient endogenous T helper activity to activate the tolerogen-specific cytotoxic T cells. Moloney murine leukemia virus induces myeloid leukemia when inoculated intravenously into pristane-primed adult BALB/c mice. To date, no protein domain has been identified that binds specifically to Ptdlns(3)P and thereby recruits/activates downstream effectors of Ptdlns(3)P signaling.

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Novel inhibition of carbonic anhydrase isozymes I, II and III by carbamoyl phosphate. Bacteria were recovered after aerobic culture of cervical swabs on more occasions 48 h after than before uterine biopsy, but they were considered not to be significant. Clinico-genetic analysis of anencephaly and spinal cord hernia and their prevention Recent advances in transgenic technology, representational difference analysis, and other molecular methods now make feasible the positional cloning of QTLs that influence sensitivity to drugs of abuse.

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As controls, histologically normal breast tissues from 10 patients with no breast tumor were included. It is also clear that diffusible angiogenic stimuli can be released not only from most solid tumors, but also from at least three non-neoplastic cells. Out of a total of 10,530 patients, 1,408 had biopsies which were classified as either bland fibrocystic or hyperplastic. Erythema multiforme is a rare skin condition, easily diagnosed based on its characteristic clinical appearance, but remains a challenge for the physician in terms of establishing its causal agent. Unexpected complications occurred in the form of a reversible ischemic colitis in two patients and an arterioenteric fistula in a third.

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Morbidly obese patients undergoing laparoscopic bariatric surgery are at risk for intraoperative complications relating to the use of CO2 pneumoperitoneum. Endoscopic ultrasound (EUS) is gaining traction as an alternative method of biopsy. The ultrastructure of the visceral yolk sac endoderm of in vivo developing 9- to 13-day-old embryos from 2 diabetic rat models (streptozotocin diabetes and Cohen--genetically determined--diabetes) and from nondiabetic rats fed high sucrose diets have been studied. However, unlike what might be expected of a developmental inducer, our data demonstrate that glucocorticoids act as reversible regulators of glutamine synthetase transcription. This heterogeneity of the expression patterns of Bcl-2 genes could explain the different susceptibility to undergo apoptosis, the different threshold to ischemic damage and the different adaptive capacity to injury among these tubular segments.

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Although treating them as formed by isolated ions with no charge transfer between them, the invariom approach provides features of interionic contacts that are amazingly similar to those obtained from conventional charge density analysis of high-resolution X-ray diffraction data, thus emerging as an easy way towards reliable description of chemical bonding peculiarities in ionic crystals. The influence of isosorbide dinitrate on hemodynamics and gas exchange was studied in 10 patients with coronary artery disease and 10 patients with chronic cor pulmonale. This finding suggests that training with low-intensity sound can increase the sensitivity of cortical neurons. Immunologic responsiveness of patients with cancer: relationship to tumor type, stage and prognosis. Such B cells can be induced by inoculation of a protein-Ars conjugate in CFA.

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Variations in human aortic fatty streaks among geographic locations. This genome consists of 10 double-stranded (ds)RNA segments of different sizes, three large, designated L1-L3, three medium, M4-M6, and four small, S7-S10.

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To evaluate the role of eosinophilic infiltrates in these diseases and to detect the presence and activity of eosinophils, we compared the serum levels of eosinophil cationic protein (ECP), an eosinophil-derived protein, in 11 healthy subjects and in 10 patients with pemphigoid diseases (8 with bullous pemphigoid, one with cicatricial pemphigoid, and one with herpes gestationis). The kinetics of DNA alkylation, repair and replication in hepatocytes, Kupffer cells, and sinusoidal endothelial cells in rat liver during continuous exposure to 1,2-dimethylhydrazine. Further investigation of pain relief, using validated pain assessment scales, as an outcome in VOE management is warranted. Eight patients with non-celiac atrophy and 15 with lymphocytic enteritis secondary to Helicobacter pylori acted as control group.

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A case of a human tail associated with lipomyelomeningocele is reported. The pattern of arrhythmias following capacitor discharges of increasing amplitude, which have been observed by the authors in cultured myocardial cells from chick embryos, was compared to the arrhythmia patterns caused by similar discharges in experimental animals and humans, as reported in the literature.

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The secondary endpoint was the assessment of CAD risk factors like low exercise capacity and obesity, in both groups of patients. Compared to the solvent-treated females, females treated with R1881, TP or EB spent more time near sexually active males. Whereas in vitro maturation is technically more demanding than conventional in vitro fertilization for the laboratory, it carries many potential advantages, for example, in terms of lower treatment heaviness and removal of risk of severe ovarian hyperstimulation syndrome for the patients. Requirement for BUB1B/BUBR1 in tumor progression of lung adenocarcinoma. Experimental studies have suggested that exogenous carnitine administration during these events has a beneficial effect on function.

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A case of aneurysmal bone cyst of the thoracic spine treated with serial particulate embolization responded with involution of soft-tissue and cystic components and diffuse ossification of the mass. Rupture of leiomyosarcoma uteri with hemoperitoneum clinically simulating ruptured ectopic pregnancy. Increasing concentrations of 5-hydroxytryptamine (5-HT) from 10-10 to 10-5 mol/L were applied to induce gradual increase in force of contractions of circular artery segments. Using single-strand conformational polymorphism analysis and direct sequencing, a mutation within exon 3 of the gene encoding proteolipid protein (Gly73Arg substitution) was previously detected in both brothers and their mother, establishing the diagnosis of Pelizaeus-Merzbacher disease. The clinical syndromes and the serological features of MCTD are described.

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Retained cartilage in the ulnar metaphysis with deformation of the forelegs in two litters of captive wolves. Myelography may be not only of diagnostic value but also therapeutic in SIH.

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Exposure risks to children may be reduced by using radiography only when there is a specific clinical indication. The emergence of glycopeptide-resistant Enterococcus faecium (GREF) in a Greek intensive care unit was studied by amplified fragment length polymorphism analysis and esp gene detection. Haemodynamic studies with impromidine in anaesthetised cats and rats. An improved understanding of the pathogenesis of HCC development would facilitate the development of more effective outcomes for the diagnosis and treatment of HCC at earlier stages.

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Surgery of thyrotoxicosis associated with diseases of the central nervous system This knowledge might be important while selecting therapy for patients with hemorrhoids.

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Because arbitrarily selected discount rates for future health effects can radically change the cost-effect ratio, the determinants of the ratio--differences in the present values of effects and costs-are examined for a wide range of discount rates. Pulmonary artery sling was successfully treated by division and reimplantation of the left pulmonary artery in identical twins.

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The number of osteons/mm2 and of osteon fragments/mm2 was greater in specimens from older men but the average area/osteon and area/osteon fragment was greater in specimens from younger men. The investigations were repeated in the patients after 12 weeks.

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Fifteen patients with stage II-III multiple myeloma were intended to undergo two sequential cycles of myeloablative chemoradiotherapy with autologous bone marrow or blood stem cell transplantation after response to primary induction chemotherapy. Teashirt binds to, and requires, Armadillo for the naked cell-fate choice in the larval trunk. Inhibition of substance P-induced biting and scratching by intrathecally administered antinociceptive agents is likely mediated by post-synaptic receptors. The literature is reviewed and the effects of irradiation on bone growth, and possible malignant change, are discussed. The impact of human immunodeficiency virus on mortality of patients treated for tuberculosis in a cohort study in Zambia.