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Effect of N-(6-aminohexyl)-5-chloronaphthalene-1-sulfamide (W-7) and its analogs on the activity of soluble guanylate cyclase and on human platelet aggregation What is echoplanar imaging, and could you please explain its merits and clinical implications? The alkylation interference assay, which identifies essential phosphate sites, was used to define the extent of perturbation on the protein-DNA complex by the modified nucleotide.

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An association of rs2312147 in the VRK2 gene with schizophrenia was also previously reported in the Chinese population, so this marker may be considered as possibly race-specific. S-LAM in men: is pulmonary function different from that seen in women? The annotation framework incorporates annotation by data source integration, data analysis, and manual data entry. They all share a triple-helical segment of variable length (100-450 nm) but differ considerably in the size and nature of their globular domains. Thus, BAK likely functions with other members of the BCL-2 family in the regulation of apoptosis in the human uterus.

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The dipyridamole test in the diagnosis of coronary insufficiency (comparisons with the isoproterenol test and the cycloergometric exercise test) Cellular regulation of i and I antigen expressions in human erythroblasts grown in vitro. They discuss the etiopathogenic factors, and do not consider their case as a new mucopolysaccharidosis, but rather as a generalized disease of the collagen of bones. The plant SMO amino acid sequences possess all the three histidine-rich motifs (HX3H, HX2HH and HX2HH), characteristic of the small family of membrane-bound non-haem iron oxygenases that are involved in lipid oxidation. This stabilization was not detectable by conventional sucrose gradient centrifugation because of artifactual dissociation of untransformed complexes, a pitfall overcome by resorting to vertical tube centrifugation.

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Dengue viruses were cultivated in Balb 3T12-3 cells, a continuous line of cells derived from mouse embryo cell cultures. The toxicity of the compounds was assessed by determination of their approximate LD50 on albino mice.

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ACE-I-renography has a high positive and negative predictive value in diagnosing renal artery stenosis. In one case, it was after 9 months after the operation, we had to extract one implant due to extruzion of the tube. Chronic inhalational exposure of sensitized mice to low-mass concentrations of OVA induces airway-specific hyperresponsiveness. Venous thrombosis and splenic rupture in paroxysmal nocturnal hemoglobinuria. Mitogenicity, estimated by the incorporation of tritiated thymidine is maximal on the 5th and 6th day of culture, for high cellular concentrations and for 10 micrograms/PI/well.

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Mammograms were obtained at baseline and after 9 cycles (each 28 days) of treatment. The existence of such a coselection in genetically selected models provides an advantageous tool for the study of genetic influence on emotional reactivity and the mechanism of linkage between behavioral and neuroendocrine traits.

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The R VennDiagram package was applied to identify the overlapping miRNAs with differential expression among these three studies. Both experimental and observational work revealed that increasing diversity reduced the performance of alien but not native invaders. Antibody-negative acquired myasthenia gravis: successful therapy with plasma exchange.

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We found no association between PON2 variation and plasma glucose or insulin. Of the 11 long-term survivors, nine patients rated their health as good to excellent (eight rated it the same or better than before surgery), eight had no or minimal physical disability, and 10 remained as involved socially as previously. Pulmonary function analyses were conducted for each group at the 3-, 6-, and 12-mo sacrifices. Human subcutaneous tissue distribution of fluconazole: comparison of microdialysis and suction blister techniques. Austrian nutrition and lifestyle recommendations for gout and hyperuricemia

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Anti-p53 antibodies have been found in sera of patients with several types of cancers including breast cancer. Compared to littermate control animals the postnatally undernourished rats were more susceptible to the kindling treatment. While computed tomography (CT) and digital subtraction angiography (DSA) have been the methods of choice in the diagnostic management of this symptom and its related diseases, the technical progress in the development of MRI and MRA highly recommends these techniques as additional yet sufficient imaging tools. Small differences in the relative contributions that are assigned to important residues for explaining binding affinity differences can be directly linked to structural differences in the modelled enzyme-substrate complexes: (i) rotation of all substrates in the active site about their longitudinal axis, (ii) repositioning of the ring of epihalohydrines and the halogen substituents of 1,2-dihalopropanes, and (iii) altered conformation of the long-chain molecules (halobutanes and halohexanes).

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Busulfan, carmustine (BCNU) and mitomycin C cause veno-occlusive disease (VOD) of the liver in some patients and the latter two agents also cause interstitial pneumonitis. Experimental study on the effect of hydroxyethyl starch on erythrocyte aggregation and microcirculation These findings do not support the hypothesis of dominant centralizing effect of VMO on the patella in extension, but the effect of the VMO may be more clearly demonstrated by measuring PTA in both QC and QU positions. Effects of a glucoside-hydrolase inhibitor (Bay g 5421) on serum lipids, lipoproteins and bile acids, fecal fat and bacterial flora, and intestinal gas production in hyperlipidemic patients.

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Members of a series of monoclonal antibodies directed against antigenic determinants on either the amino or the carboxy terminus of the T-ag polypeptide were able to precipitate surface T-ag (as well as nuclear T-ag) from both SV40-transformed and SV40-infected cells. coli infection by interfering with adherence processes (anti-intimin and anti-bundle-forming pili antibodies) and cell signaling (anti-enteropathogenic Escherichia coli-secreted protein A and B antibodies. Daily temperature extremes play an important role in predicting thermal effects.

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In contrast to Ca, Mg did not alter the time course of relaxation. On two additional eyes, full-thickness argon laser iridectomy was unsuccessful. Tissue distribution of the mouse Cyp2j isoforms confirmed similar patterns of expression between the two qPCR methods. This study included 281 Japanese patients with hypercholesterolemia, and 267 control subjects. typhimurium mutants that were stable carriers of Rms312 were isolated by alternate culture of R-bearing cells in a medium containing either tetracycline or chloramphenicol.

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Biopsies of the epididymis and scalene nodes established the diagnosis. Therefore, in this study we investigated the influence of repetitive HBOT on the reactive astrogliosis and expression of mediators of inflammation after cortical stab injury (CSI). At test, they were presented with old words in the same pairing as at study (same pairs), old words in a different pairing from study (rearranged pairs), and pairs of new words. The comparison of standard radial band-limited and separable Haar reconstructions shows that improvements, in terms of linearity, shift-invariance and aliasing, can be obtained even for the case of a limited number of views. Real evaluation of any vaccine can only be done after the vaccine has been in routine use for a substantially long period of time.

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Additional seizure recurrence occurring after AED taper, poor drug compliance and even while patients continue on AEDs after surgery leave only approximately one-third of patients cured after temporal lobe resection. Diagnosis of ruptured abdominal aortic aneurysm: a multicentre cohort study. Multispectral image compression algorithms for color reproduction Interleukin 6 gene transcripts are expressed in human atherosclerotic lesions.

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Neutropenia in patients with rheumatoid arthritis, treated with sulphasalazine. The results showed that in all treatments, the daily average number of eggs per female ladybird was about 40-55. The relationship of erythropoietin and iron metabolism to red blood cell production in humans.

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The different signals that converge on mitochondria to trigger or inhibit these events and their downstream effects delineate several major pathways in physiological cell death. Ultrastructural, cell membrane, and cytogenetic characteristics of B-cell leukemia, a murine model of chronic lymphocytic leukemia.

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We use the notion of emergence to consider the sorts of knowledge that can be produced in a collaborative research project. Ascending olfactory information and centrifugal influxes contributing to a nutritional modulation of the rat mitral cell responses. Pegylated interferon-alpha 2a treatment of chronic SIV-infected macaques.

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Entamoeba mitosomes play an important role in encystation by association with cholesteryl sulfate synthesis. An electron spin resonance study indicated that these compounds possess anti-radical activity.

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A simultaneous evaluation method of purity and apparent stability constant of Ca-chelating agents and selectivity coefficient of Ca-selective electrodes. An individual with Hb-Lepore-Baltimore- delta beta-thalassaemia in a Yugoslavian family. In vitro exposure to fresh and dialyzed saliva and various undersaturated solutions indicated that the intraoral decrease was due to mineralization rather than to pellicle formation. Syncope in patients with chronic Chagasic heart disease (CCHD) is a frequent but poorly studied problem. Some haematological and physical characteristics of a group of Papua New Guinea highlanders.

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The musculocutaneous nerve and its motor branches to the biceps and brachialis were dissected and studied under the operating microscope in 24 fresh-frozen cadaveric specimens. Convergence is observed, but differs depending on the dialect of the speaker, the dialect of the model, the particular word class being shadowed, and the order in which dialects are presented to participants. Due to the minimum free energy model, it is very important to predict the RNA secondary structure accurately and efficiently from the suboptimal foldings. Hormone measurements were made for 5 consecutive days before and daily during a 7-day treatment period with PTU, 1,000 mg/day.

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Transepithelial signaling to neutrophils by salmonellae: a novel virulence mechanism for gastroenteritis. This disease primarily affects children and is caused by the presence in the digestive tract of a common roundworm of dogs, Toxocara canis, or cats, Toxocara cati. The uaYc462 allele was mapped physically in relation to known loss-of-function alleles and sequenced.

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Propagation of two orthogonally polarized time-delayed optical solitons in low-birefringence optical fiber is studied experimentally. All of the major receptive field types were affected in a similar fashion, irrespective of their position in the visual field. Effect of alcohol on the lipid makeup of various sections of the human myocardium and blood plasma Except for anticytochrome P450 2B1 and polyspecific antibody to the cytochrome P450 2C subfamily, the antibodies listed above did not cross-react with polar bear lung microsomes at the protein concentrations used.

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Using Expressed Sequence Tags (ESTs) deposited in the data banks, a cDNA has been assembled that encodes a protein related to the hyaluronidases from bee venom and mammalian sperm. However, at higher elevations the lack of net basal area change and excess of mortality over recruitment suggests negative environmental impacts.

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After operation, 3 x 10(6) unit per day of IFN-alpha were administered three times per week. First, we examined the effectiveness of the hybrid peptides for cell attachment and proliferation using normal human dermal fibroblasts (NHDF) in vitro. The blood volume monitor is based on the principle that the total protein concentration, the sum of haemoglobin and plasma proteins in the vascular space, changes during ultrafiltration.

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Organising a regional teaching programme for the MRCP (UK) examination. Lipids, inflammation and CVD--understanding the basics to break the atherosclerosis cycle. A full-length cDNA clone of barley yellow dwarf virus (BYDV-PAV serotype) has been constructed and fused to the bacteriophage T7 RNA polymerase promoter. To evaluate the renal and hepatic function, through biochemical analysis after 14 days of creatine supplementation in physically inactive rats.

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The findings were interpreted as indicating that some nonverbal retarded children will benefit from sign language than speech training. Until now, the importance of myocarditis as an aetiological factor in the pathogenesis of isiopathic cardiomyopathy has been unknown. The aim of this study was to determine its distribution and possible function in segmental renal infarction.

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Causal link between nucleotide pyrophosphohydrolase overactivity and increased intracellular inorganic pyrophosphate generation demonstrated by transfection of cultured fibroblasts and osteoblasts with plasma cell membrane glycoprotein-1. Modifying a childbirth education curriculum for two specific populations. The present technique supports the clinician with additional fast and noninvasive diagnostic procedure that can facilitate the evaluation of anterior knee instability. Mortality update of workers exposed to acrylonitrile in The Netherlands.

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For example, the restriction enzyme Csp68KII functions optimally at 50 degreesC and Csp68KIII requires higher salt for its activity. Some differences in the organization of liaison psychiatry between the United States and the United Kingdom are discussed. We conclude that oscillations of alveolar CO2 are transmitted to the brain by the circulation and result in oscillations of ECF pH. Nutritional consequences of reoperative surgery in recurrent malignancy. Ethanol stimulated gluconeogenesis from pyruvate and inhibited it from lactate.

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Experiments in the reproducibility of lateral tooth guidance in the Gnathomat Optimization of the physiochemical parameters for the culture of Bombyx mori insect cells used in recombinant protein production. We compared patients having completed the treatment in hospital (H), and those deemed sufficiently stable, and with adequate home environment, for OPAT. After the 2nd day following tumor injection, no blast transformation is noted.

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A significant increase of the haptoglobin type 2-2 (p less than 0.05) was found among SLE patients. An identical abnormal pattern was detected by means of (99m)Tc-hexamethyl-propyleneamine-oxime single-photon emission computed tomography in two siblings with infantile neuroaxonal dystrophy. Nine thousand five hundred twelve prenatal ultrasound studies performed on 4900 patients were reviewed retrospectively for the findings of a failure to visualize kidneys.

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A rabbit antiserum raised against the fusion protein recognized an approximately 45 kD protein in immunoblots of extracts of PSbMV-infected pea leaves that was not present in extracts of healthy leaves. Clinical Oral Findings in Patients With End-stage Renal Disease Receiving Hemodialysis.

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To assess the impact of gender and ethnicity on symptom-to-door time (STDT) in patients presenting with STEMI. This unit can be employed in big biochemical laboratories and in prophylactic institutions. These studies demonstrate that pim belongs to the small group of protooncogenes that can be induced during the primary response to growth factors (fos, myc, and myb) and that constitutive expression of myb, at least at the RNA level, is not sufficient to abrogate the growth factor requirement of hematopoietic cell lines. Nonetheless, the dPFC lesion did not substantially affect the working memory component of the task.

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The histopathological aspect suggested an adenocarcinomatous metastasis with papillary pattern, moderately differentiated. We also learned that Vasa interacted with mRNAs in the perinuclear area and at the spindle in an Importin-dependent manner during cell cycle progression. Placement of a cosmetic prosthesis improved the external appearances in the first 2 cases.

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The treatment of paroxysmal supraventricular tachycardia (PSVT) in pregnancy is not unlike treatment for the general population. Bile induction of 7 alpha- and 7 beta-hydroxysteroid dehydrogenases in Clostridium absonum. Antimicrobial, antitumor and brine shrimp lethality assay of Ranunculus arvensis L.

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Reproducibility of instruments designed to measure subjective evaluation of female stress urinary incontinence. The main results showed that a global fatigue score two months postmyocardial infarction was associated with concurrent symptoms, such as breathlessness and stress, and coping strategies such as change in values, intrusion and isolation. Developmental studies with etiolated and light-treated seedlings suggested that although light had variable effects on the levels of d4h transcripts, those of D4H protein and enzyme activity could be increased, depending on seedling development, up to 9- and 8-fold, respectively, compared with etiolated seedlings. With the use of the estimated cost of a VAP of dollars 4,947 from the literature, the reduction resulted in cost savings of dollars 178,092 and dollars 148,410 in the medical and surgical ICUs, respectively, for a total of dollars 326,482. Prepubertal testicular tumours: Should testicular-sparing surgery be considered?