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We investigated the mechanism of gastroesophageal reflux (GER) in 10 health volunteer subjects. TF expression, persistent 1 month after balloon angioplasty in rabbit femoral arteries and porcine coronary arteries, is attenuated by specific thrombin inhibition with hirudin.

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In this paper a nonlinear inversion method is presented for determining the mass density of an elastic inclusion from the knowledge of how the inclusion scatters known incident elastic waves. Aqueous insolubility of the vanilloids such as capsaicin is a major disincentive in their intravesical therapy of detrusor hyperreflexia. Some retroviral vectors have several more specialized applications in genetics and possibly in medicine. Evidence for cytotoxic functions in well-defined human T cell clones.

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From our data it can be concluded that: (1) A monosynaptic projection from the nucleus reticularis tegmenti pontis to the VN can be excluded. Adaptation to diet of mRNA coding for pancreatic amylase and serine proteases in the rat Brown adipose tissue: the dominant site of nonshivering thermogenesis in the rat. Thus, amino acid residues that define a peptide motif represent side chains required or preferred for a close fit with the MHC class I heavy chain. Vestibulometry and its importance in elucidating the pathogenesis and prognosis of the course of nervous system diseases in children

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The HBV-transfected cells are especially useful in defining possible in vivo differences in responses to cytokines with respect to HBV production, apoptosis and clonal cell growth. Cytotoxic activity of peripheral blood and cerebrospinal fluid lymphocytes from patients with multiple sclerosis and other neurological diseases: analysis at the single cell level of the relationship of cytotoxic effectors and interferon-producing cells. A single base mutation in an I-A alpha-chain gene alters T-cell recognition. Some effects of acoustic attributes of speech on the processing of phonetic feature information. IFN-alpha is produced in the leukocytes infected with virus, while IFN-beta is from fibroblasts infected with virus.

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On the other hand, deamination of C in the CpG central dinucleotide (CpG----UpG) causes an increase of binding affinity which is further enhanced by the contemporary deamination in both strands. These and other findings provide strong evidence that the relationship between physical and perceived space is noneuclidean, and that the three-dimensional structures of objects can appear systematically distorted even when viewed under full cue conditions. However, sharedness does not mean identicality, otherwise representations of self and others would completely overlap, and lead to confusion. ARH-77 cells do not adhere to type I collagen and readily invade into collagen gels, but following expression of the transmembrane heparan sulfate proteoglycan syndecan-1, they bind collagen and fail to invade. The clinical and pathological signs were sufficiently similar to those reported during the 1982-1986 outbreak to establish a positive diagnosis.

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In the present study, we attempted to manipulate anti-DNA antibody production through the antigen-cytotoxic drug conjugates, DNA-daunorubicin complexes. Elevated plasma aluminum levels in normal infants receiving antacids containing aluminum. In order to follow the ICF model, interpretation of mRS rating requires caution. Antigen presentation by human dermal microvascular endothelial cells.

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One hundred sixty patients with hepatocellular carcinoma underwent an ultrasound-guided fine-needle biopsy, providing material for cytological and histological study. The pumice stone is very helpful in removing hyperkeratotic tissue and can be used alone or following treatment of the skin with a keratolytic agent.

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However, these preliminary estimates might change when further research is able to make into account a number of additional factors affecting the relationship between mortality and climate. Idiotypic cross-reaction between MRL monoclonal autoantibodies with different antigen specificity. Since the spectrin-actin lattice, which has been suggested to play an important role in stabilizing membrane phospholipid asymmetry, is abnormal in sickled erythrocytes, we determined the effects of sickling on membrane phospholipid organization.

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The differences in molecular weight, carbohydrate content, thermal and pH-stability and sensitivity towards SH-group reagents are found. indica leaf extracts using bioactivity guided manner for identification of the active anti-inflammatory principles. Cellular shape changed from predominantly stellate in the luminal regions of the elastic-hyperplastic layer to elongated spindlelike cells in the musculoelastic layer of the intima.

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The pUL38-independent mode of mTORC1 activation also has been reported. The benefit of intrafallopian transfer techniques is still disputable in assisted reproductive techniques. An increased level of all-trans-beta-carotene in the system led to a decrease in the percentage of beta-carotene incorporated into the micelles. Measurements were obtained at baseline, 1 week after the cessation of treatment, and 12 weeks after the cessation of treatment. Histologically the lesions show transepidermal elimination of altered dermal components into a cup-shaped epidermal depression.

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In the case of the Orange II staining a serious reduction in dye binding capacity was found in both situations. Regulation of glycine-insensitive desensitization of the NMDA receptor in outside-out patches. Only two cases of GIP induced by nitrofurantoin have been reported in the medical literature. It was found that cystamine reduced the serum imipramine level to control values but had no effect decreasing the level of desmethylimipramine.

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In patients with atrioventricular (A-V) nodal re-entrant paroxysmal supraventricular tachycardia (PSVT), atrial extrastimulus technique frequently reveals discontinuous A1-A2, H1-H2 curves suggestive of dual A-V nodal pathways. Regional variation in the expression of pemphigus foliaceus, pemphigus erythematosus, and pemphigus vulgaris antigens in human skin. The amphicrine pancreatic cell line, AR42J, secretes GABA and amylase by separate regulated pathways.

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Theoretical accommodation calculated from the forward shift of the lens optics (decrease of ACD) using paraxial geometrical optics and measured accommodation amplitude. We have investigated the viscosity of different commercially available polymers in solution and found that dextran has a low viscosity compared to other polymers of comparable molecular weight and resolving power.

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Also, a comparative study using 10 real-case urine specimens previously screened as positive for MA administration showed mostly tolerable biases between the two sums (of concentration) of D- and L-MA obtained via an asymmetric L-TPC-ChD approach and via an ordinary pentafluoropropionylation (PFPA-ChD) approach, respectively, as well as between the two sums of D- and L-AP obtained thereupon, thus validating the proposed analytical scheme as a promising forensic protocol for the detailed analysis of enantiomeric amphetamines in urine. Eight monkeys were used in our study to test the material in the periapical and marginal periodontal regions. Few statistically significant differences in eating behavior were observed between obese and normal-weight subjects.

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Topographical analysis of the plasma membrane-associated sucrose binding protein from soybean. Gas chromatographic differentiation of 4-desmethyl-, 4-monomethyl- and 4,4-dimethyl-sterols. To establish a method for identification of the poly(ADP-ribose) binding proteins induced by benzo (a) pyrene.

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An assemblage of mixed wetland and dryland palynofloral taxa is interpolated between a dryland assemblage and an overlying histosol containing wetland taxa. Humans and mice with germline, heterozygous loss-of-function mutations in the MEN1 gene almost always develop at least one endocrine tumor by late adulthood, and examination of those tumors invariably reveals loss of the wild-type allele. Homozygosity for frameshift mutations in XYLT2 result in a spondylo-ocular syndrome with bone fragility, cataracts, and hearing defects. HCK is located on human chromosome 20 at bands q11-12, a region that is affected by interstitial deletions in some acute myeloid leukemias and myeloproliferative disorders. Treatment of acute lymphoblastic leukemia in relapse: efficacy of a four-drug reinduction regimen.

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Prognostic value of ambulatory electrocardiography monitoring in patients with dilated cardiomyopathy. Hypnosis in the management of intractable pain is a valuable but frequently overlooked tool for the practicing physician. Alice Welford (1887-1918), a nurse in World War I: The impact of kindness and compassion. Insensible perspiration from the skin under standardized environmental conditions. Capillary rarefaction and abnormal cardiovascular reactivity in hypertension.

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The comparisons indicate that multichannel noiselet measurement matrix has better RIP than that of its Fourier counterpart, and that noiselet encoded MCS-MRI outperforms Fourier encoded MCS-MRI in preserving image resolution and can achieve higher acceleration factors. These neurons were labelled by retrograde lateral diffusion of DiI after crystals were placed in various locations in the embryonic thoracic cord. Postoperative chylothorax following repair of coarctation of the aorta.

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Two-exponent Lavalette function: a generalization for the case of adherents to a religious movement. Immunological heterogeneity of human monocyte subsets prepared by counterflow centrifugation elutriation. These results indicate the presence of certain component in blood plasma of examined patients which alters insulin binding to receptors.

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The 2-desamino and 2-desamino-2-methyl analogues of AMT and MTX inhibited the growth of tumor cells, but were very poor inhibitors of dihydrofolate reductase (DHFR). Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila. The effect of intraoperative heparin administered during total hip arthroplasty on the incidence of proximal deep vein thrombosis assessed by magnetic resonance venography.

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The effect of transient temperatures on the growth of Salmonella typhimurium LT2. The Trendelenburg position appears potentially useful as a clinical tool to screen for the presence of a low CSF pressure syndrome in patients with daily headache. The enzymes bound tightly to their polysaccharide products but these complexes could be readily dissociated by polyacrylamide gel electrophoresis. Data were collected on quality of life and a multidimensional assessment of household economic circumstances (work status, income, asset ownership, household economic hardship, and catastrophic health expenditure). The results showed that the compounds bearing a chain terminated by a free carboxamide group could interact specifically with GC-rich DNA provided that the length and conformation of the side chain were appropriate.

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In relatively homogeneous populations, leg infection rates did not differ, but other leg morbidities were less for the patients who underwent endoscopic vein harvesting. In the other groups at 3 and 6 weeks the normal shape of the cortex was reconstituting. The context of prescription drug use must be accounted for in designing pharmacy services and in studying service quality from the patient perspective. An infrared study exhibited an enhanced membrane perturbation by the complex formation. Brucellosis in patients infected with the human immunodeficiency virus.

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Combining ecological knowledge of critical system interdependencies with a large-scale experiment, we tested for breaks in the ecosystem interaction network to identify threshold potential in real-world ecosystem dynamics. To estimate the incidence of, and profile the spread of, congenital cardiac defects, and to assess the accuracy of the echocardiographic diagnosis as performed by a neonatologist. Evaluation of in vitro properties of di-tri-octahedral smectite on clostridial toxins and growth. One case of oesophageal carcinoma occurred among 5 cases of corrosive stricture exceeding 20 years in duration.

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By differential hybridization, three complementary DNAs designated as S3, S2, and SA were isolated, and the corresponding messenger RNAs (mRNAs) were differentially expressed between the kidneys of spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto (WKY) rats. The monoclonal antibody HMB45 is used to detect an epitope specific for melanocytes, malignant melanomas and melanoma metastases. Clinical utility of a commercial test based on the polymerase chain reaction for detecting Mycobacterium tuberculosis in respiratory specimens.

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The ultrastructural morphological characteristics of tumor-infiltrating lymphocytes (TIL) and their interactions with tumor cells were studied in a model previously described. Usefulness of TSH administration on increased iodine uptake by the thyroid gland in carcinoma In the Atlantic salmon, specific dopaminergic and nonapeptidergic neuronal subdivisions are proposed to play a role for photoperiod control of endocrine activity. Long-term results of aortocoronary bypass graft in patients with multiple arteriosclerotic vascular diseases

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The difference was statistically significant with error probability of 0.05. Intuition is related to heuristic techniques and uses them (representativeness, availability, anchoring).

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Thus, the excessive risk for DR3/4 individuals appears to depend on secondary interactions between DR and the environmental factors that trigger the onset of this disease and does not in itself indicate the existence of distinct susceptibility alleles in coupling with these genes, i.e., of genetic heterogeneity or overdominance. Water consumption was measured in 199 suckling pigs aged 1 to 28 days. A severe form of Salmonella enterocolitis with neurologic involvement can lead to optic nerve lesion with consequential loss of vision. The gestationally and lactationally-exposed female offspring of these rats showed a major increase in the levels of growth hormone at 100 days of age.

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Insights into the Molecular Pathogenesis of Activated B-Cell-like Diffuse Large B-Cell Lymphoma and Its Therapeutic Implications. We tested this hypothesis by creating isogenic strains of gliotoxin-producing and nonproducing strains.

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Despite extensive diagnostic examinations no other cause of the scotoma could be evaluated. The inhibitor ABIN-2 disrupts the interaction of receptor-interacting protein with the kinase subunit IKKgamma to block activation of the transcription factor NF-kappaB and potentiate apoptosis. The aspiration biopsy cytology was performed from skin lesion, the diagnosis was class V.

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In summary, our data emphasize that GBMs show a disturbed hydroxymethylome that is disrupted by IDH1 independent pathways, and that loss of 5hmC shows astonishing intratumoral heterogeneity. These methodologic details have been an important limitation to test application when traditional protocols and measurement procedures are required. To draw attention to the absence of a concept of personal existence in standard psychiatric approaches to mental illness. It has been proposed that positive feedback operates via Cln/Cdc28 activation of the Swi4/Swi6 transcription factor, leading to CLN1 and CLN2 transcription due to Swi4 binding to specific sites (SCBs) in the CLN1 and CLN2 promoters. The main site of origin for malignancies detected during risk-reducing surgery for ovarian cancer.

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Work outcomes of sickness absence related to mental disorders: a systematic literature review. Obstructive sleep apnoea, and possibly snoring, are associated with a poorly understood increase in cardiovascular mortality which may be explained by their effects on systemic blood pressure during sleep.

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Relationship between infectivity and OspC expression in Lyme disease Borrelia. During a median follow up of 7.5 months (range 2 to 21 months) only 4 of the 18 patients had objective tumor progression.

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The importance of the receptor ligand system IL 2-receptor and IL 2 for the regulation of the T-cell proliferation was confirmed recently. Differences in mean amino acid digestibility among feedstuffs, and the variability in the digestibility of an amino acid within a feedstuff should both be taken into account during least-cost dietary formulation.

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Therapeutic approach for patients with scimitar syndrome, respiratory manifestations and onset beyond the neonatal period, should be conservative. However, distal flow status, incorporating collateral capacity, is not well predicted by the severity or location of the disease. This report describes the Case Record Rating Scale, an instrument designed to provide a standardized method for abstracting case record information.

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A follow-up visit was organised after 1 week and after 4-6 weeks with a duplex. First, the patient and family members are serologically typed to define HLA haplotypes and to search for HLA genotypically identical siblings. Pixels in the image are presented by their nearby neighbors, and are modeled as a patch. Triazolam and zolpidem decreased alcohol-heightened and non-heightened aggressive behavior, and these antiaggressive effects were accompanied by reduced motor activity, indicating sedation. The Tetrahymena IFT172 gene encodes a protein with an N-terminal WD domain (WDD) and a C-terminal repeat domain (RPD).

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LDL-like lipoproteins extracted from human aorta had some of properties of oxidized LDL, such as the recognition of materials present in atheroma by antibodies against oxidized LDL and the presence of autoantibodies against oxidized LDL in human sera are in favor of the pathogenetically important role of the oxidation of LDL. Risk factors for relapse in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis: tools for treatment decisions? V23, like TMV and TMGMV, caused systemic infection in Nicotiana tabacum Xanthi.

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A prospective study of the level of disability, severity and distribution of relapses in 15 women with multiple sclerosis prior to, during and up to 3 years following pregnancy was undertaken. There are two strategies to prevent pouchitis, the primary (i.e., the prevention of the initial episode) and secondary (i.e., the prevention of recurrent episodes) prophylaxis. Seriously ill patients as living unspecified kidney donors: rationale and justification. Endoscopic, transmural drainage and necrosectomy for walled-off pancreatic necrosis The aim of this study was to provide an overview of foetal/neonatal alloimmune neutropenia (FNAIN), together with advice on the clinical management.

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We also measured the diffusion coefficient of fluorospheres in glycerol solutions and recovered the values expected according to the Stokes-Einstein relationship for viscosities higher than 3.7 cP. The social adjustment of patients with schizophrenia: implications to the mental health policy in Brazil. Proceedings: Inflammatory disease of the large bowel in children.

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Treatment was surgical excision of both the cervical and CNS lesions achieving complete removal of the lesions and resolution of her symptoms. Birth weights are important in relation to perinatal mortality, which is notoriously high among Asians. Besides its role in viral assembly, the vesicular stomatitis virus (VSV) matrix (M) protein causes cytopathic effects such as cell rounding (D. Observation on the therapeutic effects of sheng wei ning tablets on peptic ulcer--an analysis of 199 cases Selective stimulation by mouse spleen cell conditioned medium of human eosinophil colony formation.

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Removal of sufficient dye-stained tissue is therefore recommended to prevent further carious assault from residual S. The latter has been described in protein with antiprotease activity. AT low doses both these radiations are more effective than hard X-rays in producing dicentric aberrations, but at high doses aluminium X-rays are less effective than hard X-rays because of the large positive curvature of the hard X-ray dose-response. The majority of the mutations affected residues in the transmembrane segments that are predicted to face the helix bundle.

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An electron microscopic study revealed that the parasites were different from those described from sheep in former publications. Using a mutation affecting endocytosis (shibire) we find that patched is a membrane-bound protein, which is internalized by endocytosis, and that the preferential sites of accumulation resemble the described localization of the cell-cell adhesive junctions of the epidermal cells. Patients and their families deserve sound nutrition advice from primary care practitioners. Physical examination revealed more changes in their skin and nails, but no differences in height or weight compared to non-working group.