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Doridosine was shown to cause prolonged reduced arterial pressure and reduced heart rate in the rat. Customarily, heparin is used to prevent embolic complications arising during percutaneous mitral balloon valvuloplasty (PMBV), but this may prolong hospital stay and increases the risk of bleeding, hemopericardium and cardiac tamponade. The latter one presents a higher affinity in the resting state for p47phox.

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The maximum occurred at a surface area where the equilibrium contact angle would suggest that a substantial proportion of the surface area was bridged. In ground-glass hepatocytes expressing viral antigens, an unusual accumulation of CK8/18 was observed, but there was no evidence of preferential necrosis of ground-glass hepatocytes.

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This fundamental difference affects the research methodologies that are appropriate to the field. We found the age to have a marked influence on the value of calcium, magnesium and creatinine, including urinary concentration ratios of calcium/creatinine and magnesium/creatinine. The main objective of the current investigation was to compare the effects of a tablet-based interactive distraction (TBID) tool to oral midazolam on perioperative anxiety. To study chromosome complements of chronic lymphocytic leukemia cells, six Epstein-Barr virus-transformed lymphoid lines were established from two patients with this disease who were heterozygous for the X-chromosome-linked enzyme glucose-6-phosphate dehydrogenase (G6PD).

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Tumor lysis syndrome, characterized by multiple metabolic abnormalities resulting from abrupt tumor cell death and release of intracellular constituents and metabolites, is most commonly associated with the treatment of highly chemotherapy-sensitive lymphoid and leukemic neoplasms. 2D FLASH MRI with 30 degrees flip angle can show the differences in water content in the cartilage and thus permit to detect early chondromalacia lesions in the deep cartilage.

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Properties of a new drug famocid: indications and contraindications of its use? Lysosomal hydrolases as indicators of plaque-induced bone resorption in tissue culture were studied. Here we review three important technological advances in these new methodologies, and discuss their prospects for applications in areas including plasmon-induced chemistry and sensing at very low limits of detection.

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Repeated measures of basal and tryptophan-induced changes in tryptophan and serotonin blood concentrations were characteristic for individual subjects. Pathway analysis of these proteins suggests that Myc proteins function as the regulator of M phase initiation by controlling expression of the Akt1 molecule that ultimately inhibits the Cdc2-cyclin B complex in cells. The X-ray structures of porcine pancreatic kallikrein and of its complex with bovine pancreatic trypsin inhibitor. These cellular genes have the capacity for conversion to oncogenes (c-onc) that are capable of inducing or maintaining the transformed state when they are overly expressed or altered by mutation or rearrangement.

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Death within 48 hours of anaesthesia at the Vancouver General Hospital. Previously identified suppressors of PEV suppressed white variegation of pericentric and fourth chromosome inserts but not telomeric inserts on the second and third chromosomes. We evaluated the association between hyponatremia and clinical parameters of patients with PDRP. Xeroradiographic observations in four patients with chronic renal disease and cutaneous gangrene. The short median survival time does not justify AILD grouping as low grade malignant lymphoma.

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Nuclear progression, spindle assembly, behavior of cortical granules (CGs) and mitochondria, levels of glutathione (GSH), and dynamics of maturation-promoting factor (MPF) activity during oocyte maturation under different conditions. Transcranial Doppler ultrasound following closed head injury: vasospasm or vasoparalysis? Such an indicator would be useful in selection of those node-negative patients with breast carcinoma who are at high risk for having occult metastasis at presentation. Delusional misidentification and subsequent dementia: a clinical and neuropathological study.

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In this study, we describe a monoclonal antibody, designated alpha-p65MAb, that recognizes an epitope which includes the nuclear location signal (NLS) of p65, the DNA binding subunit mainly responsible for the strong gene-inductory potential of NF-kappa B. Various inflammatory cells and mediators produced during chronic inflammation are orchestrated through different molecular signaling pathways and lead to the formation of a microenvironment in favor of tumorigenesis.

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By means of dextran-coated charcoal assay, the capacity of various endometrial cytosol preparation for specific binding of 3H-progesterone was determined. The survey also showed that in the last 30 days before the survey 64 per cent of the respondents had used alcoholic beverages, 31.8 per cent tobacco, 2.1 per cent inhalants, 13.9 per cent cannabis, 5.3 per cent amphetamines and amphetamine-type substances, 0.8 per cent cocaine, 1.2 per cent hallucinogens, 2.1 per cent tranquillizers, 2.1 per cent sedatives, 2.1 per cent opium, 1.3 per cent heroin and 5.1 per cent other opiates. Serum amino acids, central monoamines, and hormones in drug-naive, drug-free, and neuroleptic-treated schizophrenic patients and healthy subjects.

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It is suggested that this is caused by a difference in the ability to reduce the presumed toxic compounds fumarylacetoacetate and maleylacetoacetate, i.e. Although many drug transporters have been identified at the BBB, the available literature demonstrates only the in vivo functional importance of P-glycoprotein (P-gp) in limiting brain penetration of its substrates. Recently, patients with phenotypes intermediate between types A and B NPD also have been identified.

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Single photon emission computed tomography (SEPCT) images obtained during seizures showed considerable hyperperfusion in the left occipital temporal lobes, while there was hypoperfusion in the left temporo-parietal area corresponding to the lesion of the old cerebral infarction. As PVNS and Chediak-Higashi syndrome are both very rare diseases we propose a potential unifying hypothesis for this combination. Such immunizations suffer from difficulties in producing conjugates of reliable composition, and from unwanted anti-carrier immune responses. With this method, composite scaffolds consisting of poly(epsilon-caprolactone) (PCL) fibers and poly(ethylene oxide) (PEO) microparticles were prepared by simultaneously electrospinning and electrospraying.

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Relatively recent recognition of the particular needs of those who are terminally ill has directed attention to the most humane approaches to the provision of care. Tubulin isolated from either neonate human or rat brain consists predominantly of the more basic alpha and beta isotubulins found in adult brain. The number of polypeptide chains in the rod domain of bovine epidermal keratin. Chronic cerebrospinal venous insufficiency: pitfalls and perils of sonographic assessment. Here we show that the native yeast SAS complex is a small trimeric protein complex composed solely of Sas2, Sas4, and Sas5 with a molecular mass of about 125 kDa.

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These studies should be carried out in the parent generation (F0), directly exposed to chemical agents. Neuronal differentiation is a complex process involving the sequential expression of several factors.

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Ultrasonography is an effective and accurate diagnostic test for acalculous cholecystitis. Also intravesical instillation of pirarubicin was done after the operation. Generally speaking, the most rapid methods were found to be less sensitive and less reproducible than more time-consuming ones. Direct resolution of the stereoisomers of leucovorin and 5-methyltetrahydrofolate using a bovine serum albumin high-performance liquid chromatographic chiral stationary phase coupled to an achiral phenyl column.

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The results suggest that the increased desire to binge in response to stressors reported by subjects higher in disordered eating cannot be accounted for by differences in cardiovascular reactivity or negative hedonic state, relative to what subjects low in disordered eating showed in response to the same stressors. Advantages of plasma thiamin pyrophosphate in the assessment of thiamin status of patients are discussed.

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Concentration-time profile of phenytoin after admixture with small volumes of intravenous fluids. The transition from relapsing-remitting MS to irreversible disability: clinical evaluation. Four tooth-containing blocks were obtained from patients being treated for infraosseous lesions of significant depth as part of their periodontal therapy. We present a rare case of 2 intraneural ganglion cysts in separate nerves of the foot, originating from different joints within the same joint complex. The relative oral bioavailability of ciprofloxacin is significantly decreased when administered with sevelamer hydrochloride or calcium acetate.

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Percutaneous angioplasty of internal mammary artery graft stenosis using the brachial approach: a case report. 25, 751-759) that bind to hapten-mAb complexes in a reaction where conformational changes on the primary antibody are important. Antagonism of stimulation-produced antinociception from ventrolateral pontine sites by intrathecal administration of alpha-adrenergic antagonists and naloxone. Working Party Chronic Leukemia of the European Group for Blood and Marrow Transplantation.

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Developing appropriate delivery carriers that can assist 5-ALA in bypassing the lipophilic barrier to directly enter into cancer cells is a research focus. Evaluation of different immunization schedules for oral cholera B subunit-whole cell vaccine in Swedish volunteers. Microparticle-enhanced nephelometric immunoassay of lysozyme in milk and other human body fluids. Interventions that influence the survival of liver and effector cells by altering their apoptosis are candidates for study in autoimmune hepatitis.

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The objectives of this study were to examine whether elderly Tai Chi practitioners have developed better knee joint proprioception and standing balance control than control subjects. Spatial organization of the N-terminal beta-endorphin tridecapeptide In contrast to this, in Aspergillus nidulans, both processes contribute considerably so that mitotic segregants always have to be tested for their mechanistic origin.

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Lowering of the sum of both these metabolites by palmitate and stearate points to the inhibition not only of pyruvate kinase but also of other enzymes of early steps of glycolysis. Australia and New Zealand Health Policy is a new journal which aims to promote debate and understanding about contemporary health policy developments in Australia and New Zealand. By sequestering endogenous miR-137, we were able to ameliorate the synaptic phenotypes.

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In adults, following acute PSC ablation, synaptic structure and function were not altered. Myogenin acts later in development and plays an essential in vivo role in the terminal differentiation of myotubes. Specifically, we mapped available genomic sequencing short reads from a male and a female polar bear against the reference genome and identify 112 Y-chromosomal scaffolds with a combined length of 1.9 Mb. These changes in ganglioside composition are suggested as new biochemical markers for leukaemic cells. Fate of Croneton (2-ethylthiomethylphenyl N-methylcarbamate) in rats.

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Bronchospasm precipitated by ophthalmic instillations of timolol. Symptoms referred to the neurasthenic syndrome were also frequently seen, such as fatiguability and irritable and hostile feelings.

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Characterization of different plasmid-borne dihydropteroate synthases mediating bacterial resistance to sulfonamides. Absorption of a large dose of orally administered iron in iron-deficient subjects resulted in a somewhat greater amount of diferric transferrin at low saturation and a somewhat smaller amount of diferric transferrin at higher saturations than would have been anticipated by random loading. Individuals with this disorder also have an increased incidence of hypertension, diabetes mellitus, and renal and cardiac anomalies.

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Castration, adrenalectomy and hormone replacement studies show that the amount of iron stored depends directly on circulating oestrogens and is slightly but not significantly decreased, in our experimental conditions, by testosterone. A study was made of the immune status in patients with infectious-allergic bronchial asthma in the phase of clinical manifestations before the onset of exacerbation 2 mos after examination, and in patients with a favorable course of disease without exacerbations during the same period of time. The phase relationships involving the metastable orthorhombic (R(I)) phase and the stable triclinic (T) phase were established for even-numbered carbon atom n-alkanes in the range of 8-20 carbon atoms. UVB irradiation upregulated IL-10 mRNA levels in lymph nodes and spleen only to significant levels in PAF-R-expressing mice.

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Our results indicate that, in liver cancer, the cytotoxic somatostatin analogue AN-238 is a powerful agent that can induce apoptosis, through sst(s) and independently of p53. The results are in agreement with previous observations in the rat and support the view that long-lasting sustained hypergastrinaemia causes trophic changes in the stomach but not in the pancreas or in the intestines. Doctors and soldiers during the campaigns of the Revolution and the Empire. Most of the isolates demonstrated vasopressin receptor antagonist activity in vitro with the new epoxide being the most active of the diterpenes tested.

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Cross-face reanimation of the paralysed face, with a single stage microneurovascular gracilis transfer without nerve graft: a preliminary report. The dependence of degradation on the dosage and the time after irradiation In one method of purification the enzymic activity could be resolved into two fractions after chromatography on DEAE-cellulose. T-cell colony-formation by human lymphocytes in vitro: type of colony-forming cells and effect of preincubation on colony formation Variation in the presence of these latter elements was detected not only between different patients, but also within different samples taken at different times from a single patient and even among different cells of the same sample.

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We describe here the incorporation of hydroxy acids into the precursor peptides in E. The reproductive functions of epileptic females often display alterations.

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Easily interpreted output tables are generated monthly on such variables as completed cases according to treatment series and clinician, number of various procedures performed by clinicians, etc. Shock training and auditory cues associated with shock produce alterations in sleep that can be long-lasting in BALB/cJ (C) mice. Both excreted 3-hydroxydicarboxylic acids (C8-C12) as identified by mass spectrometry. She was intubated and ventilated for the first two weeks of life and developed bronchopulmonary dysplasia requiring corticosteroid treatment.

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The vitreous attachment to the macula can be subclassified into two subgroups, each having specific induced alterations in retinal anatomy. Recent literature continues to support high-resolution CT (HRCT) as being more sensitive than chest radiography in detecting pneumoconiosis. A 9.5-year follow-up of the Kaunas-Rotterdam Intervention Study (KRIS) provided an opportunity to compare mortality patterns and rates in a population from Lithuania, one of the former republics of the Soviet Union, with a population from the Netherlands. Multilocus sequence typing (MLST) is also emerging as a very useful tool for both Bcc strain and species identification. On radiologic examination, hemivertebrae were detected on the thoracal vertebrae.

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Evaluation of neonatal renal disorders: a comparison of excretory urography with scintigraphy and ultrasonography. However, the secular pattern of relative ecological importance between the bryozoan clades Cyclostomata and Cheilostomata is not reflected fully in compilations of generic diversity or within-fauna species richness, and the delayed ecological recovery of the Cheilostomata after the mass extinction at the Cretaceous-Tertiary boundary is missed entirely. The development of these enzyme activities also remains normal in young whose mothers were repeatedly exposed to altitude hypoxia at a simulated altitude of 5 000 m during the whole of pregnancy. Tunneling Electrical Connection to the Interior of Metal-Organic Frameworks.

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Modulation of antioxidant activities and immune response by food restriction in aging Fisher-344 rats. A strong skin-sensitizing potential of the beta-glucanase enzyme was detected, but no other evidence of oral or inhalation toxicity, mutagenic potential, eye or skin irritancy was found. Endobronchial and parenchymal variants are classically described. Mixed evidence offers weak support for a link between PTH, cognition and dementia due to the paucity of high quality research in this area.

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The brain stem was rendered anoxic during cardiac arrest, which caused the respiratory failure. Aspirin has proven clinical efficacy in limiting the thrombotic complications of atherosclerotic vascular disease but its mechanism of action remains unclear. Suppression of plasma-activated factor VII levels by warfarin therapy. This article reviews the differential diagnosis and neuropsychiatric assessment of young-onset dementia, which includes detailed history taking, family history, mental status examination, office-based cognitive tests, and a focused neurologic examination.

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Job-specific applicant pools and national norms for cognitive ability tests: implications for range restriction corrections in validation research. None of these options has emerged as ideal or universally acceptable. To determine the usefulness of color Doppler ultrasound (US) in the evaluation of the response of hepatocellular carcinoma (HCC) to percutaneous ethanol injection (PEI). Segregation and linkage analyses of a large pedigree with hypertriglyceridemia.

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The only histologic feature typical of extruded prostheses was the presence of granulocytes in all parts extruded. According to these results one weed control measure between 27 and 54 days after crop emergence could be enough to avoid any reduction in maize productivity. Instantaneous velocities have been decomposed into periodic mean and turbulent fluctuating components from which estimates of Reynolds stresses within the chamber and mean shear stresses along the wall of the chamber have been obtained.

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Tumor necrosing factor-alpha (TNF-alpha), interleukin-6 (IL-6) and C-reactive protein (CRP) are biomarkers of inflammation and indicators of the immune response to tumors. The significance of visualization of surface features by SEM as a means for differentiating species is not yet known. Procedures capable of inducing the differentiation of authentic articular cartilage to resurface degenerated human joints would be invaluable. Disposition and nephrotoxicity of 3-amino-1-hydroxypropylidene-1,1-bisphosphonate (APD), in rats and mice. UFT has recently entered extensive investigations in North America and Europe.

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Following exposure of CHO-K1 cells to 137Cs irradiation at doses up to 20Gy, a delay in G2 was observed to occur in cells permitted to divide normally, while cells induced to become giants by means of cytochalasin B demonstrated a minimal delay in the transition 2C-8C suggesting that the inhibition of cytokinesis results in modification of one or more cell cycle checkpoints. These results suggest that whole-body FDG PET is an effective imaging modality to screen for metastases from malignant melanoma. The nomenclature and definitions of the major forms of SV were revised and additional categories of vasculitis were included into the classification, by relying on the current trends in the practical use of terms, on the current ideas on the specific features of manifestations of diseases, and on achievements in studying the pathogenesis. Comparison of subcutaneous versus intradermally inoculated murine C-1300 neuroblastoma.

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CAPD is a widely accepted therapy, however, some patients develop complications that can impede continued therapy. Prospective study of normal, early postmenopausal women, initially a double-blind, placebo controlled trial, subsequently an open, controlled investigation. A 26-year-old woman, who had undergone jejunoileal bypass surgery six years previously for obesity, had symptoms of intermittent fever, myalgia, polyarthralgia, and aseptic joint swelling. Twenty-four Vi antigen-specific monoclonal antibodies were produced in this study. For post-infectious, idiopathic or hypercalciuric calculi ESWL was used in the majority of patients after 1988.

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This paper presents our new spectroscopic data on amino acids obtained using FT-IR emission spectroscopy. Because there are no characteristic clinical or roentgenographic findings, aortography is the only definitive method of establishing the diagnosis. A large variety of diseases are present in the ACL-reconstructed group but with very low prevalence rates and low CCIs, indicating that the severity of their illness is limited.

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Single photon emission computerized tomography using a rotating gamma camera needs accurate calibration of electromechanical components, detection system and reconstruction software. Splenomegaly with hypersplenism, hematemesis and melena have been the most frequent clinical manifestations. The effects of ablating the hippocampus and amygdaloid complex on thymocyte number and function also are abolished.