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To investigate expression of midkine (MK) in hepatocellular carcinoma (HCC) and its relationship with HBV infection. A newly developed immunosuppressant, FTY720, has a unique mechanism that is quite different from those of conventional immunosuppressants, and is presumed to be mediated through decreases in the number of peripheral lymphocytes, especially helper T cells. Sublocalization of an ataxia-telangiectasia gene distal to D11S384 by ancestral haplotyping in Costa Rican families. These aspects will be discussed in detail illustrated with appropriate cases. High-affinity binding sites for human 26-kDa protein (interleukin 6, B cell stimulatory factor-2, human hybridoma plasmacytoma growth factor, interferon-beta 2), different from those of type I interferon (alpha, beta), on lymphoblastoid cells.

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We retrospectively reviewed the medical records of all diabetic patients with benign, transient disc swelling who were evaluated at our institution from 1986 to 1992. cerevisiae strain showed sufficient xylose-fermenting ability to be used for efficient ethanol production from glucose/xylose. Understanding of the religious, social, and cultural background is of paramount importance in the management of these patients.

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The changes reached the summit in 10 days and the general living condition of the animals recovered in 60 days. Morquio A syndrome: cloning, sequence, and structure of the human N-acetylgalactosamine 6-sulfatase (GALNS) gene. Oxygen consumption rates of oceanic prokaryotes measured with current methods may be biased due to pre-incubation size filtration and long incubation times both of which can change the physiological and taxonomic profile of the sample during the incubation period. Flavonols, flavone and anthocyanins as natural antioxidants of food and their possible role in the prevention of chronic diseases

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Toward production of jet fuel functionality in oilseeds: identification of FatB acyl-acyl carrier protein thioesterases and evaluation of combinatorial expression strategies in Camelina seeds. The homologous proteins of the two species differ in their mobility.

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The disruption of this motif affects the binding to both these kinases as well as viral replication. Card sorting experiments were performed on the terms in the action and descriptor lexicons, the staff being asked to group words that were related to the same or similar concepts. It suppressed the telomerase activity of the cells in a dose- and time-dependent manner. Amplification-free (referring to enzymatic amplification step) detection methodologies are increasing in biosensor development due to the need of faster and simpler protocols.

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There are several other minor differences in the nucleotide sequence of the Blast-1 and MEM-102 cDNAs that do not affect the predicted structure of the polypeptide product. Channel catfish as an unconventional model for immunological studies.

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The genotype and allele frequencies of both polymorphisms were not statistically different between the HNSCC and control groups. Platelet aggregation (ADP 1 microM/ml) was also carried out pre and post-dialysis.

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Key informants added suggestions about interpersonal strategies (e.g., physician referrals) for center usage promotion but cautioned that a large increase in traffic could not be accommodated without increasing staff size or shifting from a model of individualized service. This interaction of NGF with the complement system may account for the previously described ability of NGF to accelerate the rate of contraction of experimentally induced wounds. Nucleic acid hybridization studies reveal that the origin of the SAIDS-D isolate may reside in Old World monkey (subfamily Colobinae) cellular DNA. Point mutations have been introduced in vitro in a cloned nematode tRNAPro gene.

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Attenuated Salmonella becomes versatile vector in multivalent, multipurpose genetic vaccines. In all these patients karyotype studies were performed demonstrating the chromosomal aberrations. Perirhinal cortex ablation impairs configural learning and paired-associate learning equally. IL-12 receptor deficiency revisited: IL-23-mediated signaling is also impaired in human genetic IL-12 receptor beta1 deficiency. Rosai-Dorfman disease (RDD), a systemic histioproliferative disorder, was first described by Rosai and Dorfman in 1969.

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Single-photon tomographic study of regional cerebral blood flow after stroke: concise communication. In alloxan diabetic mice, contact sensitivity reactions are reduced significantly, and our experiments show that insulin deficiency affects only the activity of the late acting, lymphokine-producing cell and leaves the factor-producing cell responsible for the early swelling reaction unaffected. Ovarian tissue viability following whole ovine ovary cryopreservation: assessing the effects of sphingosine-1-phosphate inclusion. They were localized post mortem and the units discharging at the harmaline tremor frequency were mapped. This study corroborates the Centers for Disease Control guidelines of cost effectiveness in screening prehospital health care workers.

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A putative transposable element was identified that contained two genes, including a transposase ortholog. These cell lines maintained in an IL 3-dependent growth state were converted to lymphokine-independent growth after infection with v-src. Tetrodotoxin suppressed the amplitude but not the frequency of the slow potential change, however repetitive field stimulation in the presence of tetrodotoxin did not reduce further the amplitude of the slow potential changes. This study provides an electrophysiological basis for prolonged circular muscle contractions of the colon, and it emphasizes the pacemaker activity of gastrointestinal smooth muscle as an important site of drug action. Such abrogation of alloreactivity was alloantigen-specific, since p.v.

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The cyanide consumed by this strain is stoichiometrically converted into ammonium. either 400 mg/kg of K-247 or 5 mg/kg of GT-101 (for 7 days consecutively). Both codes are voluntary, are addressed largely to governments and industry, and incorporate both practical guidelines and ethical considerations.

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Glycosylation site-binding protein is not required for N-linked glycoprotein synthesis. The final structure demonstrated a cavity within the core of a four-helix bundle. Of these, 21 cases were diagnosed as membranous glomerulopathy (MGN), 1 as membranoproliferative GN, and 2 as diffuse mesangial proliferative GN. The properties of full-length and mutant peripherins were studied in intermediate filament-less SW13 cells to define regions of peripherin that are essential for initiation of filament assembly. Finally, by immunohistochemical analysis, we have demonstrated the in situ expression of one of the novel MAb-reactive epitopes specific for antigen 85B on the cell wall surface of M.

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Of these, 16 bound to axons only, 8 bound to axons and cell bodies, and 5 bound to cell bodies only. When a prostate cancer is suspected, a new concept, the prostate specific antigen density related to the transition zone volume, has been demonstrated as a very effective mean for prostate cancer early detection in men with PSA levels below 10 ng/ml.

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Each day, for 13 days, wound margins were traced, and the TCC and TCC vehicle groups were treated topically. Finding a substitute material for strontium isotope analysis of burned human remains, reflecting childhood values, is hence of high priority. Mineral and metal contents of 24 wild mushroom species collected from Anatolia were analysed by inductively coupled plasma optical emission spectrometry. Our results suggest that plasma neuropeptide Y does not increase with noradrenaline on sympathetic activation during postural stress both in normals and in hypertensive subjects.

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It was observed that cell mediated immunity as expressed in terms of percentage of blast cells is definitely depressed in leprosy, most in LL and least in TT. Treatment of missing data values in a neural network based decision support system for acute abdominal pain. Dermal fibroblasts seemed to require a growth factor from platelets for growth, but chondrocytes did not.

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Ludwik Rajchman (1881-1965): world leader in social medicine and director of the League of Nations Health Organization. Similar decrease of brain serotonin concentration was observed in both Wi and DI rats 48 h after pCPA treatment.

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The purpose of this study was to investigate the practical feasibility and the psychophysiological effects of biofeedback applied to heart rate variability (HRV biofeedback) in order to increase cardiac coherence in coronary artery disease (CAD) patients participating in a cardiac rehabilitation programme. Also, the amount of GABA released was much larger when the drug was administered by i.p. opening) of a certain fraction of its neighbors and hence, these groups of channels behave as a unit. Use of end-tidal carbon dioxide to predict outcome in prehospital cardiac arrest. Massive black holes most likely grow by a mixture of merging and accretion of gas in their hierarchically merging host galaxies.

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Since the characteristic of metallothionein is by its metal content, we estimated the cadmium concentration in all fractions and it was evident that cadmium peak corresponded only with the peak of radioactive amino acid incorporation to metallothionein. Interpolated conjunctival pedicle flaps for the treatment of exposed glaucoma drainage devices. We analyzed virologic, biochemical, and serologic responses at 3, 6, and 12 months.

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A reproducible, accurate, and automated breast density measurement is required for full-field digital mammography (FFDM) to support clinical applications. LS was obtained from rats with inflammation induced by polyvinylpyrrolidone. It was estimated that ribonuclease of Bacillus pumilus is synthesized post-exponentially, its synthesis is inhibited by inorganic phosphate and is stimulated by actinomycin D, as the synthesis of ribonuclease by Bacillus intermedius.

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The double contrast technique is of particular value in the proximal stomach, where one is able to detect ulcers and masses not recognized on a conventional upper gastrointestinal series. In this study, we examined the effect and potential mechanisms of luteolin supplementation in a carcinogen initiated alcohol-promoted pre-neoplastic liver lesion mouse model. Moreover, RCM precursor could be immunoprecipitated using specific anti-(human MUC2) antisera, indicating that the RCM can be designated rat MUC2. After 4 days of treatment with cimetidine (24 mg/kg/day), adapted oral alimentation generally was well tolerated with normal gastric residues.

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Methanethiol depressed spontaneous dorsal and ventral root potentials, whereas no effects were observed on evoked responses. This review is also meant to serve as a bibliographic resource for some of the controversies of this complex topic.

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Homology with animal cystatins and transient expression in the ripening process of rice seeds. No significant correlation could be estiblished between the observed lipid, protein and haemostatic parameters, and it is suggested that they represent independent phenomena. Influence of prostaglandins F-2 alpha and E-2 on ovulation character and on the state of the ovulated gametes has been studied in rats at the preovulatory period (the preparations have been injected for 3 days, beginning from the 1st day of early proestrus).

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They consisted of two types, i.e., large (LR type) and small (SR type) presynaptic terminals, both of which had round synaptic vesicles and formed asymmetric synaptic contacts. By examining cGMP formation, it was found that 24-hr treatment with GTN but not PETN induced significant nitrate tolerance, which was prevented by parallel treatment with Vit C. The implications of these findings for immunoregulation by Ab:Ag and idiotype:anti-idiotype (Id:anti-Id) complexes, and infection of macrophages by HIV, are discussed. A single-blind study of clocapramine and sulpiride in hospitalized chronic schizophrenic patients. Serum levels of 3-keto-desogestrel after oral administration of desogestrel and 3-keto-desogestrel.

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Some observations on neonatal staphylococcal carriage with special reference to hospital environment. Graft-versus-host disease is an uncommon but serious illness, caused by foreign, immunocompetent T lymphocytes attacking an immunoincompetent host. Recognition of unusual DNA structures by human DNA (cytosine-5)methyltransferase. A longitudinal experimental protocol for the testing and evaluation of this hypothesis is presented.

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This patient survived postoperative renal failure and myocardial infarction, but died 21 months later from another myocardial infarction. In vitro methods for hazard assessment of industrial chemicals - opportunities and challenges. Because many PCOS patients have a propensity to develop dyslipidemia, we hypothesized that the brown adipose-differentiation factor, irisin, and the glucose-dependent insulinotropic peptide (GIP) play a role in the development of PCOS. Accessory ossicle or intraepiphyseal fracture of lateral malleolus: are we familiar with these? Analysis of the fatty acyl composition of phospholipids also showed that the proportions of polyunsaturated fatty acids were reduced relative to saturated fatty acids, indicating peroxidative damage to phospholipids.

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Descriptive statistics and logistic regression models were used for analysis. According to the simulation results, stable control is achievable in the presence of large noise levels and for unknown or variable physiological or technical time delays. In summary, the median filters can improve the quality of volume reconstruction by reducing the interpolation errors and facilitate the following image analyses in clinical applications. The coexistence of other Axis I disorders with bipolar disorder complicates psychiatric diagnosis and treatment.

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DKA associated with excessive intake of weight reducing diets has not been reported previously. A similar result was also obtained with HIV-2 C4 peptomer except that the binding occured only in those of constituents having molecular weights higher than that of trimer. However, each lesson that is learned from this evolving epidemiology will hopefully result in improved surveillance, diagnostic,and treatment and prevention capabilities. A multifaceted assessment of emotional tolerance and intensity in hoarding.

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Component mechanisms of sensitivity and adaptation in an insect mechanoreceptor. Differences in effects of 1-alkanol inhibition, activation by phosphatidylethanolamine and calcium chelation.

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Two month old S and R rats raised on normal rat chow had only small differences in blood pressure and no difference in plasma ANP levels. The antibodies produced by the hybridoma cell lines were characterized by determination of the class of light- and heavy-chain components and by determination of specificity for the cholera toxin subunit. The defect of intestinal calcium transport in hyperthyroidism and its response to therapy.

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Stupor was diagnosed as due to defect of reaction to stimulus of sound, light and touch. Here we show that Xenopus egg extract can initiate DNA replication at specific sites in mammalian chromosomes, but only when the DNA is presented in the form of an intact nucleus. Right coronary ostium agenesis with anomalous origin of the right coronary artery from an ectasic circumflex artery. Among our respondents, the presence of social support was indeed associated with reduced symptom levels for those exposed to moderate housing stressors. Organ blood flows in untreated and saline-treated conscious rabbits and saline-treated anesthetized rabbits were quantified and compared.

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Homocamptothecins (hCPTs) represent a class of new emerging antitumor agents, which contains a seven-membered beta-hydroxylactone in place of the conventional six-membered alpha-hydroxylactone ring (E ring) of camptothecins. A panel of different in vitro assays was used to characterize the biological activities of ALX-0061.

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Everything from simple grafts to sophisticated distant bone flaps has been used. In contrast, lower or similar expression of COX-1 compared to COX-2 was observed in endometrioid, mucinous and clear cell tumors.