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However, our results also suggest that other types of glutamate receptors may play an additional role in mediating the action of this excitatory amino acid on the IGL neurons. Histological sections from all regions of the brain and spinal cord demonstrated a severe, non-necrotizing, subacute, polio-meningoencephalitis.

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This study demonstrates that thymic deletion and the functional impairment of T cells present in the periphery both operate to establish T-cell tolerance to the tumour-associated antigen MDM2. We studies ventricular fluid pressure changes in 26 hydrocephalic children following administration of ketamine. The findings are consistent with the occurrence of intravascular haematopoiesis in the renal medulla in acute tubular necrosis. Validity of thermal dilution technique for measurement of cardiac output in rats.

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Using this technique, local structural information was obtained about mixtures prepared from isolated pig ceramides, cholesterol, and long-chain free fatty acids. Ion pair formation involving methylated lysine side chains: a theoretical study.

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Noradrenaline-induced calorigenesis in warm- and in cold-acclimated rats: the interrelation of dose of noradrenaline, its concentration in arterial plasma, and calorigenic response. A cell line designated OSHU-1 was produced by cell culture of a grade II chondrosarcoma excised as a whole from the public bone of a 59-year-old man. These results suggest that SP has two distinct effects (an endothelium-dependent dilation and a direct constriction) and that the potentiated constriction in the absence of endothelium may be related to the action of thromboxane A2, linked with calcium influx into the smooth muscle cells of cerebral arteries. Changes in J chain and mu chain RNA expression as a function of B cell differentiation.

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Androgens and male mating behavior in rough-skinned newts, Taricha granulosa. Radiation-induced lipid peroxidation and membrane permeability in liposomes. Pentobarbital anesthesia thus has important electrophysiologic implications on the effects of calcium channel blocking agents on chronotropic and dromotropic variables on the heart.

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Determination of low molecular weight heparin in clinical laboratory. These data suggest that impaired cognitive functioning may be a factor in the disability associated with the major affective disorders in addition to the distorted affective component usually emphasized. Histamine could be responsible, because spoiled scombroid fish contain large quantities of histamine. Zinc supplementation treatment of growth retardation and hypogonadism in sickle cell patients. Further study is necessary to determine whether foscarnet, by itself or in combination with other treatment modalities, has a role to play in the treatment of chronic hepatitis B infections in humans.

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This study examined the distribution of the major transplantation antigens on fresh human trachea. The masking of filtration clefts visualized by hrSEM corresponded to the multiplication of slit diaphragms and adhesion of foot processes in the TEM findings, and preceded retraction of the foot processes. Reanalysis of forensic urine specimens containing benzoylecgonine and THC-COOH. Transesophageal Doppler echocardiography evaluation of coronary blood flow velocity in baseline conditions and during dipyridamole-induced coronary vasodilation. On the basis of a biochemical study of thyroid papillary and follicular carcinoma tissue (original focus, its periphery and cervical lymph node metastasis), we endeavoured to determine whether or not there was any Tg in the metastatic lymph node, and if there was, to extract and refine it, and also to determine the biochemical properties of Tg.

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derived lymphoblastoid cell line) serum reacted only with cells of T-A.L.L. Thus, an interference in the rate of nitrogen fixation is possible as a result of nitrate reductase activity. Intergenerational transfers within the family context--motivating factors and their implications for caregiving.

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Hypogeusia, with or without dysgenusia, and hyposmia, with or without dysosmia, followed an influenzal-like infection in 87 of 143 consecutive patients who presented at the Taste and Smell Clinic at the NIH with taste and smell abnormalities. The perspective of activities and interactions was chosen to illustrate, through a nonparticipant observation study, the patterns and utilization of time during a scheduled clinical experience for baccalaureate nursing students.

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Resting-state network analysis suggested that the internetwork connections typically obey the hemispheric lateralization trend and most of the functional connections that disturb the lateralization trend are the intranetwork ones. Anecdotal evidence suggests that some patients suffering from motor neurone disease may request euthanasia because of a fear of choking to death. Influence of diet and obesity on placental amino acid enzyme activities in the rat.

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However, unlike bone marrow-derived professional APC, such as dendritic cells or B cells, little is known about the mechanisms of MHC class II presentation by the nonprofessional APC in vivo. Effect of intestinal surgery on the risk of urinary stone formation.

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In such preparation, microfibrils are made visible within the core of amorphous elastin as well as in regions that are free of elastin. The case is further unusual in that few children with advanced stage neuroblastoma survive long enough to develop second malignant neoplasms. Therefore, the activity is not dependent on chiral interactions between the peptides and the lipid bilayers or the bacterial membranes. During the first month of life, minima in respiratory rates in quiet sleep occurred during the second and third intervals of the night in subsequent siblings, a pattern not seen until three months of age in control infants. Oculo-orbital anatomy and nuclear magnetic resonance: use in ocular growth and fetal pathology

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This effect depends on the duration of the electrical discharge (expressed as the speed of a conveyor belt) and the distance between the electrodes and the membrane. Influence of referral source on return compliance of adolescents. In this study we show that these lncRNAs (Gtl2, Rian and Mirg) are first expressed at the morula stage and gradually restricted to the inner cell mass (ICM) as the embryo differentiates into the blastocyst. Enhancement of spike and wave discharges by GABAmimetic drugs in rats with spontaneous petit-mal-like epilepsy.

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The profuse flow of CSF was believed to be secondary to a wide-open cochlear aqueduct in the first case, and to an abnormal communication between the internal auditory meatus and the vestibule in the second case. Epidemiological study on hepatitis morbidity in dental personnel on the model of the Erlangen university dental clinic One-way ANOVA comparison among groups 2, 3, and 4 showed no statistical significance, whereas group 1 showed statistically significant difference when compared with groups 2, 3, and 4 at 7(th), 14(th), and 30(th) day. In SCCC, p21 expression was significantly reduced compared with squamous cell carcinoma, whereas expression of p27 was similar in both carcinomas.

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However, mean platelet MAO activity was reduced in the subgroup of nonaffective schizophrenic disorders characterized by the presence of auditory hallucinations often occurring in conjunction with paranoid features (that is, the S-2 subgroup). CH without atypia, however, predicted lesser degrees of malignancy as compared to CH with atypia.

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Although these immunosuppressants are known to effectively control ulcerative colitis (UC), some post-OLT patients develop exacerbation of preexisting UC or de novo UC. Cell surface adhesion receptors are probably playing an important role in determining the correct evolution of these processes. A general method for synthesizing enzyme-polymer conjugates in reverse emulsions using Pluronic as a reactive surfactant.

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Adjuvant vinblastine, actinomycin D, bleomycin, cyclophosphamide and cis-platinum chemotherapy was given with maintenance in the first 24 patients and without maintenance (2 months of chemotherapy) in the subsequent 18. These xenoantisera react with antigenic specificities present on the cells of cultured lymphoid cell lines of B type, but not on cells of T cell lines. This tendency was also seen when the pupil diameter was fixed at 3 mm with an artificial pupil. Anti-atherogenic activity of the calcium channel blocker isradipine (PN-200-110): a novel effect on matrix synthesis independent of calcium channel blockade.

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An evaluation of a smoking prevention programme with children from disadvantaged communities. Emphasis is placed on the differing natural history and management of these two unusual lesions in order to expedite aggressive treatment when required.

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Myelination in the CNS of mld mutant mice: comparison between composition and structure. Following a critical analysis of the various complications several alterations in the surgical treatment are suggested. The review of the literature on sleep disorders in epilepsy over the last two decades is presented. Occult blood loss and early diagnosis of colonic and rectal carcinoma Repression of estrogen-dependent stimulation of the oxytocin gene by chicken ovalbumin upstream promoter transcription factor I.

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In this context, a fat-modified diet, physical activity and eumetabolisation in a broader sense are especially important. Berardinelli-Seip congenital lipodystrophy (BSCL) is an uncommon autosomal recessive disorder. Exogenous IL-2, however, restored the ability of spleen cells from iron-loaded mice to generate allo-specific cytotoxicity in bulk culture. Increased levels of UCHL1 are a compensatory response to disrupted ubiquitin homeostasis in spinal muscular atrophy and do not represent a viable therapeutic target. Their endobronchial localization is exceptional, a fortiori in the child.

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U14 snRNA is a small nucleolar RNA species essential for eukaryotic pre-rRNA processing. This study examines if viral protein function/fitness is the major constraint shaping selection of recombination hotspots in replication-competent HIV-1 progeny. In contrast, CEF was equally effective in inhibition of the histamine release by concanavalin A with phosphatidyl serine when the mast cells were treated with CEF prior to or simultaneously with the liberator. Chromatographic and autoradiographic studies suggest that creatinine metabolism in both species involves a single step resulting in the production of methylhydantoin and ammonia.

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This review thus focuses on the development of new classes of small molecule therapeutics to prevent post-surgical fibrosis in the eye, especially in the context of glaucoma filtration surgery. Organocatalytic asymmetric intramolecular aza-Henry reaction: facile synthesis of trans-2,3-disubstituted tetrahydroquinolines.

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To characterize the binding, we have isolated clones from a human fetal liver cDNA library and expressed several fragments comprising either one or both of these sites. Glycosyl hydroperoxides: a new class of potential antimalarial agents. But also without subsequent surgery, it may be performed in vertebral haemangiomas as curative or in malignancies as palliative treatment for compression of the spinal cord or of spinal nerve roots, as demonstrated by some examples. In those studies, however, the concentrations of t-RA were supraphysiological (0.1-10 microM range). Human kidney (HK-2) cells, rat peritoneal macrophages and renal cortical homogenates were exposed to pharmaceutical iron preparations.

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Such labeled neurons were occasionally seen in rats aged 15 days, but not seen at all in rats aged 60-90 days. Columns containing ribosomes translating poly(U) covalently bound with cellulose (solid-phase translating system) were used to study translocation in ribosomes. Lymph node anti-tumour effector cell mechanisms in colorectal carcinoma. Selective mGlu5 receptor antagonist MTEP attenuates naloxone-induced morphine withdrawal symptoms. Patients whose ABR abnormalities commenced with brainstem potentials I, II, or III had small or no MLD and absent or abnormal AR.

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Within the basal subtype, patients show significantly poorer overall survival associated with higher expression of annexin A1. Exocytosis in peptidergic nerve terminals exhibits two calcium-sensitive phases during pulsatile calcium entry. Frequently, it is also instrumental in diagnosing the cause of biliary obstruction in the patient wiht obstructive jaundice.

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The transient zone is formed on the border of the protective and germinative zones. Responses were enhanced when complexes were prepared with a pool of McAbs. The recovery from liver damage was evident at the cytological and physiological level, only the recovery of lobar architecture was incomplete along the period investigated.

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This fact seems to support the hypothesis that an ethnic group with high gastric cancer rate has a higher prevalence of atrophic gastritis and intestinal metaplasia in the older age groups, and offers additional evidence for the association of chronic inflammatory changes of the gastric mucosa with malignant gastric cancer. Age-related quantitative changes in enzyme activities of rat brain.

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Although the underlying mechanisms remain unclear, the accompanying reticulocytosis implies that erythrocyte lifespan in the circulation is shortened. Conservation implications of the mating system of the Pampa Hermosa landrace of peach palm analyzed with microsatellite markers. So far, a complete structural determination has not been carried out on any of the titin modules. Surgical possibilities of restoring the impaired functions of sclerosed urinary bladder in patients with spinal cord injury

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Compared with robust older adults, older people with frailty have the highest risks of mortality, followed by older people in the pre-frail phase. This process underlies representation of subjective meaning of sensory characteristics of the stimulus. In contrast, no conclusion can be deduced from the available studies on the role of central dopaminergic systems in the control of proceptivity and receptivity, the two main components of female sexual behavior. Human engineered heart tissue as a model system for drug testing. Methodology followed that of the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE).

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Barriers to access for severe acute malnutrition treatment services in Pakistan and Ethiopia: a comparative qualitative analysis. To investigate adults with Type 2 diabetes mellitus (DM) in a rural area of Mexico in order to explore their knowledge and beliefs regarding diabetes. American Academy of Pediatrics Committee on School Health: Qualifications and utilization of nursing personnel delivering health services in schools. Samples were measured using tandem mass spectrometry (LC-MS/MS). The use of a cartoon rating scale as a measure for the humor construct.

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Lysophospholipid flipping across the Escherichia coli inner membrane catalyzed by a transporter (LplT) belonging to the major facilitator superfamily. Because the histopathologic scheme is based on results of commonly available stains, it could be easily adopted for use in other institutions that could further evaluate its usefulness as a prognostic tool. The platelet population of man and rat can be divided into two classes of about equal size on the basis of presence/absence of an acid phosphatase which acts on para-nitrophenylphosphate (a PNPase), at pH 5. The latter one is then assayed after partial purification on poly(rI):(rC)-Sepharose or poly(rG)-Sepharose.

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Nondissociating cationic immune complexes can deposit in glomerular basement membrane. Our findings indicate that interference with either absorption or metabolism of a pharmaceutical can result from the vehicle used to administer it. In contrast, N-type but not L-type calcium channel antagonists inhibited axonal dynorphin release. Further studies indicated that they are functionally redundant and epistatically interact to control the transcription of GLS genes. Over-expression of osteopontin in non-small cell lung cancers: its clinical significance

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We investigated the effect of cyclosporin, as well as minoxidil, testosterone, estradiol and corticosteroid on the hair growth on the hairy part of nude mice. The clinical data of 746 breast cancer patients (all female, aged from 33 to 80 years with a median of 46 years) received radical or modified mastectomy between 2001 and 2011 was analyzed retrospectively. The mode-I plane-strain fracture toughness values of eight posterior restorative composite materials were determined using straight-sided chevron-notch short-rod specimens and a special loading module. The use of inhibitors for alcohol dehydrogenase and aldehyde dehydrogenase clearly showed that the observed inhibition was a direct effect of ethanol itself.

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The NBT test is a non-specific test of neutrophil membrane stimulation which has application to the study of neutrophil function, particularly in the septicaemic patient. Increasing evidence suggests that chronic psychosocial stress may increase oxidative stress, which in turn may contribute to aging, and etiology of coronary diseases, cancer, arthritis, etc. The evidence suggests that adrenal renin plays a role as a local hormone in regulating aldosterone production by the zona glomerulosa cells. Postmarketing surveillance for neurologic adverse events reported after hepatitis B vaccination.

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Clinical and follow-up data of 82 patients with cervical esophageal carcinoma undergone surgical treatment in Henan Provincial Cancer Hospital from Dec. The unknown function of these pigments was elucidated by spectroscopy and site-directed mutagenesis. The stability of thyroglobulin obtained after in vivo or in vitro labeling of thyroids from rats kept chronically on an iodine-poor diet (about 30 micrograms I/kg) has been studied by sucrose gradient density centrifugation. Long acting non-depolarizing neuromuscular blockade is useful in many clinical circumstances, especially during surgical procedures. The subcutaneous (s.c.) injection of sheep red blood cells (SRBC) without adjuvant into mice preferentially induced delayed hypersensitivity (DH) reaction, as measured by footpad swelling, while intraperitoneal (i.p.) measured by the haemagglutinin test.