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Influence of secreted frizzled receptor protein 1 (SFRP1) on neoadjuvant chemotherapy in triple negative breast cancer does not rely on WNT signaling. The indicators for symptom scoring were nasal obstruction, facial pain, postnasal drip, anterior discharge, and anosmia/hyposmia. This study establishes the presence of immunoglobulin G in the intraglandular colloid at levels that are of the order of 10 micrograms per mg of colloid. Acute care skills can be validly and reliably measured using a simulation technology. At the scene the incident is classified according to the number and degree of injury of the victims.

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LBP was detected at low concentrations in peritoneal fluid of healthy wild-type mice, and the local LBP levels increased rapidly upon induction of peritonitis. Since ethanol elimination rates were similar, this suggests that in the convulsive state the distribution of ethanol to the periphery is severely inhibited. Moreover, the mutant secreted arabitol under these conditions and, in contrast to the wild-type, featured enhanced expression of enzymes involved in L-arabinose catabolism as well as of extracellular glycosyl hydrolases involved in degradation of the plant cell wall polysaccharide L-arabinan. A remarkable finding was that IGF-I induced formation of multinucleated cells (MNC). Ability of cyclophosphamide in the absence of cross-linking activity to exert the immunomodulatory effect required for the cure of mice bearing a large MOPC-315 tumor.

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Small angle neutron scattering (SANS) combined with deuterium labelling makes it possible to define the positions of specific components within a complex while small angle X-ray scattering (SAXS) provides more precise data on the overall shape. The cell lines were obtained from nonvirus-treated cultures, are nonleukemic, maintain a normal karyotype, and form colonies showing granulocyte maturation when plated in soft agar.

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The cytogenetic status of bone marrow stromal elements obtained from six patients with Ph1-positive chronic myelogenous leukemia (CML), two in blast crisis, was studied in vitro utilizing the potential of marrow to form surface-adherent colonies morphologically compatible with mesenchymal elements. Delecting these oncoproteins may provide a basis for development of truly sensitive and specific markers that can be used to detect cancer at an early and curable stage.

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Previous work on classical olfactory learning and memory in flies has suggested at least four distinct phases of memory consolidation. Acetylpromazine, chlorpromazine, and promazine HCl were ineffective.

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Activity of ofloxacin and pefloxacin against Mycobacterium leprae in mice. Bony bridges along the sides of the terminal phalanx of the great toe occur not only in acromegaly but also in one third of cases with peripheral signs of diffuse idiopathic skeletal hyperostosis. Repetitive correlated activation of pre- and postsynaptic neurons induced long-term potentiation (LTP) of synaptic transmission among hippocampal neurons grown on a layer of astrocytes (mixed cultures) but not among neurons cultured in glial conditioned medium. Reduced uptake and incorporation of 3H-thymidine in Fanconi anemia fibroblasts. The contribution of sociological research to socio-medical knowledge

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Recent studies demonstrated that Ang-(1-7) exerts a vasodilatory and antiproliferative effect via stimulation of the Mas receptor and inhibition of the effects of angiotensin-type 1 receptor stimulation by angiotensin II. Microcirculatory lesion in chronic overheating is caused by irreversible disorders of blood circulation, secondary hypoxic damage of organs and tissues with their functional failure. The results obtained revealed that subjects in the tension-type headache group got significantly higher scores on neurotic subtests (hypochondriasis, depression, hysteria) than subjects in the control group. Analysis of relationships among hypnotic susceptibility, personality type, and vividness of mental imagery.

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Synthesis of steroid-sulfatase-related polypeptides and steroid sulfatase activity were not detectable in fibroblasts from four patients with X-linked ichthyosis. This review will concentrate on the extracardiac manifestations of two opposite, but intimately related, pathophysiologic processes that disturb vascular integrity: namely, thrombosis and hemorrhage. But new data showed that even during more prolonged treatment the correction of anaemia does not have a major detrimental effect on renal function. To study the effects of other mutations in CDK4, we generated a panel of 18 CDK4 mutants using Charged-to-Alanine scanning mutagenesis, and investigated the p16-binding capacity of these mutants to identify novel sites involved in p16 binding.

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Interleukin-1 is a paracrine growth factor for cultured fibrosis-derived kidney fibroblasts. The sole inclusion criterion was the presence of signs and symptoms of an alcohol withdrawal syndrome. The present experiments were undertaken to determine whether a similar change in phosphatidylinositol metabolism occurs during in vitro lens fiber formation in cultured explants of embryonic chicken lens epithelia. Cell mediated immunity in children with scar-failure following BCG vaccination.

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DTI and functional MRI (fMRI) were applied at 1 Tesla for visualization of neural pathways and examination of sensory functions of a patient with severe TBI. For this purpose, adult rats chronically treated with metformin in adolescence or in adulthood were inoculated with Walker 256 carcinoma cells. Part of the delay in reaching the full quantum yield of CO2 fixation could be attributed to the need to build up pools of photosynthetic intermediates to high enough levels to support steady rates of CO2 fixation.

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From uncertain beginnings over four decades ago, heart transplantation is now the definitive therapy for end-stage heart failure. A marker of human foetal endoderm defined by a monoclonal antibody involves Type 1 blood group chains. Proceedings: Anatomical variations in the origin of the posterior cerebral artery demonstrable by carotid angiography and their significance to the direct surgical treatment of posterior communicating aneurysms. Clear differences were noted between rats which responded well and rats which responded poorly to therapy by all techniques. Lesions progressed from erosions to ulceration within 36-72 hr of feed deprivation, and by 84 hr of feed deprivation ulcers had developed thickened, raised margins.

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In cultures from CVI patients with no detectable circulating B cells, little immunoglobulin (Ig) was produced following anti-CD3 stimulation. Influenza A neuraminidase antibodies in children and young adults studied by serum absorption. Effects on skylight at South Pole Station, Antarctica, by ice crystal precipitation in the atmosphere. Sulfhydryl and disulfide stainings in amyloids of skin-limited and systemic amyloidoses.

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Predicting response to antidepressants: demographic and personal history variables. Hypertension treatment trials in dialysis patients should be performed to appropriately inform treatment decisions.

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Ultrastructure of composite tumours consisting of giant cell fibroblastoma and dermatofibrosarcoma protuberans. Hydrops-ectopic calcification-moth-eaten skeletal dysplasia (Greenberg dysplasia): prenatal diagnosis and further delineation of a rare genetic disorder.

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We present the first case of a young woman with primary infertility and essential thrombocythemia who had uneventfully delivered a healthy boy in the fortieth week of pregnancy. We believe that adults may also benefit in some circumstances, as evidenced by the case of a 22-year-old man who underwent successful operation after having initially undergone pulmonary artery banding for transposition with ventricular septal defect in 1967 when he was 5 months of age.

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We compared the clinical presentation and survival rate, together with the radiologic, histologic, and immunostaining (including p53) findings, with strong emphasis on the similarities. Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS.

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The bactericidal activity of SM-1652 was compared with that of cefoperazone. By participating in the PPS, the SR has collected the most recent data on HAI and antimicrobial use in acute care hospitals. The Inhibitory Efficacy of Methylseleninic Acid Against Colon Cancer Xenografts in C57BL/6 Mice. Urinary desmosine excretion did not change following A1PI infusion. In conclusion, the radon gas concentration alone does not provide adequate information on the effective dose.

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In addition, bone resorption should be reduced during menopause with estrogens and gestagens, in the case of a receptor-positive breast cancer with tamoxifen, and after menopause with raloxifene or a bisphosphonate. While the glomerulus is one of the major targets of lupus inflammation, little is known about the cytokine expression in glomeruli. In addition, NC produced a significant increase in subendocardial blood flow, which resulted in an increase in the endocardial-epicardial blood flow ratio (endo/epi).

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The sociological theory proved capable of explaining most of the variation in inter-shift differences in accident rates, and, when tested statistically, appeared to have greater explanatory power than competing hypotheses. Monocyte-derived HLA-G acts as a strong inhibitor of autologous CD4 T cell activation and is upregulated by interferon-beta in vitro and in vivo: rationale for the therapy of multiple sclerosis.

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The shortterm use of the apparatus is intended to provide, in addition to functional substitution of the organs, the best possible conditions for the regeneration of damaged organs. Temporal changes in dissolved 137Cs concentrations in groundwater and stream water in Fukushima after the Fukushima Dai-ichi Nuclear Power Plant accident. The ovine pars tuberalis: a naturally occurring source of partially purified gonadotropes which secrete luteinizing hormone in vitro. The morphological, histochemical and biochemical changes in the liver of rats challenged with a single intraperitoneal injection of the toxin of lupinosis were investigated.

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Elaeagnus strains, and to a lesser extent Alnus strains, have gained and lost many genes to adapt to a wide range of environments and host plants. Cloning and expression of cDNA encoding 25-hydroxyvitamin D3 24-hydroxylase.

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Aqueous two-phase systems: a novel approach for the separation of proteose peptones. Phosphorylation of Gab2 occurred in wild-type, but not Lyn-deficient, G-CSFR-transfected DT40 B cells. Drug release from Gelucire 50/13 matrices took place principally by erosion, although the process was dominated by swelling and subsequent disintegration of the matrix, rather than simple dissolution of the base as was found for Gelucire 55/18. An update on the epidemiology of knee and hip osteoarthritis with a view to prevention.

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Old rats exhibited decreased arterial oxygen tension when compared to young rats after hyperoxia exposure. The aim of the present study was to establish the pharmacokinetic parameters of benzylpenicillin and cloxacillin administration in patients receiving high-dose benzylpenicillin or cloxacillin therapy by continuous infusion. Six of the pit type were observed, a group of 3 on each side of the oral sucker. Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases.

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We also derive the invasion reproduction numbers that determine whether or not a disease can invade into a population in which the other disease is endemic. Whether the display medium--film versus cathode ray tube (CRT)--affects observer performance during interpretation of computed tomographic (CT) images is an important research issue in these times of implementation and growth of picture archiving and communications systems in radiology. Evaluation by contrast-enhanced electron beam computed tomography of myocardial perfusion and tissue characteristics in congenital aortic stenosis. Our results demonstrate that laquinimod suppresses inflammation through down-regulation of inflammatory cytokines and arrest of leukocyte extravasation and thereby could attenuate disease activity in RRMS patients.

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Two peptide chain elongation factors from Halobacterium cutirubrum were purified nearly to homogeneity. Implantation of lyophilized xenogenous cartilage into bony pocket of parodontitis profunda On the basis of the Ht the subjects are divided into three groups. The groups did not differ on clinically normed scores on the IGT.

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The effects of schistosomiasis on spontaneous play activity in black schoolchildren in the endemic areas. Characterization of proliferating cells in transient abnormal myelopoiesis: ultrastructural and immunocytochemical study.

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The soluble intercellular adhesion molecule-1 baseline serum level is higher than normal in infants presenting congenital cardiac defects. Ischemia burden in stable coronary artery disease does not effectively identify revascularization candidates. These results suggest that semaphorin III functions to pattern sensory projections by selectively repelling axons that normally terminate dorsally. In order to increase the titer of S-3HB, a fed-batch fermentation based on pulse feeding of ethanol as a carbon source was performed, and a final S-3HB titer of 12.0g/L was achieved. Isolation and properties of the pigment-protein complex (protochlorophyllide - holochrome) from etiolated leaves of corn sprouts

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Thrombin clotting time and fibrin polymerization in liver cirrhosis. Due to its involvement in varied neuromodulatory processes, the chemokine-ligand/receptor-network is a key element of secondary lesion cascades induced by SCI.

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Antigens of the HLA system (loci A and B) in patients with cutaneous lupus erythematosus and circumscribed scleroderma CORM-2 remarkably accelerated the re-endothelialization 5 d later and inhibited neointima formation 28 d later.

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The muscular and connective coat of the duct is provided with fluorescent globular and varicose structures, of various sizes and colours, which become numerous in the duct branches. Alfentanil was given for analgesia and suxamethonium for muscle relaxation. Fluorescence in situ hybridization on paraffin section showed a translocation involving the EWSR1 gene region. We assessed the regulatory roles of miR-26b on the phosphatase and tensin homologue (PTEN)/PI3K/AKT pathway and the relationship between miR-26b and the metabolism of human obese subjects. Editorial: Pharmacist membership on hospital usage review committees.

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This paper presents an overview of what is known about this vital component of home care and suggests policy and research implications. Characterisation of the Bax-nucleophosmin interaction: the importance of the Bax C-terminus. Spontaneous tooth eruption after alveolar cleft osteoplasty using tissue-engineered bone: a case report. With a view to determining whether production of Th2 cytokines, IL-4 or IL-10, is responsible for the inability of mice to resolve infection with Mycobacterium tuberculosis, mice with targeted disruption of their IL-4 or IL-10 gene were compared with wild-type mice in terms of their ability to defend against an M.

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When an immediate cause is not obvious, repeated examination should be performed because time may reveal a cause of the symptoms. In recent years the issue of patient safety has been the subject of detailed investigations, particularly as a result of the increasing attention from the patients and the public on the problem of medical error. Postoperative nerve irritation syndrome after epidural analgesia in a six-year-old child. This meant that the Burmese in Australia, already under stress arising from cultural differences, were prevented from developing the extensive internal social support systems that characterise other major ethnic groups. An analysis of cavities within the proteins shows that the extremophile proteins are more closely packed than the mesophilic one.

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For the posterior method the method error within a session was about 0.2 cm H2O/l/sec at a flow rate of 0.2 l/sec. However, (1)H magic-angle spinning (MAS) nuclear Overhauser effect spectroscopy (NOESY) indicates that in the presence of cholesterol the peptide has greater penetration into the bilayer. Meta-analysis of the time-course of brain volume reduction in schizophrenia: implications for pathogenesis and early treatment.

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Ovarian hyperstimulation syndrome with minimal ascites and massive pleural effusion: report of a case. Co-registration of dedicated breast CT and PET/CT images can be performed rapidly and reliably using the DD method. This variation shows no significant correlation with the strengths of the mutant phenotypes when the strains are heterozygous with a Ubx null mutation.