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The patients were given a nutritional score, and on the basis of that score were described as malnourished or normal. Furthermore, IAV restriction was apparent as early as 3 h postinfection, and experiments in the absence of protein biosynthesis revealed that the nuclear import of viral ribonucleoprotein complexes (vRNPs) was already blocked in the absence of PEPD.

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1,2-Diacylglycerol may initiate cardiac hypertrophy, probably by activating protein kinase C. Human cytomegalovirus (HCMV) establishes a latent infection in hematopoietic cells, from which it can reactivate to cause significant disease in immunocompromised individuals. Comparison is made between numbers of fits and estrogen, progesterone plasma values during the menstrual cycle of women with epilepsy.

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This problem is compounded by the development of cross-resistance to other useful chemotherapeutic agents which severely limits treatment alternatives. Participation of serotonin in development of morphine dependence in mice and rats. Hypertensive reaction after argon laser trabecular retraction in the treatment of open-angle glaucoma Hypoxia modulates early events in T cell receptor-mediated activation in human T lymphocytes via Kv1.3 channels. Is the plasma ACTH concentration a reliable parameter in the insulin tolerance test?

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An analysis was made of cyclophosphamide action on epithelium of the gingival mucosa, periodontal ligament, alveolar osseous tissue, connective tissue situated between the bone and enamel, cementum, dentin, and dental pulp. This study was designed to investigate endothelial and vascular smooth muscle function in coronary arteries of Ren-2 transgenic rats. Since the results obtained at short intervals after training varied depending on the drug and route of injection, the impairment produced by subcutaneous cycloheximide at 10 min after training cannot be attributed to inhibition of cerebral protein synthesis.

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In this study we analyzed the underlying mechanisms with regard to STAT5 activity. Two hundred seventy-six term-born singletons conceived by ICSI and 273 matched spontaneously conceived singletons at the age of 5.5 years. Transient global amnesia secondary to herpes simplex viral encephalitis.

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Cleavage efficiencies of model substrates for ribonuclease P from Escherichia coli and Thermus thermophilus. Using thin-layer chromatographic and alkaline hydrolysis procedures the reaction product was identified as alkyl-dihydroxyacetone phosphate. Simultaneous investigation of the bacterial flora of a soluble oil in use as a metalworking fluid and of the skin of machine operatives exposed to that soluble oil did not support the hypothesis that bacteria in soluble oil emulsions colonise the skin and either initiate or maintain the dermatitis associated with soluble oil exposure.

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The discordant STA was accompanied by discordant alternation of the repolarization phase of MAP. Taurolidine peritoneal lavage as prophylaxis against infection after elective colorectal surgery. The contribution of the circle of Willis and cerebral cortical anastomoses to the maintenance of adequate blood supply into the involved hemisphere was analysed.

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Students assigned to the intervention received a four session behavioural treatment programme administered individually by a health educator. Five patients had an average improvement of more than 21 points on the Hamilton Rating Scale for Depression and six had an average improvement of seven points. For each mole of S2O4(2-) oxidized to 2SO3(2-) by the enzyme-catalyzed reactions at 25 degrees and pH 8, 1 mol of H2 (1 mol of ethylene for acetylene reduction) and two protons are produced.

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The data obtained are important for the construction of an adjuvant formulation for synthetic immunogens capable of inducing genetically unrestricted immune responses. Three of the transforming dyes (Blue 2, Green 2024, Red 4) did increase tumor incidence and/or mortality in at least one strain of hamster. Each locus was found to code for a population of proteins heterogeneous in both charge and m.w.

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Blood pressure was measured simultaneously and in the same arm by auscultation of the fossa cubitalis (Korotkoff I, IV, and V), by an automated device with a microphone over the brachial artery (equivalent to Korotkoff I and V), and by graphical analysis of these microphone signals (equivalent to Korotkoff I and IV). Prevalence of this disease may be increasing in some regions of Texas. These animals provide a model for the in vivo study of GST modulation of carcinogenesis and drug toxicity. Given the long-range dispersal capabilities of raptors, this pattern suggests that population-specific habitat preferences, corresponding with habitat breaks between eastern and western slopes of the Sierra Nevada, and/or regionally variable population densities limit migration between the Mediterranean habitat of central California and the xeric habitats of southern California and interior west. The hand preference of college students correlated significantly with the writing hand of their biological parents but not that of their stepparents.

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The present study shows that proximal tibial lengthening by DO in CPT can be safely performed if the proximal tibia is not dysplastic and has not been lengthened previously and that lengthening at a dysplastic proximal tibial segment or at a previously lengthened segment renders delayed healing and may require additional procedure(s) to promote bone healing. As regards the final outcome these incidences differ significantly.

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Regulation patterns were diverse and comprised ipsi- and/or contralateral up- and down-regulation with or without topical association to impeding cell death. Before successfully inhibiting a saccade, beta-band power (18-38 Hz) in the lateral PFC and alpha-band power (10-18 Hz) in the frontal eye field (FEF) increased. Cardiac hypertrophy in aryl hydrocarbon receptor null mice is correlated with elevated angiotensin II, endothelin-1, and mean arterial blood pressure. We believe this technique decreases the possibility of early and late restenosis and recommend it for patients requiring carotid endarterectomy.

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Establishing predictors of quality of life (QoL) in individuals with inflammatory bowel disease could help to identify those patients who are most likely to experience poor QoL and to target therapeutic interventions appropriately. We investigated the effects on PPI of different models of limbic epileptogenesis (repeated stimulation of the basolateral amygdala, treatment with pentylenetetrazole, injection of kainate). These results indicate that the persistence of glucose residues on high-mannose oligosaccharides may be responsible for the inhibition of fusion. Semiautomated 14C-thymidine incorporation assay for in vitro screening of anticancer drug. In Iranian Kurdistan, a founder effect appears to be partly responsible.

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Because of the risk of exacerbating metrorrhagia and considering the high morbidity associated to emergency hysterectomy, we decided medical treatment with a depot GnRH agonist (leuprolide acetate 3.75 mg IM monthly). Analysis on the molecular mechanism of globin gene expression in phenotypic variants of cultured Friend leukemia cells. The ratios of QUIN:KYN, QUIN:KYNA, KYNA:KYN and 3HAA:AA revealed that QUIN levels were significantly higher than KYN and KYNA, supporting increased neurotoxicity.

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FSGS is the most common primary glomerular disease underlying ESRD in the United States and is increasing in incidence globally. Successful pregnancy and cesarean section in patients with mitral valve prostheses are possible with this regimen. The urinary excretion of C4--C10-dicarboxylic acids (succinic, adipic, suberic and sebacic acids) and the antiketogenicity of adipic acid have been studied in ketogenic-stimulated rats in three biochemically different states: diabetes, fat-feeding (long-chain monocarboxylic acids) and feeding of hexanoic acid (short-chain monocarboxylic acid). Performing a complex intervention study in palliative care proved to be feasible.

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Method for the accelerated treatment of microsporosis of the scalp Concanavalin A-sepharose affinity chromatography of axon plasma membrane proteins. They work under conditions of extreme stress, and burnout often results. Endothelial origin can be established by a specific immunohistochemical staining, factor VIII antibody. No enzymatic method for the detection of these compounds has yet been reported.

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Type 1 diabetes mellitus is frequently associated with autoimmune thyroid disease (ATD). Such glasses should have no significant absorption in the visible range. The number of molecular components as well as starting values of the positions and the widths of the peaks must be choosen as input for each type of pattern. Our in vitro data warrant further investigation and may provide the basis for nilotinib-supplemented conditioning regimens for allo-SCT in advanced-phase CML. In 1988, 100 12- to 13-year-old children from two neighborhoods in Montevideo with different standards of living were examined.

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A straightforward method for calibration of the quality factor is presented, along with an analysis of the propagation of measurement uncertainties. T and B cells continually migrate around the body by recirculating between blood and lymph via lymphoid tissues. Furthermore, the ease with which to microinject nuclei compared to the technically demanding transgenesis procedure with variable outcome should facilitate more laboratories to use transgenic Xenopus laevis for functional studies in vivo.

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These data suggest that the peptide acts on the diluting segment of the ascending limb of Henle and also at the distal nephrons, findings which support data obtained in stop-flow experiments. The left regional wall motion is appreciated from the comparison between real systole and theoretical systole. Whole venom induced local oedema after subplantar injection and produced relaxation of the rat uterus in vitro.

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A longitudinal study of body weight and body fat changes in Antarctica. Taken together, these results indicate that selective inhibition of prostaglandin signaling could favorably impact aseptic loosening beyond its direct effects on PGE2 synthesis, in that it inhibits downstream pro-inflammatory/pro-osteoclastic cytokine production. Secondly, pretreatment of those immunocompromised animals with interleukin 1 improves immune function.

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Subjects read and recalled a series of five short stories in one of four plot and style combinations. Non-lymphoid accessory cells in the cutaneous infiltrate of B cell lymphomas. Preliminary results show good correlations with spectrophotometric readings. Treatment involves removal of the foreign body if possible (endoscopically or surgically), drainage of the abscess (radiologically or surgically), and appropriate antibiotic therapy.

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During differentiation, stem cells undergo a series of discrete steps, governed by a large number of different genes. During this germ cell rearrangement, the components of the homophilic cadherin adhesion complex, DE-cadherin, Armadillo and alpha-catenin, accumulate along the border between the oocyte and the posterior follicle cells. Nine patients had vessels at the UPJ located laterally or anterolaterally, posterolaterally, or medially and laterally. One third of the neurones recorded decreased their background firing level and or excitatory components of the reactions to reinforcement and conditioned light flashes.

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Value of the QRS complex in assessing left ventricular ejection fraction. The association between the renin-angiotensin-aldosterone system and arterial stiffness in young healthy subjects. Mice immunized with bovine CII respond mainly to other peptides, located in the CB11 fragment around amino acid residues 256-270. This report documents in thorough detail for the first time the sequential antibody changes associated with successful occlusion therapy.

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Data of the analysis are compared to the data reported in the literature. When 125I-T3 of low specific activity (50 muCi/ug) was used as a tracer, free T3 fraction measured simultaneously with free T4 fraction tended to be higher than that measured with a single tracer.

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Immunization with class I human histocompatibility leukocyte antigen can protect macaques against challenge infection with SIVmac-32H. Random walk calculations for bacterial migration in porous media.

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In the long-term (1-month) confinement and crowding, higher plasma cortisol levels and acetyl s-EP concentrations than in the control group were found. We reviewed the medical records of all patients over 16 years of age admitted to the hospital from January 1994 to December 2005 where cocaine abuse was recorded in their clinical history. Therefore the results are not immediately transferable to human. We thus propose that Sclerotinia antagonizes ABA biosynthesis to suppress host defense by manipulating the xanthophyll cycle in early pathogenesis. The artifact appeared in both the phase and frequency encoding direction as parallel lines or ringing adjacent to borders or tissue discontinuities.

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The increased signal intensity of bone marrow after radiation showed no difference in short and long duration between radiation therapy and MR examinations, indicating that bone marrow signal intensities were increased in NPC patients whether or not they had radiation myelitis. Serum concentrations of sex hormone-binding globulin (SHBG), corticosteroid binding globulin (CBG), ceruloplasmin, lipoprotein A and liver enzymes were measured in 30 postmenopausal women treated with 2 mg micronized 17 beta-estradiol daily and micronized progesterone orally in doses of 50, 100 and 200 mg daily, as progestogen supplementation.

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Epididymitis was clinically observed only in one male goat although under six presented macroscopic lesions. The influence of the gut microflora on protein synthesis in liver and jejunal mucosa in chicks. Furthermore, these results provide important information for the identification of other cathepsin D genes in various fish species. GmNRT2 is related to high-affinity nitrate transporters in the eukaryotes Chlamydomonas reinhardtii and Aspergillus nidulans, and to putative high-affinity nitrate transporters in barley and tobacco.

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Desaturation was associated with reduced negative ITP or respiratory movement in three patients and with increased negative ITP or respiratory movement in four patients. Steroidogenic characteristics of in vitro cultured epididymal epithelial cells of the rat. Carcinogenicity of N-nitroso-3,4-dichloro- and n-nitroso-3,4-dibromopiperidine in rats. All patients with peroneal bypass grafts had healed wounds within a mean follow-up period of 17 months.

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Traditional methods of measuring wound strength have often ignored one of the most important variables, i.e., wound surface area. This case study suggests that interstitial pneumonia as a result of DRA should be considered when dyspnoea and reticular opacity of the lung are observed in patients undergoing long-term dialysis.

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From a UK healthcare perspective, ranibizumab provides greater health gains with lower overall costs than aflibercept in patients with VI due to DME. To the best of our knowledge, through immunohistochemical staining methods, we were the first to identify that Egr1 is more highly expressed in AIPC clinical specimens than in androgen-dependent prostate cancer (ADPC).

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Preclinical studies found evidence for both tumor promotion and suppression, though the majority of studies predominantly examined tricyclic antidepressants (TCAs), with 1 report suggesting that TCAs with a nitrogen atom in the central ring are genotoxic. The study demonstrates for the first time that the NRO can contribute to vagal control of pancreatic endocrine function, although the exact circuitry and neurotransmitters involved in this response remain unknown.

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Supramolecular synthesis of 3-indolyl-3-hydroxy oxindoles under neutral conditions in water. Intraluminal changes in retinal vessels were studied by electron microscopy. Clinical staging of chronic myeloid leukemia (CML) distinguishes between chronic phase (CP-CML), accelerated phase (AP-CML), and blastic phase (BP-CML), reflecting its natural history in the absence of effective therapy. Increase of delayed rectifier potassium currents in large aspiny neurons in the neostriatum following transient forebrain ischemia.

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Dissociation of thrombin generation and platelet secretion in diabetes mellitus. We herein amplify on the results of this trial to assist patients and physicians in reaching individualized decisions. Survival in intensive care of patients with chronic obstructive bronchopneumopathy and acute respiratory failure undergoing mechanical ventilation. Some technical skills required and learned during residency training are not often used in primary care. The molecules assayed were related to quinone, nitroheterocycle, and iminium chemical families.

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On the other hand, when the 4-day-old culture cells in the rolling round bottle were inoculated with virus suspension and when 100, 500, or 800 ml of maintenance medium was added to each bottle, there was little difference in virus titer obtained among the culture bottles. Isolation and properties of dehydroepiandrosterone sulphotransferase from human foetal adrenals. Because these rules are based on previous anatomo-embryological findings, the normal development of the conus and the truncus is briefly analysed. However, a predictive relationship between the FcRn binding interaction of IgGs in vitro and their pharmacokinetics in vivo broadly across mAbs remains elusive.

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Altered glucose metabolism in intact and tumor bearing rats subjected to local hyperthermia. The final of the four articles provides advice on writing a dissertation. Blocking the apical secretory pathway by nocodazole or colchicine had no effect on either parameter. As the Par3/aPKC complex has a role in establishing cellular polarity and division orientation in other systems, we explored its potential function in the developing mouse embryo. To investigate the use of four ketamine-based anaesthetic combinations in wild badgers.