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This trace DMBA was considered to be the cause of the development of atypical epithelial cells, inducing ductal carcinomas. These data suggest that nasal polyposis involves deregulated cell growth, using gene activation in some ways similar to a neoplasm. Articular cartilage proteoglycan content was reduced after 4 weeks of trans-stifle external skeletal fixation as determined by loss of alcian blue (AB) histochemical staining.

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A combined radioimmunoassay for glucagon and insulin in biological fluids is presented. Postictal MR findings are analyzed in the context of MR morphological differential diagnoses. Prenatal karyotyping using fetal blood obtained by cordocentesis: rapid and accurate results within 24 hours. Patients given propofol were more elated and continuously less anxious than those given methohexitone from 1 to 4 h after anaesthesia (54.3, SEM 1.1 vs. A short review of established manual methods for determination of key components of the plasma proteolytic enzyme systems as well as other serine proteases is given here.

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Ethanol injection was performed in the liver and VX2 carcinoma in rabbits and we evaluated changes with time by MR imaging, including dynamic study, and pathological findings. Many peripheral diseases are associated with a decline in cognitive function. Metabolic secretagogues that stimulate insulin secretion by the activation of initial steps in the glucose-stimulated insulin secretion pathway can also lead to increased reactive species production and cellular destruction contributing to beta-cell damage and apoptosis.

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Practice nurses need special training to extend knowledge and skills well beyond those of general professional training in order to function competently, with assurance, and with safety. Studies on human subjects establish the clinical significance of these devices for rapid and non-invasive characterization of skin mechanical properties. The most common clinical findings were rectal bleeding and constipation. Effect of hepatocyte proliferation and neoplastic transformation on alpha-fetoprotein (AFP) and albumin (ALB) production per cell.

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In this study three T cell lymphomas that differ markedly in their susceptibility to NK-mediated lysis from normal mice are shown to bear quantitatively but not qualitatively different degrees of NK target structures. Large bore drainages did not prove to be more effective in controlling the septic focus. Despite a high variability in clinical presentation, CPEO/KSS patients typically show an intramural pattern of LGE in the basal inferolateral wall whereas MELAS patients are characterized by overt concentric hypertrophy and a rather unique, focally accentuated and diffusely distributed LGE. Pulmonary arteriography confirmed the diagnosis of left pulmonary thromboembolism (PTE). Oligoclonal IgG bands in Japanese patients with multiple sclerosis.

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When DC were implanted 4-6 d after the induction of inflammation in mice a significant depression of DC granulopoiesis was observed. There was also a significant interaction between the manual restraint and behavioral conditioning interventions. Many centers have attempted to reduce the cost of dialysis by using dialyzers on multiple occasions after cleaning and sterilization.

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The addition of reducing agents to mashes increased the soluble protein, free amino nitrogen (FAN), and extract values of their resultant worts, and this effect was abolished by the concomitant addition of oxidizing agents. Peripheral blood stem cell transplant for POEMS syndrome is associated with high rates of engraftment syndrome.

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The present study indicates that the prevalences of NMSC and SK in Japanese have increased during the last three decades and that skin type I may be a risk factor for NMSC in Japanese. In the next step, these optimal reservoir storage values are considered as constraints for water storage in the annual reservoir operation optimization models.

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Comparison of the delayed actions of growth hormone and somatomedin on adipose tissue metabolism. Metabolic suppression before storage at 4 degrees C contributes to better preservation of PLT function.

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Stimulation was observed with concentrations ranging 0.4 to 50 micrograms/ml and was dose-dependent within the concentrations up to 10 micrograms/ml during 24 h treatment under conditions in which procollagen synthesis was increased. Stigma also presented a barrier to successful community and vocational re-integration.

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These data extend previous findings that point mutation of codon 61 may be an improbable yet possible event leading to activation of c-Ki-ras-2 in colorectal carcinoma. The economic consequences are obviously great, both for the individual patient and for society.

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We indicate that it is reasonable to consider ADD as a distinct entity, frequently co-occurring with LD on the one hand, and COD on the other. As the blood circulated through a thin transparent medical tube, it was exposed to light of 660 nm wavelength generated by an LED array.

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Our studies indicate that hematocrit and protein synthesis are not dominant mechanisms of acute adaptation to hypoxia. Recent studies indicate that mechanisms serving to elevate arterial pressure in the elderly diametrically differ from those in younger patients with similar elevation of arterial pressure. The aim of this study was to evaluate the association of self-reported leisure-time preoperative physical activity with postoperative recovery and complications after elective cholecystectomy due to gallstone disease.

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When SO4 was substituted for Cl, secretion rate also fell, but in association with a fall in net PD. The mean placental volume was lower in the investigated group but with not statistical gnificance. We present a rare case of intrinsic ureteral endometriosis resulting in a life-threatening infection and loss of a kidney. To that end, we went on to examine the participation of mitogen-activated protein kinases (MAPKs) in substance P-induced synthesis of pro-inflammatory chemokines, monocyte chemoanractant protein-1 (MCP-I), macrophage inflammatory protein-lalpha (MIP-lalpha) and macrophage inflammatory protein-2 (MIP-2), in pancreatic acini.

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In each MSD, the internal reporting of NI relies on the discovery of multi-resistant bacteria, but above all on the implication of those involved in the fight against nosocomial infections. This study translated a comprehensive health literacy questionnaire into Japanese and confirmed its reliability and validity. IL-18 is a unique cytokine with prominently wide spectrum biological actions. Localization and physiologic role of neuropeptides and their receptors--peptides of the bombesin family--GRP, neuromedin B and neuromedin C Thus, validating in this context that upregulation of E2F2 represents a key intermediate event in a HER2 oncogene-directed gene expression-based signaling circuit.

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Acidic fibroblast growth factor modulates gene expression in the rat thyroid in vivo. A case is described in which an anomalous insertion of the flexor pollicis longus tendon into the region of the carpal tunnel caused limited active flexion of the thumb in a child. Studies of natural killer cell activity and antibody-dependent cell-mediated cytotoxicity among patients with acute leukemia in complete remission.

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The retina cell columns are each formed of six peripheral cells plus two central cells, a partially fused rhabdom, and dense pigment in two or three cell types. A decrease in all enzymes and the GSH level could explain an increase in the susceptibility of the brain capillary ECs to further oxidant injury. Research in surgery: comparison of British and American practice.

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For RI to have therapeutic significance however, this normalization would have to be stabilized. The zetaz value is in direct proportion to the acceleration of healing, and in inverse proportion to the initial ulcer area. A simple solution, very inexpensive, is outlined and includes a 3-finger pinch of salt, a 3-finger pinch of sodium bicarbonate, and 2 teaspoons of potassium chloride dissolved in 100 cu. Graft-versus-host disease after autologous bone marrow transplantation: a realistic expectation?

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Quantitative gene expressions of peroxysome-proliferator-activated receptors (PPARs), glucose transporter 4, insulin receptor, IGF-1, leptin and interleukin-6 (IL-6) in skeletal muscle, adipose tissue and liver were also measured at both stages. After several rounds of screening, 18 primer pairs flanking di-, tri-, or tetranucleotide repeats were identified that revealed high levels of genetic diversity in two native Italian populations, with two to 11 alleles per locus.

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Synthetic human beta-endorphin increased plasma glucose concentration when administered intracisternally in chronically cannulated, conscious, unrestrained, adult male rats. Inhibitory Interneurons That Express GFP in the PrP-GFP Mouse Spinal Cord Are Morphologically Heterogeneous, Innervated by Several Classes of Primary Afferent and Include Lamina I Projection Neurons among Their Postsynaptic Targets.

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The findings of the brain wave during hyperthermic cancer therapy On the submicroscopic level, the activity of ATP-ase has been revealed on the internal side of the cytoplasmic membrane. Patients judged the SMiLE as reflecting well their MiL, not distressing to fill in and were moderately positive with regard to its helpfulness. Leukemia-derived transforming growth factor was heterogeneous on heparin affinity chromatography, fractionating into three peaks of activity.

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The use of synthetic absorbable monofilament suture material (polydioxanone, PDS), is described for operative vascular surgery. 3-D computational modeling of media flow through scaffolds in a perfusion bioreactor. This morbidity must now be assessed in relation to the benefits of avoiding temporary fecal diversion in restorative proctocolectomy. The serine/threonine kinase LKB1 is a tumor suppressor whose loss is associated with increased metastatic potential.

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Dimethyl sulfoxide in experimental atherosclerosis of the rabbit. RNA synthesis in the polymorphonuclear leukocytes of a suppurative wound Obtained results indicate that the new hydrogel can be suitable for sustained drug release formulations. Somatostatin inhibits and reverses hypergastrinemia induced by parathyroid hormone, calcium, and acetylcholine. The therapeutic and prophylactic value of magnesium needs further assessment.

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Binding was rapid and was not readily reversible upon adding unlabeled factor XII. The final patient with atypical pain had no improvement after the procedure.

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Antibodies to alcohol altered liver cell determinants in patients with alcoholic liver disease. A sensitivity analysis was done to examine the robustness of the conclusions.

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General acetylating capacity of the body of patients with rosacea Since protective cartilage surface proteins break down readily after the induction of acute arthritis in experimental animals, and in rheumatoid cartilage specimens, it is postulated that proteolytic degradation of the surface proteoglycans may be responsible for increasing cell adhesion to, and subsequent pannus invasion of, articular cartilage in inflammatory arthritis.

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To examine the association of insulin-related biomarkers including insulin-like growth factor-1 (IGF-1), insulin-like growth factor binding protein-3 (IGFBP-3) and C-peptide with CRC risk and assess their relevance in predictive models. Circulating levels of sex steroid hormones and risk of endometrial cancer in postmenopausal women. Epstein-Barr virus-specific T-cell recognition of B-cell transformants expressing different EBNA 2 antigens.

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Puberty acceleration by a urinary cue from male mice in feral populations. Enhanced oral bioavailability of insulin-loaded solid lipid nanoparticles: pharmacokinetic bioavailability of insulin-loaded solid lipid nanoparticles in diabetic rats. Estradiol and progesterone receptor levels were measured in endometrial samples obtained from patients who were on different dosages of estradiol therapy and from women in the late proliferative phase of a normal menstrual cycle.

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However, they are often difficult to read and to interpret, and can bring about more confusion than illumination to an audience. Thus, they seem to recognize neuroectoderm associated differentiation antigens. Sprague-Dawley rats were divided into two groups, a control group and an alcohol group. DNA sequence of the lymphotropic variant of minute virus of mice, MVM(i), and comparison with the DNA sequence of the fibrotropic prototype strain.

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Problems associated with the evaluation of nursing students undertaking the basic nursing course in Queensland. This study explores the possibility that the delayed hypoperfusion observed after an ischemic insult might be due to vasoconstriction induced by the release of noradrenaline from nerves originating in the locus ceruleus. In Experiment 4, female rats were administered estrogen (20 microg/kg) and amphetamine (1.0 mg/kg) for 3 weeks and tested for paced mating behavior 1 and 4 weeks later, amphetamine free. Pseudo-cluster-like headache secondary to contralateral epidermoid cyst of the pontocerebellar angle. Chronobiologic dynamics of delta 5-3 beta-hydroxysteroids and glucocorticoids in rat brain and plasma and human plasma.

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Detection of acute myocardial ischemia by serial ECG analysis of ST and VG vectors has equal or even superior performance than the STEMI criteria. Although no retinal break was demonstrated, several clinical features suggested that the detachment was rhegmatogenous. The possible relationship between RHG, accompanied by the described immunodeficiency, and the FHN is described.

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Work Status and Return to the Workforce after Coronary Artery Bypass Grafting and/or Heart Valve Surgery: A One-Year-Follow Up Study. Although considerable evidence has indicated that various xenobiotics may be immunosuppressive, little attention has been directed toward ascertaining a specific cellular locus which could be responsible for the impaired immune responsiveness. In recent years afferent nerves have started to be identified and are found in greatest numbers around the main salivary ducts, where they may form a hypolemmal association with the epithelial cells. In the present study, pesticide-treated cultures were found to synthesize reduced levels of interferon. Clinical and serologic constellations and their therapeutical implications are discussed.

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The proposed model is compared with reprogramming of differentiation of some cell lines by cytidine analogs and with ontogenic systems of differentiation control. Suppression could occur under conditions of both developing and pre-established delayed hypersensitivity. Evaluation of a monoclonal antibody (TB72) based serological test for tuberculosis. Evaluation of response to immunotherapy: new challenges and opportunities for PET imaging.

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Amicrobial crystalline deposits were more frequent and calcified bacteria were more uncommon. Trauma of various origins can induce a connective tissue disorder that leads to keloids. Superoxol and aminopeptidase tests for identification of pathogenic Neisseria species and Moraxella (Branhamella) catarrhalis.

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Sputum culture results were obtained if available as part of normal patient care. Even after allogeneic transplantation leukemia recurred after 5 to 19 days. Asphyxia was evidenced by severe neonatal systemic acidosis as documented by a venous cord pH of less than 7.0 whenever available, or acidosis in subsequent arterial blood gas samples, and clinical signs of an acute hypoxic-ischemic encephalopathy during the neonatal period. We conclude that Ab responses to GD3 are independent of NKT cells and that strategies to manipulate NKT cells in vivo are not likely to enhance the anti-GD3 Ab response induced by vaccines.