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The bioassay provides an accurate and sensitive method for measuring antiplatelet activity without the need for extraction of plasma samples and may be used to measure activity in any solution which is compatible with PRP. Treatment of choice is complete surgical resection of the lesion. Atrial remodeling exhibited a high interindividual variability but no relationship within different remodeling levels, with AF duration or with LA hemodynamic load. Cerebral RFA is a relatively safe and effective technique capable of producing a predictable ablation with no damage to surrounding brain. We have shown that despite the high structural homology of the subtilisins and the SPCs, the structure of the loop which lies immediately below the active sites differs due to the presence of a cis-peptide bond (Tyr167-Pro168) in this loop in the subtilisins and its absence in the SPCs.

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A 45 cm diameter polyvinyl balloon attached to plastic tubing was used for rectal distention following a stepwise barostat-controlled inflation pattern. Immunogenic properties of endotoxins of Yersinia enterocolitica serotypes according to the Knapp and Thal antigenic classification Administration of propranolol directly into the anterior descending branch of the left coronary artery (LAD) resulted in a localized increase in myocardial contractile force in the area of the left ventricle perfused by the LAD. Inappropriate placement of a patient with childhood hypomania in a mental handicap hospital for 51 years.

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The non-ionic compound of 3-mercapto-2-hydroxypropyl ether of dextran with cupric sulphide was obtained. Opinions on the traumatizing effects of child sexual abuse: evidence for consensus.

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Differential diagnosis should be made with the portal-hypertension pattern of congenital liver fibrosis and, according to the clinical manifestations, with liver cirrhosis. Recent studies using chemical assays of released amino acids, high-affinity uptake mechanisms of Glu/Asp from nerve terminals, the direct micro-iontophoretic administration of Glu/Asp antagonists, and immunocytochemical techniques have demonstrated that almost all corticofugal efferent projections employ Glu/Asp as excitatory synaptic transmitters. Imaging of osteonecrosis is frequently diagnostic with a serpentine rim of sclerosis on radiographs, photopenia in early disease at bone scintigraphy, and maintained yellow marrow at MR imaging with a serpentine rim of high signal intensity (double-line sign) on images obtained with long repetition time sequences. This study provides basic data for researches of cell senescence and cytopathic effect and is helpful to diagnosis and prevention of diseases.

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They can be constructed either as in situ sensors or as flow-through sensors connected to the process via sampling devices. The Gordon Wilson Lecture: The new cell biology and its implications for medicine. The duplex is distorted on both sides of the cross-link, but the bases are still paired.

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Pharmacologic considerations in the management of oral surgery patients in general dental practice. This suggests that defective function in the T lymphocyte and/or macrophage population rather than in the B cell population may underlie the defect in IgM production. Gene markers identified in a private laboratory of the city of Puebla, Mexico. NukM, the modifying enzyme of nukacin ISK-1, which is produced by Staphylococcus warneri ISK-1, catalyzes the dehydration of specific Ser/Thr residues in a precursor peptide, followed by conjugative addition of intramolecular Cys to dehydrated residues to generate a cyclic structure. In fission yeast Schizosaccharomyces pombe, the nuclear envelope remains intact throughout mitosis and undergoes a series of symmetrical morphological changes when the spindle pole bodies (SPBs), embedded in the nuclear envelope, are pushed apart by elongating spindle microtubules.

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Treatment results by using the Rehrmann plastic procedure, as well as complications and sequelae are described. Gender differences in nitric oxide production by alveolar macrophages in ethanol plus lipopolysaccharide-treated rats. Bilateral lesion of the amygdala complex and the hippocampus brings about a decrease of the heart rate under the action of emotiogenic stimuli instead of its increase, and diminishes the difference between objective manifestations of positive and negative emotional states. Prognostic significance of sex in childhood B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group Study.

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Widely accepted is the initiation of a conservative treatment regimen for undisplaced fractures, however, the standard treatment for displaced fractures, especially three and four part fractures, is still the center of scientific debate. Gas-phase plume from laser-irradiated fiberglass-reinforced polymers via imaging fourier transform spectroscopy.

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The Ministry of Health and Welfare and the reorganization of the programs of environmental health in Mexico Chronic acid-related disorders are common in primary care, and many patients use acid suppressing medications on a long-term basis. Everyday ethics in assisted living facilitites: a framework for assessing resident-focused issues. The temporal and frequency characteristics of this model are consistent with experimental data on peripheral auditory system.

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To investigate whether myopia is becoming more common across Europe and explore whether increasing education levels, an important environmental risk factor for myopia, might explain any temporal trend. Characterization and interactions of a fragment of the core protein of the small proteoglycan (PGII) from bovine tendon.

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The contributions of these field procedures to patient outcomes should be evaluated further. in Bacillus subtilis DB104 for the production of xylobiose from xylan. Owing to this central role in governing mitogenic signals, RAS pathway components are often dysregulated in human diseases. This data acquisition system performs signal handling on a shot-by-shot basis at the 1 kHz repetition rate of the pulsed laser system. In this report we extend our genetic analysis of the MAL loci to a number of maltose fermenting and nonfermenting natural strains of S.

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The results of the study showed no changes in any of the measured clotting factors during anaphylactic shock. Reduction in serotonin 5HT2 receptor binding on platelets of delinquent adolescents. The type of immune response generated is dependent upon the nature of the immune stimulation. Multiple case reports describe haemorrhage resulting from primary or metastatic lesions affecting different organs.

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The 10 patients given slow-release melatonin reported significantly better scores on the Pittsburgh Sleep Quality Index than the nine patients given placebo. Short-term evaluation of the patient operated on for aorto-coronary bypass by the exertion test The platelet starts out as a fine granular structure that rather suddenly changes in form and function with the passage of a very small amount of time. The balance between negligence and overconcern is therefore very difficult to make, and requires experienced physicians. A9 L cells stable transfected with m1 muscarinic receptors were stimulated with the full agonist carbachol and with the partial agonist pilocarpine.

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This results in transient stromal edema immediately anterior to the injured endothelial cells. An estimation of mechanical stress on alveolar walls during repetitive alveolar reopening and closure. Anti HIV-1 sera showed neutralizing activity against heterologous and even autologous escape virus.

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However, because OI is quite rare, this possible diagnosis may be overlooked in situations where the child seems to have clearly suffered non-accidental trauma. Pre-and postoperative hyperextension and hyperflexion radiograms were observed to measure range of motion (ROM) of C2-7, operative and adjacent levels. Data were extracted using a narrative synthesis, and quality was assessed using the Critical Appraisal Skills Programme.

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The proposed methodology was evaluated in an aerobic lab-scale system operating with COD removal and nitrification. The blood alcohol concentration obtained was 1.88 mmoles/liter and splanchnic uptake of ethanol was calculated to be 1.18 mmoles/min. We conclude that the TJs of odontoblasts may play an important role in the differentiation of odontoblasts in rat lower incisors during early dentinogenesis. Diagnosis in dentistry and dental x-rays--dental x-ray photographs--a discussion The Nuclear Regulatory Commission regulations for the release of patients administered radioactive material have been revised to include dose-based or activity-based criteria.

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Sex discriminatory effectiveness using combinations of permanent teeth. However, Tvpgp1 is half the size of typical P-glycoproteins which are tandem duplications. Inhibitory activity of midaglizole (10(-4) M) for the alpha agonists was BHT-920 greater than noradrenaline greater than or equal to phenylephrine, while that of prazosin (3 x 10(-6) M) was phenylephrine greater than noradrenaline greater than BHT-920. Manifestations of craniometaphyseal dysplasia in otorhinolaryngology

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At the end, the procedure for error analysis is given by testing homebuilt optical tweezers. Pretranslational upregulation of microsomal CYP4A in rat liver by intake of a high-sucrose, lipid-devoid diet containing orotic acid. The effect of 6 weeks dietary lipid manipulation on the acute physiologic response to 7-hour continuous endotoxin infusion in guinea pigs was examined. Characteristics of epidemiology and clinical course of pulmonary tuberculosis in inhabitants of Northern Russia

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The results suggested that gossypol acetate, danazol and progesterone might have peripheral effects mediated by steroid receptors, while GnRH-A work clinically through the central path way only. Activation of extracellular signaling regulated kinase in natural killer cells and monocytes following IL-2 stimulation in vitro and in patients undergoing IL-2 immunotherapy: analysis via dual parameter flow-cytometric assay.

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Ectopic calcifications and even bone formation have been linked to GNAS gene mutations. We have explored in COS-7 cells the mechanism of ERKs activation by m1 and m2 muscarinic receptors, typical examples of receptors coupled through Gq proteins to induce phosphatidylinositol hydrolysis and to G(i) proteins to inhibit adenylyl cyclase, respectively. The results showed that the mean numbers of observed and expected alleles in peripheral populations were higher than in central populations. Beta-carotene enhances the recovery of lymphocytes from oxidative DNA damage. Atraumatic technique for atrial synchronous and atrioventricular sequential pacemakers.

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Effect of isolation induced aggression in mice on serum creatine kinase. Conditions and motivations for the desire to have children in young females Comparative properties of various beta-blockers, with an outlook to the future. A comparison of the effects of intravenous tramadol, codeine, and morphine on gastric emptying in human volunteers. Application to the etiology of nausea reported during chemotherapy, concerns about significance testing, and opportunities in clinical trials.

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Many patients with proteinuric chronic nephropathies progress relentlessly to end-stage renal failure (ESRF). The incidence of prostate cancer has surged dramatically in recent years due to improved cancer screening and detection mechanisms.

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The number of agranular vesicles per square micrometer of synaptic surface, as well as the number of agranular vesicles per synapse, were found to be greater in the rat than in the pigeon, while no significant differences were found in coated and dense core vesicles. This defect in this patient indicates the importance of the tyrosine No.

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Campylobacter fetus subspecies fetus cellulitis associated with bacteremia in debilitated hosts. We were unable to demonstrate the coexistence of pairs of substances in any neurones in the leech ganglia. These results are consistent with mediation of nitrogen-induced trehalase activation by the free catalytic subunits alone.

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Treatment targets should include subclinical cognitive-motor impairment and neuroprotection, as well as MCMD and HAD. Death, graft function, proteinuria and adverse events were systematically analysed during the study period. Interestingly, one CIS was the transgene itself, where retrovirus integrations induced upregulation of p210BCR/ABL and production of truncated BCR/ABL with an enhanced kinase activity. This effort was made possible by the fortuitous presence of the three scientists necessary for such an operation, to wit, the forensic pathologist, a forensic odontologist, and a forensic anthropologist.

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Liquid-chromatographic separation and on-line bioluminescence detection of creatine kinase isoenzymes. Based on our results in patients with germ cell testicular tumors we assume that the poor clinical outcome seen in certain Pgp positive tumors is the consequence of Pgp association with a more progressive malignant phenotype, rather than its role in multidrug resistance (MDR). Distance trees were constructed that support the hypothesis of monophyly of the genera Vespula and Dolichovespula. To investigate the therapeutic efficacy of uterine artery embolization in the treatment of uterine fibroids and to analyse the influential factors to the therapeutic efficacy.

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The avulsed central was reimplanted and the other one derotated and stabilised with orthodontic wire and brackets. Although many geriatric patients with schizophrenia have been referred to nursing home care, little is known about their characteristics.

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Also in the combination of cataract and glaucoma operations the triangular scleral flap was found to be useful. Plasma zinc as a predictor of diarrheal and respiratory morbidity in children in an urban slum setting. However, transcription of closed circular DNA is stimulated when negative supercoils are introduced by the addition of DNA topoisomerase II and supercoiling factor purified from the posterior silk gland of Bombyx mori. These findings suggest that, for the mouse, intrarenal biotransformation of APAP to a reactive electrophile significantly contributes to the APAP covalent binding within the kidneys and the subsequent nephrotoxicity.

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Overall, OUT-reared pigs presented lower n-6/n-3 FA ratios, whereas pigs fed the HO diet exhibited lower saturated fatty acids (SFA), higher monounsaturated fatty acids (MUFA) levels and lower thrombogenic indexes on neutral intramuscular lipids than LO-fed pigs. Exertion-related disorders in body temperature regulation in 8 participants in the Dam-to-Dam run 1993

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The unique specificities and spatial relationships of these antibodies were determined by variant analysis, haemagglutination inhibition (HI), neutralization, passive mouse protection, and antibody blocking assays. In conclusion, methoxamine at the dose of 0.025 mg/kg has a greater effect on peripheral resistance vessels than on Winkessel vessels in the rat systemic circulation. The bactericidal activity of two newer quinolones, ciprofloxacin and ofloxacin, against eight strains of Salmonella typhi was examined by the serum dilution test and studies of bacterial killing kinetics in human serum, and compared to standard regimens. An unusual transposition of the maxillary central and lateral incisors.

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Reproducible percepts were more easily generated than those that matched the stimulation pattern. Replating of HL-60 cells growing in the presence of 1.0 mM thymidine in liquid medium in thymidine-free soft agar produced significant colony inhibition, also suggesting that thymidine affects more than just deoxyribonucleotide synthesis or that the clonogenic HL-60 cell presents a distinct subpopulation with more sensitive deoxyribonucleotide-synthetic control mechanisms. The finding of hematopoietic PP14 within the megakaryocytic lineage provides an additional regulatory link between the coagulation and immune systems in normal and pathological settings.

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Liver transplantation in case of acetaminophen poisoning: importance of assessment of the colon if arterial lactate increases despite appropriate care. This statement was recently challenged by another understanding that protein tethering on material surfaces instead of matrix stiffness was the essential cue to regulate stem cells. Desk-top analysis of the structural stability of various point mutations introduced into ribonuclease H. On the other hand, no induction of increased IRP1 binding to IRE was observed in rodent cells exposed to formaldehyde. Reduction in recharge, as conventionally assumed due to the impact of urbanization, could not, however, be well established.

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Photocatalytic degradation of organic dyes with manganese-doped ZnO nanoparticles. In layers V and VI they mainly contact with the dendrite trunks and with the nervous cell bodies and more rarely with thorns. Maxillary sinus revision--clinical, radiographic and endoscopic findings It appears therefore that FGFR-2 expression in fibroblasts and EC cells is regulated by somewhat different mechanisms. Relations of the 25 mammalian selenoprotein genes with obesity and the associated inflammation remain unclear.