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PGL-1 marginally increased the IP3 levels in BT/TT patients, whereas in BL/LL patients, it had no effect. The extensive destruction of CNS tissue in the transitional region of the trigeminal root where CNS and the peripheral nervous system meet is discussed with reference to the pathogenesis of HSV encephalitis. Two types of cellular IL-1Rs have been characterized and cloned from both human and murine sources.

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The groups could be clearly differentiated both at the behavioral and electrophysiological level. CT could detect more bone destruction of the skull base than the conventional submental view. Offline surface registration was performed to quantify interfraction and intrafraction setup errors, and the required planning target volume (PTV) margins were calculated.

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For amine/Au and thiol/Au junctions, a crossover in conductivity with increasing bias is predicted. Improved efficiency of treadmill exercise testing using a multiple lead ECG system and basic hemodynamic exercise response. Null functions and eigenfunctions: tools for the analysis of imaging systems. Species are well-discriminated using shape but the best discrimination occurs when species have either a long evolutionary history (e.g., Allenopithecus nigroviridis) or represent extremes of size variation (Miopithecus sp. This finding possibly bears out vasomotor hypothesis of migraine.

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Study of iron, iron-binding capacity of blood serum and proteinogram in children with rheumatism without anemia or with concomitant anemia Fresnel zone plates are used as pupil apertures to extend the depth of field of an incoherent imaging system. As the first obese gene product identified, leptin participates in many physiological processes. In these patients FSP was found in only two cases during the 2nd week, while in 12 untreated patients it was found in 10 cases. The mean age at testing was 14.3 months, with a range of 3-30 months.

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The 263 studies in this review were heterogeneous with regard to their methodologies and aims. Those with an adequate clinical response to initial treatment may be discharged on oral antibiotic therapy with appropriate follow-up. The comparison with the available experimental spectra confirms the results obtained with the DFT computations. Epidemiologic studies, rather than controlled human exposure studies, are required to determine whether ozone pollution increases the risk of asthma exacerbations.

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A single 5-minute test LAD occlusion did not protect against subsequent regional ischemic dysfunction in our subset of patients with normal baseline function. We studied nasal mucociliary transport using a radioisotopic technique and ciliary ultrastructure in 14 patients with KS. Recent studies indicate that choline is recycled in the liver and redistributed from kidney, lung, and intestine to liver and brain when choline supply is attenuated.

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Interaction between radiation and drug damage in mammalian cells. Brain glucose uptake, oxygen metabolism, and blood flow in humans were measured with positron emission tomography, and a resting-state molar ratio of oxygen to glucose consumption of 4.1:1 was obtained. Otolaryngologists are in the front line of physicians asked to evaluate children whose language development is lagging. Duplex PCR system for simultaneous detection of Neisseria gonorrhoeae and Chlamydia trachomatis in clinical specimens. Measurements of maximum expiratory flows and lung volumes were made on 6 occasions at weekly intervals in 14 children who were known over several years to have severe chronic asthma.

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No patient had surgical intervention or change in symptoms in the time interval between catheterization and MR imaging. Human leukemic myeloblasts shed glycoproteins from the cell surface during short-term in vitro culture. Reinnervation of denervated skeletal muscle by central nerve fibers regenerating along replanted ventral roots.

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Bone Marrow-Derived Mesenchymal Stem Cells Improve Diabetic Neuropathy by Direct Modulation of Both Angiogenesis and Myelination in Peripheral Nerves. A procedure has been developed to quantify the levels of aggrecan and link protein mRNAs in small amounts of various tissues, including cartilage, using the power of PCR to amplify extremely low levels of specific templates. Data extracted from these studies were synthesised using thematic synthesis.

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These novel findings, that CsA nephrotoxicity is associated with lipid peroxidation and that a chain-breaking antioxidant ameliorates whereas its deficiency exacerbates, indicate a role for lipid peroxidation, presumably free radical-mediated, in CsA toxicity. Two additional patients died at 23 and 28 months, respectively, after surgical removal of the lesions, and at autopsy, no evidence of recurrence was noted. Subsequent O2 loss from the TR leaves either an epoxide with a pi-delocalized electron or a pi-delocalized oxepine, by cleavage of the ring carbon-carbon bond. Neurologic lesions following chiropractic measurements of the spine While making decisions, subjects were required to signal detection of auditory probes.

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It is shown that the composite coating consists of OCP and protein with a highly ordered and hierarchically porous structure in nano-micro scale, similar to the naturalbone structure. Laboratory studies of Venezuelan equine encephalitis virus in equines, Texas, 1971.

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The capacity to selectively alter IL-1-induced gene expression suggests that this version of the IL-1Ra is a unique intracellular inhibitor that attenuates IL-1 responses at a point downstream of the initial IL-1/IL-1 receptor interaction. In the first group, administration of autologous bone marrow MNC and vascular endothelial growth factor (VEGF) plasmid was performed. In CHO cells, tiazofurin is more toxic than ribavirin and also demonstrates a stronger inhibition of guanine nucleotide synthesis. Conjunctival dermoid cyst seen on examination as a chronically red eye.

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In women the relationship between myotonic dystrophy type I and fertility remains controversial. Integrated CTA scores are able to identify individual patterns of higher risk. Powdered, sterilized zinc polycarboxylate was implanted subcutaneously in 56 young hamsters and 54 mice, using equal numbers of each sex, with 24 sham operated hamsters and 26 mice as controls. A modified geometric factor approach to internal gamma ray dosimetry.

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Rising labor costs, earnings management, and financial performance of health care providers around the world. Therapeutic monoclonal antibodies and consistent ends: terminal heterogeneity, detection, and impact on quality. Antiarrhythmic and hemodynamic effects of an aminosteroid (Org 3001) in the digitalized dog. parva ( Muguga ) were also capable of neutralizing the infectivity of sporozoites of other strains.

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Cyclin-D1 has been strongly implicated in cell cycle proliferation particularly in the G1/S checkpoint in the cell cycle, and prognosis in many human malignancies. Proceedings: Lithocholate kinetics in patients ingesting chenodeoxycholic (chenic) acid for gall stone dissolution. There is an age dependence with a maximum of the ratio total cholesterol/HDL cholesterol in the age group 61-70 years. Total ropivacaine plasma concentration remained below toxic concentrations and no adverse effects occurred. Chi-square tests were used to examine the potential associations among the independent variables.

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The ETR1 gene product has an amino-terminal hydrophobic domain and a carboxyl-terminal domain showing homology to the two-component signal transduction proteins of bacteria. This amine, released on the mucosal surface, was observed in only very small concentrations in the circulation. These experiments suggest that the post-obstructed, poorly functioning kidney stimulates contralateral hyperplastic growth and increased renal function. When included into a thrombin-induced fibrin polymerization reaction, rFnbA strongly inhibited fibrin assembly in a dose-dependent manner. Work reported in this issue of Biochemical Journal (Haqq et al.) demonstrates that the cytosolic tail of an attractin-like protein (ALP) binds directly and specifically to the C-terminal region of MC4R, raising the possibility that proteins of the attractin family influence melanocortin receptor function through multiple mechanisms.

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Variation across categories of race, sex, and body mass in the atherosclerosis risk in communities study. Intravenous injection of PACAP-38 and PACAP-27 resulted in a dose-related increase in plasma PRL levels both in conscious rats and in urethane-anesthetized rats. The influence of ornidium (bretylan) and papaverine on the biopotential and electrolytes metabolism in the vascular wall was studied in tests with cats. Furthermore, our model permits the dissection of species-specific factors in the microenvironment. The chosen floral traits were under selection by hummingbird and hawkmoth pollinators, with hawkmoth abundance highly variable across years.

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Self-healing of coronary aneurysm after implantation of paclitaxel eluting stent:a case report Moreover, the ability of several family members (death receptors) to induce death (mainly via apoptosis) represents a promising target for cancer therapy. By ELISA we observed a significant increase of MCP-1 in the testicular fluid (TF) and in the conditioned medium obtained from cultures of testicular macrophages of rats with EAO compared with control groups.

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To compare the antihypertensive effect, and tolerability and safety of once daily doses of KT3-671 with that of placebo in patients with mild to moderate uncomplicated essential hypertension. Analysis of the delta F508 mutation in a Brazilian cystic fibrosis population: comparison of pulmonary status of homozygotes with other patients.

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IgG antibodies, eluted from kidneys of rats with Heymann nephritis were separated into cationic and anionic fractions, labeled with 125I and 131I, respectively, mixed in equal amounts, and then injected in incremental doses into 10 rats. The axons of these CSF-contacting neurons were followed into the magnocellular portion of the paraventricular nucleus.

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Guidelines for dental treatment planning are outlined, and extraction versus conservation of teeth is discussed. No significant differences were observed in anthropometric data between PWS patients with the 15q chromosome deletion and those with normal chromosomes. Appearance of homogeneous smectic multilamellar microenvironments in biomembranes undergoing superoxide-initiated lipid peroxidation: lipid-dienyl radical accumulation and fluidity management in lipid bilayers. The mouse splenocyte assay, an in vivo/in vitro system for biological monitoring: studies with X-rays, fission neutrons and bleomycin. Proteasome inhibitor (bortezomib) and immunomodulatory drugs (thalidomide and lenalidomide) now play important roles in the treatment of MM, and they have resulted in an improvement of the outcome of the patients.

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Visceral leishmaniasis although not frequent now a days, the incidence of PKDL is still prevalent to some extent in this country. He developed serious side-effect such as renal dysfunction, when conventional amphotericin B was given. Exposure to 900 MHz EMF during the prenatal period can cause pathological and biochemical changes that may compromise the development of the male rat thymus and spleen. In addition there are two other labelled fields in this region whose nature (fibers v.

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Comprehensive evaluation of electronic medical record system use and user satisfaction at five low-resource setting hospitals in ethiopia. The interaction regions were further defined by studies with synthetic peptides of hhG alpha h and a chimera in which residues Val665-Lys672 of hhG alpha h were substituted with Ile707-Ser714 residues of human coagulation factor XIIIa.

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Using 6 novel DNA methylation data sets, we show that HIV infection leads to an increase in epigenetic age both in brain tissue (7.4 years) and blood (5.2 years). These findings might offer hope for the development of new targeted therapies, specific to tumor cells, which spare healthy cells.

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In vitro lymphocyte reactivity to rubella antigen following vaccination. The gamma2 subunit of GABA(A) receptor is specifically required for clustering of these receptors, for recruitment of the submembrane scaffold protein gephyrin to postsynaptic sites, and for postsynaptic function of GABAergic inhibitory synapses. On the second and third day of postirradiation syndrome the behavioural inhibition was observed. Animals in a third group (D-amphetamine-injected) were weighed and administered D-amphetamine (0.5 mg/kg in saline) immediately before being placed in the chamber. The preclinical evidence for efficacy of pharmacological approaches that target epigenetics in the CNS and the particular challenges of this approach are also examined.

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Significant others, knowledge, and belief on smoking as factors associated with tobacco use in italian adolescents. To determine if a wide genital hiatus is a risk factor for recurrence of anterior vaginal wall prolapse following anterior vaginal repair. In adoptively transferred EAE, in vitro activation of myelin basic protein (MBP)-specific lymph node cells was inhibited by the combination of anti-CD80 plus anti-CD86, but not individually. The aim of this study was to investigate the feasibility of an in situ hybridization technique for detection of HTLV-I mRNA in atypical lymphoid cells of peripheral blood and skin lesions of patients with ATLL. A total of 3292 employees aged 34 years and older were selected from the entire employee population of 6543 in a Japanese corporation.

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Characterization of chemical species in atmospheric aerosols in a metropolitan basin. These results indicate that other factors besides collagen synthesis may enhance the oxidation of AA in the early stage of tissue regeneration. Electrocardiographically, signs of myocardial infarction can be missed in ALCAPA, other forms of dilative cardiomyopathy (DCMP) often showing similar clinical features.

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A procedure is described for the detection of an in vitro proliferative response to the autologous mouse myelin basic protein in mice injected with mouse spinal cord homogenate (MSCH) or with myelin basic proteins (BP) of mouse (MBP) or rat (RBP) origin. S-layer proteins are one of the most abundant biopolymers on earth.

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The superagonist nafarelin acetate, D-Nal(2)6-GnRH, was administered intranasally in one daily dose of 125 micrograms to 25 women and 250 micrograms to 22 women. X-ray-induced production of granulocyte-macrophage colony-stimulating factor (GM-CSF) by mouse spleen cells in culture. Population pharmacokinetic modelling of the enterohepatic recirculation of diclofenac and rofecoxib in rats. Cryosections of retinal tissue at different developmental stages and cultured retinal cells (either not permeabilized or permeabilized with acetone) were incubated with a rabbit antiserum that specifically reacts with the retinal 16-kd S-lac lectin.

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Electromyographic (EMG) activity of masseter and anterior temporal muscles, and bite force were analyzed in 28 young, fully dentate women with painful and tender masseter muscles before and after intramuscular injection of either lidocaine or saline in superficial masseter muscle. If further studies replicate this finding, policies to improve parenting could be expected to have a modest beneficial impact on health as well as emotional and social development. The purpose of this study was to evaluate the advantages and drawbacks of semirigid fixation compared with rigid fixation using an external fixation system.

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In group III, the involvement is milder, ranging from the sonographic findings typical of group II to those of normal-appearing urinary tract. carpocapsae but in the temperature of 25 degrees C the activity of H. Repair of a strip perforation with calcium-enriched mixture cement: a case report. The enzyme reaction was developed for visualization by transmission electron microscopy.

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Comorbidity between depression and asthma via immune-inflammatory pathways: a meta-analysis. How to prevent the spreading of respiratory syncytial virus in pediatric departments?

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Stapedius reflex latency, rise, and amplitude were more sensitive to the presence of a tumor than were measures of threshold and decay. In hippocampus, SST expression and release is regulated by seizures, and SST-containing neurons within the hilus of the dentate gyrus are sensitive to seizure-induced death. In the interest of stimulating new thoughts and experiments in this area, a number of preliminary findings have been freely cited. Experiences with this formulary are discussed and recommendations for improvement are made. The youth of these patients and lack of other predisposing factors suggests that heroin played a role in their strokes.

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Genetic diagnosis of Charcot-Marie-Tooth disease in a population by next-generation sequencing. DNA viruses undertake their replication within the cell nucleus, and therefore they must first deliver their genome into the nucleus of their host cells. Low-dosage dobutamine magnetic resonance imaging as an alternative to echocardiography in the detection of viable myocardium after acute infarction.

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Although oncogenically activated ras alleles are common in some types of human cancers, the frequency in human carcinoma of the prostate (CaP) has not previously been addressed. Timely diagnosis and intervention are imperative, and, therefore, we recommend the early use of arteriography using digital subtraction angiographic techniques for the definitive diagnosis.

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Cat eye movements were recorded during wakefulness and paradoxical sleep with the technique of the scleral search coil in a magnetic field. Harper and Cawston characterized the active substance, Harper-Cawston factor (HCF), and later studies indicated it to be a protein. Mean ICP, mean pulse pressure amplitude and B-like wave amplitude increased significantly during transient sleep and REM sleep.