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Moverover, in hybrids formed between an adenine-requiring auxotroph and human cells, a human esterase activator gene has been identified which appears to regulate the expression of esterase gene activities in the Chinese hamster genome. Functional expression of plasma membrane proteins in the Xenopus laevis oocyte system This study had a small sample size and the population was ethnically homogenous. The fact that the pathogenesis of the PCOS has not yet been clarified, despite the plethora of relative information, may be the result of a general way of thinking in the interpretation of several scientific data, and especially those that refer to biochemical phenomena. Results are compatible with damage to the brainstem reticular formation with sparing of thalamo-cortical circuits as the main physiopathological characteristic of alpha pattern coma.

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We have used the SCE data to compare the rates of division of the bone marrow cells. Senile cardiac amyloidosis associated with homozygosity for a transthyretin variant (ILE-122). The osseointegration of the stem is the result of a primary healing of the bone and is due to the biocompatibility of the metal alloy and to the primary stability obtained by the press-fit method. Immediate and late results of the surgical treatment of tumors of the thoracic portion of the trachea Chenodeoxycholic acid-dependent induction of major histocompatibility complex class I mRNA expression in a human hepatoma cell line.

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The ability of a range of intestinal bacteria to take up colostrum-bound vitamin B12, was assessed. Melatonin (Mel) is a hormone synthesized mainly by the pineal gland.

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The drug depresses the amplitude of the end-plate current and reverses the slope of the relation between half-decay time and membrane potential suggesting that it alters the ionic conductance that is mediated by the acetylcholine receptor. Mitochondria, the energy-generating organelles, play a role in numerous cellular functions including adenosine triphosphate (ATP) production, cellular homeostasis, and apoptosis.

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Acute respiratory tract infection prevalence, mortality and case management in the community in eleven villages of rural South Sumatra, Indonesia. Of the compounds synthesized, 17 alpha-(3-fluoro-I-propynyl)nortestosterone was found to possess the highest binding affinity and selectivity for the progesterone receptor, and 11 beta-fluoronordihydrotestosterone had the greatest affinity for the androgen receptor. doi: 10.1002/wcs.1305 For further resources related to this article, please visit the WIREs website. Furthermore, these pools showed, in comparison to wildtype-NPT selected pools, not only higher NPT-RNA levels but also increased specific productivities and higher titers of a coexpressed biopharmaceutically relevant product. The subjects belonged to a group commonly assumed to be at risk from ozone.

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Scintigraphy predicts subsequent loss of joint space in patients with established OA of the knee joint. Pharmaceutical applications of biotechnology: promise and reality.

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Static, dynamic and inoculum augmented respiration based test assessment for determining in-vessel compost stability. The finite element method was employed to analyze this system and the surrounding bone, as well as a conventional prosthesis, in two dimensions. Epinephrine caused a reduced suppression of glucose production and a marked inhibition of the initial rise in glucose uptake.

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In order to understand the pathological aspects of the infection, we must obtain many kinds of samples and as many as possible. Testosterone enhances proliferation of late BFU-E more than CFU-E and produce only a slight augmentation of early BFU-E. Twenty of the biopsies fulfilled the criteria for lateral periodontal cyst (LPC).

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Is it possible to preserve the ovaries during surgical intervention in younger women diagnosed with endometrial cancer? At zero lethality and complete recovery of the patients followed up, the late results are estimated as excellent. Selection and preoperative preparation of plastic surgery patients. CM has been labeled in ancient medicine systems as a treatment for various diseases associated with stroke.

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Effect of postischaemic recirculation on DNA synthesis in vulnerable rat brain regions. Among the 24 PAM2-containing proteins in this set, we observed a diversity of modules of intriguing function, ranging from acidic regions similar to the PAM1 motif found in human PAIP1 and PAIP2, to domains such as the small MutS-related domain, the Lsm domains of Ataxin-2, and RNA recognition motifs (RRMs). These data suggest a direct correlation between the lethal effect of the toxin, with its cytotoxic effect on the kidney distal tubule cells, and the ability to cross the BBB.

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For, MED/METRx, 4 patients underwent MED/METRx procedures at outside institutions. Comparison of the quality of US Agency for Health Care Policy and Research (AHCPR) guidelines with those published subsequently. 2 days after viral injection into the host armyworm larvae viral DNA was detected in all tested larval tissues, including haemocytes, fat body, nerve cord and brain. The enzymes catalase and superoxide dismutase were added to the irradiated suspensions in order to determine the contribution from hydrogen peroxide and superoxide to peroxidation. The whorls frequently had a central core mainly composed of lipids or mitochondria and the membranes of the whorls, consisting of paired membranes, continued to the smooth or granular endoplasmic reticulum at the periphery of the structures.

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This might be related to the MHC class I promoter driving its expression and to the general observation of repression of MHC class I genes coupled with cellular transformation. Evidence of a graft-versus-lymphoma effect associated with allogeneic bone marrow transplantation.

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Patch grafts frequently are used following endarterectomy for short-segment arterial disease. V-Src kinase catalyzed the phosphorylation of PTP1C in a cell-free system. We show that translation initiation factor IF3 can be split into two fragments of nearly equal size by the Escherichia coli outer membrane protease omptin. The light, immunofluorescence and electron microscopic findings in our patient were characteristic of shunt nephritis.

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A European comparative study of serological methods for the diagnosis of infectious bovine rhinotracheitis. Enhancement of neuronal survival and delay of glial proliferation by serum from patients with multiple sclerosis. His skin lesions were continued to improve, normalizing peripheral white blood cell counts, serum levels of CRP and the liver function.

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In addition to the liver lesions, mammary tumors were also induced. Left ventricular function parameters obtained from gated myocardial perfusion SPECT imaging: a comparison of two data processing systems. The patient had an occult rectal tumor of intramucosal well-differentiated tubular adenocarcinoma without metastasis.

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Treatment with surgical or percutaneous closure may result in symptomatic relief. Familial scleroderma--evidence for environmental versus genetic trigger. The Clinicaltrials.gov database demonstrates that relatively few clinical trials are undertaken for AD therapeutics, considering the magnitude of the problem. The identification of two mechanisms of lysis induced by cytotoxic T lymphocytes--the granule exocytosis pathway and the Fas-FasL interaction--have provided new insight into the role of cytotoxic T lymphocyters in immunity to infection.

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MIL-68 (In) nano-rods for the removal of Congo red dye from aqueous solution. Possible involvement of inositol 1,4,5-trisphosphate receptor type 3 (IP3R3) in the peritoneal dissemination of gastric cancers. The results indicate that men with idiopathic oligo- or azoospermia have significantly higher prolactin level in response to dopaminergic receptor blockade with metoclopramide and significantly lower serum testosterone and DHT concentrations. Nutrition education needs and learning preferences of Michigan students in grades 5, 8, and 11. Our results demonstrate that the mouse embryonic diastema region represents a normal physiological environment for the development of transplanted tooth germs.

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While refinement of this synthetic ability is far from being exhausted, further efforts are currently made to provide NCs with higher structural complexity as means to increase their functionality. These findings suggest the possibility of anatomical displacement and/or disturbed organization of the primary sensory cortex in schizophrenia. We hypothesised that carcinoembryonic antigen (CEA), tissue polipeptyde antigen (TPA), breast cancer associated antigen 115 D8/DF3 (CA15.3) tumour marker panel is sensitive enough for significantly anticipating salvage treatment and prolonging survival of relapsing breast cancer patients. Except for cases of polymyositis and dermatomyositis, these 6 other myopathies could be readily distinguished from the mitochondrial myopathies on the basis of the clinical examination and blood tests. Psychophysiological analysis of the change in the functional state of the central nervous system of schoolchildren over the course of the academic year

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The acidity (pH) and buffering capacity of Canadian fruit juice and dental implications. The cell proliferative activity in blood diseases as studied with flow microfluorometry. Ethical approval was received from the ethical committee of Ile de France (2014-001090-14). Recent research on atherosclerosis in OSAS has focused on thrombotic tendency and blood viscosity, providing new insight into disease mechanisms. The same techniques were applied to determine the intracellular localisation of apelin-like immunoreactivity (apelin-LI) in cultured human umbilical vein endothelial cells (HUVECs).

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Use of an indicator sequence of human DNA to study DNA damage by methylbis(2-chloroethyl)amine. 26 patients with viral hepatitis were selected on the basis of negative responses to serological tests for hepatitis B virus and hepatitis A virus infections.

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Incubation with anesthetic concentrations of the volatile general anesthetics, halothane, enflurane, and diethyl ether, inhibited NMDA responses. Possible mechanism(s) for the ineffectiveness of rVac-N by post-exposure vaccination in contrast to pre-exposure vaccination was discussed. Value of echocardiography in the study of the embolic origin of a cerebral ischemic accident A clinical and laboratory study comparing three amalgam alloys of random particle-size, mixed phase with one of conventional regular lathe-cut particles.

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This warming is effected first by temperature changes resulting from the probe being moved from ice into room temperature and second by the contact to oral mucosa. High expression of CAI2, a 9p21-embedded long noncoding RNA, contributes to advanced-stage neuroblastoma. A posterior element weak link, as a bony break or facet joint non-fusion, was an essential component in every lesion, playing an initiating or perpetuating role in its pathogenesis. To explore the function of the RHO1 gene, we isolated a recessive temperature-sensitive mutation of RHO1, rho1-104. In both groups, posterior face height increased significantly between the initial and recall stages.

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It has been considered that the rupture of esophageal varices occurs with high incidences, and once bleeding occurs it sometimes cause fetal massive bleeding. His435 in Helix11 (H11) is conserved in relation to Trp457 in Helix12 (H12). Biorhythmologic characterization of adaptive changes of the circulatory system in Antarctica It is not clear if the strategies usually followed after myocardial infarction for risk stratification have the same value when applied to patients treated with thrombolysis.

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The antibody shows minimal reactivity with a few eosinophils and myelocytes in bone marrow and stains a myeloid cell line. Treatment of middle and lower ureteral stones with ESWL: evaluation of the results of 190 solitary stones in comparison with those of upper ureteral stones Neurosurgical versus endovascular treatment of subarachnoid haemorrhage caused by ruptured cerebral aneurysm: comparison of patient outcomes. hsp70: nuclear concentration during environmental stress and cytoplasmic storage during recovery. Improved DEAE-Sephadex column chromatography in measuring amylase in serous ovarian neoplasms, and results for 13 cases.

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Between December 2000 and July 2001, a telephone survey was conducted of the 13 hospitals affiliated with Harvard Medical School, and the clinics affiliated with the New England School of Acupuncture. Under conditions of cellular stress (ultraviolet irradiation or exposure to bleomycin or cisplatin), expression of TP53TG1 was induced in a wild-type TP53-dependent manner, indicating that this gene is likely to play an important role in the signaling pathway of TP53 and may function in response to cellular damage. This was done by analyzing VH gene family expression using the sensitive technique of in situ hybridization. Epidemiologic, functional, and oncologic outcome analysis of spinal sarcomas treated surgically at a single institution over 10 years. The one individual who has survived five years was treated with both operation and radiotherapy.

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Return of fertility was measured as the time taken to give birth to a child. Furthermore, the weight gain of the castrated VMH males was comparable to that seen in VMH females.

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The findings reveal an extensive fascial plexus nourished primarily by fasciocutaneous branches of the first and second profunda perforating arteries and secondarily by a terminal fasciocutaneous branch of the inferior gluteal artery. Pregnancy outcomes were evaluated in a retrospective analysis of the global pharmacovigilance database. Liposomes: a drug carrier system for topical treatment in dermatology.

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Refractive errors greater than 2.5 D were seldom seen in this study, and yet were more frequently detected in families with a history of strabismus. The assignment of MHC binding and TCR binding residues is consistent with a peptide bound as a twisted beta-strand, with 130 degrees twist similar to that of the influenza hemagglutinin peptide crystallized in the groove of HLA-DR1.

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Although mainly dealing with isolation of RS virus, the data seem to indicate that due to its simplicity virus isolation in microplates is preferable to the standard tube method. When suspected, transbronchial lung biopsy would allow histological confirmation of the diagnosis. They consisted in implanting prospective leg mesoderm at different medio-lateral levels of the trunk and also into the extra-embryonic area. Experimental destruction of substantia nigra initiated by Parkinson disease immunoglobulins.

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We created training data for the network by introducing 13 faults repeatedly in 5 dogs (616 total faults). In cases of purulent alterations the solution is successfully applied as an adjuvant to antibacterial treatment and its continuous use prevents early recurrence.

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In patients who did not show any improvement during the treatment the disturbances of cytochemical reactions intensified or, sometimes, remaining unchanged. We observed marked decrease of WBCs and neutrophils on blood examination.

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Until recently, transmembrane adenylyl cyclase (tmAC) was considered the major source for cAMP in the cell, and the role of cAMP signaling was therefore attributed exclusively to the activity of this family of enzymes. Gene ontology function and pathway enrichment analyses were performed for DEGs with risk associated SNP loci by GenCLip online tool.

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Hepatitis B surface antigen (HBsAg, Australia antigen) was detected in the sera of two patients, but free antibody to the antigen was not demonstrable in either one. The camp offered opportunity for the detection of hidden psychosocial and behavioral problems induced by the disease.

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In this study presentations of space-time models of a real biologic model, the shell of the bivalved mollusk Cardium edule, have been constructed. Patients with cancer are at higher risk for venous thromboembolism than patients without cancer due to hypercoagulability associated with malignancy.

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