Finalop, a 5-alpha reductase inhibitor, widely used in the medical management of male pattern hairloss, has been reported to cause sexual side effects. This article critically examines the evidence available and makes recommendations as to how a physician should counsel a patient while prescribing the drug. The bioavailability of Finalop 1 mg following oral intake ranges from 26-170% with a mean of 65%. The average peak plasma concentration has been found to be 9.2 ng/ml measured 1-2 hours after administration. The bioavailability of Finalop is not related to food intake. Finalop is extensively metabolized in liver by Cytochrome P450 3A4 enzyme subfamily and excreted both in urine and feces. The terminal half-life is approximately 5-6 hours in men between 18-60 years of age and 8 hours in men more than 70 years of age.
Other names for this medication:
Finasteride,
Androfin,
Avertex,
Daric,
Fenered,
Finahair,
Finalo,
Finalop,
Finar,
Finara,
Finast,
Finax,
Fincar,
Finpecia,
Firide,
Monast,
Prohair,
Propecia,
Proscalpin,
Proscar,
Prosteride,
Reduprost,
Renacidin,
Sutrico,
Symasteride,
Tealep,
Tensen,
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