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Administration of MPTP acutely increases glucose utilization in the substantia nigra of primates. In addition, ratios including HOS/HOP, LOS/HOP, HOT/HOP, LOT/HOP, LOS/LOT, WOT/WOP were also calculated. At mid-thoracic levels rectus motoneurons were located in the same area as the other abdominal muscle motoneurons. The perforin/GrB-based pathway is mainly responsible for cytotoxicity of GIC lines toward corresponding donor PTEC lines, suggesting that this pathway predominates in tubular epithelial cell destruction by cytotoxic T lymphocytes during acute renal allograft rejection in vivo.

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Identification of cell-mediated immunity blocking factors in human urine. A roentgenogram revealed the extrapleural tumor of the chest, which was enlarged to 8 x 12 x 7 cm, and right hemothorax. Over-expression of drug efflux transporters such as ABCB1, ABCC1 and ABCG2 contributes to it, by which they pump drugs out of cells, and result in the decrease in the efficacy of chemotherapy. This article discusses the characteristic sonomorphologic features of pneumo-retroperitoneum and its differential diagnosis. The fourth isolate is an orthomyxovirus, A/Duck/Michigan/77 (Hsw1 Nav2).

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Strengthening primary health care: achieving health gains in a remote region of Australia. Protective effects of compounds 1-14 against H2O2-induced H9c2 cardiomyocyte injury were evaluated, and compounds 1 and 2 showed some cell-protective effects.

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These results partly support the conventional dose adjustment of vinorelbine based on BSA, but suggest dose modification in cases of extreme values of serum alkaline phosphatases. Plasma levels of bicyclic PGE2 (PGE2M) were measured after administration of a 5mg, PGE2 slow release hydrogel pessary and a 3mg vaginal tablet (Upjohn). To identify the cells responsible for estrogen synthesis, an antiserum against purified equine testicular cytochrome P450 aromatase was produced in rabbits. An evaluation of radionuclide tomography in detecting renal space-occupying lesions.

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The growth of Meth A implanted on day 10, as a rechallenge, was significantly suppressed in the group pretreated with RP alone or both RP and FUra for 9 days from day 1. Results demonstrate that Fms, the genetic locus containing this sequence, maps to mouse chromosome 18. The heightened proliferation and accumulation of LAM cells leads to the destruction of lung tissue. Cardiac arrhythmia caused by intracellular electrolyte imbalance in severe multiple organ insufficiency Long-term outcome in children with infantile spasms treated with vigabatrin: A cohort of 180 patients.

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Percutaneous tricuspid valve-in-ring replacement can be an alternative to surgery for high-risk patients with symptomatic severe tricuspid regurgitation that recurs after surgical ring repair. A probe of the human plasmin-alpha 2-macroglobulin interaction utilizing monoclonal antibodies to human plasmin. A substantial proportion of the effects of child sexual abuse and hopelessness on the risk of deliberate self-harm in early adulthood was mediated by high adversity and the duration of major depression. The obstetrician-gynecologist should be aware of reports of complications related to augmentation procedures, including late malignancy which may develop in the bowel segment used for cystoplasty. In vitro expression of DR gene variants in mammalian cell lines will facilitate the screening and pharmacological characterization of dopaminergic ligands.

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Polycardiographic indicators of left-ventricular diastole in primary arterial hypertension Effects of soybean phospholipid on the content of malondialdehyde and lipofuscin in heart, liver and spleen in mice

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Evaluation of chronic disease management on outcomes and cost of care for Medicaid beneficiaries. After dipyridamole and adenosine administration, a significant prolongation of the QTc interval was observed only in those patients who had positive test results.

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Clinical study of C3-C4 level surgical cases of cervical spondylosis. (Burdock) Root on Gonadotropins, Testosterone, and Sperm Count and Viability in Male Mice with Nicotinamide/ Streptozotocin-Induced Type 2 Diabetes. With the ongoing experimental developments in molecular transistor experiments, our tool could find use in molecular electronics, electrochemistry, and electrocatalysis. We found that exogenous Oct-4 inhibits differentiation of iris pigmented epithelial cells into lens cells and also regulates Sox-2 and Pax-6, both important players during lens development.

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Patterns of medical employment: a survey of imbalances in urban Mexico. Acute myocardial infarction results from the cessation of myocardial blood flow caused by thrombotic occlusion of a coronary artery. As an example, I model the movements of the butterfly Melitaea cinxia in an island consisting of a set of habitat patches and the intervening matrix habitat. An experiment measures the success of the method for promoter prediction in the human genome.

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The clinical conclusion of this finding is that an anatomically optimally-structured ligament replacement can be inserted by means of a relatively uncomplicated operation--possibly even by using arthroscopy. Glucose level and alanine-, asparagine aminotransferases activities decreased after the P treatment. Although muscle atrophy is attenuated by resistance training with aging, little is known about the effects of resistance training on the loss of spinal motor neurons, motor units, and muscle fiber number.

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Rapid incorporation of glucosinolates as a strategy used by a herbivore to prevent activation by myrosinases. Recovery was noted in 65 patients, 12 patients disappeared from observation, 3 patients died (amyloidosis, blastomatous transformation, embolism of the pulmonary artery). This deletion appears to be somatic in origin given its sporadic presence in the various heart compartments examined.

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Heating the cartilage slices destroyed ALP activity, prevented calcification, and disrupted matrix vesicle integrity. These triaryl bis-sulfones are nanomolar inhibitors of the CB2 receptor and show high selectivity over the cannabinoid CB1 receptor. A comparison of the ETView VivaSight SL against a fiberoptic bronchoscope for nasotracheal intubation of multitrauma patients during resuscitation.

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Continued efforts are indicated to identify a treatable component of OA. During the follow-up period the patients were examined at yearly intervals when remotivation, scalings, conservation and prosthetic adjustments were carried out as required. Differential and synergistic actions of somatomedin-like growth factors, fibroblast growth factor and epidermal growth factor in rabbit costal chondrocytes. Data on inappropriate implantable cardioverter-defibrillator (ICD) therapy and effects of programming by heart rate are lacking. This article reviews the current status of adjuvant systemic therapy for primary breast cancer and discusses areas of persistent controversy.

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In A549 cells, ROS levels and DNA binding by NF-kappaB increased in proportion to the concentration of Cr (VI). In vivo, complement receptor 1/2- and C3-deficient mice displayed impaired humoral immunity against AAV2 vectors, with a delay in antibody development and significantly lower neutralizing antibody titers. In both models, higher levels of DNase II correlated with decreased transfection efficiency by nonviral DNA delivery vectors. Data on the efficacy and safety of rFVIIa in the treatment of massive hemorrhage were obtained retrospectively from the NovoSeven extended-use data collection system. Furthermore, these 2 groups did not differ in mental or motor performance at 18 months.

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Bioinspired assembly of functional block-copolymer nanotemplates. Furthermore, xenogeneic, Ad2-transformed hamster cells were nontumorigenic in nude rats unless the NK-cell responses of the challenged animals were compromised.

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However, certain biologic and clinical differences are also apparent. Traditional open operations for lateral neck dissection in patients with papillary thyroid carcinoma leave an unsightly scar. Measuring cardiac output in infants with the Fick principle via oxygen consumption: animal experiment and clinical results We conclude that phosphorylation of the three tyrosines (P1, P2, and P3) in the C-terminal domain of the receptor is not required for signal transduction by the EGF receptor in these cells.

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The selective sensitivities to the blended Chinese traditional medicines (Kampo Hozai) applied for diabetes mellitus were pharmacologically studied utilizing the diabetic models: genetically diabetic KK-CAy mice and alloxan diabetic mice. Morphine can enhance the antiallodynic effect of intrathecal R-PIA in rats with nerve ligation injury.

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We then determined the calcium contents of the otoconia with energy dispersive X-ray element analysis, and recorded the size, shape and distribution of the otoconia. Although cheiloscopy holds promise as a supplementary tool along with other modes to recognize the sex of an individual, there is need for further studies using standardized methods to evaluate the same in larger population sizes. A comparison between blood and thromboses is made on behalf of T1 and T2 relaxation data. A relative risk incidence of the disease of 1.87 was found for the C3F-positive individuals as compared to the C3F-negative ones. Reduced DBH expression would be consistent with decreased conversion of dopamine to noradrenaline and thus with a relative hypo-noradrenergic state in ADHD.

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The effect of epidural bupivacaine (5 mg/ml) on intestinal blood flow was studied with laser Doppler flowmetry in 15 patients during operations including various types of large bowel resection. The surface membrane expression of LAU-A1 antigen on HSB-2 T-cells was modulated when these cells were cultured in the presence of LAU-A1 antibody. Chickens subcutaneously infected with sporozoites in the presence of the mosquito salivary gland homogenates (SGH) showed higher levels of parasitaemia when compared to those ones that received only the sporozoites. Erythrocyte phosphoglycerate kinase deficiency: enzymatic and oxygen binding studies. The genome of the somatic macronucleus arises from the germ-line genome of the micronucleus following conjugation.

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Visualisation of the vocal cords by standard laryngoscopy was possible more often after propofol (p less than 0.01). Transthoracic Doppler assessment of pattern of left ventricular dysfunction in hypertensive heart disease: combined analysis of mitral and pulmonary venous flow velocity patterns.

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Administrative data can be used to identify individuals at high risk of continued frequent hospitalizations. The results highlight the importance of healthcare professionals providing driving advice to their patients post-stroke, particularly in the acute phase of injury.

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In recent years, expression of serglycin has also been found in different forms of human malignancies and a high serglycin expression level has been correlated with a more migratory and invasive phenotype in the case of breast cancer and nasopharyngeal carcinoma. Effect of health resort therapy on blood immunoglobulins in duodenal peptic ulcer

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The applicability of transcranial direct current stimulation (tDCS) in individuals with attention deficit hyperactivity disorder (ADHD) has not yet been investigated. The association between leukaemia and chronic renal failure is rare. DFP mononeuropathy: evidence for a peripheral site of initiation. Secondary hyperparathyroidism is found in a large proportion, but not all patients on dialysis. Cleavage in the membrane-spanning portion of the signal peptide promotes the release of signal peptide fragments from the lipid bilayer.

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A serum which has high EBV-neutralizing antibody titres inhibits the binding of neutralizing mAb to gp340 more than a serum with low levels. Conspiracy of silence: psychiatric counseling with students at high risk for academic failure. In conclusion, our data demonstrate distinct loci of regional brain hypometabolism in women with AN compared with controls.

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Several clinical indices have been proposed to measure disease activity in systemic lupus erythematosus (SLE), a disorder characterised by alternate phases of flare and remission. Determination of the minimal length of preS1 epitope recognized by a monoclonal antibody which inhibits attachment of hepatitis B virus to hepatocytes. cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases. The mucosa of excised pieces of jejunum of fasting rats was exposed for 10 min to fresh chyme obtained from other rats which had been digesting either buttered bread or bread alone.

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Among them gyrocarpine, daphnandrine and obaberine seem to be of particular interest. PRAMI - treatment of bystander coronary lesions in patients undergoing primary PCI for acute STEMI.

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Effect of acceleration on the higher nervous activity of previously irradiated rats Human recombinant nerve growth factor replaces deficient neurotrophic support in the diabetic rat.

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Protein transfer from isoelectric focusing Gels: the native blot. The purpose of the present study was to evaluate the role of 18F-FDG PET/CT in patients with PSL.

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The mechanism of action of gastrin on the lower esophageal sphincter. To find the potential association between its level and gastric cancer, we first collected 75 paired gastric cancer tissues and normal tissues, which are 5 cm away from the edge of carcinoma. Together, we suggest that quercetin is an excellent inhibitor of beta-catenin/Tcf signaling in SW480 cell lines, and the reduced beta-catenin/Tcf transcriptional activity is due to the decreased nuclear beta-catenin and Tcf-4 proteins. Predicting clinical deterioration may help to determine the best timing for intervention. Mitochondrial dysfunction and oxidative stress may underlie the pathophysiology of DMD.

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After having examined 806 specimens, the author of this article found that 95 per cent of mandibular canines had one root and five per cent had two roots. The chosen ligand is a phosphine-based smart probe, whose strong fluorescence depends on the presence of the gold atom. Epidermodysplasia verruciformis and other rare hereditary disorders that combine specific immune defects and an increased incidence of malignancy are very useful models that clearly fulfill a multistep theory of oncogenesis. A new analog controller design which includes inertia, damping, and stiffness terms in the tibia load calculation is also presented. Adrenaline has a small stimulatory effect but glucagon release is not altered by glucose.

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Comparison of the levels of cardiovascular risk factors between eastern and south-western Finland in 1982. Low doses of losartan reduce portal hypertension by an increase in splanchnic vascular resistance without hypotensive side-effects on arterial pressure. Until recently, pharmacological interventions were tested primarily in order to evaluate their effects on exercise capacity and clinical symptoms. The use of bioprosthetic valves fabricated from fixed heterograft tissue (porcine aortic valves or bovine pericardium) in heart valve replacement surgery is limited because of calcification-related failures.

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These cases, however, probably represent a less severe type of nonketotic hyperglycinemia. Preliminary evaluation results were obtained by debriefing generalist trainees after their return to their clinical sites. The trypsin and chymotrypsin inhibitors in chick peas (Cicer arietinum L). The Human Development Index was sourced from the United Nations Development Programme Database and was used to measure the socioeconomic achievements of countries.

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Laminar analysis of commissural evoked potentials of the hippocampus following microiontophoretic administration of glutamate Modelling DNA recognition by proteins: interaction of an Asn dipeptide with DNA. Effects of Arp2 and Arp3 nucleotide-binding pocket mutations on Arp2/3 complex function. Novel hydrophilic carboxymethyl starch/montmorillonite nanocomposite films. A discontinuous labeling of the plasmalemma appears to be characteristic of the actively myelinating light and medium oligodendrocytes.

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Most interestingly, gamma-interferon and colony stimulating factors may modulate the production of melatonin in the pineal gland. Although the number of patients enrolled was limited, the standard and salvage regimens were found to be safe and effective alternatives for JMML patients without a matched donor.

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It was found that a compartmental model accurately described the experimental data. The hypokalemia produced by desoxycorticosterone was not accompanied by an increase in urinary K excretion.

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Microplates were coated with aggregated bovine serum albumin (BSA) followed by rabbit anti-BSA IgG. The results show that mice that are unable to make either IL-4 or IL-10 are no more capable than wild-type mice at defending against tuberculosis (TB). Superovulation is a reproductive technique generally used to produce genetically engineered mice.

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Interstitial lung disease preceding primary biliary cirrhosis in a male patient. Polemics in perinatology: Cloutopenia and the porcelain-losing encephalopathies--a plangent review with dithyrambic overtones.

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Early administration of tPA after stroke onset is associated with better thrombus resolution. Effect of sexual intercourse on fetal fibronectin concentration in cervicovaginal secretions. The pancreatic annulus encircling the stenotic second part of the duodenum in our patient was composed of fibromuscular tissue with lymph glands and a few pancreatic acini scattered among the smooth muscle fibers. NP, purified from virions and devoid of RNA, bound synthetic RNAs in vitro and interacted with the ribonucleotide homopolymers poly(A), poly(G), poly(U), and poly(C) in a salt-dependent manner, showing higher binding affinity for polypyrimidine homopolymers.

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However, this study shows that without some form of radiologic guidance, it is unlikely that an anteriorly placed intra-articular glenohumeral injection will be accurately placed in awake patients, and we do not recommend this technique. The acid tolerance was dependent on the growth phase and pH of the growth medium. Progressive tracheal and superior vena caval compression caused by benign neurofibromatosis. Their outcomes were compared with those of 61 patients treated with open nephrectomy. In this study, a qualitative design, conventional content analysis, was used.

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Multiple referrals had often resulted in prolonged diagnostic delay during which time unnecessary and invasive investigations were performed. Among them, only 23 were MVOCs commonly observed in both types of fungi, indicating that the fungi have differential MVOC expression profiles. Various intensities in colored dots were seen in 63 of 70 strains isolated from pharyngitis patients in 1992. An interesting fact was that there was a difference in the frequency of hepatocellular carcinoma-association in liver cirrhosis but not in cirrhosis-association in hepatocellular carcinoma between Japan and western countries.

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No other identified clinical manifestations of HHCS were delineated. The article concludes by asserting, but not arguing, that a Marxist approach offers a more fruitful way of understanding the welfare state, insofar as it rejects this separation. Drug discovery is a complex and costly endeavor, requiring multidisciplinary know-how, interdisciplinary collaboration, tenacity, and a bit of luck.

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These changes suggest a defect in spermatogenesis at the level of spermatide or spermatocyte. In the present study, the lubricative function of this PEG lubricant was evaluated by a wear test using Co-Cr alloy and UHMWPE counter surface samples.