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From these and other data it is concluded that there is no clear relationship between the capacity of the agents to induce tumour necrosis and their capacity to elicit TNF, cytostatic factors, and interferon. These results suggest that the pro-apoptotic action of selenium compounds is mediated by both thiol oxidation and the generation of O(2) .-), both of which contribute to opening of the MPT pore. The P1 vector system for the preparation and screening of genomic libraries. Homoloyg search and limited proteolytic digestion showed that the enzyme has a C-terminal 58-kDa catalytic domain very similar to that of human lysosomal beta-hexosaminidase that is responsible for hydrolyzing gangliosides. Pharmacologic sensitivity of the photopic c wave in the electroretinogram of the chicken.

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To the best of our knowledge, this is the first reported case of primary pulmonary plasmacytoma presenting with lobar consolidation of the lung but without a well-defined tumor mass. Significantly improved tumor/nontumor ratios were found when the SA was given between 24 and 48 h after the PA in comparison to 6 h.

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A study was made of the effect of cycloheximide on the radioresistant DNA synthesis stimulated by preincubation of cells with 5-fluorodeoxyuridine (FdUrd). At low levels (less than 1 microM) of CsA, however, sensitisation to colchicine was greater in the parent line than in cell line CR 2.0.

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Pili of Mycobacterium tuberculosis: current knowledge and future prospects. Effect of thyroid status on basal phosphorylation of cardiac myofibrillar phosphoproteins in rats. One of the more common cervical lesions seen in children is cervical lymphadenitis. The biochemical abnormalities are discussed in relation to previous biochemical data from MHS humans and pigs and in relation to the abolition of dietary-induced thermogenesis.

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Inhibition of cleavage of Moloney murine leukemia virus gag and env coded precursor polyproteins by cerulenin. The procedure is based on the photometric determination of the inactivation of thrombin after incubation with plasma in the presence of endogenous antithrombin III (At III). We believe that this method (abscess drainage with mediastinoscope and wash-out repeatedly) is useful for those who has broncheal fistula after esophagectomy.

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The prognosis depended on the species rather than the number of organisms isolated and on aggressive antimicrobial and surgical therapy. Laboratory diagnosis of Clostridium difficile-associated diarrhoea: a plea for culture.

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Data-prompted interviews: Using individual ecological data to stimulate narratives and explore meanings. Expression of VHb in transformants was demonstrated by Western immunoblot analysis and by increased carbon monoxide binding activity of cell extracts. Several segmental arteries arise from each uterine artery to the corpus uteri also side-specifically.

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The synaptic terminals as well as the preterminal swelling are occasionally linked by small synaptic junctions. Their demographic, clinical, radiological, and surgical features were documented. Altered activation pathways in T lymphocytes infiltrating human solid tumors. With an indirect agglutination technique using rabbit antisera to human immunoglobulin, IgG antibodies to rabbit erythrocytes were detected in 211 of 221 unconcentrated cerebrospinal fluids from patients with diseases of the nervous system and controls. A half-life of 17 days characterized the time course of positive scans according to their density and abnormal radioisotopic uptake area.

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Neonatal herpes simplex type 2 encephalitis: its appearances on ultrasound and CT. Acute variations of the plasma transferrin levels could be involved in the regulation of the GH secretion by a feedback mechanism. Lack of prognostic significance of T-cell receptor delta gene rearrangements in childhood B-precursor acute lymphoblastic leukaemia.

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The external region of the median eminence of the homozygous Brattleboro rat contains neurophysin-oxytocin fibres. Combined treatment of UFT with cisplatin (CDDP) achieved remarkable elongation of survival time of BDF1 mice, which were intravenously transplanted with Lewis lung carcinoma (LLC). Immunological data and one-dimensional peptide maps of the separated subunits suggest that a common (Mr 240,000) and a variant (Mr 220,000, 235,000, or 260,000) subunit account for the three different heterodimers. Chromogranin A (CGA), urinary 5 hydroxy indole acetic acid (U-5HIAA) and Neurokinin A (NKA) are used as laboratory diagnostic tests but results may be misleading or confusing. Its latency was short (between 1 and 20 s for both types of chemoreceptors.

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Consistent with animal models of SCI, spinothalamic tract lesion together with neuronal hyperexcitability due to lesion of inhibitory interneurons at the rostral end of injury are hypothesized to lead to central pain. It is most clearly expressed if both donors and recipients are immunologically crippled by thymectomy and irradiation.

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The recent development of transgenic mice expressing specific photolyases has identified cyclobutane pyrimidine dimers as the major player in ultraviolet-induced damage, including skin cancer. Basophils were observed in morphologic preparations and their granules stained most intensely for acid mucosubstance with the dialyzed iron method. Late mandibular angle fracture after operative removal of third molars MCPDD, although rare, should be included in the list of the differential diagnosis of periarticular calcific diseases.

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An acute myocardial infarction occurring in an anabolic steroid user. The effects of IL-7 on the expression of vascular endothelial growth factors (VEGFs) in MDA MB-231, MCF-7 and BT-483 cells were analysed by reverse transcriptase-polymerase chain reaction and western blotting. Reduction of tube current settings to 75-90 mA for thoracic, abdominal and pelvic examinations and to 90-130 mA for cranial examinations was not associated with any significant deterioration in image quality. Recycling of the general transcription factors during RNA polymerase II transcription.

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Arthritis caused by unidentified gram-positive rods in a child with acute lymphocytic leukemia. Combined assessment of left ventricular function and rest-redistribution regional myocardial thallium-201 activity for prognostic evaluation of patients with chronic coronary artery disease and left ventricular dysfunction.

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Discrimination between benign, borderline, and malignant epithelial ovarian tumors using tumor markers: an immunohistochemical study. Vestibular ototoxicity of gentamicin assessed by the recording of a short-latency vestibular-evoked response in cats.

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Here we demonstrate that the tilted mouse, like the head tilt (het) mouse, specifically lacks otoconia and consequently does not sense spatial orientation relative to the force of gravity. Aging in animals in accompanied by a decrease in exploratory drive, as assessed by hole poking and spontaneous alternation tests.

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A study of those patients seen by psychiatric consultants is reported. The toxicity of tirapazamine was determined using the MTT assay after either 96 or 3 h aerobic exposure or 3 h treatment in hypoxia. The physiological function of those which synapse at the vasopressin releasing area may be to act as a brake on vasopressin release, and of those which synapse at the more rostrally situated area to act as a brake on arterial blood pressure. The results suggested that different T cell factors are involved in the IgG and IgE antibody responses.

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Even though CAPD has several advantages over conventional dialysis as they are mainly founded on the high degree of rehabilitation of patients, risk of peritonitis is still a considerable factor of uncertainty. In view of this, investigations were carried out for establishing the role of adrenergic receptors in the development of motor function of this part of the intestinal tract. These results show that a mammalian DNA replication protein is also essential for repair.

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The model has been incorporated into an educational program for antenatal diagnosis within a residency and provides a reasonable simulation of clinical features important in learning genetic amniocentesis. A total of 80 male F344 rats were treated with 3 or 10 mg/kg of body weight JTE-522 or vehicle by oral gavage five times weekly from the start of the experiment.

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Clinical practice guidelines for the psychosocial care of adults with cancer. Plasmapheresis did not correct a concomitant suppressor T-cell defect, and the clinical remission ended during the fifth month of exchange therapy. Analysis of the network of residual contacts reveals the presence of a complex interface region between the two structural cores and indicates that the development of specific interactions within this interface is the key step in achieving the native structure. Coincidental with augmented NK cell activity, the LCMV-carrier mice rejected intravenously injected 125IUdR-labeled tumor cells more efficiently than did normal mice. Cell fractionation and electron microscope studies of kidney folate-binding protein.

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Problems of the management of residual cavities following resection When the length of the lever arm and the position of the mini implant are adjusted, the desired line of action of the distal force is determined with respect to the center of resistance of maxillary molars. Hydrological evidence suggested that the source of contamination was a dairy farm situated within the hydrological catchment of the polluted spring. Low energy expenditure, due either to physical inactivity or to metabolic factors, is also observed. Low-dose estriol used for urogenital discomfort is void of lipid effect.

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Method for rapid MRI quantification of global cerebral metabolic rate of oxygen. An 18-year-old boy was brought to the hospital with jaundice, confusion, abdominal discomfort and distension. As more retired racing Greyhounds enter the pet population, the results of this study will help educate veterinarians and owners about the most prevalent diseases in the breed. To our knowledge, this association has not been previously reported. Methylation-dependent binding of wheat nuclear proteins to the promoter region of ribosomal RNA genes.

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The DWR Department of Geriatric Medicine at OUHSC and the OKC VA Medical Center began a mandatory third-year geriatric medicine clerkship in 2003. PQQ adducts were isolated from guinea-pig neutrophils with each of the tritiated inhibitors. High frequency stimulation is known to induce long-term potentiation (LTP) and synaptic enhancement, however, the stability of these changes requires a bi-directional communication between the pre- and post-synaptic terminals and neurotrophins can function in such a capacity. Indirect dose-area product (DAP), fluoroscopy time (FT), and contrast medium volume were recorded. Two review authors independently extracted and synthesised data.

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Their intracranial pressures were monitored during periods of no treatment (the control), during the application of individual respiratory techniques and during a complete respiratory treatment. The NH2-terminal blocking group of the membrane-binding domain of NADH-cytochrome b5 reductase has been deduced as myristic (n-tetradecanoyl) acid. Eye tracking reveals a crucial role for facial motion in recognition of faces by infants.

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Isolation of Escherichia coli expressing 987P fimbrial antigen from suckling piglets. Patients aged 10 through 21 years were prospectively enrolled in this descriptive study. The results are compared with Monte Carlo calculations and were found to be in good agreement. The detection of CO changes in critically ill children might be missed by this error. Effect of polyethylene glycol 4000 on dissolution properties of sulfathiazole polymorphs.

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Spectra were calculated for successive, overlapping time epochs in seven channels. Correlation of peripheral blood monocyte and neutrophil direct counts with plasma inflammatory cytokines and TNF-alpha soluble receptors in the initial phase of acute pancreatitis.

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The problem of oncostatic specificity of cyclophosphamide (NSC-26271): Studies on reactions that control the alkylating and cytotoxic activity. This excluded the neuromuscular origin of the damage and confirmed the diagnosis.

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Numerical calculations of the transmission spectra of the 1DPhC FP resonant cavities using the Transfer Matrix Method (TMM), versus thickness of a biolayer simulating biomolecules (e.g. Two additional groups were immunized with K-BRSV or K-BRSV and CpG ODN.

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The plasmid bearing this repeat integrated in multicopy fashion, with up to 25 copies arranged in tandem. Hemolymph chemistry and histopathological changes in Pacific oysters (Crassostrea gigas) in response to low salinity stress. The histochemical study of the submaxillary and sublingual glands showed a very strong decrease in the polysaccharide and protein stainings in the 100 ppm group, whereas the 50 ppm group showed similar reactions to the control group. coli tryptophan-inhibited 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase.

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The inactivation by dopamine was negligible under the experimental conditions. To investigate the long-term radiographic course as a mathematical function of disease duration in individual patients and in a group of patients with rheumatoid arthritis (RA). In this regard, this unconstrained proliferation may represent primitive phenomena whereby cellular regulation is suspended or compromised. However, no correlation was found between prolactin and melatonin concentrations in any examined time points.

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In viral penetration, but not specific virus-cell binding, mutations of Y498 and Y487 plus Y498 substantially reduced the potential. A subsequent study will assess whether the Utstein factors explain differences in survival between emergency medical services (EMS) systems. Blood vascular invasion: a poor prognostic factor in adenocarcinoma of the prostate.

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The clinical picture was characterized by an insidious onset of altered behaviour, dementia, speech disturbance, myoclonus, and convulsions. In the present paper note is made of the low frequency of this disease in Mexico. Distortion of the helical superstructure of the doublets, most often by a reduction in helical pitch, is interpreted as revealing the development of tension between doublets. Monitoring vascular sclerosis in hypertension: a new window of opportunity.

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The femoral component of a surface-replacement total hip arthroplasty consists of a metallic cup affixed to a resurfaced femoral head with interposed methyl methacrylate. A total of 15 patients affected by idiopathic dystonia (7 with generalized and 8 with focal or segmental dystonia) were subjected to therapy with bromocriptine at low doses, pimozide and trihexyphenidyl. From the results of additional experiments in vitro, this transient decrease could be related neither to Ca-EDTA 2Na nor to lead in the blood. Spontaneous choledochal cyst rupture and consequent biliary peritonitis are rare in children. Isosorbide dinitrate (ISDN) and its two mononitrate metabolites were studied for their effects on the force-frequency relationship of isolated rabbit left atrial preparations.

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Cis-acting and trans-acting regulatory mutations define two types of promoters controlled by the qa-1F gene of Neurospora. Effect of bacitracin methylene disalicylate on turkey poult performance in the presence and absence of stunting syndrome. Prostate needle biopsy remains the gold standard for diagnosing prostate cancer.

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We hope that it will help to promote hospital-based HTA activities in France and discussions about ways to improve and harmonize practices, through the development of national guidelines and/or a French mini-HTA tool, for example. The fraction of metabolically active cells was drastically decreased by the intense hydrodynamic forces. It is increasingly clear that poly(3-hydroxybutyrate) (PHB) is not just an inert storage polymer, confined to certain bacteria, but a ubiquitous, interactive, solvating biopolymer involved in important physiological functions. Isolation, characterization, and primary structure of the vanadium chloroperoxidase from the fungus Embellisia didymospora.

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Ultrastructural studies have revealed three different granule types depending on the secretory state of the gland cells. These results provide measures of the anion stabilization due to the hydrogen bond network and inductive effects. Grouping of exposure to particulates and dermal exposure appeared to be less efficient than grouping of exposure to solvents.

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BDAI-1 behaves as a dimer and inhibits the alpha-amylase from the insect Tenebrio molitor at concentrations that have no effect on salivary or pancreatic alpha-amylases. In addition, proper adjustment of the UKF design parameters is crucial for full utilization of the UKF approach for sensor fusion. The inclusion of 0.2M NaCl in the growth medium with tetronasin markedly improved the sensitivity of the screen. Little is known about whether these changes are a specific response to angiotensin II or reveal a more general role of ATP7A. Vacuum cleaner effect, purging effect, active and passive wash out: a new terminology in hydrodynamic stone retrival is arising--Does it affect our endourologic routine?

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Besides, luliberin from the bovine pineal glands injected intraperitoneally to rats led to elevation of the LH blood level. Three complete turns of a 3(10)-helix at atomic resolution: the crystal structure of Z-(Aib)11-OtBu. The great increase in the number of microvessels only partially covered by alpha SMA suggests arteriolization of capillaries as a contributing mechanism in this growth.

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1 mM) acetate was metabolized via the aceticlastic pathway, transforming the methyl-group of acetate into methane. We have used antisera raised against these peptides to monitor the process of regeneration up to postoperative (pa) day 35.

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Since lithium can induce TNF production in human monocytes, we wished to determine if lithium carbonate treatment of neutropenic patients affected by breast cancer results in increased cytokine production. Differential cytosine methylation of repeats and genes is important for coordination of genome stability and proper gene expression. A series of fifty-five 2-aryl-ethenyl-4-aryl-thiazole-5-acetic acids (IV-LVIII) were synthesized and evaluated for analgesic and antiinflammatory activities. One possible reason for this is the lack of a generally available health risk measure that is quick and easy to administer and produces data that is rich enough to inform and direct subsequent employee health promotional interventions.

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But irrespectively of this special problem mortality of cancer of the cervix as well as of the corpus uteri has declined, starting already before 1971, the year in which the official cancer screening programme became effective. The patient underwent laparoscopic ovariopexy for the remaining normal ovary, which was found to be loosely twisted at operation. Mucociliary clearance patterns following endoscopic sinus surgery.

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The compounds, alpha-(N-phenylcarbamoyl)-N-caproylhydrazobenzene and alpha-hydroxy-alpha-(N-phenylcarbamoyl)-N-caproylhydrazobenzene, were isolated by chromatography, identified by mass and NMR spectrometry, and synthesized by the reaction of aniline with phenylbutazone or its hydroxy analog, respectively. Training models are necessary for development of many skills in medical education. Specimens with pronounced fibrosis, fibroblasts, and surrounding collagen fibers expressed positive immunoreactivities for all TGF-beta isoforms and LTBP. In severely hypotensive patients and during cardiopulmonary resuscitation, these sensors no longer accurately reflect arterial blood gases, but act as sensitive real-time monitors of cardiac function and peripheral perfusion. Hence, WHHL rabbits clear LDL from the circulation at an abnormally slow rate, but they clear chylomicron remnants at a normal rate.

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A series of implants retrieved after 11 to 17 years was now studied to establish the actual amount of wear. Individual exposures to day-time noise were moderate to high and showed high variations in different microenvironments except when being in traffic. A 55-year-old man had hydrocephalus caused by a third-ventricular tumor. Isomer identification by metastable decay rates of laser-produced ions.

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These data indicate that genetic factors, possibly related to the immune mechanisms and calcium metabolism, play a role in the pathogenesis of renal adenocarcinoma. Patients who remained stable were slightly younger than those with progressive glaucomatous changes (P less than .05), but initial optic nerve head appearance, initial visual field findings, number of medicines used, medical history, and patient gender or race were not statistically associated with stability or progression of the glaucoma.