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The distances between loci on different arms (LR-distances) and between duplicated loci (LL- or RR-distances) as a function of their distance from the origin, indicate that in slow-growing cells DNA is organized according to the so-called sausage model and not according to the doughnut model. Sham cerclage and local scleral buckle did not decrease blood flow. Septic encephalopathy (SE) is a critical factor determining sepsis mortality.

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Two-dimensional echocardiography showed a downward displacement of the prolapsing motion of the aortic valve cusp during diastole toward the left ventricular outflow tract in one patient, and eccentricity of the coaptation point of the aortic valve without thickening of the cusps in the other. Although emergency liver transplantation may be an only option to rescue in such a case, living related liver transplantation has an advantage in view of urgent organ donation over cadeveric transplantation. Exposure variability in the workplace: its implications for the assessment of compliance.

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Radioimmunoassay of extractable NSE from 10 fresh lung tumours correlated well with the immunostaining results, demonstrating large amounts in two small cell carcinomas (334 and 517 ng/mg protein) and three carcinoids (152, 908, and 1143 ng/mg protein). Epithelial bladder tumor induction in rats with N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide

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Ethacrynic acid, under the conditions of the experiment, abolished distal sodium and chloride reabsorption in the pig. Human seminal plasma contains IGF-I and -II, IGFBP-2 and -4, as well as IGFBP-3 fragments and IGFBP-3 protease activity. The dose-tension response curve for ACh was modified by adenosine, producing a rise of the inhibitory threshold of ACh, and the modification showed a non-competitive interaction of these compounds. Biochemical analysis showed that in strain CG220 toluene was metabolised through the TOL plasmid upper pathway to benzoate and the latter to amphibolic intermediates by the chromosomal encoded ortho-cleavage pathway. This retrospective cross-sectional chart analysis was conducted in a university-affiliated referral hospital.

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Our studies indicate that this protein kinase can not phosphorylate the small subunit of rabbit reticulocyte initiation factor eIF-2 in the presence of its normal endogenous substrate, nor is it activated over a wide range of concentrations of double-stranded RNA. The PGE2 levels increased with the depth of the periodontal pocket, particularly when the depth exceed over 6 mm. In Vibrio alginolyticus, isolated in Octopus vulgaris, a resistance against 9 antibiotics was noted. Significantly greater attenuation of vascular gene expressions of p22(phox) and monocyte chemoattractant protein-1 by linagliptin, compared with sitagliptin, was also observed. Near infrared spectroscopy: in situ studies of skeletal and cardiac muscle.

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The initial response is characterized by computing the distribution of the latency of the first spike and of the duration of the first interval in the ensemble of responses to a large number of stimuli. MPR is the only technique which could depict the thrombus and the best technique to demonstrate the relationships between aneurysm and adjacent structures.

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Neurological disease in human and canine leishmaniasis--clinical features and immunopathogenesis. MPTP-induced damage to sensitive DA-nerve-terminals perhaps by its action as a depot for binding and protracted release and action of the toxin. Relation between the mode of hematoma spreading and the prognosis for hypertensive intracranial hemorrhage We also characterize the atypical chest radiographic findings of this patient and recommend further imaging with computed tomography in unusual patient presentations.

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Metastases to the eye from transitional cell carcinoma of the bladder. Studies determining the relationship between serum vitamin D status and childhood asthma have yielded controversial results.

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Unfractionated heparin, low molecular weight heparin and vitamin K antagonists are anticoagulants currently used for the prevention and treatment of deep vein thrombosis and pulmonary embolism. The pentacyclic triterpenoid 1 was assayed for its in vitro cytotoxicity against Bcap37, HeLa, HepG2, HO-8910, K562, PAA, SGC7901, and P388 cancer cells, as well as for its apoptosis-inducing activity in HeLa cells. Ovulation with 10,000 IU hCG was triggered when the dominant follicle was 10 mm in mean diameter.

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The causative agent, which may be associated with army worm predation of the grass, has not been identified. C3-transferase abolished the decrease in myosin light chain phosphatase activity as well as the subsequent increase in myosin light chain phosphorylation and cell contraction. Various surgical procedures have been attempted so far, but they produce highly invasive stress and high risks.

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Comparison of the effect of penicillins versus erythromycin in preventing neonatal group B streptococcus infection in active carriers following preterm prelabor rupture of membranes. Exploratory and confirmatory factor analyses identified a three-factor model. For baby chest imaging the antiscatter grid is not recommended if only the lung regions are of interest.The K(2)SNR maps based on the new method correspond to those from the beam stop method, and the K(2)SNR from the homogenous phantoms arising from two different approaches also agreed well with each other.

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It then appeared to spread from these few cells to nearby photoreceptors, eventually producing extensive holes in the photoreceptor layer. We advocate incidental cholecystectomy for cholelithiasis in elderly patients as long as the gallbladder is easily accessible and the condition of the patient warrants the additional procedure. Adoptive immunotherapy of malignant diseases was tried using LAK cells induced from peripheral blood lymphocytes with recombinant IL-2 (TGP-3) and fresh human plasma.

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NF2 Schwann cells lack contact inhibition, grow in multiple layers, and show a higher proliferation rate than control cells. These differences were associated with variation in late winter snow cover. The difference in expression of the specific genes may be linked to processes where microtubules have different functions, suggesting that in plants, as in animals, there are differences in the function of the tubulin isotypes. Unconditional logistic was used to determine the most common HPV carcinogenic types.

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These expression patterns suggest that the defence response in the resistant cultivar is strong enough at 20 dpi to restrict further fungus colonization. It seems that they are slightly better after significant advancement. Chemorepulsion of trichomonads by products of neutrophil oxidative metabolism. To act as an efficient thiol-disulphide oxidant the thiolate state of the N-terminal cysteine must be stabilised and the thiolate state of the C-terminal cysteine residue destabilised. Analysis for the frequency of dominant lethals showed that the pheromonal effect results in an increased death rate of the progeny of the treated males.

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Electromyographic and mechanical characteristics of human skeletal muscle during fatigue under voluntary and reflex conditions. The specific targeted genome is recognized and cut by gRNA-directed CRISPR/Cas9 complex, specifically by the endonuclease Cas9. The molecular weight of the minor peak was twice as large as that of the major one. Geographic distribution of multiple sclerosis: An update with special reference to Europe and the Mediterranean region.

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NIOSH presents 2014 awards for significant scientific contributions. Although multiple forms of beta-endorphin were detected in the pars intermedia of L. Working as a neonatology nurse means not only taking care of the very little and sometimes critically ill patients, but also means being confronted with ethical problems. The amino acid and carbohydrate compositions of the microsomal material were in close agreement with values reported in the literatures for the corresponding glycoprotein purified from the plasma. Patients received up to three treatment sessions at 2- to 4-week intervals.

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The resultant transfected cells were able to bind several HLA class II monoclonal antibodies. Patients with type 2 diabetes tend to develop tear film dysfunction. The main IGFBP in serum, IGFBP-3, is known to form a 150-kDa complex with IGFs and the acid-labile subunit (ALS).

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Together, our results provide the molecular and neural basis for the strikingly similar alcohol-responsive behaviors between flies and mammals. Ninety-three patients with typical symptoms of diabetic preretinitis were kept under observation for three to five years (on average 3.9 years), and examined by fluorescein angiography at least once a year.

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Rather, the destructive alterations observed in junctional fold membranes in myasthenia gravis endplates are correlated with decreased acetylcholine sensitivity and to removal of endplate acetylcholine receptors by immunologic processes. Amplifications were observed in different species belonging to the palpalis group. The histidine mutant had specific activity and catalytic characteristics comparable to the wild-type enzyme. Fractures were the second most common injury and occurred equally among boys and girls. Very long chain and long chain acyl-CoA thioesterases in rat liver mitochondria.

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Our results indicate that adenoviral vectors could efficiently transfer CTLA4Ig gene into MSCs and sustain long-term stable expression in vitro and in vivo. Epilepsy as a late sequela of therapy in acute lymphoblastic leukosis--case report Influence of serum proteins on erythrocyte uptake of digoxin and digitoxin. It is suggested the diagnosis may often be overlooked and the extent of injury may be underestimated. These data illustrate the potential of simvastatin to alleviate neutrophilic airway inflammation and remodeling in the transplanted lung and may have additional relevance to other neutrophilic airway conditions, such as chronic obstructive pulmonary disease.

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There was little evidence that differential participation influenced the validity of the study. Xamoterol, by reducing the daytime maximum hourly heart rate and increasing the night time minimum hourly heart rate, significantly reduced the difference between the two compared with placebo. In adult rats with spinal cord transection at T-8, however, the amount of tritiated proline detected in the cervical cord above the site of transection is markedly increased five weeks after surgery, falls to more normal levels by 14 weeks after surgery, and is significantly below normal at 25 weeks after surgery.

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N-methyl-D-aspartate (NMDA) receptors are ligand-gated channels important in neurotransmission which are activated by the combined presence of glutamate and glycine. The information carried by transforming growth factor beta (TGF-beta) signaling molecules induces profound responses in target cells.

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Interpretation of the data from this group of patients is complicated by initially low filtration rates associated with hypercalcaemia and hypercalciuria. Reducing sugars trigger delta-aminolevulinic dehydratase inactivation: evidence of in vitro aspirin prevention. Although T cell clones reactive to various regions of MBP have been found to exhibit heterogeneous TCR Vbeta gene usage in patients with MS, it is unclear whether T cell clones uniformly recognizing the 83-99 peptide of MBP in the context of the same DR molecule would have restricted TCR V gene rearrangements and recognition motifs. UCLA Loneliness Scale (8-item version) scores in a sample of 384 gay and lesbian adolescents support the hypothesis that such youths are especially vulnerable to loneliness. Additional resources devoted to interactive research efforts by laboratory scientists and epidemiologists will provide further enlightenment and continued refinement of our assessment of risks and benefits for specific nutrients and dietary patterns.

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All patients with NSTIs who were treated between January 1989 and June 1994 were analyzed for presentation, etiology, factors important in pathogenesis and treatment, and mortality. Reaction conditions were 5 mumoles pyruvic acid, 2.2 X 10(4) DPM 1-14C-pyruvic acid, leukocytes from 5 ml whole blood, 50 mumoles NaH2PO4, 5 mumoles MgSO4, and 1 mumole MnSO4 at pH 7.4 in 1 ml reaction volume at 25 C.

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This amino-terminal domain is capable of inhibiting cyclin-cdk2 complexes, although it is not a potent substrate for these kinases. The results showed despite the lack of insulin, the 16hr serum starved fibroblasts consumed glucose similar to non-starved fibroblasts control. Anti-acetylcholine receptor antibodies induced in mice by syngeneic receptor without adjuvants. DMSO caused significant apoptosis in two immortalized macrophage celllines constitutively secreting colony-stimulating factor 1 (CSF-1).

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Self-monitoring of blood glucose: an evaluation of the BM test glycemie 20-800 system. Micrometer-scale electrical breakdown in high-density fluids with large density fluctuations: Numerical model and experimental assessment. The appropriate expansion of ACEI/ARB or BB therapy might be necessary to improve their survival. The preload dependence of dP/dt max is influenced by the contractile state of the myocardium. Pharmacokinetics of Second-Line Antituberculosis Drugs after Multiple Administrations in Healthy Volunteers.

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Besides xopC, a second gene of the locus, designated hpaJ, was shown to be coexpressed with the TTS system. We also show that drice expression is specifically controlled by the ecdysone-regulated transcription factor BR-C. Assessment of cumulative external beam and intracavitary brachytherapy organ doses in gynecologic cancers using deformable dose summation.

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Spectrophotometric determination of cytoplasmic and mitochondrial pH transitions using trapped pH indicators. These cells arrest within their replication phase during the stationary stage.

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Relation between various clinical findings in sialolithiasis of the submandibular salivary gland Using as little as 200 microCi of 99m-Tc per patient, in vivo human immune clearance can be determined with a minimal radiation biohazard. In addition, lactoferrin total protein ratios did not appear to be of value in the differential diagnosis of chronic pancreatitis.

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Deficiencies in fibrillin assembly can result in fibrillinopathies, such as Marfan syndrome. Functional role of the Ti plasmid-encoded catabolic mannopine cyclase in mannityl opine catabolism by Agrobacterium spp. bovis BCG, were engineered to express a model tumor antigen, the K(b)-restricted dominant cytotoxic T-lymphocyte epitope OVA(257-264).

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The majority of mice immunized with modified Ehrlich carcinoma cells, L1210 leukemia cells or AA sarcoma cells survived after challenge with a lethal dose of unmodified tumor cells. Molecular Evidence for Convergence and Parallelism in Evolution of Complex Brains of Cephalopod Molluscs: Insights from Visual Systems.

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The gel-like character which is an essential feature of mucus--which cannot otherwise act as transport coupler--is thus a transient phenomenon. Especially H3K36me3, its dual character on gene transcription makes it able to serve as a criterion to distinguish high and low expressed genes. TSP-1 and TGF-beta 1 induced a twofold increase on uPAR expression but only a slight increase on total uPA. It is often difficult to determine the true extent of a burn, but most small thermal burns can be easily evaluated and managed by primary care physicians.