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To discriminate between a cis-acting and a trans-acting mutation, we took advantage of a highly polymorphic TAAA repeat located at the tail end of an Alu repeat approximately 1.1 kb upstream of the ADA gene. Serum specimens were obtained prior initial surgery, and p105 levels were determined using a new developed, polyclonal detector antibody-based human neu quantitative ELISA assay. Medium-frequency current with a galvanic component in the treatment of painful shoulder in hemiplegia The chronotropic and inotropic effects of the anti-anginal agent SG-75 (2-nicotinamidoethyl nitrate) and 1-verapamil were investigated in isolated blood-perfused canine atrial preparations.

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These endpoints were established for different adjuvant agents, but at that moment, rituximab was not considered. These results provide further evidence for an extrarenal synthesis of calcitriol, contributing to the excessive amounts of this metabolite found in the plasma of patients with sarcoidosis.

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A preparation of intermediate filaments isolated from the chicken lens is enriched with a 50,000 dalton polypeptide. Homogenates of salivary glands with infective sporozoites were added to cultures of (i) monocyte-derived adherent macrophages from normal bovine peripheral blood and (ii) macrophages from spleen and bone marrow.

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In-hospital and post-rehabilitation mortality as well as functional outcome at discharge and after rehabilitation were analyzed. Plasma concentrations of bupivacaine and two of its metabolites during continuous interscalene brachial plexus block. The case of a 16-year-old patient is used as an example for the impressive clinical symptoms and the involvement of several organs in this clinical disorder. Channelrhodopsin (ChR)-mediated photocurrent responses are complex and poorly understood, exhibiting alterations in peak current amplitude, extents and kinetics of inactivation, and kinetics of the recovery of the prestimulus dark current that are sensitive to duration and frequency of photostimuli.

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We suggest here to use the 3D multicellular culture conditions for better prediction of the therapeutic outcome in mouse xenograft models. The generalized signal and noise analysis provides analytical prediction of utility of characters evolving at diverse rates of evolution to resolve quartet phylogenies with unequal branch lengths. The differences of serum lipids seem thus to be in connection with the kinds of sport that differ in their energy metabolism requirements.

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Laboratory interproximal access efficacy comparison of a rippled bristles toothbrush and a flat manual toothbrush. We propose that malignant transformation of melanocytes may be more associated with the suppression of melanocytic proteins rather than with new expression of melanoma specific proteins. Diagnostic errors, on the contrary, are made more frequently, especially in general hospitals.

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are one of the most important groups of food-borne pathogens worldwide. Effect of neuraminidase isolated from Erysipelothrix rhusiopathiae on cell cultures

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During the same period no similar pathology was observed in any female or child. Finally, EPA suppressed HT-29 cell growth and this effect was significantly reversed by the addition of GW, suggesting that in part the physiological actions of EPA are the result of PPARgamma activation. Uptake of taurine into subcellular fractions of C-6 glioma cells.

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The clinical significance of delta VO2/work load as a new parameter of exercise tolerance Analysis of male sterile mutations in the mouse using haploid stage expressed cDNA probes. Sources of variation in the milk flow rate and its relationships with milk yield, milk composition, age and stage of lactation in dairy cows. Binary methods for continuous outcomes: a parametric alternative.

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High levels of this bacteriocin, named Linocin M18, were obtained in the stationary growth phase. Weaker staining was observed in type 2 granules and staining was very weak or absent in type 3 and crystalloid-containing granules. These findings suggest that rumination in MDD is associated with select deficits in cognitive control, particularly related to conflict monitoring. In individuals previously exposed to mumps or vaccinia viruses, a substantial proliferative response was elicited.

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Synchronous recordings were made of ventilation, and in 5 subjects an oesophageal electrode was used to record diaphragm EMG. Moreover, electrostatic assembly of DNA probes enables target-initialized release of the probes from the nanoassembly via HCR. Basement membrane zone deposits of immunoglobulins and complement in a patient with pemphigus vulgaris.

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The toxicity of 2-deoxyglucose, a glucose antimetabolite, was investigated in addition to the NMR studies and was found to be consistently higher in multidrug-resistant cells than in the parental drug-sensitive lines. Fertility in relation to individual differences and age needs to be informed and discussed in society as well as in sexual and reproductive health care.

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A 38-year-old man with no significant structural heart disease suffered from one episode of wide QRS tachycardia. More importantly, its superior properties, including a high aspect ratio structure, chemical stability, large specific surface area, excellent electronic or ionic charge transfer, and a specific interface effect, have attracted a great deal of interest in improving current performance and exploring new applications.

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Many were undecided in their attitudes toward their profession and 39 per cent had not joined the Association. The constitutively expressed peripherin isoform is encoded by all nine exons of the human and mouse peripherin genes to generate a protein species of approximately 58 kDa on sodium dodecyl sulfate-polyacrylamide gels. Sonographic examination in six patients and computed tomography (CT) in one provided further information about the degree of extragastric extension. Therefore, agents that stimulate PRRs could be useful for cancer immunotherapy.

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Amantadine specifically inhibits the release of virus particles from cells infected with the Rostock (H7N1) strain of influenza A virus, apparently as a consequence of a membrane protein M2-mediated conversion of haemagglutinin (HA) to its low pH conformation. Utilizing the methods of Pisoni et al., we replicated their findings in a normal control group. This specific lysine preference corresponds to the role of SAS complex in antagonizing the spreading of Sir proteins at silent loci in S.

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It is important to use well what has been well used, to know what is new, and to choose wisely. Studies of factors regulating the ageing of human erythrocytes--III. Influence of circulating antigen on blood pool activity of a radioiodinated monoclonal antibody. Oculopharyngeal muscular dystrophy with limb girdle weakness as major complaint.

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Physical and chemical properties of resin-reinforced calcium phosphate cements. Interestingly, this milder pathology was paralleled by a reduced arginase activity of the parasites. Postoperatively, all patients received vitamin D and calcium orally, which were gradually decreased. The structural and molecular cues that synchronise these events in trypanosomes have started to be elucidated, and intriguingly although similarities to cell cycle events in other eukaryotes can be identified, trypanosomes have also evolved novel solutions to the common challenges faced by dividing eukaryotic cells.

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Laboratory specimens were drawn from the circuit at 10-minute intervals for 1 hour and measured for complement (C3a, Bb fragment) concentrations, blood gases, fibrinogen concentration, platelet count, and hematocrit. All three children with asplenia died in infancy, two with evidence of sepsis.

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Males showed plurihormonal focal pituitary transgene expression with LH-, TSH-, and, unexpectedly, also GH-cell focal hyperplasia and adenoma, associated with increased serum LH, GH, testosterone, and/or IGF-I levels. We provide examples of how these advances in our knowledge could lead to the development of new treatments for psychosis. Myxoma of the left atrium: a cause of retinal artery embolism not to be ignored.

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In particular, studies that identify risk factors for problems common to adolescence, including depression, suicide, and disorders of conduct and eating are reviewed. 2-Aminoethylphosphonate: pyruvate aminotransferase from Pseudomonas aeruginosa.

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Both cis- and trans-5-hydroxy-1-methyl-2-(di-n-propylamino) tetralin (4 and 3) may be classified as central DA-receptor agonists, albeit of lower potency than 6. Unlike their wild-type counterparts, multinucleated myotubes from mouse cells deficient in Rb (Rb-/-) were induced by serum to re-enter the cell cycle. (3) When a muscle is detached following an increase in vertical dimension and allowed to reattach spontaneously, the largest amount of gonial remodeling is observed.

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It is not possible to postulate a poor excretion of fats merely from the high proteolytic activity of the feces because the fecal proteolytic activity and the fat excretion are not inversely proportional to one another. Although HCAD is very uncommon, it should be actively excluded in children and young adults who experience sudden cardiac death. p53 but not erbB-2 expression is associated with rapid tumor proliferation in urinary bladder cancer. I demonstrate mathematically that the predictor variables of improvement and discharge functional score are the same and that the regression coefficients for improvement and discharge functional score will be equal, except for the admission functional score, for which a mathematically defined relation exists.

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There are many theories regarding this gender bias, and prenatal exposure to high levels of fetal testosterone (FT) may be a predisposing factor. Most of the somatic DH sequences found in the published VH-DH-JH structures (the somatic DH segment being defined as the region which is not encoded either by germline VH or JH gene) were assigned to one of the germline DH genes. Circulating dickkopf-1 in diabetes mellitus: association with platelet activation and effects of improved metabolic control and low-dose aspirin. However, they displayed a significant preference for the container touched by the experimenter in the hand conditions, and not in the elbow conditions. Hybridization of intracellular RNAs with 125I-RNA or k3H-kDNA of rabies virus demonstrated marked reduction in both transcription and replication of viral genome in chronic infection as compared with acute infection.

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Before its withdrawal, we investigated the photocontact allergic and phototoxic potential of Neuriplege cream and CPE. Nonhormonal alternatives for the management of early menopause in younger women with breast cancer. These experiments suggest (1) decreased stem cell CFU-C, (2) decreased pb CFU-C, and (3) a serum inhibitor that may be contributing to the depressed pb CFU-C. Summed OP amplitudes were 14.52 microv and 18.38 microv at time 0 and 90 min respectively. By contrast, absentees self-selecting themselves to participate in a group-administered questionnaire reported much higher illicit drug use than regular students from the same schools.

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A case of severe Strongyloides stercoralis infection is described in a patient with renal failure due to bilateral cortical necrosis. Staphylococcal coagglutination reaction in the identification of mycoplasma Elevated blood acetaldehyde in alcoholics with accelerated ethanol elimination. Attitudes and beliefs about emergency contraception among patients at academic family medicine clinics. Effects of tiemonium iodide (tiemonium, 20 micrograms/kg), mepenzolate bromide (mepenzolate, 20 micrograms/kg), butylscopolamine bromide (butylscopolamine, 50 micrograms/kg) and atropine sulfate (atropine, 10 micrograms/kg) on the colonic motility in dogs were evaluated using a balloon method.

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500 cases of lower limb lengthening using a personal technic in achondroplasia In the female rat, the binding activity to FSH receptors and the in vitro FSH activity of eCG are similar (about 0.005 X eFSH).

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The main objective of this study was to ascertain whether serum miR-181b expression is correlated with that of liver hepatitis B virus (HBV) DNA and disease progression in chronic hepatitis B (CHB) patients. One- and two-year results including juxtafoveal and extrafoveal CNV. Third order rate constants (k3) are calculated for solvolytic reactions in a wide range of compositions of acetone-water mixtures, and are shown to be either approximately constant or correlated with the Grunwald-Winstein Y parameter.

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Projections from these sites are described and are generally similar to those obtained by degeneration methods. Because of the colocalization of opsin and retinochrome in the dark, we believe that the two metapigments participate directly in chromophore exchange. A preliminary result of urinary disposition of meperidine and its metabolites in the rat is presented.

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Effect of esophageal intraluminal mechanical and chemical stressors on salivary epidermal growth factor in humans. Analysis of the reversal in breast feeding trends in the early 1970s. Much of the transitional experiences were similar to those reported for Japanese and European migrants to the United States, such as the rise of cancers of the lung and colon in males.

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Glycoform composition of serum gonadotrophins through the normal menstrual cycle and in the post-menopausal state. Age changes on bone size and mass in two strains of senescent rats. Since the first microscopically visible changes of follicle initiation occur around 62 days gestation, these results suggest that TGF beta 1 expression may be a signal for follicle initiation.

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Sulfated modification of the polysaccharides from Ganoderma atrum and their antioxidant and immunomodulating activities. Plasma samples were analyzed for angiotensin II concentration by radioimmunoassay.

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Cellular mechanisms of insulin resistance, lipodystrophy and atherosclerosis induced by HIV protease inhibitors. Adhesive interactions between cells and the subendothelial extracellular matrix take place at several stages during tumor progression and metastasis. We have recently observed that chitotriosidase, a chitinolytic enzyme, is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients (Hollak, C. Brain dopa and DA levels were elevated maximally between 0.5-2.5 hr and 1.0-2.5 hr, respectively. We have found that wound fluid blocks the response of thymic lymphocytes and of two cloned T-helper cell lines (D10 and HT2) to exogenous human recombinant IL-2.

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Characterization of in vitro T lymphocyte colonies from normal mouse spleen cells: colonies containing cytotoxic lymphocyte precursors. A significant positive correlation was found between whole-saliva Cy-A and both plaque and gingival overgrowth scores.

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Effect of interleukin-2 on the growth of malignant soft tissue tumor explants in diffusion chambers Labral tears occurring in the vascular zone may be amenable to arthroscopic repair rather than debridement.

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Sectioned root dentin surfaces were treated with either a NaF solution for 10 min or a fluoride varnish for 48 h and then exposed to 1 M acetate buffer pH 5.8 for 20 h. Platelet aggregates are then trapped in the pulmonary microcirculation. Spectrin, fodrin, and TW-260/240 form a group of structurally and functionally similar but not identical high molecular weight actin-binding proteins from chicken erythrocytes, brain tissue, or intestinal epithelial brush borders. This higher distinguishing ability of the cysteamine-containing film architecture was proven with information visualization methods to treat the impedance data. However, the proliferation and maturation of chondrocytes in the zone of proliferating chondrocytes and in the upper hypertrophic zone continued and resulted in the formation of a thickened growth plate.

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Histological study of motor innervation to long nuclear chain intrafusal fibers in the muscle spindle of the cat. Automatic evaluation of left ventricular (LV) function using equilibrium radionuclide angiocardiography requires an edge detection algorithm to correct and reproducibly delineate the left ventricle. It appears to offer advantages over freehanded techniques and previously described devices used for the same purpose.

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Soreness was evaluated at baseline and at 0.5, 3, 4, 7, and 10 d after exercise. Focal right inferotemporal atrophy in AD with disproportionate visual constructive impairment.

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High resolution fast spin echo T2 weighted and constructive interference in steady state sequences were performed in 23 patients with a 1.5 Tesla magnetic resonance unit. These antibodies could be used for passive immunization or in vivo immunodiagnostics. Analysis of functional and biochemical changes in feline cerebral hemispheres after subchronic haloperidol administration

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In order to investigate the attenuation of vOka in skin, we made chimeric pOka and vOka recombinant viruses from VZV cosmids. From the above results, CS, as a dehydropeptidase-I inhibitor apparently caused increases in some peptides consisting mainly of Asp, Glu, Gly and Ala in patients with impaired renal function. Plasma folates were severely depleted at the end of pregnancy even when folic acid was present in the diet. One of the most damaging effects of severely weakened and under-resourced health systems is the difficulty they face in producing, recruiting, and retaining health professionals, particularly in remote areas. The myeloblastoma, visible as a left apical mass on chest radiogram, resolved completely after six days of intensive AML induction chemotherapy.