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Growth inhibitors against tumor cells in Cordyceps sinensis other than cordycepin and polysaccharides. Efficacy and pharmacologic data of second-generation tyrosine kinase inhibitor nilotinib in BCR-ABL-positive leukemia patients with central nervous system relapse after allogeneic stem cell transplantation. Administration of minocycline-HCl with local drug delivery system was introduced as a part of initial periodontal therapy following microbiological and immunological examinations.

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The patient must be fully informed and given time to reach a decision. The metastability of subjective experiences based on resonant dynamics occurs when bottom-up patterns of neocortical excitatory activity are matched with top-down expectations as adaptive dynamic pressures.

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Linkage between oligomerization and DNA binding in Drosophila doublesex proteins. Silicon-based surface plasmon resonance sensing with two surface plasmon polariton modes. Although some caution is needed in the very old, advanced age per se does not represent a contraindication to metformin use.

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Propofol is a safe and widely used intravenous anesthetic agent, for which additional clinical uses including treatment of migraine, nausea, pain and anxiety have been proposed (Vasileiou et al. There is no universally accepted, precise definition, nor standardisation in terminology and classification of halitosis.

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Here, we show that such an example is highly unlikely when applied to resting cerebral metabolism, and can be identified in experimental data by testing for a bimodal distribution of partial correlation values. SJSA-1 implanted mice were imaged before and 2, 6, 9 and 13 d after initiation of bevacizumab or saline treatment.

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XIV Congress of the Spanish Society of Family and Community Medicine. These events are influenced by prostanoids and corticoid hormones. Potential effects of illness features were explored, including rapid cycling, medication, alcohol or other substance dependence, duration, and mood state. The advantages and complications of alveolar ridge reconstruction methods, and the efficacy and surgical method of soft tissue graft are reviewed.

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Binocular scleral search coil eye movement recordings revealed a defect not only of muscle relaxation but also of maximal muscle contraction. The aim of the present study was to evaluate antibacterial activities of combination of oleic acid and gentamicin against MRSA, in both free and liposomal forms, and in comparison with vancomycin. Maintaining constant spray tip-to-surface and atmospheric sampling interface capillary-to-surface distances during an imaging experiment was found to also be critical. (2) To explore the correlation of OPN and CD44 expression of gastric cancer. Protein synthesis with membrane-bound polysomes and albumin messenger RNA from livers of mutant mice.

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Anti-Thy 1.2 monoclonal antibody linked to ricin is a potent cell-type-specific toxin. No changes were observed in plasma AVP levels and PRA after intracerebroventricular injection of ANP (0.3 nmol/kg). Percutaneous deployment of a polytetrafluoroethylene (PTFE) graft to repair a pseudoaneurysm produced by a graft to graft anastomotic dehiscence. Multiple surgical procedures were necessary for complete control of this difficult problem. Rheumatoid factor and secondary rheumatoid disturbances in patients with haemophilia.

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A large enzyme tracer with a relatively low binding constant can, therefore, provide a more sensitive assay. Intrajejunal feeding and gastric decompression via a multi-lumen tube provided effective conservative treatment of duodenal ileus together with gastric decompression. This paper proposes a method for mobile robot localization in a partially unknown indoor environment. To assess change in intraocular pressure (IOP) in patients with neovascular age-related macular degeneration (NVAMD) receiving intravitreal aflibercept injection (IAI) or ranibizumab in VEGF Trap-Eye: Investigation of Efficacy and Safety in Wet AMD (VIEW) 1 and 2 studies.

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Neither Western blot nor myograph or mRNA analysis showed involvement of the other MAPKs studied. Respiratory effects of preoptic-anterior hypothalamic electrical stimulation during sleep in cats.

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Arterial Blood Pressure (BP) was measured through ambulatory blood pressure monitoring (ABPM) at the end of the first, second and sixth weeks. The statistics obtained using nonlinear methods did not surpass those got with linear ones. On the other hand post-coupling techniques are subject to product inhibition. Exposure pathways, human receptors, algorithms, and input variables used by each state in the calculation of acceptable human health risks are identified and reviewed within the context of environmental policy and regulatory impacts. Alpha-L-fucosidase activity in patients with ductal cholelithiasis

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Lower brainstem projections to the motoneurones of the nasolabialis muscles, which show rhythmic respiratory-phased activity were studied in the rabbit using the horseradish peroxidase (HRP) technique. Transarterial approaches to primary and secondary hepatic malignancies. Its specificity was confirmed in immunohistochemical, cellular localization, Western blot and immunoprecipitation experiments, as well as by showing a statistically significant decrease of endogenous CRNDEP expression in the cells with transient shRNA-mediated knockdown of CRNDE. Catatonia, gastric hyperacidity, and fatal aspiration: a preventable syndrome.

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The suppository for the every third-day BP was randomized to PGB or HVB. Inhibition of prostaglandin action and bone resorption by copper.

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This work proposes a self-consistent assessment methodology for quantitative evaluation of any combination of diagnostic features, with the immediate goal of quantitatively assessing the discriminating power in diabetic patients of features derived from ultrasound backscatter from myocardium. One hundred and ninety-seven members of 28 kindreds with multiple endocrine neoplasia type 2A (MEN 2A) were screened for RET proto-oncogene exon 10 and 11 mutations.

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The voices of wrath: brain responses to angry prosody in meaningless speech. No significant changes in bladder pressure or residual urine were shown.(ABSTRACT TRUNCATED AT 400 WORDS) This retrospective study shows that BCS plus radiotherapy is the predominant treatment in routine practice for stage I breast cancer in Geneva, with the same effect on survival as mastectomy.

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In this project, we developed an approach whereby a frequently played computer game can be used to assess a variety of cognitive processes and estimate the results of the pen-and-paper trail making test (TMT)--known to measure executive function, as well as visual pattern recognition, speed of processing, working memory, and set-switching ability. Muscle interstitial fibroblasts are the main source of collagen VI synthesis in skeletal muscle: implications for congenital muscular dystrophy types Ullrich and Bethlem. The tube is relatively easy to insert and well tolerated, and its use is a less expensive alternative to parenteral hyperalimentation. These data show that reactive metabolites of trichloroethylene can be formed in human and rat hepatocytes and bind covalently to discrete hepatic proteins, and suggests that in rats, but not humans, that one of the targets is CYP2E1. The mescaline has shown to be active both on behaviour (increasing the spontaneous motility) and on biochemistry (decreasing the total cholinesterase activity).

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A 43 year-old man with presumed progressive multifocal leukoencephalopathy developed difficulty recognizing objects and faces in the presence of adequate visual acuity and visual fields. Lymphosarcoma with lymphoblastic leukemia in a New Zealand white rabbit. This review will discuss the various clinical trial endpoints that have been used or proposed with a focus on their potential utility, as well as possible pitfalls that investigators should consider in the design of such studies. Electronic analysis of the duodenal spike increase which accompanied pressure rises demonstrated correlations between increases in spikes, intraluminal pressure, and dose. This study thus demonstrates the potential for direct investigation of the kinetic behaviour of an immobilised enzyme on a lipid bilayer through an efficient transduction system.

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This study suggests a defect in IC-stimulated B cell suppressor activity in RA leading to decreased ability to suppress antibody and further IC formation. The in vivo absorption spectrum of the giant spheroplasts did not have peaks typically observed for bacteriochlorophyll a. The pancytopenia responded dramatically to treatment with steroids.

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Heterogeneity of breast cancer clinical characteristics and outcome in US black women--effect of place of birth. The correlation between sperm motility and the social status was revealed to start after 10 weeks of age. Expression of the alpha subunit of human chorionic gonadotropin is specifically correlated with tumorigenic expression in human cell hybrids. This technique gives excellent results and is particularly indicated in cases of choledocic lithiasis complicated by cholangitis in order to clear up the infection and send the patient in for surgery in ideal condition.

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The CPP32 transcript is highly expressed and most abundant in cell lines of lymphocytic origin. Cerebral blood flow changes with acute cocaine intoxication: clinical correlations with SPECT, CT, and MRI. The localizing role of vitiligo in these exceptional cases could represent a more complex disorder of the dermo-epidermal junction. The patients with marked lung abnormalities as well as those with positive bacterial culture of sputum had normal antibody levels. Interaction between muscle stiffness and stretch reflex sensitivity after long-term stretch-shortening cycle exercise.

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The determination of the HLA antigens may be used in the practice for the institution of a proper treatment of the different variants of systemic lupus erythematodes. Intraradicular lumbar disc herniation: case report and review of the literature. Medical school hotline: tropical cyclone Haiyan/Yolanda medical relief mission: perspectives of John A. The detection limit was 10 micrograms AFP per litre when using only monoclonal antibodies in the assay.

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Treatment of the animals with neomycin for 10 days protected them from death of severe forms of enterocolitis. Effect of L-carnitine on motility and acrosome reaction of human spermatozoa. These microsatellite sequences mutate at a higher rate than that of bulk DNA.

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In both patients repeated exercise tests yielded different results, because the chest pain and S-T segment depression occurred at different work loads with large differences in heart rate-systolic blood pressure product. Four of the cases were treated conservatively with nasogastric aspiration and intravenous fluids and it is suggested that this should be the treatment of choice in the majority of cases.

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Characterization of germination and activation of Bdellovibrio bdellocysts. This study supports the hypothesis that sulfinpyrazone metabolites (in particular the sulfide) rather than the drug itself affect platelet function when administered therapeutically. The patients with corneal abrasions experienced a significant reduction in pain immediately after application of the lens, so that no pressure patch was necessary. Subsequently, SMAD2 was identified as a common target of miR-212/132 and was found to be negatively regulated by miR-212/132 at the mRNA and protein levels.

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We used a micromethod for cytogenetic analysis from single haematopoietic colonies to study two adults with chronic myelomonocytic leukaemia (CMML) and a boy with juvenile chronic myeloid leukaemia (JCML) carrying distinct chromosome abnormalities, 7q-, der(21), and trisomy 21. One of the key factors for a further development and scale-up of the approach is the understanding of the mechanism underlying scCO2 -assisted phase separation. It occurs mainly in children but occurrence in adults has also been reported. Re: New guidelines to evaluate the response to treatment in solid tumors (ovarian cancer).

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There is a small association between dietary patterns and change in fat mass in mid-childhood. Salmonella typhi, Shigella flexneri and Shigella dysenteriae 1, Enterotoxigenic Escherichia coli) and on our better characterization of the immunological parameters of mucosal protection, it is likely that a limited number of vaccines controlling diseases such as typhoid fever, bacillary dysentery and cholera-like E. Immunopharmacological actions of lumin (II): Effect of lumin administration in NZB X NZW (B/W) F1 mice

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non-drainage after cholecystectomy for acute cholecystitis: a retrospective study. p28 inhibitory activity fluctuates during the cell cycle with maximal levels in G1 and accumulates in G1- and G0-arrested cells. Localization of the genes for silk fibroin in silk gland cells of Bombyx mori. The first one, electromechanical, consists of a glucose sensor, a computer and an insulin pump. Semi-quantitative cytokine analysis revealed that the mRNA expression of TNF-alpha and INF-gamma in spinal cords and spleens of actarit treated active EAE rats was significantly reduced compared with vehicle treated EAE rats.

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Clinical aspects and prevention of dermatitides from chemical exposure coli atpE gene Shine-Dalgarno (SD) sequence, to the translational initiation regions of IL2 and INF beta increased the expression of both these genes by a factor of 6-10. Selective pivaloylation and diphenylacetylation of cyclomalto-oligosaccharides. We pay particular attention to the latest results concerning APC structure, APC regulation and substrate recognition, and we discuss the implication of these findings in the understanding the APC function.

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Invariants reveal multiple forms of robustness in bifunctional enzyme systems. During the evolution of mammals, the endometrium has developed for one reason only: to implant an embryo in the uterus. Changes in Pitx2 expression are evident in mouse mutants with laterality defects. It has been shown that self-reactive T cells can be detected in the periphery. A total of 3442 genes, called the set M AD, were found to be either up- or down-regulated by at least 2-fold between the two phenotypes.

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The use of stable, activable tracers has been studied in applications to establish the performance of waste treatment plants and detect causes of irregular or improper functioning of individual plant processes. Steroid-protein interaction: substrate specificity of 20 beta-hydroxysteroid dehydrogenase.

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The southern clade includes ticks from the southeastern and middle-eastern regions of the United States. Remote estimation of phytoplankton size fractions using the spectral shape of light absorption.

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From that date and onward the treatment of burns has continuously been improved based on results from experimental and clinical research. Human monocytes isolated from peripheral blood responded with increased thromboplastin expression upon stimulation in vitro with three mycobacterial antigens: tuberculin purified protein derivative and sonicates of Mycobacterium boviS BCG and Mycobacterium leprae. Flucloxacillin associated neutropenia in children treated for bone and joint infections.

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In 1968 we evaluated a study group of 623 healthy women 30 to 49 years old who had evidence of a regular intake of phenacetin, as measured by urinary excretion of its metabolites, and a matched control group of 621 women. Minimal salt medium with glucose and semisynthetic Minca medium were the most suitable for K99 production. Anti-cancer agent adriamycin (ADR) has demonstrated high anti-tumor efficacy. There was no obvious difference between blank group and mock group. The present study is part of a larger project, Drama-Ger (Lepp et al.

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Increase of neutrophil alkaline phosphatase in the parents of trisomy 21 children. Guidelines for the use of thrombolysis in acute myocardial infarction--second consensus report 1994.

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In TRIS buffer, the formal potentials of adsorbed FMN and FAD were also pH-dependent, however, with invariance in the pH range 4.5 to 5.5. Experimental induction of cementogenesis on the enamel of transplanted mouse tooth germs. Both loss of function and overexpression of ttk affect the fates of the SOP progeny. Theoretical and practical bases of hybridization techniques (Southern blot, Dot blot, In situ hybridization, Filter in situ hybridization FISH, Hybrid Capture Assay, HCA), amplification techniques (polymerase chain reaction, PCR and variants--multiplex PCR, reverse transcription PCR, real-time PCR) and sequencing techniques(sequencing analysis, single-strand conformation polymorphism--SSCP) are discussed. Hemosorption is effective prior to the occurrence of signs of clinical decompensation.

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A solution to the endoscopic removal of difficult bile duct stones. The binding of the title benzodiazepine enantiomers and its modulation by warfarin and bilirubin were studied by chromatography on human serum albumin (HSA) immobilized on Sepharose 4B, and also by a combination of ultrafiltration and circular dichroism (UF-CD) methods.

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Substituted five-membered heterocycles such as thiazoles and imidazoles were identified that serve as replacements for peptide fragments of the lead. In all patients, cardiac valve surgery was carried out together with coronary reconstruction in the form of a single to triple bypass. All these subjects started to manifest clinical symptoms compatible with AIDS. While it shares some organizational features with other sensory systems, the auditory system has some unique functions that impose special demands on precision in circuit assembly.

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Cytoplasm of blastomere-like nucleolar amoebocytes is overloaded with yolky inclusions at various stages of digestion. Pentafluoropropen-2-ol (PFP) was prepared by the reaction of hexafluoroacetone (HFA) with Mg/TMSCl. Although the basement membrane (BM) phenomenon is considered a good test to differentiate between systemic (SLE) and discoid lupus erythematosus (DLE), our observations question its reliability. The possibility that the similar supersensitivity, which occurs in thyroidectomized rats, might be associated with elevated corticosterone levels was investigated by measuring fluorimetrically the plasma levels of corticosterone in thyroidectomized rats. These were found to give less correct estimates of drinking and smoking habits than those obtained from population controls.