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These results revealed that mitochondria pathway may involve in cadmium-induced apoptosis, and cadmium caused the PTP opening possibly through its binding to thiol groups of ANT. The effect of fasting and time of day on the urinary excretion of chondroitin 4/6 sulphate, dermatan sulphate and four chondroitinase ABC resistant glycosaminoglycans.

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Involvement of Endoplasmic Reticulum Stress-Mediated C/EBP Homologous Protein Activation in Coxsackievirus B3-Induced Acute Viral Myocarditis. A minimum follow-up of 1 year after stent removal was considered for final analysis. The effect of chronic renal insufficiency on cyclosporine nephrotoxicity. Maprotiline poisoning: a case of cardiotoxicity and myoclonic seizures. Treatment of drug resistant A-V reciprocating tachycardias with multiprogrammable dual demand A-V sequential (DVI,MN) pacemakers.

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The masked condition was designed to simulate a flat mild hearing loss. Enhancement by progesterone of lysergic acid diethylamide inhibition of the copulatory response in the female rat. These results show that Ts act by inhibiting the activation of Th, thereby suppressing Th-dependent responses generally. Signal detection theory and the psychophysics of pain: an introduction and review.

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To analyse the results of delayed evaluation of European teaching sessions using a questionnaire provided by the French College of Anaesthesiologists. Combination of electron microscopy and the thioflavine S technique in studies of the spinal cord microvasculature.

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They report the clinico-diagnostico-instrumental factors leading to pre-operative diagnosis of pseudocystic-pleural fistula. Results suggest that readers encode these inferences into memory only minimally, but that they can make use of a cue word that represents the inference (e.g., dead) both at the time of an immediate test and in delayed cued recall.

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As a common neurological movement disorder, restless leg syndrome (RLS) is often seen in patients with multiple sclerosis (MS). Furthermore, continuous treatment with ipriflavone for 14-33 days resulted in an increase in the area of bone-like mineralized tissue accompanied by an increase in the secretion of osteocalcin. This review summarizes the current knowledge of miRNAs, recent advancements in miRNAs associated with exercise and addresses their role as biomarkers for exercise-related biological responses.

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Treatment consisted of symptomatic relief using low dose anxiolytics and antidepressants, and psychological interventions. Recent work has demonstrated that individual differences in working memory capacity measured using a reading span task are related to ability to recognize speech in noise. Enzymes A and C were isolated from the nuclear fraction, but this fraction did not contain enzyme B. Minor pancreatitis after a Billroth II gastric resection for gastroduodenal ulcer Compared with control values, a significant decrease in the serum cortisol until CPB could be demonstrated, followed by a significant increase persisting for at least 6 days postoperatively.

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When fresh mitomycin-C treated BALB/C lymphocytes were added to the cell mixture, the mixed lymphocyte response against BALB/C cells by the treated DBA/2 lymphocytes was abolished. The inhibitory effect of doxycycline was most pronounced in the immunized rabbits. ECGs exhibited nonspecific ST-T wave changes, sinus arrhythmia, occasional ventricular and supraventricular premature complexes and 2(0) AV block. One hundred and forty-eight premenopausal women aged between 45 and 49 years. Acute contact allergic dermatitis as a consequence of using degmin

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The remaining excess sensitivity is concentrated among individuals with less liquidity. To assess the functional integrity of monocytes in patients with cervical carcinoma, cytotoxic potential of peripheral blood monocytes and their ability to secrete interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) after activation with different stimulating agents were studied. In addition to the action of glycine as an inhibitory neurotransmitter, structural alterations of myelin may be important in the pathogenesis of the neurologic disorder of glycine encephalopathy. Colonisation was shown to be an evanescent phenomenon, and female consorts often had different mycoplasma flora to the males.

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Recycling of epidermal growth factor-receptor complexes in A431 cells: identification of dual pathways. Three-dimensional (3-D) ultrasound is a widely available, low-cost imaging modality that may be used to provide real-time feedback to needle steering robots. Fragmentation of the stones was obtained in one session in 4 patients. The effect of immobilization on skeletal fluorosis was studied in growing rabbits.

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Gene expression and/or distribution were assessed by real-time PCR, Western blotting, and/or immunohistochemistry. Electrical spinal cord stimulation for spastic movement disorders. Seeds and reaction products were examined chemically and by X-ray diffraction and electron microscopy. In normal newborn mice, abundant expression of PlGF messenger RNA was detected in the lungs during saccular division but was rapidly downregulated after alveolarization was complete. Factors associated with increased survival after surgical resection of glioblastoma in octogenarians.

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The fitted SOS curves in our study population show a plateau period in both genders for younger ages followed by an increase phase beginning at the age of 12 in girls and 14 in boys. The low-molecular-weight heparins have been shown to be efficacious and safe for the treatment of venous thromboembolism in several clinical trials, including many patients in the older age brackets. The results of this study indicate that prolonged intubation is not quite safe and that serious complications occur in several per cent of cases. The present study aimed to evaluate the effectiveness and safety of hyaluronic acid gel for the treatment of volume loss or contour deficiency.

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After a longer follow-up a clinical diagnosis was established by the help of physical status, biochemical liver function tests and--in the cases of suspected liver disease--liver biopsy. Increased frequency of the uncommon allele of a tumour necrosis factor alpha gene polymorphism in rheumatoid arthritis and systemic lupus erythematosus. Investigators might assume a simple linear model, take the average of the ordinary least square estimators of slope within each treatment group, and use the standardized difference between these two averages as the test statistic at each interim analysis.

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We describe our evaluation and surgical management of a patient presenting with seizures, headaches, and CMD. To assess the satisfaction and recovery of women undergoing sterilization with a permanent birth control device (Essure micro-insert). Anti-inflammatory drug intake and the risk of ulcer complications. The clinical parameters examined were the quantity and organoleptic characteristics of the expectoration, coughing, and body temperature.

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A surface antigen that identifies ocular dominance columns in the visual cortex and laminar features of the lateral geniculate nucleus. These effects were most pronounced when IL-4 was present during the early phase of culture. Failure of medical suppression necessitated total abdominal hysterectomy and bilateral salpingo-oophorectomy. Thereafter, clinical symptoms improved gradually and he was removed to the professional hospital to continue rehabilitation for gait disturbance on hospital day 147.

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However, we unexpectedly observed that normal ferrochelatase activity in hepatic and dermal cells of wild-type mice is sufficient to prevent liver disease and significant skin photosensitivity. To evaluate the ability of cilostazol, an antiplatelet and vasodilating agent, to promote axonal regeneration in streptozotocin-induced diabetic rats, the time until beginning of regeneration (initial delay) and the axonal regeneration rate of the sciatic nerve were estimated using the pinch test, and ornithine decarboxylase activity was measured in dorsal root ganglia.

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In some cases a significant decrease of OR positivity was observed after three months storage, and a complete loss of OR immunostaining after 12 months. The constraint tests based on local surface and local sensor visibility are applied first to individual range images. The light-sensitive species Zhong Dou 24 was used to receive long-time sunshine, short-time sunshine, and natural sunshine treatment.

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To evaluate the effects of intrathecal injection of rapamycin on pain threshold and spinal cord glial activation in rats with neuropathic pain. They also suggest that glucose flux might determine the levels of molecules implicated as signals in catbolite repression.

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However, prefrontal cortex amphetamine treatments did attenuate the sensitized locomotor effects of subcutaneous amphetamine that developed over trials/days. The aim of the study is to assess the frequency of sexual dysfunction in men after myocardial infarction (MI). Six of the 7 clones were distinct variants by immunological criteria using antisera derived from whole cells or purified surface glycoproteins.

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Rat brain slices released spontaneously and after challenge with A23187 LTC4-like radioimmunoactivity. alpha 2-Antiplasmin and alpha 2-macroglobulin have been studied during the menstrual cycle, pregnancy and parturition in healthy women, and during use of various types of contraception in both healthy and diabetic women, and compared with a reference group of healthy men and women.

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Limb-somite relationship: effect of removal of somitic mesoderm on the wing musculature. To determine whether the presence of an on-scene medical control physician (OSMCP) alters the management and outcome of out-of-hospital nontraumatic, nonasystolic cardiac arrest (CA) patients.

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Intra- and extrahepatic shunts in liver cirrhosis--evaluation by means of combined invasive nuclear medicine methods Expression of ORF13a was investigated by analysis of glucuronidase (GUS) activity in transgenic tobacco containing an ORF13aGUS fusion. Report from the Health Technology Assessment Unit of the Basque country (Osteba). Therefore, it is suggested that the adaptive response can be observed in human hepatoma cell lines, which is first documented through this study.(ABSTRACT TRUNCATED AT 250 WORDS) It supports the possibility that the relationship between blood pressure and PAI-1 may reflect the overall effect of the insulin resistance syndrome (in particular hyperinsulinaemia and hypertriglyceridaemia) rather than a direct effect of blood pressure on the fibrinolytic system.

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GnRH agonists are effective in the treatment of endometriosis, as well as other disorders, such as advanced prostrate cancer, precocious puberty and uterine leiomyomata. Thus transoesophageal echocardiography failed to detect an apical wall motion abnormality when the probe was placed at the midpapillary level.

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Furthermore, we observed differences between Jurcat cells and PBML in their relative content of fatty acids and in the incorporation of PA and AA into triacylglycerols and phospholipids. Evidence from recombinant bunyavirus studies that the M RNA gene products elicit neutralizing antibodies. Quantitative determination of c-erbB-2 in human breast tumours: potential prognostic significance of low values.

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This study revealed a significant association between lack of response to 5-fluorouracil and mitomycin and mutations affecting the L2/L3 domains of the p53 protein. Interobserver variability in interpreting contrast left ventriculograms (CASS). Genes (including SRY) on the conserved or added region of the Y evolved functions in male sex determination and differentiation distinct from the general functions of their X-linked partners. We sought to provide the world medical community with a web portal that may be used as a clearinghouse providing the outlet for dissemination of high quality WWW educational products. The glycoconjugates from A cell membranes which bound to the lectin and were eluted with 0.01 M N-acetyl-D-galactosamine were analyzed using cylindrical or slab gel electrophoresis in the presence of sodium dodecyl sulfate.

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Noneffect of electronegative gases on pulsed laser-induced optical surface damage thresholds. Conformational changes caused by the binding of calcium to S-100 protein fractions were detected by means of differential and fluorescence spectroscopy. The physiologic factors controlling lower esophageal sphincter (LES) function are interrelated in a complex fashion and include the autonomic nerve supply, gastrointestinal hormones, and specific characteristics of the circular smooth muscle at the esophagogastric junction.

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To compare the Diabetes-39 (D-39) with six multi-attribute utility (MAU) instruments (15D, AQoL-8D, EQ-5D, HUI3, QWB, and SF-6D), and to develop mapping algorithms which could be used to transform the D-39 scores into the MAU scores. In addition, PE is made via the CDP-ethanolamine pathway, in which the final reaction occurs on the endoplasmic reticulum and nuclear envelope. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. The increase of suicides in recent years has had a significant impact on the years of life lost and can be used as a useful indicator of performance in Hong Kong. Follow-up checks were applied to 327 patients who had had pregnancies terminated, between 1973 and 1975.

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Our laboratory has isolated and characterized a FAEES/carboxylesterase cDNA from human eye and heart (G12). The growth of Public Psychiatry Fellowships (PPFs) has reached a new developmental stage, providing a wide array of academic partnerships and educational opportunities in psychiatric leadership and administration. Among outpatients with CAD, self-reported anginal symptoms consistently predict mortality irrespective of differences in age, race, education, or clinical comorbidities. Coelocentesis is a new technique that could be used as an alternative method early in the first trimester of pregnancy. A similar pathophysiology could be responsible for the trend seen in vulvovaginal and hepatic carcinomas.

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Sixty-five percent of the women reported histories of some type of abuse or neglect during childhood. Traumatic rupture of retrosternal goiter: a rare case of acute superior mediastinal syndrome. As patients receiving maintenance electroconvulsive therapy (MECT) age, many will acquire medical illnesses that may complicate their course of ECT and the treatment of their underlying psychiatric conditions.

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Lipid nanoparticles as an emerging platform for cannabinoid delivery: physicochemical optimization and biocompatibility. Imposing additional restrictions upon individual preferences considerably simplifies the analysis by relying on a loss function.

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For 168 children (94 2-year-old children and 74 5-year-old children), mean dietary intakes were calculated from 7 days of written dietary records, entered and analyzed using the Minnesota Nutrition Data System. We hypothesized that the microscopic changes leading to use-dependent adaptations in brain might cause neurometabolite changes that could be detected with quantitative proton MR spectroscopy. Spinocerebellar projections were studied in the turtle, Pseudemys scripta elegans, by both anterograde (injections of 35S-methionine into various spinal segments) and retrograde (injections of horseradish peroxidase into the cerebellar cortex) tracing techniques. Surveillance for recurrent endometrial carcinoma: development of a follow-up scheme. Stroke is a syndrome characterized by a sudden neurological deficit caused by intracranial hemorrhage or ischemia.

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In addition, we suggest that the anterior medial superior frontal region is related to aspects of self-referential semantic processing and that the inferior parts of the anterior cingulate as well as the medial orbitofrontal cortex is related to affective processing, in this case pleasantness evaluation of the stimuli regardless of explicit semantic content. Hyperfractionated and hypofractionated radiation therapy for human malignant glioma xenograft in nude mice.

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Since then the relationship has been reversed with higher rates in the non-Jewish group. Exposure to trans-RA, but not to 1-cis-RA, induced the medial epithelia to undergo hyperplasia, and addition of EGF enhanced the effect. Starting from a short description of the Swedish situation, some major current insights into the complexities of interaction between biological and psychosocial variables in explaining CHD are discussed.

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After PGF2 alpha-IE 3.0 micrograms or PGE2 1.5 microgram for 8 weeks, HRP passed through the tight junction of non-pigmented epithelial cells and there was dilatation of rough-surfaced endoplasmic reticulum in the non-pigmented epithelial cells. Quantitative analysis of cervical musculature in rats: histochemical composition and motor pool organization. A chi-squared analysis was performed and no significant difference between the distribution of cases occurring during the full moon phase and that outside of these periods was found. We report on a 56-year-old Caucasian female with a history of thrombosis, thrombocytopenia and the detection of anti-cardiolipin antibodies. Potentiation of colonic contractility to cholecystokinin and other peptides.

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Participation was noted more often in goals than problems identified in case study vignettes. Women receiving clonidine had significantly better quit rates than men receiving clonidine at all follow-up visits. On preincubation of NTF with VVA2, NTF was found to inhibit VVA2 hemolytic activity by inducing VVA2 oligomerization in the solution in the same manner as liposomes. Influence of Cancer-Associated Endometrial Stromal Cells on Hormone-Driven Endometrial Tumor Growth. If sudden death in subjects without cardiac failure is usually attributed to arrhythmia, in chronic cardiac failure it is often the result of sudden collapse, the mechanism of which is not well known.

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Direct high-performance liquid chromatographic profiling of phospholipids, their plasmalogens (as 2-acyl lyso analogues) and sphingolipids is probably the method of choice for the diagnosis of patients with deficient plasmalogen biosynthesis caused by peroxisomal abnormalities. We conducted a double-masked study to evaluate the effect of epidermal growth factor on epithelial wound healing and recurrent erosions in alkali-burned rabbit corneas. On the contrary, the dietary fatty acid intake greatly modified the fatty acid profile of plasma membrane phospholipids. Demonstrating multiple PARs on microglia may enhance the attractiveness of PARs as therapeutic targets in neuroinflammatory disorders.

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The reliability and criterion-related validity of ratings of posteroanterior (PA) spinal stiffness made using reference values for comparison have not been investigated. These two pieces of evidence suggest that, although many determinants may contribute to reactivity in mixed leucocyte culture or PLT, an immunodominant determinant associated with the DR beta chain may be the most important single factor in the assignment of Dw specificity. Especially in the perichondrium there was a rapid proliferation of fibroblasts and monocytes.