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Unexpectedly, furin complementation did not change the status of MT1-MMP expression or activation, but instead resulted in the production of mature and bioactive TGFbeta1. Calculated static compression forces at the L5/S1 spinal disc were consistently above the NIOSH Action Limit of 3400 N for strong subjects when the cart load reached 225 kg. CSI 3.0: a web server for identifying secondary and super-secondary structure in proteins using NMR chemical shifts.

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Diabetes is associated with hypertriglyceridemia and it has been suggested that the intestine contributes to this elevation. Fecal ion concentrations seemed independent of diet but were related to fecal weight and the amount of colon and ileum removed.

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Ultrastructural study of GERL in beige mouse alveolar macrophages. Piperacillin was the most active penicillin in both populations (MIC90: 25.8 and 21.8 mg/l). This person became ill in Africa, exhibited clinical manifestations of boutonneuse fever and had a significant rise (greater than or equal to 8-fold) in IgM titer against spotted fever-group rickettsiae.

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An interaction between the vascular reninangiotensin and the sympathetic nervous system is present. Spathiphyllum wallisii plants were used to study the effect of chilling stress under high illumination on photosynthesis and chlororespiration. Ten patients with LC metal-on-metal hip implants were the subjects of analyses after a mean follow-up time of 13.9 years.

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Diagnostic value of various biological markers in postoperative recurrences For maximize our data base for such comparison we used two neurochemically and behaviorally distincts strains of mice, BALB/c and C57BL/6. Molecular characteristics of extracellular matrix-associated glycosaminoglycans in the endothelium. Safety of radiofrequency catheter ablation of accessory atrioventricular pathways. Also, females expressed greater hostility and morality-conscience guilt than males.

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The thymus-derived lymphocyte nature of the responding cell was further suggested when treatment of immune spleen cells with anti-Thy 1.2 serum and complement eliminated antigen response. A group of 21 healthy volunteers were also enrolled in this study. Carnitine 100 mg/kg/d lead to an increase in urinary excretion of propionylcarnitine, but did not affect plasma methylmalonate levels. The encephalitic disease is discussed in relation to encephalitic syndromes induced by other neurotrophic viruses. The killing by human polymorphonuclear leukocytes of several species of bacteria, some of which were catalase positive, was examined in vitro in aerobic and anaerobic conditions.

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In the present work, we compare different de facto standard supervised and unsupervised procedures to identify and classify variants potentially related to muscular diseases, and we discuss results in terms of statistical and biological validation. On the other hand, ecabet increased the capacity of gastric mucosa to synthesize PGE2, while cimetidine showed no effect on this parameter either in the presence of absence of ecabet.

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Immunoreactivity for Fos protein following 30 min of sensory and behavioral experience with foster pups was measured in different brain areas of nulliparous female Balb/c mice who were intact, ovariectomized, or selectively depleted of olfactory bulb noradrenaline. To evaluate the duration of the effect of mepivacaine when hyaluronidase is injected immediately prior to the end of pulpal anesthesia. The inactivation of blood cells and lethality of mice (LD50/30) were also monitored for 30 days after irradiation. Linolenic acid did not potentiate hindpaw oedema induced by carrageenan. Long-term exposure to opiates induces tolerance to the analgesic effect and dependence.

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First trimester molar pregnancy: nonspecific ultrasonographic appearance. Patients had fenestration of a 2 mm x 3 mm segment of the medial aspect of the optic nerve sheath. Chemical modification of vesamicol binding sites and frequency augmentation-potentiation in neuromuscular transmission.

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This dose caused an immediate fall in blood pressure, associated with a nonsignificant increase in heart rate. Cytotoxic effect of a combination of bluetongue virus and radiation on prostate cancer. That of overshoot against calcium concentration in the presence of 75 mM sodium was 22 mV/tenfold change. The tumor in all seven patients with gross disease accumulated 125I-TYR(3)-octreotide. The MV beamformer is shown to be less sensitive to wider transmit profiles required to reduce the transmit crosstalk artifacts.

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These findings reinforce a role of TGF-beta as an anabolic bone growth regulator, and suggest that its function may be modified by other local or systemic agents that can also affect bone cells. Calculated volumetric blood flow rate, however, was not significantly different from normal in eyes with no retinopathy, BDR, and PDR, and was significantly decreased from normal in patients with PDR who had been treated by panretinal photocoagulation. Afferent resistance is negligible in the hypotensive range and increases progressively in the normotensive range.

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Its application has particular value in the study of dental polymeric materials. This study clarified the knowledge of and attitudes on the use of genetic information for medical purposes among the general public of Japan. The impact of lumbar spinal surgery is commonly evaluated with three patient-reported outcome measures: Oswestry Disability Index (ODI), the physical component summary (PCS) of the Short Form of the Medical Outcomes Study (SF-36), and pain scales. LDL-Apheresis for the treatment of hyperchylomicronemia-induced pancreatitis Small children, older than one year of age, can bear as many drugs as mature people can.

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The RAS effector RAS- and RAB-interacting protein 1 (RIN1) activates its own downstream effectors, the small GTPase RAB5 and the tyrosine kinase Abelson tyrosine-protein kinase (ABL), to modulate endocytosis and cytoskeleton remodeling. The electrode was attached when the cervix was dilated 4 to 6 cm. The interactions of exogenous cell-permeable ceramides and ceramide-1-phosphates in modifying DNA synthesis and signal transduction were investigated in Rat-1 fibroblasts. Expression of Ia like (HLA-DR) antigens on human alveolar macrophages. Because adipose tissue is essential in energy homeostasis and also plays a role in life span determination, we decided to investigate the function of sirtuin members in fat.

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All study participants had completed undergraduate courses in health-related areas. To study whether these areas might have different projections, we characterized synaptic inputs from the rostral and caudal SC to inhibitory burst neurons (IBNs) in anesthetized cats.

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The potential for recurrent ROP after a single 0.2 mg ranibizumab injection for posterior ROP requires vigilant monitoring. Intraocular pressure and aqueous humor dynamics in rabbit and primate with d- and 1-adrenergic compounds. The method of graded physical exercise with the plotting of the functional curves and calculating of the functional coefficient (FC) was used in the study.

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This deficit has been seen to occur when A and B are made up of two different auditory, visual, or vibrotractile stimuli. A novel urethrocystography device is proposed which facilitates the procedure and is more safe in relation to complication danger. We hypothesized that IgE regulates surface FcepsilonRI expression by DCs in vivo and that, consequently, anti-IgE therapy decreases FcepsilonRI expression by DCs.

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Tetracycline at a low concentration stimulated the expression of ampicillin resistance in certain strains of Haemophilus influenzae. Groups of intercorrelating processes were determined by factor analysis. However, the exact mechanisms of arsenite-induced human skin carcinogenesis remain to be defined. Influence of anesthesia, postanesthetic state, and restraint on superior mesenteric arterial flow in normal rats. Effects of bradykinin on ion conductances in NG108-15 neuroblastoma x glioma hybrid cells recorded with patch-clamp electrodes.

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We have constructed recombinant (r) fowl pox viruses (FPVs) coexpressing chicken type I interferon (IFN) and/or hemagglutinin-neuraminidase (HN) and fusion (F) proteins of Newcastle disease virus (NDV). An evaluation of the treatment effectiveness of the Chicago Health Outreach Acupuncture Clinic. Involvement of canine oral papillomavirus in generalized oral and cutaneous verrucosis in a Chinese Shar Pei dog.

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The importance of other classical pyogenic pathogens (Staphylococcus aureus, gram negative bacteria and others) in community acquired pneumonia Ethnic differences in use of inpatient mental health services by blacks, whites, and Hispanics in a national insured population.

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PKCbetaII/HuR/VEGF: A new molecular cascade in retinal pericytes for the regulation of VEGF gene expression. Our data indicate that inclusion of 67Ga-ECT in the routine examination is unnecessary in cases with bronchogenic carcinoma. This will provide minimally invasive surgical option for varicocele and we can expect more potential cosmetic benefit and less morbid. The extent to which prenatal drug education is included in school health education has not been addressed. Indeed, proper solubilization is one of the most important factors for a successful analysis.

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Receptor expression was largely independent of the activation state of the cells. It is possible that the two regions of the gene in which these mutations map define portions of the molecule which are in contact when folded in the native configuration. Correlation between DNA repair of embryonic fibroblasts and different life span of 3 inbred mouse strains.

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Protein synthesized in vitro from cloned cDNA is processed upon import into isolated chloroplasts, indicating that mature AS alpha subunits are active in plastids in vivo. Seven days later the clinical signs of tricuspid valve insufficiency and concomitant right heart failure had disappeared.

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Our results suggest that the circadian gene human Clock may play an important role in carcinogenesis by inhibiting apoptotic cell death via attenuating proapoptotic signaling. I-125 implant and supervoltage irradiation for treatment of T0-2 or T3 carcinoma of the prostate. The results indicate that Korsakoff but not non-Korsakoff alcoholics have neuropsychological deficits on tests which have demonstrated medial temporal-lobe/diencephalic dysfunction in humans and non-human primates.

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Maternal ECG recorded by internal monitoring closely mimicking fetal heart rate in a recent fetal death. Recognition of two Dermatophagoides pteronyssinus-specific epitopes on antigen P1 by using monoclonal antibodies: binding to each epitope can be inhibited by serum from dust mite-allergic patients. Pre-cuing target location reduces interference but not negative priming from visual distractors.

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Within the context of a wider study exploring perceptions of helpful and unhelpful factors in the therapeutic process, a sub-sample of 36 in-depth interviews with clients, therapists, and therapists who considered themselves to have been abused as children included a focus on abuse-memory experiences. When administrated subcutaneously, JTP-2942 was about 80 times more potent than TRH in the antagonization of reserpine-induced hypothermia, and when administrated intravenously it was about 16 times more potent than TRH in the potentiation of flexor reflexes. A study of quadriceps contracture-causing factor by the analysis of muscle injection according to medical records

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The human response headform is modeled as a spherical brain of nearly incompressible material, a covering of linear elastic dura, a linear elastic spherical skull, and a layer of nonlinear scalp material. The granulocytes expressed mRNA coding for nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-4 (NT-4), but not neurotrophin-3 (NT-3). The optical and electrochemical measurements show that the molecule has a remarkably small HOMO-LUMO gap compared with its triphenylamine precursor.

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These observations suggest that thymus-dependent cell-mediated immunity plays an important role in the host response to E. The change in mechanical properties of reheated phosphate-bonded investments One week after injury, the fetal and adult animals were sacrificed, and tendons were histologically and mechanically evaluated. Use of stones in a captive group of Guinea baboons (Papio papio). In theory, this would limit their use in a clinical setting after limb salvage treatment for osteosarcoma.

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The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial showed that, in patients who had experienced a stroke or transient ischemic attack, treatment with high-dose atorvastatin over a 5-year period significantly reduced the risk of a subsequent stroke. This is the case for the components of the CRISPR-Cas interference complexes, which degrade invading nucleic acids in a sequence homology-dependent manner in many prokaryotic species. Abnormal suppression of TGF-beta could enhance the sensitivity of epithelial cells to apoptosis associated with interferon-gamma in DSS-induced colitis. The incidence of severe hyperlipidemia during therapy of patients with acute lymphoblastic leukemia (ALL) who received prednisone and asparaginase was evaluated. Regulatory proteins with a sense of direction: cell cycle signalling network in Caulobacter.

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The direction of the dipole around the peak of N20m from median nerve electrical stimulation was opposite to these directions. Identification of CCAAT/enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene. Multiple myeloma is the most common disease characterized by paraproteinemia.

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DTZ N-demethylation, the major metabolic pathway in man, was strongly increased by treatment of animals, patients, and hepatocyte cultures with rifampicin and other inducers of the P-450IIIA subfamily. Results showed clear qualitative and quantitative distinctions between records of 23 distracted normals and those of 15 schizophrenics. These defects, which are suggestive of vessel wall dysfunction on maintenance hemodialysis, may contribute to the high incidence of arteriopathy and thrombotic disease observed in this group of patients. Three cases of lateral neck tumors caused by thrombosis of the external jugular vein have been presented.

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Each participant acted as his/her own control in a repeated measures design, receiving one of two possible treatments (25 g glucose vs. Polysulfone resins for denture bases (3): compressive and tensile strength Disodium cromoglycate inhibited histamine secretion from rat peritoneal mast cells, was less active against the hamster cells and completely ineffective against those of the mouse.

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In most cases, and in the absence of postoperative complications, the operative repair can lead to a recovery of the sexual life in patients with preoperative sexual dysfunction, while, in most cases, it does not affect patients with a preoperative normal sexual life. However, at that time the diagnosis of diverticular haemorrhage was mostly one of exclusion. Additionally, extra steps were taken to distinguish loosely and tightly bound protein, the latter of which may be fully or partially denatured. The similarity of the membranlytic effects of saponins towards fungi and erythrocytes is descussed. Effect of streptozotocin-induced diabetes on prostaglandin production by rat cerebral microvessels.