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Membrane effects of retinoids: possible correlation with toxicity. Recognition of these various manifestations is essential to proper treatment. The cause of the kaliuresis does not appear to be an increased systemic plasma potassium concentration, an increased plasma level of aldosterone, intake of citrate, or an elevated excretion of sodium. It may be hypothesized that the implantation of 5-fluorouracil-loaded microspheres in the wall of the cavity resection did increase the overall survival, but the present study was not designed and sufficiently powered to demonstrate this.

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PNP-deficient lymphoblasts have PPRibP contents characteristic of normal lymphoblasts, about 20 to 25 pmol/10(6) cells. There is a pronounced lack of data examining HIV risk among particularly vulnerable subpopulations of women who use and inject drugs, including women who have sex with women, transgender women, racial and ethnic minority women, and young women.

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Mercury residues in fathead minnows, Pimephales promelas Rafinesque, chronically exposed to methylmercury in water. Genetic variation associated with differential educational attainment in adults has anticipated associations with school performance in children. In response, this paper also discusses the basics of a Human Factors Engineering (HFE) approach as a step towards overcoming this problem and offers a challenge to device users and design companies (manufacturers) to follow HFE principles in order to improve the efficiency of operation and reduce errors during device use. Here we present methods to study the phenotype and mechanisms of immune suppression by B cells in different mouse models of EAE. New time-frequency method for cerebral autoregulation in newborns: predictive capacity for clinical outcomes.

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When a slow event rate was used the mean relative desynchronization of alpha rhythm and duration of ERD increased. This suggests an inhibitory effect on a pathway occurring late in G1, or close to the G1/S boundary. The 3 normal inhibitory phases of reciprocal inhibition between extensor and flexor forearm muscles were markedly reduced on the spastic side of patients. Moreover, Immunoprecipitation assay results also indicated that Yap binds directly to TEAD2 and LATS2 inhibition-mediated dephosphorylation increased the YAP1/TEAD2 association, leading to YAP1/TEAD2 transcriptional activation, which in turn upregulated cell invasion in HCC cells. Traumatic dislocation of the knee is an uncommon orthopedic injury affecting primarily young males who have been subjected to major trauma.

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from the domestic reindeer (Rangifer tarandus) in northern Norway. Specific questions which await investigation with clinical research are elaborated. Seventy-five per cent of the women and 50 per cent of the men had discrimination scores equal to or better than 92 per cent at the age of 70.

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This pressor effect induced by ANG II was abolished by simultaneous administration of ANF (3 micrograms/kg i.c.v.). Proportion-of-distance measurement is presented as a more valid alternative to end-of-range measurement. Eruption through the oral mucosa was fairly rapid and the deficit noted in the bone emergence phase was reduced to one day. In addition, we found that a 5-fold increase in IGFBP-5 mRNA levels observed in RRO-I cells, which eventually leads to a similar increase in the secreted levels of IGFBP-5, was partly due to an increase in the stability of IGFBP-5 mRNA.

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Alpha-interferon suppresses food intake and neuronal activity of the lateral hypothalamus. Purification of a proteinase (Ac5-proteinase) and characterization of hemorrhagic toxins from the venom of the hundred-pace snake (Agkistrodon acutus).

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National guidelines state that health care professionals (HCPs) should advise patients on the importance of maintaining a healthy weight. The correct recognition of HSE, and distinguishing it from other forms of encephalitis, brain abscess or mimicking disorders early in the course of evaluation facilitates treatment decisions when neurologic complications occur.

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The patient is a 55-year-old female with a history of multinodular goiter. Since total skeletal muscle MAO activity is the largest source of MAO in the body, it is possible that the decrease in muscle MAO activity may lead to excessive quantities of biogenic amines that could adversely affect neural activity.

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Ultrastructural and immunophenotypic differentiation of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor (GM-CSF). Fifty percent of patients in our series did not have long-term response to propranolol for subglottic hemangioma, highlighting the importance of close follow-up. This report documents the disturbance in gastrointestinal motor function in a patient with selective cholinergic dysautonomia that occurred following acute infectious mononucleosis.

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The increased haemolytic activity by actin was concentration-dependent, detectable in early-exponential-phase growth, and associated with increased concentrations of secreted HlyA by Western blotting. The purposes of this study were to investigate whether vasoconstrictive endothelin-1 is released by cocaine and to elucidate the mechanisms involved. Electrogenesis of increased norepinephrine sensitivity of arterial vascular muscle in hypertension.

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The kinetics of interleukin 1 secretion from activated monocytes. However, more spleen cells were required to lyse nucleated target cells than were required to produce comparable lysis of the erythrocytes. An unusual complication of brachial plexus block and heparin therapy. Two cell lines (SCL-I and SCL-II) derived from squamous cell carcinomas of human skin were investigated during 4 years in culture.

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Sighing breathing is observed in subjects suffering from anxiety with no apparent organic disease. Large conformational adjustments in both nogalamycin and the DNA are necessary to form a stable, intercalative complex. Multiple meningiomas in a patient with Rubinstein-Taybi syndrome. The over-expression of miR-421 promoted gastric cancer cell growth and inhibited apoptosis of the BGC-823 gastric cancer cell line. Pathogenic role of hepatitis B virus in hepatitis B surface antigen-negative decompensated cirrhosis.

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However, the exact pathogenetic details are still largely unknown. The role of the N-(hydroxymethyl)melamines as antitumour agents: mechanism of action studies. Colistin is an antibiotic that was introduced many years ago and was withdrawn because of its nephrotoxicity. This movement could be blocked by the addition of millimolar AMP-PNP but was not affected by concentrations of vanadate up to 150 microM, suggesting that poleward flux may be driven by a microtubule motor similar to kinesin.

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Renal function was assessed in relation to urinary tract anomalies and with outcome after ureteric re-implantation. Seven such carriers were identified by pedigree analysis and protein-tolerance testing. The repair of potentially lethal damage (PLD) was not increased by BHT at the two temperatures investigated (5 and 20 degrees C). The possibility that the birefringence gradient found in such cells is due to changes in the disk membrane-pair spacing is investigated using previously published glycerol imbibition data (Kaplan et al., 1978. Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain.

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However, the putative cellular sources and the mechanism underlying the induction of IL-6 in these tissues are presently unknown. By partially blocking the back focal plane of the objective lens, the schlieren microscope produces an image with patterns that correspond to spatial derivative of refractive index in the specimen.

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Experimental evidence for saltatory propagation of the Mauthner axon impulse in the tench spinal cord. Spleen cells from LAF1 mice were stimulated in a microculture system with T and B cell mitogens or antigens of timothy pollen.

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Sinonasal disease (SND) is a common finding in subjects with Cystic Fibrosis (CF). Studies with the inhibitor carbonyl cyanide m-chlorophenylhydrazone show this ATP to be generated as a consequence of oxidative phosphorylation. A cell-sparse zone of dense neuropil is located between the two cellular areas.

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The fibrosing myositis is an unusual fibromatosis of the muscle, which arose within the tongue muscle. Magnetic resonance imaging (MRI) revealed a Gd-DTPA enhanced lesion from the level of the medulla oblongata, involving the reticular formation, to that of the vertebral body C2. Thus, bNOS represents an attractive antimicrobial target for treatment of anthrax and other infectious diseases. In three cases the examination brought to light a diagnosis of tuberculosis and in one of a tumoural origin. Characteristics of dihydroxyphenylalanine/5-hydroxytryptophan decarboxylase activity in brain and liver of cat.

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Results indicated that di-n-butyl phthalate (DBP) and di-2-ethylhexyl phthalate (DEHP) are the only detectable PAEs which ranged in 24.9-68.3 mg/kg and 39.1-71.9 mg/kg in this study. Administration of 5 mg and of 10 mg/kilogram bodyweight was followed by a fall in blood pressure by 15-45 per cent up to 2 minutes after the injection. Glucose 6-phosphate dehydrogenase deficiency and sickle cell anemia: frequency and features of the association in an African community.

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In recent years a widespread application of molecular biology techniques has led to identification of genetic polymorphisms associated with hypertension and cardiovascular events. Leaves showed different responses that depended on root temperature.

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During freezing the selective precipitation of substances in the medium may provoke a pH shift and lead to sperm damage. Results of these experiments indicated that ICR injected into eggs remained infective for pigs and suggest replication of ICR in the first-passage eggs. 27 hypertensive subjects, mean age 45 years, who were free of antihypertensive medications. A comparative morphometric study of auto- and alloplasty of peripheral nerves

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Exploration of the area revealed a benign fibrotic lesion encircling the pacemaker lead within the right atrium. Leptin suppresses Porphyromonas gingivalis lipopolysaccharide interference with salivary mucin synthesis. The effect of CO2 induced pH changes on the response of airway smooth muscle to theophylline was studied. Multiphoton ionization mass spectrometry of chlorophenols as indicators for dioxins.

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The medical records of 56 patients who received a transtracheal oxygen catheter between January 1987 and June 1992 at our institution were reviewed for demographic data, diagnosis leading to catheter placement, complications related to catheter use, reason for catheter removal, and duration of use. Neck muscle endurance was significantly lower for the groups reporting monthly and weekly pain compared with the never/infrequent group.

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This is thought to occur secondary to a germline mutation in the DICER1 gene. CCSV seems to be a safe and immunogenic alternative to calf-lymph derived vaccine for both vaccinia-naive and non-naive people.

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aeruginosa O groups can be characterized on the basis of their geographical distribution in the world: 1 degree Nine serogroups with worldwide distribution: 0:1, 0:2, 0:3, 0:4, 0:5, 0:6, 0:8, 0:9 and 0:11. C3a activates the respiratory burst in human polymorphonuclear neutrophilic leukocytes via pertussis toxin-sensitive G-proteins. Treatment patterns and affecting factors in breast cancer patients over 65-years of age Patients with biliary strictures diagnosed during endoscopic retrograde cholangiopancreatography were submitted to double brushing cytology.

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Sex, quality of care, and outcomes of elderly patients hospitalized with heart failure: findings from the National Heart Failure Project. The aim of this study was to assess the value of cervical dilatation with hygroscopic cervical rods (Dilapan-S) in patients with difficult embryo transfer.

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By means of the corrections, even samples containing more than 65 per cent nuclear fragments could be evaluated with sufficient accuracy. As persons with HIV live longer, data regarding the epidemiology of colorectal cancer are required to optimize the long-term management of these patients.

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Screening for IgG4-type anti-nuclear antibodies in IgG4-related disease. This study supports further evaluation by qNPA of this gene panel as an alternative or complimentary method to existing protein biomarkers to identify ovarian cancers with a hypoxic phenotype.

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Velocity was reduced distal to an aortic coarctation and it was increased at the site of narrowing caused by thrombosis in a deep vein. Does preoperative orientation and education alleviate anxiety in posterior spinal fusion patients?

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Produced by the International Continence Society Working Party on Urodynamic Equipment. The various causes of hyperkalemia in the absence of renal failure in insulin-dependent diabetes are discussed, notably the renin deficiency hypoaldosteronism syndrome. Intracellularly was indicated depression by delay or blockage of postsynaptic discharge and diminution of epsp in motoneurons. Profiles of groundwater and sediment properties were collected at three sites in Bangladesh with an inexpensive sampling device that is deployed by modifying the local manual drilling method. Contrast sensitivity in deep anterior lamellar keratoplasty versus penetrating keratoplasty.

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A 48-year-old man developed a plasmacytoma in the subcutaneous pocket of a titanium covered pulse generator that had been inserted sixteen months previously. Interpretations by two independent observers were correlated with findings from histologic examination, digital subtraction angiography, computed tomography, and clinical follow-up. Know your community resources: facilitating the life review through group reminiscence.

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musfiblp mRNA induction was earlier and significantly greater in BALB/cJ than A/J macrophages. The microarray study revealed, that the angiogenesis and homing-related genes were mostly influenced by BC and AA in investigated cells. Their data demonstrate the importance of oxidative modification of (unknown) adhesion molecules in regulating inflammation and lymphocyte homing. The surgeon was found to be a hepatitis B surface antigen carrier, hepatitis B e antigen (HBeAg)negative, but with antibodies to HBeAg.

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Dysregulations of IL-1 and IL-8 were found in psoriatic lesions. Although these bodies are not very prevalent, they appear with increasing frequency as the age of the animal increases from 12 to 28 months. TBS represents severe and refractory manifestations with a high rate of restenosis. Effects of nitrogen source on the synthesis of the UV-screening compound, scytonemin, in the cyanobacterium Nostoc punctiforme PCC 73102. carinii-induced macrophage inflammatory protein 2 production by alveolar macrophages.

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Alterations in bone structure at the metaphyses and corticoperiosteal ossifications can suggest malignant affections. The technique allows single base pair resolution and rapid typing, with a concomitant reduction in the potential for human transcriptional typing errors.

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The Myopia Progression Study was funded by the National Eye Institute to test more rigorously the efficacy of bifocals, compared with single-vision glasses, in slowing myopia progression in children with nearpoint esophoria. These findings show that the pathological substrate of familial supraventricular arrhythmias consists of a diffuse involvement of the entire conduction system, bearing resemblance to pathological findings in elderly subjects with acquired sick sinus syndrome. Measurement of parathyroid hormone in patients with primary hyperparathyroidism undergoing first and reoperative surgery. The role of memory and metaphor in the creation of meaning in personal narratives, however, has not been sufficiently explored in nursing literature. These analyses suggest that particular emphasis should be placed on the ear in public health campaigns geared toward the prevention and early detection of nonmelanoma skin cancer.

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Intravascular ultrasound (IVUS) can measure the instantaneous circumference or diameter of the arteries during a cardiac cycle, and so investigate human arterial elasticity in vivo. Current treatment strategies for patients with severe and refractory PPH are limited by either technical difficulties and high mortality or cost. This proliferation is not enhanced by Con-A, is not linked to a lymphoid contaminant, and is specifically inhibited by an anti-IL-2R mAb.

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Rethinking percutaneous paravalvular leak closure: where do we go from here? Exogenous surfactant preserves lung function and reduces alveolar Evans blue dye influx in a rat model of ventilation-induced lung injury. Isolation of mutants deficient in acetyl-CoA synthetase and a possible regulator of acetate induction in Aspergillus niger. Ultrastructural localization of P2 protein in actively myelinating rat Schwann cells. In contrast, homes with intermediate RH levels had very variable mite-allergen content.

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The data indicate that recombination is reduced between DNA markers on nondisjoined chromosomes 21. The methylene blue dye also penetrated through the interface between amalgam and root end cavities, and there were varying size gaps between the root end cavities and amalgam. He was diagnosed as having RA with vasculitis, according to interstitial pneumonitis, cutaneous nodules and polyneuropathy. Structure and activity of largazole, a potent antiproliferative agent from the Floridian marine cyanobacterium Symploca sp. However, the mechanisms of this physiologic phenomenon are not fully understood.

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Pancreatobiliary decompression for pancreatitis: special reference to pancreas divisum. Corticotropin releasing factor and vasopressin were measured in major brain regions including the neurohypophysis in spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY) during development of hypertension. The multiple factors affecting plasma renin activity in essential hypertension.