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We conclude that it is possible to generate clinically meaningful diagnostic evidence from electronic sources of patient data. In our series of 30 patients, followed for a mean duration of 10.3 years, 11 developed associated retinal detachments. It has also been demonstrated that intravascular platelet aggregation will increase transiently the hydraulic conductivity of pulmonary exchange vessels. Eight patients with recurrent malignant gliomas refractory to previous nimustine chemotherapy were entered in this study.

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The X-chromosomal human biglycan gene BGN is subject to X inactivation but is transcribed like an X-Y homologous gene. Our study revealed intranuclear inclusions in choroidal cells, a previously undocumented finding in progressive outer retinal necrosis.

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In 2 eyes of 2 patients, a single schisis cavity, with an inner leaf in a dome-shaped configuration, was present. Meningeal involvement and cranial neuropathy often mimic other more common conditions. From June 1, 1993, through February 28, 1994, one arthroplasty surgeon saw 148 outpatients (age range, 15-86 years) after hip arthroplasty (163 prostheses). Evaluation of the effect of the work load on gynecological morbidity Phase I trial on sms-D70 somatostatin analogue in advanced prostate and renal cell cancer.

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Fatal myocarditis in a young female caused by coxsackie virus group B type two. This case may be one of the first reports in the literature on a piriformis muscle enlargement documented by CT and MR imaging. mRNA for GM-CSF, interleukin 3 (IL3), G-CSF, and IL4 could not be detected in the stromal cells. Mutations and/or abnormal expression often lead to constitutive dimerization and kinase activation of FGFRs, and represent the primary mechanism for aberrant signaling. Partial sequence analysis shows that the insert contains a nucleotide sequence encoding the complete amino acid sequence of calcitonin.

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Active transport, permeability enhancers, enzymatic degradation, and absorption in various tissue sections can be explored. The possible implications of these observations in relation to synaptic efficacy and neuronal microcicuitry are discussed. Moreover, the analytical performance of ferrocene-based glucose biosensors (FBGBs) is summarized and the problems associated with the construction of GBs and the future trends are discussed. In addition, familiarity with both the appearance of the normal prostate and the changes caused by BPH is necessary when staging patients with known prostate cancer.

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Using five economis strata, white men below and above age 55 in the poorest group had rates 2.6 and 3.8 times higher than those in the richest. Cefoperazone demonstrated activity comparable to gentamicin against Pseudomonas aeruginosa and other pseudomonads.

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Ototoxicity resulting from the combined administration of potent diuretics and other agents. The concepts of intraneural and extraneural pathology are put forward and related to assessment and treatment. Previous studies suggest a role for loci on chromosomes 11p and 17p in the pathogenesis of MB. An antigonadotropic decapeptide was extracted from bovine pineal glands, purified by ultrafiltration and Sephadex G-25 gel-filtration chromatography and isolated by serial semi-preparative high performance liquid chromatography. The results of coinfection studies indicated that the E1A gene products of highly oncogenic Ad12 could not complement the lack of induction of cytolytic susceptibility by E1A-minus Ad5 virus in infected cells and also could not block induction of this infected-cell phenotype by Ad5.

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Veliko Turnovo, Gabrovska, and Trapezitsa products were shown to be most contaminated. We describe here an atypical case of histiocytic sarcoma in the rat and we compare the nature of these neoplastic cells to other species. The inferior lobe consists primarily of a nucleus ventricularis of densely packed cells surrounding the lateral recess of the third ventricle, and a peripherally situated nucleus diffusus consisting mostly of scattered neurons.

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Purification and characterization of a methyltransferase from Aspergillus parasiticus SRRC 163 involved in aflatoxin biosynthetic pathway. In anaesthetized artificially ventilated guinea-pigs from two breeds were produced histamine-induced bronchoconstrictions after pretreatment with acetylsalicylic acid (ASS) and/or para-amino-methylbenzoic acid (PAMBA). Moreover, we report that the EGFR transactivation signal involves the EGFR ligands amphiregulin, HB-EGF and TGFalpha as well as the metalloproteinases ADAM 10, 15 and 17, depending on the cellular system. Juxtaposition of the cytoplasmic domains of the alpha and gamma subunits during assembly is responsible for this loss of ER retention. It was shown in cats by the method of conditioned defensive reflexes that phenamine (0.5 mg/kg), sydnocarb (3 mg/kg) and katinon (1 mg/kg) accelerate realization of the conditioned defensive reflex, but abolish the differentiation of visual stimuli.

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The parameters obtained for the hidden state model uncover characteristic properties of the system including synchronization, oscillation, switching, background activity and correlations. Only a subpopulation of AL expressed viral F proteins after exposure of these cells to RSV. The age at treatment (soft tissue situation/estimated growth/biological potential of the bone), therapeutic concept (palliative vs. We present a new technique which was carried out on 43 patients which caused symptomatic improvement in those patients. The daily oral steroid dosage (prednisolone 25.0 mg/day or more) and blood urea nitrogen level 2 months after transplantation were the only factors with relevance to the occurrence of ONF.

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Susceptibility of DTH to immunosuppression by cyclophosphamide treatment was also assayed in street rabies virus-infected mice and in adoptively-sensitized recipient mice. From competitive blocking assays using eight murine anti-T4 mAbs coupled with quantitative flow cytometry, at least five and possibly seven different epitopes can be recognized on the T4 molecule. It was demonstrated that the hemolytic activity of the lymphocytes of patients was significantly higher, than in the control group.

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The impact of increasing dose on overall survival in prostate cancer. Changing the spatial pattern of TFL1 expression reveals its key role in the shoot meristem in controlling Arabidopsis flowering architecture. In this study, we examined the impact of a mutation in the extracellular domain of KIT on mast cell tumorigenesis. Characterization of their substrate specificity, separation by Mono Q chromatography, and comparison with the mitogen-activated protein kinases. Subsequently, the importance of controlling the immunological system was stressed.

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Development and assessment of new cellulose membranes for blood purification. Although the histologic changes in lymph nodes in patients infected with the human immunodeficiency virus-1 (HIV-1) are well described, the histology and resulting clinical symptoms of hyperplastic nasopharyngeal lymphoid tissue (NPLT) in these patients are not widely known, particularly to pathologists and oncologists.

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Effects of granulocyte-macrophage colony-stimulating factor and erythropoietin on leukemic erythroid colony formation in human early erythroblastic leukemias. In this study we describe the induction of a dendritic phenotype associated with cytoskeletal rearrangement in activated human peripheral blood T cells stimulated with monoclonal antibody SPV-L7 to LFA-1 alpha. The brain in this case showed features of HIV associated early leucoencephalopathy. A PSS is an emissary vein of the posterior fossa that courses along the petrosquamosal junction, connecting the sigmoid or transverse sinus with the extracranial venous system.

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The composition and protein metabolism in the immature rabbit intervertebral disc. The BE (2)-M17 neuroblastoma cell line synthesizes and secretes corticotropin-releasing factor. Incubation with either compound alone was significantly less effective. Despite the early administration of appropriate and adequate treatment, the patient died 7 days after the onset of the infection. pIRES2-LIF-NT-3 was transfected into HEK293 cells and reverse transcription-polymerase chain reaction and Western blotting were used to test the co-expression of double genes.

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This review illustrates the pathophysiological and functional changes in left atrium in heart failure as well as their prognostic value. Possible ways of desactivation of singlet-excited state of chlorophyll a in the complexes with TCD and TNB were analysed.

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A simple instrument to define the Frankfurt horizontal plane for soft-tissue measurements of the face. Plasmodium falciparum malaria in a patient with delayed detectable parasitemia. Therefore, JLB is located within the intergenic sequence between rps19 and rpl22. The error-free sub-pathway is also used for bypass of spontaneous DNA damage and functions in cooperation with recombination pathways. Five components of apparent molecular weights 137,000, 121,000, 97,000, 67,000, and 57,000 have been shown to be exposed at the outer surface of the cell.

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However, deafness is not associated with the renal disease, and affected dogs do not have the large platelets that are occasionally seen in patients with autosomal Alport syndrome. Because the specific levels of blood pressure and cholesterol are of little clinical relevance when considered in isolation from other risk factors, terms such as hypertension or hypercholesterolaemia have limited value. The substances showed only weak antagonistic activity at both histamine receptors H1 and H2.

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A case in which preoperative diagnosis of megaduodenum due to stenosis caused by an incomplete pancreatic ring is presented. It cannot, however, be excluded that other brain regions are involved. Cardiac insufficiency: its definition and the mechanism of development It must remain open if the fibroelastosis of the left ventricle was congenital.

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The production of reproductive lethal cell lesions by freeze and thaw cycles has been studied by means of colony size spectrometry in tetraploid CHO-fibroblastoma protected with glycerine. Presentation of selected studies on the disease picture of multiple sclerosis After recording microvessels on videotape, consecutive frames from the videotape were digitized by a computer. Increased serum phospholipase A2 activity in Malawian children with falciparum malaria.

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In 5 patients, plasmapheresis was followed by a rapid rebound of complexes and antibody to pretreatment levels. In comparison of the reverse phase nystagmus, the first phase nystagmus has the shorter incubation and duration, but it has more power. A single cynocephalus animal has been found to have only normal I gamma-chains and I gamma C-chains (that is, glycine in residue 9, valine in 23, and isoleucine in 75). Stimulus duration thresholds for letters presented alone and for the middle letters of 3-letter words and nonwords were determined for stimuli presented at the fovea and at the periphery. Plant toxin abrin induced oxidative stress mediated neurodegenerative changes in mice.

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Fifty-five artificial bone defects were produced in six dentate jaw segments. PU.1, a member of the Ets family of transcription factors, is implicated in hematopoietic cell differentiation through its interactions with other transcriptional factors and cofactors. In these neurons, WIN-induced effects were antagonised by the non-selective cannabinoid receptor antagonist SR141716A and by the vanilloid receptor antagonist capsazepine, but not by the selective CB1 antagonist AM-251. ZAP75 is identical to the glycophosphatidylinositol (GPI)-anchored protein, GP2. In normal rats, the dopamine D3 receptor-selective ligand, 7-hydroxy-2-(di-n-propylamino)tetralin (7-OH-DPAT), produced biphasic effects on spontaneous locomotor activity, i.e.

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In case of cytological diagnosis, the diagnosis based on the detailed collection of the clinical information becomes necessary. A competition reaction is used to enable continuous measurements of the solution antigen concentration. Composite cerebral metastasis and oligodendroglioma: an exceptional form of mixed neoplasia. Meningiomas: correlation between MRI characteristics and operative findings including consistency. The results showed little change during the 24-48 month interval in mean scores for bleeding on probing, probing depth, and probing attachment level for all 3 groups of sites.

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We tested the hypothesis that a bispecific antibody with specificity for an adhesion molecule and for a tumor specific antigen binds preferentially to tumor cells which coexpress both antigens and hence selectively blocks adhesion. Partial characterization of a bone-derived chemotactic factor for tumor cells. Different sources of B73 and W23 were examined for NUMT variation within inbred lines. The polyclonal antibody, NH27, produced in the present study is useful in investigating the characterization of AR in androgen-dependent and -independent prostatic cancers.

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Stage I involved the creation of a vascularized pleuroperiosteal flap that was formed into a rigid tube around a Silastic stent. Ginkgo biloba extract in the treatment of arteriopathy of the lower extremities. The effect of in situ isolated perfusion of experimental renal tumors with cytotoxic agents in high concentration. The involvement of phosphatase and tensin homolog deleted on chromosome ten (PTEN) in the regulation of inflammation following coronary microembolization. Compared with repairs without PRP augmentation, the current PRP preparation and application methods for medium to large rotator cuff repairs significantly improved the quality, as evidenced by a decreased retear rate and increased CSA of the supraspinatus, but not the speed of healing.

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BMP4 activated Smad1/5 phosphorylation and upregulated ID2 and ID3 transcription, whereas noggin counteracted these increases. Although this is a relatively small series, the uniform good results in these patients with extensive disease suggest that ex vivo renal artery reconstruction is a safe and effective method of treatment. Rates of prophylactic preoperative antibiotic administration significantly increased after institution of a hospital policy advocating routine antibiotic prophylaxis prior to hysterectomy. This is the first time that it has been shown that, in the heart, angiotensin-(1-7) at pharmacological concentration activates NADPH oxidase, an enzyme thought to be involved in several angiotensin II effects.

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Delayed positive response to a flecainide test in a patient with suspected Brugada syndrome: a worrisome finding. The functional behaviour of the external and middle ear is well known, but the processes concerned with the transduction of mechanical motion into neural activity are still under investigation.