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Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology. d-Tubocurarine and succinylcholine caused significant histamine liberation while alcuronium, gallamine, and pancuronium did not appear to exert this effect. The pattern of immune response produced by tumor cells grown in vitro can be converted into the original type of response by repeated passaging of the tumor cells in vivo.

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Magnetic resonance imaging and magnetic resonance cholangiopancreatography findings compared with fecal elastase 1 measurement for the diagnosis of chronic pancreatitis. Influence of optimal and excluded oral hygiene on early formation of dental plaque on plastic films. Exposure to metallic catalyst dust: manufacturing and handling of catalysts in the chemical industry.

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Monoclonal antibodies raised against purified rat liver glucocorticoid receptors reacted with wild-type and nt- receptors but not with nti receptors. We evaluate the clinical outcome of temperature controlled high energy transurethral microwave thermotherapy for benign prostatic hyperplasia using heat shock strategy.

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Values were standardized by dividing the QTc by the standard deviation. Evidences have indicated that human capacity is partially influenced by genetic factors. These findings are explained by the fact that postdenervation changes in the skeletal muscles are not so heavy as in their direct lesion when, according to literature data, the satellite cells participate directly in the reparative process. The segregation of these mutations with disease alleles in 4 and 2 families, respectively, supports the hypothesis that multiple mutations at the phenylalanine hydroxylase locus explain the variable phenylalanine tolerance in patients with phenylalanine hydroxylase deficiency.

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Aortocoronary bypass operation as an emergency intervention after transluminal coronary angioplasty. Costal vascularization and pediculated costal grafts in mandibular reconstruction with intercostofacial microanastomosis

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Thus, this study investigated whether osteopontin (OPN) expression in VSMC was induced by MS, and identified the intracellular signaling pathways involved in OPN production. It has been proved that this therapy was relatively safe provided careful clinical surveillance were assured. Some examples are given of the conceptual role of spectroscopic time and distance scales with regard to the inference of domains in membranes from NMR or other spectroscopic studies, or the apparent failure to detect domains believed to be present.

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The most effective was bestatin-L-Arg X AcOH, with a Ki value of 0.21 X 10(-8) M with Leu-enkephalin as substrate. In order to determine the type of dihydrofolate reductase (DHFR) genes in these 22 trimethoprim-resistant isolates, colony hybridization with probes representing types I, II, III and V DHFR, were used.

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IGF-II was extracted from rat tissues by formic acid, and the extract was heated at an acidic pH and treated with acetone. There appeared to be a relation between severity of the disease and decreased proportion of Tm cells with concomitant increase of Tg cells. A cortisol level below 500 nmol/L after 30 min signifies impaired adrenocortical reserve. Effect of temperature on drug permeability through membrane consisting of Eudragit RS/PEG 400 blend polymers.

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Other results indicate that the protease activity displays a temporal pattern which completely differs from those of general parameters of development. Ovarian tumors are a group of neoplasms that have diverse spectrum of features according to the particular tumor entity. Chromatin of both hepatomas contains antigens which are not detected in liver chromatin. In 240 women with cancer the rate of detection of the disease by the non-medical staff was comparable to that of the medical staff, although the non-medical staff detected more cancers by mammography alone than did the medical staff.

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Intropunitiveness and parasuicide: prediction of interview response. Branhamella catarrhalis: antibiotic susceptibility and beta-lactamase production.

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The proteases and inhibitors regulate a variety of processes in tissue morphogenesis, differentiation, cell migration, and cancer cell invasiveness and metastasis. Some of the clinical problems most frequently seen in veterinary dentistry and their surgical solutions are discussed. Hydrogen peroxide (H(2)O(2))-induced oxidative stress is an etiological factor involved in several disorders. A zonal classification scheme was devised to assess whether an approaching vehicle requires additional time to safely clear the intersection based on the remaining phase time, type of vehicle, current speed, and current distance from the intersection.

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These studies indicate that both host and bacterial factors contribute to SP formation and maintenance, which correlate with Salmonella intracellular survival and the ability to cause lethal enteric (typhoid) fever. A retrospective review of a series of patients undergoing electrophysiologic studies and anterior anal sphincteroplasty was performed.

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The incubation with EGF (100 ng/ml, 0 degree C, 60 min) led to a decrease in density of intramembrane particles on the P surface of ventral cell membrane, while the number of coated pits increased there. There was no correlation between PR-ir and AGD, suggesting that these measures are influenced independently. Some indices of erythrocyte metabolism (EM): activity of lactate dehydrogenase (LDH), glucose-6-phosphate dehydrogenase (G-6-PD), glutathione reductase (GR) and common adenosinetriphosphatase (ATPase) activity were studied in 102 patients with acute viral hepatitis (AVH). A potent antipyretic effect was observed with intravenous injection of IM in LPS- and LP-induced fevers, but not in DNP-induced fever. This study sought to determine whether electrical stimulation of the amygdaloid central nucleus (ACe) produces cholinergically mediated neocortical arousal manifested in the suppression of frontal cortex delta wave (1-4 Hz) activity.

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The antimutagenic substance AV-153 appears to intercalate between the DNA strands at the site of a DNA nick in the vicinity of two pyrimidines. Sulpiride did not impair, but rather appeared to enhance trial-and-error learning overall. SDS-PAGE of homogeneous SoxYZ without reductant separated dimeric complexes of 25, 29, and 32kDa identified by the N-terminal amino acid sequences as SoxY-Y, SoxY-Z, and SoxZ-Z, and subunit cleavage by reduction suggested their linkage via protein disulfide bonds. Change of diagnoses at the fundus in the aera of pars plana vitrectomy

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General strategies for the prevention of influenza infection are expanded to include many infants and young children, and are projected to significantly reduce morbidity and mortality from this key LRI pathogen. Mitogen responsiveness of various immune tissues: heterogeneity of accessory cells and susceptibility to suppression by macrophages. Moreover, patients with extensive comorbid medical illnesses, for whom standard operative repair is contraindicated may be successfully treated using endovascular means. A proteomic approach was used to identify the differentially expressed proteins in the brain of rats following a global ischemic stroke.

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This differential response was observed both in the presence or in the absence of a protein synthesis inhibitor. GISSI 2: Subproject on indexes of recanalization and left ventricle function

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Degree of cryodestruction depended on the time of freezing of the tissue examined patterns. It enables policy makers to design and prioritize follow-up activities to more precisely identify barriers, an essential next step to improving IFA distribution through ANC. Conversely, the incubation of HMC with phospholipase C impaired, and with trypsin enhanced, the interiorization of the parasites. Picture archiving and communication system: the impact of filmless and distance radiology. The identification of oncogenes and their products may have relevance to the development of new therapeutic strategies in cancer.

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We recommend that health professionals caring for these women enquire about symptoms of vaginitis so that appropriate diagnosis and treatment can be initiated. We used tensor-based morphometry (TBM) to analyze longitudinal brain volume changes associated with intensive virtual reality (VR)-augmented lower limb training in nine traumatic iSCI patients.

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Some useful aspects of such a system are discussed, particularly those which make for easier biologist-user interaction and system extensibility. At 2 h after COM treatment of bone marrow cells the mitotic index and C-mitotic effect were highest, then both decreased from 6 to 18 h. The data of the course of anesthesia recorded on magnetic tape by routine are analysed for this purpose bya computer with the statistical program SPSS.

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This study shows the use of observation and focus groups to describe and identify violations in the medication administration process. One of the most common bariatric operations is the laparoscopic Roux-en-Y gastric bypass (LRYGBP) in which the gastric capacity is restricted and the absorption by the small intestine is reduced. The tumors consisted of tubular adenocarcinoma cells, and had infiltrative growth to the submucosa and muscularis propria. Failure to improve postsurgically after 1 week warrants reoperation. SAAQ allows fast and easy quantification of LV function and can track hemodynamic trends in the operating room setting.

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Fecal samples of eight of eight, eight of eight, three of eight, and two of eight calves were positive at 2, 7, 14, and 20 weeks, respectively. Deep surgical and accidental hypothermia cause elevations in serum enzyme levels, probably because of ultrastructural cell damage.

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Video-based sexually transmitted disease patient education: its impact on condom acquisition. Severe changes of the thread surface were induced by direct UV radiation without absorbing media. Interleukin-18, interleukin-18 binding protein and impaired production of interferon-gamma in chronic renal failure.

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Fine structural changes in mast cells are concurrent with histamine release and are independent of the presence of leukocytes. As a soluble molecule, LAG-3 activates antigen-presenting cells through MHC class II signalling, leading to increased antigen-specific T-cell responses in vivo. Serum nitrite-nitrate levels were measured as an index of nitric oxide generation. In addition, we analyse the SV-IV sequence by several publicly available disorder-oriented predictors. These regions can cooperate or compete with each other, depending on circumstances that are beginning to be identified quite clearly.

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In yeast, the V-ATPase is composed of 13 subunits consisting of a catalytic V1 domain of peripherally associated proteins and a proton-translocating V0 domain of integral membrane proteins. Calcium-evoked dendritic exocytosis (CEDE), demonstrated in cultured hippocampal neurons, is a novel mechanism that could play a role in synaptic plasticity. The patient died due to bleeding of the aneurysm 20 h after anticoagulation treatment with heparin. The major peak corresponded to a peptide less hydrophobic than synthetic porcine NPY.

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Clinical and laboratory autonomic examinations revealed decreased sweating in the distal extremities, decreased lacrimation and salivation, a decrease in the average urinary flow with residual urine and hypersensitive pupillary constriction to the instillation of methacholine. Cocrystal structures of these macrocyclic natural product inhibitors in a modified porcine carboxypeptidase B revealed their binding mode and provided the basis for the rational design of small molecule inhibitors with a previously unknown central urea motif. By immunohistochemistry, an increase in MCP-1 expression was observed in mononuclear, endothelial, Leydig and peritubular cells. Taking estrone sulphate seemed no more likely to increase risks of endometrial carcinoma than ingesting estradiol since the 2 preparations become identical during metabolism. This review postulates that optical reflectance spectroscopy and bioimpedance may allow for accurate identification of the relationship between needle tip and target nerve, currently a high priority deficit in PNB techniques.

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Reassembly of flagellar B (alpha beta) tubulin into singlet microtubules: consequences for cytoplasmic microtubule structure and assembly. This paper presents calculations of the shielded dipole potential in the interior of a pore piercing a lipid membrane that is at a potential V0 with respect to the aqueous solution. Immunohistochemical localization of inhibin in the retinal interphotoreceptor matrix. An unselected material of 177 patients with malignant tumours of the oral cavity is presented and classified according to the TNM system.

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Dynamic exercise caused significant increases in heart rate and S1 amplitude which were largely inhibited by beta-adrenergic blockade. These mutations alter PDE3A activity by uncovering cryptic sites for phosphorylation by PKA and PKC, leading to enzyme hyperactivation that abnormally lowers cAMP levels. During hemorrhage, hypertensive rabbits had an attenuation of hindlimb vasoconstriction, a reduction in the heart rate-mean arterial pressure relationship, and reduced ability to maintain blood pressure compared with normotensive rabbits. According to literature described earlier it has been suggested that welding fumes cause the lung function impairment, obstructive and restrictive lung disease, cough, dyspnea, rhinitis, asthma, pneumonitis, pneumoconiosis, carcinoma of the lungs. Learning about cognition risk with the radial-arm maze in the developmental neurotoxicology battery.

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In addition they all show anticipation correlating with the length of an unstable trinucleotide repeat. In the retina the immunoreaction was restricted to photoreceptor cells, which displayed immunostaining in their perikarya and outer and inner segments. Expression of WRKY41 is induced by inoculation with the incompatible pathogen P. On the other hand, when DPH was injected into the left ventricle of the heart, the mean effective dose was 1.7 mg/kg and the dose was significantly increased to 4.4 mg/kg when cerebral circulation was temporarily occluded.

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Glomeruli were isolated by a passive sieving technique according to the method of Misra and were incubated at 37 degrees C for 60 min in the presence (Group II: 10(-6) M, Group III: 10(-5) M) or absence (Group I: control) of alpha-hANP. The discovery of new druggable targets and pathways including those that are critical for multiple life cycle stages of the malaria parasite is a major goal for developing next-generation antimalarial drugs. This investigation consisted of two experiments in spinal cord hemisected young adult female Sprague-Dawley rats. Dose-dependent noradrenergic and serotonergic properties of venlafaxine in animal models indicative of antidepressant activity. State of Trp 62 in hen egg-white lysozyme bound with N-acetylchitooligosaccharides.

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At the individual level, both the microfilarial status (microfilaremic/nonmicrofilaremic) and the level of parasitemia showed a remarkable stability over time. In SCN-lesioned rats, administration of MA and GL caused no change in plasma glucose level, irrespective of the lighting condition. Cell surface expression and fusion by the varicella-zoster virus gH:gL glycoprotein complex: analysis by laser scanning confocal microscopy.

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Superficial suppurative thrombophlebitis in children, caused by anaerobic bacteria. These were found to be present in isolated guinea pig left atria studied in 0.9 and 1.8 mM Ca bathing solutions and were partially dependent upon adrenergic mechanisms (presumably secondary to norepinephrine release from sympathetic nerve endings) and partly independent of such mechanisms as demonstrated by propranolol induced beta-blockade and reserpine-induced catecholamine depletion. Oxytocin receptor gene sequences in owl monkeys and other primates show remarkable interspecific regulatory and protein coding variation. Seaweed hydrocolloid production: an update on enzyme assisted extraction and modification technologies.

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All women had undergone a standardized interview, clinical examination including Modified Oxford Scale (MOS) grading, urodynamic testing and four-dimensional translabial ultrasound (TLUS). Morphological examination of the Leydig cells showed an accumulation of lipid droplets in the cytoplasm of the testes exposed to 43 degrees C, indicating a disturbed steroidogenesis. Muscle oxygen tension, hemodynamics, and oxygen transport after extracorporeal circulation. Effects of acute non-selective beta-adrenergic blockade on plasma ammonia levels in exercising dogs.