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The efficacy of antineoplastic compounds can depend heavily on the genetic background of the cells exposed to the drugs. In 177 patients who had undergone locally curative surgery and had had an uneventful recovery, a postoperative follow-up program, including computed tomography (CT), was carried out. Future trends in biocompatibility aspects of hemodialysis and related therapies. To study the perspectives of nurses on (i) the process of decision-making regarding the placement of feeding gastrostomies, (ii) their role in the process, (iii) the impact this participation has on them personally and (iv) gastrostomy placement in general. Patients with nonradiographic axial SpA achieved a status of low disease activity more frequently than those with AS if outcome parameters that included the CRP level were used.

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DNA was collected from over 200 individuals in these families to establish their genetic risk status for FAP, either by direct mutation analysis, or by linkage analysis. The morphologic characteristics of the endothelial linings in these two specimens have been studied. That is a possibility for the release of membrane-bound and cytosolic enzymes without destruction of enterocytes. The effects of intranigral GABA and dynorphin A injections on striatal dopamine and GABA release: evidence that dopamine provides inhibitory regulation of striatal GABA neurons via D2 receptors.

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Effect of bile salt excess in the duodenal lumen on the enzymatic equipment of pancreatic tissue in the pig It might be that metformin leads to a slow-down in glucose absorption and as a consequence to a decrease of insulin secretion. But when RBCs hemifused to GPI-HA-expressing cells were osmotically swollen, some diaphragms were disrupted, and spread of both inner leaflet and aqueous dyes was observed. Newer targeted and immunotherapeutic agents and combinations currently are being translated into the neoadjuvant setting at an accelerated pace and carry significant clinical promise.

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OBJECTIVE: To alert pediatricians about the possibillity of childhood Idiopathic Pulmonary Hemosiderosis, in cases of anemia associated with chronic lung disease. Consistently, the analysis of transgenic plants verified BIK1 function on EIN3 repression. Human immunodeficiency virus infection and indeterminate western blot patterns. A missense mutation in KCTD17 causes autosomal dominant myoclonus-dystonia.

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Cultivation and differentiation of haemopoietic CFU-C cells in semisolid medium. Multivariate logistic regression models adjusted for age, sex, race/ethnicity, education, urban/rural residence, current DSM-IV Major Depression, and local county unemployment rates. The diagnostic process is complex and requires a multidisciplinary approach involving a pulmonologist, radiologist and pathologist.

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Clinical and immunological studies have consistently shown a relationship between atopic diathesis and idiopathic nephrotic syndrome (INS). A large number of them were isolated from the 10(-6) dilution and some species of Eubacteria and Clostridia could only be recovered from the 10(-3) or 10(-4) dilutions. Impaired absorption of chlorpromazine in rats given trihexyphenidyl. In an additional group of 8 young men, the dynamics of plasma ACTH and cortisol levels were studied during a 30 min sauna exposure (90 degrees C). Thermal asymmetric interlaced PCR: automatable amplification and sequencing of insert end fragments from P1 and YAC clones for chromosome walking.

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beta-Ep-LI release from anterior pituitary in vitro significantly decreased after the addition of TRH to medium. In addition, the mean diastolic blood pressure in the control group showed that the treatment provided was already satisfactory, and that there was little need for improvement. Carotid intima-media thickness, a marker of subclinical atherosclerosis, and particulate air pollution exposure: the meta-analytical evidence. How the general practitioners can help the district medical officer

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To explore a potential role for ARC in protecting muscle fibers from dystrophic breakdown, we have cloned and characterized murine ARC and studied its expression in normal and dystrophic mouse muscle. There has been a change in preference from open-sky techniques to the use of automated vitrectomy instruments. Immunohistological methods such as immunofluorescence and immunoperoxidase techniques can be applied without restrictions. No prognostic information was obtainable in observing the inflammatory response of nodes altered by radiation effects.

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Using the Vidas DD new assay, our study provides reference intervals for DD in the postpartum period. We are interested in identifying the ligand binding site of the human folate receptor (hFR). Detection of c-sis transcripts and synthesis of PDGF-like proteins by human osteosarcoma cells. In addition, Ahnak(-/-) mice displayed increased Doublecortin-immunoreactive neuroblasts compared with wild-type controls.

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Interleukin-2, a product of helper T cells, is essentially involved in the regulation of cell-mediated immunity. Combined detoxification and immunocorrective therapy in patients with peritonitis The effect of oxytocics stored at high temperatures on postpartum uterine activity. A system for culturing sheep thyroid cells in vitro is described.

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In this process, hepatic activated stellate cells are the key players. A case of genetic hemochromatosis presented with asymptomatic hepatomegaly. These results can be used to construct confidence intervals and to test statistical hypotheses. The aim of the present study was to assess the safety and efficacy of this new topical agent as a first line treatment in patients with chronic anal fissures. One of these proteins, with a molecular weight of 42.5 kd, co-migrated with rabbit muscle actin.

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The severity of urinary tract involvement determines to which group a given patient is assigned. A simple method for the continuous analysis of the phase relation between heart beat and respiration is described. In this study, we show that, besides interferon-gamma (IFN-gamma), lymph node (LN) cells draining the site of vaccination produce significant amounts of interleukin (IL)-4 and IL-10 in culture with parasite antigen. The presence of 99mTc activity in excised lymph nodes was documented by scintillation counting and autoradiography. Surviving cells show increased expression of HSP70, decreased cytosolic heavy neurofilament expression, and have various morphological abnormalities.

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The patient reported in this paper developed a severe, rapidly progressive vasculitis, apparently limited to muscle, after taking procainamide for 42 months, his myopathy remitting rapidly after withdrawal of the drug and a short course of treatment with azathioprine. Percutaneous upper urinary tract dynamics in equivocal obstruction. To delineate the anatomic architecture of the melolabial fold with surrounding structures and to elucidate potential implications for face-lift techniques. Antibody binding specifically to the virus polypeptides was then detected by application of 125I-labelled anti-immunoglobulin followed by autoradiography. Electrostatic nucleic acid nanoassembly enables hybridization chain reaction in living cells for ultrasensitive mRNA imaging.

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The homeless in the Chicago sample are unaffiliated persons living in extreme poverty, with high levels of physical and mental disability. Differential effects of 1,25-dihydroxyvitamin D3 on cytosolic calcium in two human cell lines (HL-60 and U-937).

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Modification of platelet function and vessel wall prostaglandin synthesis by pharmacologic intervention has attracted considerable attention. In SIV-infected macaques, MVA.HIVA DNA was undetectable by nested PCR 6 weeks after dosing. Studies of experimental allergic encephalomyelitis by using encephalitogenic T cell lines and clones in euthymic and athymic mice. Anatomo-pathological lesions, histopathological and ultrastructural examinations with the use of transmission and scanning microscope, serum cobalt-activated acylase (AA-Co) activity and urine arylsulphatase (ASA) activity were performed. It might be important for the well-known ability of alantone to increase both the peripheral blood circulation and microcirculation.

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These results suggest that HRR pathways responding to stalled replication forks or DSBs are genetically distinguishable. Therefore, we set out to determine individual risk and protective factors for RRV disease in a high incidence area and to assess the utility of the case-control design applied for this purpose to an arbovirus disease. The locus coeruleus in the rat: an immunohistochemical delineation.

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The number of the patients involved precluded analysis for significance. This study was performed to assess the inflammatogenic properties of nucleus pulposus in models previously screened for other substances. In this case, it was necessary to use high-resolution markers in order to establish the link between the infecting strain and 1 of the 10 strains handled. Cytoplasmic granules demonstrated strong complex carbohydrate staining, indicating a lack of granule maturation in HL60 cells. However, bleeding from the suture line was difficult to control.

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Preparing a quality control material for blood gases, pH and hemoglobinometry using stroma-free hemoglobin solution. Careful organization is the key to effective facilities planning. Eight minerals (Na, Mg, Ca, Mn, Fe, Zn, P and K) and six metals (Cr, Ni, Ag, Co, Cu and Pb) were studied.

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While offering hope for a healthier and more productive nation, New Medicine challenges us to come to terms with the cost, the complex social issues resulting from medical breakthroughs, and the limits to autonomy. The phenomenon of double ventricular responses during the tachycardia was demonstrated by extrastimulation from the proximal coronary sinus. The presence of an acute systemic bacterial or viral infection, coagulation abnormalities and pathologic tissue indicative of DIC, and skin lesions of the extremities progressing to dry gangrene and ultimately requiring bilateral amputation are the key clinical features of this syndrome.

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Coated and uncoated charcoal absorbed avidly calcium and glucose from the blood. The use of a one-step reverse dot blot hybridization with nonisotope DNA probe in this case was convenient and is recommended. Simulations are carried out for two different episodes and two different emission scenarios. Conformational studies of the synthetic precursor-specific region of preproparathyroid hormone. This study assessed the long-term clinical outcome of stenting chronic occlusions.

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However, the glucocorticoid injection had no effect on activities of digestive enzymes of the 21-day-old calves. An electrophysiological investigation of efferent synapses in the retina of the turtle was conducted by recording intracellularly from amacrine cells. This technique was recently used on three patients with hypersplenism associated with severe liver disease.

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The recurrence of the tumor mass was suppressed by 60Co irradiation, but a necrotic lesion developed over the right temporal scalp. A lexicon of home care and self-care technology terms was then created. Antibodies against mouse ovaries and their effect on fertilization in vitro and in vivo in the mouse.

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Comparative molecular model building using the known three-dimensional structures and the derived amino acid sequences of the lymphocyte enzymes has provided useful structural information, especially in predicting the conformations of the substrate binding sites. Critical to this classification system should be a sonographically based evaluation protocol that is systematic, evidence based, and reproducible with clearly defined end points.

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Furthermore, we identify MMP-3 as the major factor responsible for the effects of senescent fibroblasts on branching morphogenesis. albicans as a cause of median rhomboid glossitis is discussed in the light of these findings. Similarly to anti-asialo GM1-treated mice, LAK cells can be generated from these mice. The injection of these anti-Id mAb into H-2k mice resulted in the stimulation of self-class II-reactive T cell clones as determined by SMLR.

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In contrast, the GA85 positive control substitution reduced activation only at the promoter, where the FNR binding site is 41 bp upstream of the transcript start. Possible approaches to the pharmacological prevention of myocardial ischaemia. Upon further examination, the diagnosis of a ruptured popliteal cyst was considered, and was confirmed with arthrography. Sinusoidal modulated currents with a long pulse in the treatment of patients with the vertebrogenic lumbosacral radicular syndrome

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The spectral data suggested that this unfolding intermediate shared many structural characteristics with the native form of AK including its secondary structure, tertiary structure, as well as its quaternary structure. Survival time until death from heart disease or until the end of the follow up period in December 1992. Therefore, in the safety evaluation of compounds isolated from Tripterygium wilfordii, it warrants our attention to probe deeply into their precise dose/immuno-effect relationship. Three individuals with the disease-causing mutation did not fulfill clinical criteria for the disease. While the relative safety of ECT is sometimes used to justify its extensive use, ECT is abused in some cases, causing prolonged deficits in sensorium.

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Cystic duct leak after laparoscopic cholecystectomy despite preoperative sphincterotomy. When silicone gel breast implants became the subject of a public health controversy in the early 1990s, the most pressing concern was safety. The scaffold containing cells was transplanted into partially excised muscles of host female rats. In this study, we investigate how people with mild ID perceive their social networks and which network characteristics relate to satisfaction with the network and perceived QOL. Hyperandrogenism due to 3 beta-hydroxysteroid dehydrogenase deficiency with accessory adrenocortical tissue: a hormonal and metabolic evaluation.

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In order to investigate if they influence in some way the proliferation rate of the carcinoma cells, we developed a coculture model in which cells of well characterized breast epithelial cell lines were seeded and grown in microchamber slides along with fibroblasts derived from breast tumor biopsies. This test depends critically on details of the mutational process of microsatellites. In Experiment 2, females that engaged in nonsexual activities with conspecifics other than gonadally intact males had plasma levels of E2 and P4 equivalent to those of females that engaged in sexual behavior with males. However, computer programs reviewed are limited to the analysis of specific saccade parameters or partly depend on manual operations. Longevity and antioxidant enzymes, non-enzymatic antioxidants and oxidative stress in the vertebrate lung: a comparative study.

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Numerous small coronary arteries were occluded with platelet thrombi in all these sites, including especially the sinus node, AV node and His bundle. According to the selective-access hypothesis, prior semantic context biases people to access one meaning of an ambiguous word rather than another in lexical memory during recognition. In total, 30 publications written in English covering the relevant patient population and topics of interest. The incidence of hepatocellular adenomas was significantly increased in male mice treated with 3500 ppm TBP in diet. In vivo studies on Wistar rats indicated the absence of any significant toxicity caused by the intravenous administration of nanomedicine.

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DNA sequences have been obtained for embryonic chick feather and scale keratin genes. Memory impairment and its recovery in patients with intracranial hematoma after closed head injury Management of suspected tracheobronchial stenosis in ventilated neonates. We retrospectively included 84 patients with an ischemic stroke between November 2007 and March 2012, who underwent 3T MRI, were treated by thrombolysis, and had medical follow-up at 3 months.

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On reversal of treatment, the previously nonhealing epithelial defects healed when treated with topical epidermal growth factor eyedrops. The plasmatic arachidonate concentration sometimes reached values ten times higher than the maximal normal value of 5 micrograms/ml plasma registered in 157 controls. Two groups were studied: 44 healthy normotensive individuals (17 male, 27 female, age range 12-22 years) with a documented family history of hypertension and 33 individuals (14 male, 19 female, age range 11-21 years) without a family history of essential hypertension. A case is reported of a 26-year-old man, who after sustaining a fracture involving the nasal complex and left infra-orbital margin developed orbital cellulitis and a sub-periosteal abscess.

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4 out of 6 patients with LEV and 1 patient with LEI showed reduced levels of testosterone. Moreover, the same approach was used to successfully discriminate different variants of Trichomonas vaginalis virus, which was not possible by the visual comparison of the double stranded melting curves generated by MELTSIM. The toleration of rat thymocytes to xenogeneic erythrocytes: kinetics of induction and recovery. These results were further supported by the finding that specific chemical inhibition of flk-1 receptors caused disruption of the angiogenic response, whereas inhibition of the flt-1 receptors had no effect.

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Clinical and molecular characterization of a Brazilian cohort of campomelic dysplasia patients, and identification of seven new SOX9 mutations. B lymphocytes in blood remained within the normal range after chronic lymphatic drainage, but a large dose of X-ray markedly reduced their number.

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None of the patients became symptomatic from an enlarging tumor during their follow-up period. However, the effects of medium- and high-dose prednisone on urine output were less obvious. Pink teeth were noted during autopsy examination after twelve days in one corpse, and eight days following death in the second case. Growth inhibition in response to ACNU was seen in two cell lines (EA285, U251-MG), whereas two cell lines (YE2-02, T98) were resistant to ACNU.

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We present a case of angiotropic large-cell lymphoma and review the literature in order to define the neurologic features of this rare disorder. The need for critical care caregivers to complete their own grief work when a patient dies deserves special attention.

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Sprain or dislocation of the proximal interphalangeal joint may be a useful example of the counterintuitive aspects of recovery as the prognosis is excellent, but protectiveness in response to discomfort often hinders the stretching exercises that are a key component of the recovery process. II: A second generation system for off-line and on-line quantitative coronary angiography. The remainder were designated as having low probability because presentations were not linked to treatment or failed to meet criteria for the syndrome.