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It was found that TGF-alpha was predominantly localised in nuclei of oocytes. The surgical management of the rheumatoid spine: Has the evolution of surgical intervention changed outcomes? Expression of human papillomavirus type 16 E6-E7 open reading frame varies quantitatively in biopsy tissue from different grades of cervical intraepithelial neoplasia.

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In most of the test animals as well as in 10 of the 11 controls cytoplasmic vascuoles were found. The pulmonary lesions in small children with high eosinophilia and hyperimmunoglobulinemia E could be related to toxocariasis and for this reason they are eligible to undergo therapy with prolonged observation for several months, rather than start invasive malignancy investigations. Higher mean serum IgE levels were found in RA patients with extra-articular complications than in controls or RA patients with joint disease only, but the differences did not reach statistical significance. Assessing Airway Microbiota in Cystic Fibrosis: What More Should Be Done? These techniques have been used to efficiently facilitate gene therapy by fabrication of non-viral vectors with high cytocompatibility, large gene-carrying capacity, effective cell-membrane permeability, and in vivo gene-loading/releasing functionality.

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Patterns of cortical projection to hindlimb muscle motoneurone pools. Immunoperoxidase and hematoxylin/eosin stainings of the tympanic allografts were also attempted to make a pathological correlation. Quality of acute episodic care in investor-owned ambulatory health centers. Clinical signs included diarrhoea and anorexia and were apparent for a week before death.

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A model hypocholinergic syndrome produced by a false choline analog, N-aminodeanol. The frequency distribution of isoantibody titres in serum samples with different Hp-type were compared. The value of this method of enucleation in diminishing tumor deaths remains unknown. Cold acclimation induces zonal heterogeneity in gluconeogenic responses to glucagon in rat liver lobule.

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Interferon-gamma and retinoic acid downregulated PU.1 expression in marrow macrophages. Heterozygous inactivating GCK mutations cause hyperglycemia, whereas activating mutations cause hypoglycemia. A previous report that the leukocyte count was related to mortality from cancer was evaluated in two large groups of multiphasic health examinees in the San Francisco Bay area, California--a cohort of about 25,000 persons followed up for mortality and a cohort of about 160,000 persons followed up for cancer incidence between 1964 and 1980. All children, 9-11 years of age, underwent a battery of neuropsychological tests and the parents completed behavioural rating questionnaires.

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Extensive tumor infiltration of the chest wall prevented any further surgery. A total of 44 breast tumor tissues were sampled by biopsy before treatment with docetaxel, and the response to therapy was clinically evaluated by the degree of reduction in tumor size. Pitchers demonstrated 9 degrees more external shoulder rotation with the arm abducted, 5 degrees more forearm pronation, and 9 degrees less shoulder extension on the dominant side compared with the dominant side of position players.

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Twice-weekly administration of carboplatin concomitant to post-operative radiotherapy did not improve local control or overall survival rates in this population of patients with node-positive head and neck cancers. Two patients with chlamydial pneumonia of infancy are described. There were 127 assessable patients entered onto this clinical trial. Studies on laser-assisted Penning ionization by the optogalvanic effect in Ne/Eu hollow cathode discharge. None of these methods fulfils all the criteria for the requirements of an ideal device and some are too complicated, uncomfortable or cumbersome for widespread use.

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The HLA-ABC- and -DR-antigens of patients with carcinoma of the larynx were determined. Detection of pancreatic steatorrhea by oral pancreatic function tests. Continuous respiratory support in quadriplegic children by bilateral phrenic nerve stimulation.

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The most active drugs found in vitro were teniposide, actinomycin D, bleomycin, hydroxyurea, mitoguanazone dihydrochloride, mitomycin C and L-alanosine. Human beta- and some alpha-interferons have been obtained by genetic engineering in E.coli.

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Properties of a kappa-opioid receptor expressed in CHO cells: interaction with multiple G-proteins is not specific for any individual G alpha subunit and is similar to that of other opioid receptors. A water-soluble extract of Actinomyces viscosus (AVS) was tested for its capacity to induce DNA synthesis in lymphocytes from man, monkeys, mice and guinea pigs. These results contribute to the understanding of the natural history of coronary artery disease and are also of historical interest.

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Nanostructures of polyaniline (PAni) and polypyrrole (PPy) with controlled morphologies have been synthesized on atomically flat surfaces using adsorbed surfactant molecules as templates. Clearance of 99mTc-MAG-3 also decreased from 366 (18) to 315 (17) ml/min in patients receiving methotrexate alone and further to 295 (17) ml/min during treatment with aspirin and methotrexate. Among men, four of the eleven events tested were associated with higher alcohol consumption but only as interaction effects. In the current study we used zebrafish larvae in order to determine the effects of two of the most widely used organophosphates, chlorpyrifos and malathion, on zebrafish behavior and AChE activity.

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Stronger and more vigorous interaction among the subsystems is needed. There is some danger in using them for efficacy trials because antihistamines are only partially effective treatment for hay fever and the challenge administered could easily overcome the degree of protection. Inhibitory activity was not specifically related to primary affective disorders. In contrast, the elimination of cholate and its metabolites is not increased. However, in contrast to the TNP-ABC where treatment of the B cells with anti-LFA-1 blocked T/B conjugate formation, pretreatment of the TNP-MABC with anti-LFA-1 had no effect.

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A 12-month angiographic and optical coherence tomography follow-up after bioresorbable vascular scaffold implantation in patients with ST-segment elevation myocardial infarction. A precipitated mixture of 27 and 130 kDa proteins was almost as toxic as solubilized crystals. Fertility issues should be discussed with young women before the start of any anticancer treatment. The covering of epithelial defects in the oral cavity presents special problems in preprosthetic surgery, since special requisites for function and quality of mucosal grafts must be satisfied. Study of excited membrane refractory period length in patients using biological feedback to an interference current device

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Changes in medium composition and the nature of growth limitation caused variations in both d mu and R. Six patients were treated with concurrent PTBD and PVE under general anesthesia. An estimate of the total driving force from red blood cell to mitochondria was greater in anemia.

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Nevertheless, the high levels of loosely-bound iron found after Fe-dextran treatment in plasma and in exudate contribute to the increase in oxidative stress. Leucine oxidation in diabetes and starvation: effects of ketone bodies on branched-chain amino acid oxidation in vitro.

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TVCNB in this case was less invasive and easier to perform than other exploratory procedures, and has a low risk of iatrogenic intraperitoneal dissemination even if the tumor is malignant. We also show that a peptide model of alpha-helix 1, which contains Asp 14 and Arg 17, forms a reasonably stable, monomeric helix in solution and responds to alanine mutations at positions 14 and 17 in the fashion expected from the intact protein studies. At the end of 2 courses, a partial response of the neck metastasis was achieved. Blast transformation of B-lymphocytes but not of thymocytes is significantly stimulated by S8CT.

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To validate the accuracy of catheter endocardial mapping to localize the origin of ventricular tachycardia (VT), we compared cathether endocardial mapping with intraoperative epicardial and endocardial mapping of 24 morphologically distinct VTs in 18 patients undergoing surgery. Preparation of branched hexasaccharides by the action of a viral lyase on Klebsiella K14 polysaccharide.

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The court-probated alcoholic and outpatient treatment attrition. Hyponatremia in acute heart failure syndromes: a potential therapeutic target. Molecular evidence for novel planctomycete diversity in a municipal wastewater treatment plant. This is the first study showing that progesterone regulates the expression of endothelin1 and endothelin receptor A in the fallopian tube. Energy metabolism of adult Haemonchus contortus in vitro: a comparison of benzimidazole-susceptible and -resistant strains.

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The devices responded quickly to temperature changes despite being embedded in different thickness of silicone elastomer. Conversely, intra-CeA or intra-LC infusions of CNQX (2.5 microg/0.5 microl) significantly attenuated naloxone-precipitated withdrawal, an effect similar to the attenuation previously observed after intra-LC clonidine infusions. Ehrlich ascites carcinoma: synchronised ultradian rhythms in certain cell parameters. Relative and absolute deficiency of bone marrow endogenous colony stimulating activity in acute myeloid leukemia: relation to response to chemotherapy. Pulmonary circulation disorder in patients with chronic obstructive pulmonary disease

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Chitosan-coated plastic films containing 0.001 g/cm(2) of SL have a potential to be used on ham steaks to control L. Testosterone deficiency is associated with sickle cell disease (SCD), but its underlying mechanism is not known. Predominantly Cone-System Dysfunction as Rare Form of Retinal Degeneration in Patients With Molecularly Confirmed Bardet-Biedl Syndrome. (2) Bilateral peduncular lesions blocked clonic type C muscular convulsions and significantly decreased phasic clonic ETCD EMG MUA at the same body regions.

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Bulimic symptomatology and personality factors in a nonclinical sample: a replication. Preoperative cholangiography should be performed to evaluate the anatomy of the left hepatic duct to avoid injuring B4. The vast majority of benign serous tumors may not be bona fide epithelial neoplasms, but rather, may represent cystically dilated glandular inclusions (cystadenomas) and fibromas with epithelial inclusions (cystadenofibromas). The effect of miR-188-5p on HCC progression was studied in vitro and in vivo.

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Human plasma post-heparin lipolytic activity was reduced when collected in tubes containing lithium heparin as compared with samples collected in lithium sequestrene. This article reviews the evidence that congestive heart failure is accompanied by an increased plasma norepinephrine concentration and that this is due not only to a reduced tissue clearance of the substance but also to a marked increase in sympathetic nerve activity. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and endothelial nitric oxide synthase (eNOS) mRNA expressions were analyzed using real-time polymerase chain reaction (RT-PCR).

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The CAF-derived regulators and extracellular matrix proteins can support cancer progression by providing a protective microenvironment for the cancer cells via reduction of chemotherapy sensitivity. The abnormal mammogram radiographic findings, diagnostic options, pathology, and stage of cancer diagnosis.

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The major barriers for thrombolytic therapy for patients with AIS in this setting were delays in the provision of in-hospital services, like initial patient assessment, CT scans or laboratory studies. It involves the control of pronation in a selective type of flatfoot deformity in which the predominant pathology is seen within the subtalar joint. Helicobacter pylori eradication--understandable caution but no excuse for inertia. RMR, PFTs, strength, flexibility, circumference, and skinfold measurements were also carried out.

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Heparin, streptokinase, and tolazoline, used separately or in combination, can augment, prolong, or reactivate transient, covert bleeding, thereby facilitating angiographic identification and localization of the lesion. The corrective effect on scoliotic curves by sagittal changes of the spine in bracing is demonstrated by roentgenograms.

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X-ray crystal structure and molecular dynamics simulation of bovine pancreas phospholipase A2-n-dodecylphosphorylcholine complex. Characterization of nucleosome unwrapping within chromatin fibers using magnetic tweezers.

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These observations, as well as the growth properties of the mutant cells as a function of temperature and exogenous asparagine concentrations, are consistent with their decreased ability to aminoacylate tRNAAsn in vivo. Chronic Rhinosinusitis (CRS), one of the commonest chronic inflammatory disorders, is encountered daily in all healthcare settings. Cytochrome c oxidase and the polyanions increased the apparent pKa of alkaline transition of cytochrome c by an order of magnitude. Although the proportion of females represented in addictions research was found to have increased over earlier historical periods, studies using only male subjects were still common in 1990.

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Molecular mechanisms of skeletal muscle insulin resistance in type 2 diabetes. According to the authors, the inhibitory effect of these preparations is due to the cyto-destructive action of antibodies and complement on the infected cells. Total hospital stay, intensive care unit stay, postoperative bleeding, inotrope requirement and ventilatory support postoperatively was significantly less in group A. Moricrasa and its fractions were used for lysis of cicatricial tissue under in vitro conditions.

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When mice received a primary injection of the same amount of LPS incorporated into P. Antibody-induced suppression of Ig synthesis was attributed to interference with differentiation of B lymphocytes to the secretory stage. Antigenicity of passively acquired major histocompatibility antigens on T cells. ECS and CO2 anesthesia between tasting and illness: effects on taste aversion learning.

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This increase in CXCR4 levels on CML progenitor cells was likewise found in samples from CML patients treated with imatinib or IFN-alpha. Obsessive-compulsive disorder (OCD) is often refractory to treatment. In our present study, the clinical significance of urinary enzymes and BMG was not well evaluated, because urinary excretion of these indicators following ESWL were transient and mild.

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It has been demonstrated that in the cellular proteins of Streptomyces hygroscopicus JA 6599 and Streptomyces noursei JA 3890 b, the producers of the antibiotics turimycin and nourseothricin, respectively, phosphorylated proteins are present. The functional activity and antigenic expression of the fifth component of complement (C5) in concentrated bronchoalveolar lavage fluids (BALF) and serum samples obtained from 13 nonsmoking and 13 smoking baboons was quantified by specific hemolytic titration and radioimmunoassays. Species-specific and organ-specific characteristics of the total activity and the isoenzyme patterns of the four amphibian species are compared with those of rat and mouse. A modification of the skin reaction of the delayed type in guinea pigs Anecdotally, use of amphetamine appears to be high within some American Indian/Alaska Native tribes and has become a serious concern for most American Indian/Alaska Native communities.

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Three complete responses and three partial responses were obtained in six evaluable patients. Resistance of cancer to chemotherapy remains challenging to both scientists and physicians. Contribution of ultrasonic endoscopy in the topographic diagnosis of insulinoma.

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Proceedings of the XIX international conference of the International Society for Chronobiology. The dynamics of vacuole formation, of their changes and amount were followed depending on the time of exposition of these substances.

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NP-O-Succinimide-induced cutaneous sensitivity (CS) responses can be adoptively transferred by NP-primed lymphoid cells into naive K-, I-, or D-compatible recipients. Our results identify DYRK1A as a physiologically relevant regulator of Treg cell differentiation and suggest a broader role for other DYRK family members in immune homeostasis. Perinatal and postnatal patterns of plasma sex steroid-binding protein and testosterone in relation to puberty in the male little brown bat. These latter species all displayed five labelled bands in the range 24 to 41 kDa.

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Changes in cranio-facial morphology of individuals with hypodontia between the ages of 9 and 16. Childhood Ki-1 lymphoma presenting with skin lesions and peripheral lymphadenopathy. The ideology and structures of apartheid created a context of impoverishment and structural violence to which children were exposed. Residual concentrations of salinomycin were measured in the tissues of broilers following feeding of medicated feed containing 60 mg/kg salinomycin. The system had demonstrated a near-constant transfer efficiency for an operating range of 2cm-12cm.

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Dense pigmentation of the posterior lens capsule associated with the pigment dispersion syndrome. Macrophages have recently been shown to play a key role in promoting of recovery after some diseases as well as in aggravation of inflammatory responses, all the functions being resulted from microenvironmental conditions and therefore phenotypes acquired by macrophages in these conditions. Clinicians should be aware of the high prevalence of vestibular dysfunction in patients with EVA. Retrospective case series of all patients managed surgically for a diagnosis of PAES at the San Antonio Military Medical Center from 2005 to 2013.

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The contrasting aversive stimulus properties of beta-phenylethylamine and of amphetamine are described. The author suggests a new method for the assessment of the bactericidal activity of local tissues in the treatment of bone fractures or after effects thereof by the transosseous osteosynthesis methods. For the proteomics profiling, two complementary proteomics techniques MALDI-MS/MS and LC-ESI-MS/MS were employed. The clinical and histological features of ten pigmented keratoses arising on the face are described. SCNs with reactivity shown only on part or whole of neurites and cell membrane while the cell body is negative (to be considered as the result of GABA uptake).(ABSTRACT TRUNCATED AT 250 WORDS)

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In vitro, rosaramicin was highly active against Chlamydia trachomatis when added to the culture system 1 or 48 h after inoculation with the chlamydia. The desirable attributes of peracetic acid for wastewater disinfection are the ease of implementing treatment (without the need for expensive capital investment), broad spectrum of activity even in the presence of heterogeneous organic matter, absence of persistent toxic or mutagenic residuals or by-products, no quenching requirement (i.e., no dechlorination), small dependence on pH, short contact time, and effectiveness for primary and secondary effluents. Frequency discrimination: assessing global-level and element-level units in memory. The effects and mechanism of action of Bay k 8644 have been examined in the anaesthetised dog, on the isolated perfused guinea-pig heart, and on the isolated rabbit aortic strip.

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Material mixtures offer prospective possibilities for synthesizing coating materials with tailored optical constants. This outer epidermal wall is considered as the growth-limiting boundary between plant and environment. The expression of these enzymes is regulated at the transcriptional level by a variety of growth factors and oncogenes.