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Position-reading and the emergence of sense organ precursors in Drosophila. Of the three, only one had clinical signs and symptoms consistent with TB and positive AFB sputum smears. Mutants of Pseudomonas aeruginosa are described which are markedly deficient in alkaline protease production.

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Although these tumors are benign, we recommend an early aggressive surgical approach to control the infiltrative nature of their growth and to improve facial appearance. Study of the association of HLA class I antigens with kala-azar. Organisms usually show intercorrelations between all or some of their components leading to phenotypic integration, which may have deep consequences on the evolution of phenotypes. The time course of the vascular response to hCG is quite different from the response in testosterone secretion by the testis. Computed tomographic values derived from scanning stratified sub-slice thickness objects were shown theoretically and experimentally to have a non-linear dependency on relative fractional content and a surprisingly large dependency on spatial extent of the stratified substances.

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Lysophosphatidic acid (LPA) in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1. Tumor xenograft model was used to characterize the biological functions of Restin in vivo. Women reported higher levels of global social support than their twin brothers. Lifetime PTSD was strongly associated with bodily pain in this rural sample of American Indians. Increased expression of the PRb-1 gene was also observed in resistant compared with near-isogenic susceptible barley plants following treatment with ethylene, salicylic acid, methyl jasmonate and 2,6-dichloro-isonicotinic acid.

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It is the first clinical study supporting the concept that hypoxia is a key driver of infiltrative tumor growth in glioblastoma patients. The soy isoflavone genistein induces a late but sustained activation of the endothelial nitric oxide-synthase system in vitro. If insomnia extends beyond the acute or postacute withdrawal period, trazodone may be an effective treatment.

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The focus groups identified large barriers to value transmission, stemming from adolescent acculturation to the United States. The albumin binding was found to be a time-dependent, saturable, and displaceable process which obeyed simple kinetic equations. Surgical treatment of dysthyroid eyelid retraction and orbital fat hernia. Ultrastructural characteristics of the cultured Schwann cells are compared to the Schwann cells of 3 day-old and adult rat sciatic nerve. To determine whether the amplicon contained additional coding regions, Southern blots of cosmid clones containing amplicon DNA were probed separately with reverse-transcribed mRNA from methotrexate-sensitive and methotrexate-resistant cells.

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The nuclear bag1 intrafusal fiber mediates the dynamic (velocity) sensitivity, whereas the nuclear bag2 and nuclear chain fibers mediate the static (length) sensitivity of muscle spindles to stretch. Natural history of unruptured cerebral aneurysms is still a matter of discussion. In contrast, haptoglobin subtypes displayed no significant effect on immunoglobulin levels.

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The cellular and molecular mechanisms that mediate these phenomena are under investigation. Several cases of severe hyperuricemia and at least one episode of acute arthritis in patients receiving PZA prompted us to study PZA prospectively with regard to these side effects. Increasing the LPS stimulus more than 100-fold over the amount needed to activate the cells did not substantially increase their resistance to the negative regulatory effect of PGE2. Dysplasticity, metaplasticity, and schizophrenia: Implications for risk, illness, and novel interventions. In a 3-year review of 218 teeth with retrograde root filling with amalgam orCavit, the results obtained with the former proved significantly better than those obtained with the latter.

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The impact of psychosocial work environment factors on the risk of disability pension in Denmark. The vast majority of otherwise healthy adults with anatomically and functionally normal urinary tracts experience few untoward long-term consequences from symptomatic or asymptomatic UTIs. However, they differed in their specific activities and isoelectric points. The astroglial cells were identified using an antibody raised against the astroglial-specific protein glial fibrillary acidic protein (GFAP). Results of a clinical and electroencephalographic cross-sectional study

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Monoclonal antibodies to human sarcoma and connective tissue differentiation antigens. These findings provide direct evidence that left prefrontal and temporal regions jointly promote memory formation for verbalizable events. The nanocarrier will also protect CA from degradation and sustain its release.

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HLA-B27, Klebsiella and ankylosing spondylitis: biological and chemical studies. Detection of corticotropin-releasing hormone receptors R1 and R2 (CRH-R1, CRH-R2) using fluorescence immunohistochemistry in the myometrium of women delivering preterm or at term. Balloon angioplasty is successfully applied to a wide range of aortic, pulmonary artery, and venous stenoses. Slight renal impairment tended to increase with the progress of hypertension, as evidenced by a slight but significant increase in the levels of blood urea nitrogen (BUN) and serum creatinine, and by a progressive decrease in creatinine clearance. The report includes 3 illustrative cases operated on in the Department.

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Protective effect of beta-carotene and canthaxanthin against UV reactions of the skin A report of a new case with associated carcinoma of the uterine cervix and angioid streaks of the eyes.

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Their structures were determined by spectroscopic analysis, chemical modifications, CD, and single-crystal X-ray analysis (1 and 4) as excolide A (1), 11-epi-excolide A (2), 11,13-di-epi-excolide A (3), and excolide B (4). One of the barriers to applying these growing volumes of information in fields such as risk assessment is the lack of informatics tools to organize, curate, and evaluate thousands of journal publications and hundreds of databases to provide new insights on relationships among exposure, hazard, and disease burden. Laser Doppler flowmetry (Oculix) was used to measure relative optic nerve blood volume (Vol), velocity (Vel) and flow in the superior temporal (ST) and inferior temporal (IT) neuroretinal rim of the optic nerve.

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CF particles were deposited in clusters at intervals of 100-150 nm on the interstitial side of the BL facing the connective tissue, while the cellular side facing the Schwann cell plasmalemma showed only an occasional deposition of CF particles. CMS extends its mandated quality data campaign to include home care. Biosynthesis of the labelled rifamycin B in the presence of different 14C- and 3H-precursors

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The addition of ovine prolactin (NIH-P-S-10) to the perfusate in a concentration of 50 ng/ml produced rapid increases in both the amplitude and rate of contraction in 33 adult male hearts studied in winter. Andrew Feinberg shares his views on the field of cancer epigenetics, from its beginnings to the most exciting recent findings. This parasitic disease is observed in cats worldwide but has a fairly variable incidence and is not always easy to diagnose. Ultrasonic vocalizations in immature gerbils: emission rate and structural changes after neonatal exposure to androgen. Turning (Ir gene) low responders into high responders by antibody manipulation of the developing immune system.

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Serum high-density lipoprotein cholesterol (HDL-C) has been determined in 85 patients with peripheral vascular disease (PVD) and in 72 healthy control subjects. To investigate the effect of extracapsular lensectomy with posterior capsulotomy, 20,000- and 70,000-dalton dextran was injected into the vitreous of rabbits.

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As he points out, several of these skin conditions precede the actual clinical and laboratory diagnosis of diabetes by several months to several years. It is very likely that the drug problems in African countries will worsen in future unless more effective measures are implemented to arrest the current situation. SP-A levels are increased in the lungs of HIV-infected individuals. Activity of fleroxacin alone and in combination with clindamycin or metronidazole in experimental intra-abdominal abscesses.

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However, acetaldehyde induced both single-strand (even at the lowest concentration of 1.56 mM) and double-strand breaks (only at the highest concentration of 100 mM). In the CNGA2-E325K mutant, PsTx affinity was reduced by approximately 5-fold to 120 nM. Endoscopic drainage of cystic dystrophy of the duodenal wall: report of three cases

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Multi-state survival analysis in renal transplantation recipients. The catecholamines generated from isolated notochords tend to diffuse into the culture medium, probably due to a deficiency in the vesicular storage system usually found in the catecholamine-synthesizing cells. However, regarding organ transplant in different communities, these advances raise major ethical, policy, and religious issues.

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We found that significantly more serious sprains and torn ligaments occurred on grass than occurred on Tartan Turf. The liver was the most common organ involved, followed by chest, kidney, peritoneum, spleen and retroperitoneum. In Experiment 1, level-of-processing manipulations were used to examine pre-cue representations of items in directed forgetting. The data are consistent with the view that testosterone, but not the adrenal androgens DHA and DHAS, contributed to the behavioral development of the males. The structure of the homeodomain and its functional implications.

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The growth of cells is determined by the balance between growth-stimulatory and growth-inhibitory signals. This article reviews adjuvant immunotherapeutic strategies currently in trials or under development for SCCHN patients, including vaccination or cytokine immunostimulation. Acid secretion during the fasted state, the cause of which is not known, seems to be one of the main factors in disturbing the regularity of the interdigestive motor pattern.

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Acetylcholine receptor antibodies in the diagnosis of human and experimental myasthenia gravis. Talpid2 mutant of the chicken with perturbed cartilage development has an altered precartilage-specific chromatin protein. The calculated profiles of wall concentration and mural flux were significantly different from those which would have obtained if the shear had been uniform. Pure macrophages themselves, however, were not producing IFN when treated by MAS. Curettage of the uterine cavity one month later failed to reveal any retained placental tissue or other pathology.

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An analysis of the same viruses with a panel of monoclonal antibodies was much less informative. Purification of an MCM-containing complex as a component of the DNA replication licensing system. Inorganic polyphosphate as an integral part of alkaline phosphatase preparations. Four multiplex families affected with adult polycystic kidney disease were investigated for segregation of the disease with haplotypes bearing HLA-A and B antigens and Bf allotypes. These data hint at the involvement of APP in the major morphogenetic events taking place in rat brain during the first three postnatal weeks.

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The c-Jun N-terminal kinase (JNK) pathway can play paradoxical roles as either a pro-survival or a pro-cell death pathway depending on type of stress and cell type. By studying the in situ expression of the cell cycle genes cyc2, H4, and cdc2 in pea and alfalfa root cortical cells after inoculation with Rhizobium or purified Nod factors, we show that the susceptibility of inner cortical cells to Rhizobium is not conferred by an arrest at the G2 phase and that the majority of the dividing cells are arrested at the G0/G1 phase. Population-based study of demographic, medical, ocular, familial, and other factors possibly related to open-angle glaucoma. The aim of this study was to assess the role of bone subtracted computed tomographic angiography (BSCTA), a novel and noninvasive method for determining and characterizing intracranial aneurysms. Although its importance significantly increased when it has been demonstrated that house dust contains significant silverfish levels even in houses where the inhabitants were unaware of its presence, no silverfish extract for diagnosis of allergic diseases is commercially available yet.

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Magnetic resonance imaging: technical aspects and recent developments megaterium H, like other microbial and tissue antigens having no similarity with tumour cells, did not produce such an effect. An intriguing development in the G-protein signaling field has been the finding that not only the Galpha subunit, but also Gbetagamma subunits, affect a number of downstream target molecules.

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These observations indicate that Dcir is a negative regulator of DC expansion and has a crucial role in maintaining the homeostasis of the immune system. These observations suggest a possible role for streptolysin O as a pathogenic factor in streptococcal infections.

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The strong correlation between interictal regional slowing and lateral temporal hypometabolism suggests in turn that the second may delineate a field of reduced neuronal inhibition which can receive interictal and ictal propagation. The immunomodulatory molecule cyclosporine was found to cause an early acceleration of the capping of mouse B-cell membrane immunoglobulin. Pattern and management of substance abuse at Aro Neuro-Psychiatric Hospital (1980-1982): a study in advance of the establishment of a special unit.

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Effect of focused ultrasound on the electroreceptor system of skates and certain fish and amphibian tissues The challenges that are hampering the further development of AFM for studies of cellular activities are aslo discussed.

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In 5 euthyroid patients the TRH test revealed a low thyroid reserve. These assignments have been used to study the pH dependence of the structure of the protein and binding of analogues of redox-active reagents to the protein. Alcohol expectancy and stress: methodological concerns with the expectancy design. Although these people could not distinguish old from new items even at short delays (most could not even remember having seen any sentences), their retention as assessed by reading time was similar to that of the other groups. The importance of pipelining the data flow and the ordering of the operations performed in a specific application of such a system are also noted.

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After reduction with dithiothreitol, all the molecules migrated to the position of molecular weight 33,000. We demonstrated no significant differences in unplanned admission rates, unplanned contact with health care services, or post-operative complications in the first 24 h after discharge between ASA III and ASA I or II patients. Since this coral tissue, once bleached to whiteness, contains no 70-kD heat shock protein, we conclude that the process of coral bleaching might include, among other metabolic alterations, a failed heat shock response. Treatment of Fura-2 loaded HEL cells, a human megakaryocyte-like cell line, with P2-purinoceptor nucleotide ligands (ADP, ATP, UTP, 2-methylthio-ATP) evoked a rise in cytosolic calcium.

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Brain activation in the vermis and posterior cingulate/precuneus appears to be a biological marker of recovery potential from PTSD. Nifedipine inhibits granulocyte activation during cardiopulmonary bypass. Three toxins (CM-8, CM-11, and CM-13a) were purified from the venom of Naja haje annulifera by gel filtration on Sephadex G-50 and by ion-exchange chromatography on CM-cellulose.

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The main beliefs on behaviour related to commencement of antenatal care, daily activities, quarrels, bad rituals, infidelity and the use of condoms during pregnancy. However, their reach is often limited because of a variety of barriers (e.g., travel, physical burden, cost, time). SMA syndrome can occur much later than previously reported and with potentially life-threatening symptoms following scoliosis correction. Such a behavioral strategy could evolve if pathogen resistance were heritable. Goals of care are important for older adults with severe illness and their families, and are infrequently addressed by health professionals.

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The correlation between history, rhinoscopy and rhinomanometric results was tested on 110 subjects using a detailed questionnaire and evaluation system. Ligation of CD27 on B cells has been shown to inhibit terminal differentiation of activated murine B cells into plasma cells. No endothelial changes were seen after infusion of the grafts with cold blood. The ADAMTS13 dependent degradation of VWF to its proteolytic fragments can be visualized as a characteristic so-called triplet structure of individual VWF oligomers by multimer analysis.

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Depending on chemical structure, exogenous fatty acids containing less than 6 to 9 carbon atoms or more than 15 to 18 carbon atoms were not substrates for the chain elongation system. A multicentre comparative trial of sodium valproate and carbamazepine in adult onset epilepsy. Abdominal actinomycosis is an extremely rare infection that can mimic multiple disease processes and requires accurate diagnosis for successful therapy. Single-dose antibiotic therapy for urinary tract infections and type II error. Pressor and tachycardic actions at the early phase were mostly abolished by either hexamethonium or phentolamine with the blockade of sympathetic nervous system (SNS), and slightly diminished by the V1-vasopressin blocker.

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Differential expression of CCR3 and CXCR3 by human lung and bone marrow-derived mast cells: implications for tissue mast cell migration. This device permits precision alignment of targets within the Rayleigh range of tight focusing geometries for a wide variety of target surface morphologies.

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Based on sodium dodecyl sulfate-urea polyacrylamide gel electrophoresis and gel chromatography on Sephadex G-25, peak 1 appeared either as a diffuse band and as a single peak, respectively. An experience with 32 consecutive patients with pericardial effusions is reviewed and presented. Nippostrongylus brasiliensis infection leads to the development of emphysema associated with the induction of alternatively activated macrophages. Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease.

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Early studies assigned part of this regulation to a soluble product, initially designated T cell-replacing factor or TRF. On the other hand, the retrograde axonal transport of HRP in the spinal muscle, characterized by the tonic muscle, was distinctly reduced in the scoliotic group, but it did not correlate with an angle of scoliotic curvature and the duration of scoliotic deformity.

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Protein-Derived Acetaminophen-Cysteine Can Be Detected After Repeated Supratherapeutic Ingestion of Acetaminophen in the Absence of Hepatotoxicity. Why are treatment programs aimed to suppress certain myocardial infarction risk factors, such as elevated serum homocysteine and inflammation, generally counterproductive? Loss of ciliary activity in organ cultures of rat trachea treated with lipo-oligosaccharide from Haemophilus influenzae.

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In both instances, granule cells migrated tangentially along the pial surface, migrated into the internal granular layer, developed dendritic arbors, and formed synaptic contacts with the processes of Golgi cells and with mossy fibers. They consider doses from inhalation, ingestion of contaminated food, air immersion, and ground deposition. Protein--DNA contacts in the structure of a homeodomain--DNA complex determined by nuclear magnetic resonance spectroscopy in solution. The effects of the cyclooxygenase inhibitor acetylsalicylic acid (ASA) and of the TXA2 receptor antagonist BM 13177 on blood pressure and on the efficiency of antihypertensive drugs were investigated in spontaneously hypertensive rats (SHR).