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Quantitative morphologic study of intimal thickening at the human carotid bifurcation: II. These changes are considered to be under direct immunological control rather than a non-specific consequence of the inflammatory reaction to the infective agent.

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This study determined the production of IL-1beta, IL-2, IL-4, IL-6, IL-10, IFNgamma and TNF-alpha in response to a synthetic material implanted in a rat soft tissue model for up to 90 days. Surprisingly, PAF receptor antagonists have not clearly proven their clinical benefits. The count of large granule-containing lymphocytes in patients with lymphoproliferative diseases Quantitation of cellular tubulin in microtubules and tubulin pools by a competitive ELISA.

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The versatility of the instrument is demonstrated by imaging cells and reading out a DNA-chip. Real-time monitoring of the gas phase reactions of a single ion population using the remeasurement experiment in Fourier transform ion cyclotron resonance mass spectrometry. Micturitional vesicourethral static pressure profile, a method of recording the static (lateral) component of voiding pressure in the successive urethral segments contiguous with the bladder, has allowed us to establish directly the site and degree of bladder outlet obstruction in 16 men. The alpha 3MG provides greater protection than either the beta or the equilibrated compound, as indicated by plasma glucose concentrations 24 hours after the experiment. Muscimol (3 mg/kg) significantly increased the DOPAC level in all parts of the mouse brain and the HVA level in the cortex, striatum, and midbrain.

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17beta-estradiol rapidly mobilizes intracellular calcium from ryanodine-receptor-gated stores via a PKC-PKA-Erk-dependent pathway in the human eccrine sweat gland cell line NCL-SG3. The preclinical activity profile combined with the hematological toxicity data in rodents and the water solubility of the compound compare favorably with MMC.

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Conduction of vasoconstrictor and vasodilator responses in the microcirculation involves electrical coupling through gap junction channels among cells of the vascular wall. Significant and equivalent post-training gains were found in visuo-spatial short-term memory in both groups. Thus, a global data set of water temperature is required to understand and synthesize global, long-term trends in surface water temperatures of inland bodies of water. In summary, our findings indicate that IH rapidly and persistently activates a central circuit that includes the NTS, forebrain lamina terminalis, and the PVN.

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Determination of the radiosensitivity of HeLa cells in relation to their stage in the generation cycle In contrast, the monoclonals raised against guinea pig Ia had much less dramatic effects on the response of uncloned T cells to these antigens. B-1 cells represent a subpopulation of B cells that has been extensively studied in mice and shown to spontaneously generate natural antibody that provides antimicrobial protection and helps dispose of cellular debris.

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The objective of this investigation was to examine the morphological (hair cell loss) and functional (BAER threshold elevations) changes resulting from toluene administration. Number of procedures per 100,000 population performed at Medicare-certified ASCs in 2012. Hospital records were obtained for patients given a diagnosis of stroke or transient ischemic attack (TIA) by an EMS dispatcher, EMT, or paramedic.

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In addition to identification of sites of drug action, brain imaging studies can be used to identify classes of drug action, interactions between drugs, and, perhaps more than any other technique, enhance the appreciation of the similarities and differences between the effects in animals and those in humans. Thus the TA-metal salt methods are pH dependent and allow differential intracellular and extracellular localization of complex carbohydrates in cartilage tissues at the electron microscope level.

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Myocardial scintigraphy with 201Tl was performed at rest in a selected group of 36 patients with unequivocal clinical and electrocardiographic evidence of old myocardial infarction. Smoking was related to lower cardiorespiratory fitness and respiratory function. All species but spotted wolffish showed strong EROD induction in tip pieces of gill filaments following 48 h of exposure to waterborne beta-naphthoflavone. Theory and practice of International Comparative Study in collaboration with Japan.

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The workflow of TagFinder comprises, (i) the import of fragment ion data, namely mass, time and arbitrary abundance (intensity), from a chromatography file interchange format or from peak lists provided by other chromatogram pre-processing software, (ii) the annotation of sample information and grouping of samples into classes, (iii) the RI calculation, (iv) the binning of observed fragment ions of equal mass from different chromatograms into RI windows, (v) the combination of these bins, so-called mass tags, into time groups of co-eluting fragment ions, (vi) the test of time groups for intensity correlated mass tags, (vii) the data matrix generation and (viii) the extraction of selective mass tags supported by compound identification. Thus, ALA and EPA inhibit antioxidant defenses of the cell and damage the DNA, which can ultimately lead to tumor cell lysis.

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A new approach for the surgical treatment of late post-total gastrectomy syndromes. Effect of a UHF electrical field of varying intensity on the development and course of experimental osteomyelitis of the mandible Second, several clonotypes that are normally only transiently expressed at 1 wk of age are preferentially expanded and preserved within the responsive B cell pool. Determine the level of knowledge of the general practitioners on the early phase of Lyme borreliosis in an endemic area and notably to define the attention paid to the use and interpretation of serologic investigations for the treatment of patients with erythema migrans.

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Serial lateral and posteroanterior cephalograms, obtained just before lip repair at 4 months or palatoplasty at 2 years, and at 4 and 8 years of age, were analyzed through comparisons with the means and growth increments of craniofacial dimensions. These clinical results support the usefulness of the nude mouse model for malignant mesothelioma. Experiments and comparisons on real-world multi-graph learning tasks demonstrate the algorithm performance. Although the fusion proteins (PA-PGA and PA-PGC) were not expressed at high levels and were almost totally recovered from the insoluble fraction, the renaturation and purification procedures were easy and simple.

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Operating department staff are usually required to wear dedicated theatre shoes whilst in the theatre area but there is little evidence to support the beneficial use of theatre shoes. Signal transducers and activators of transcription 3 signaling pathway: an essential mediator of inflammatory bowel disease and other forms of intestinal inflammation.

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These findings suggest that alterations in S2 receptors in the prefrontal cortex may reflect the disease process, per se, and that the increase in the number of D2 receptors in the caudate nucleus of schizophrenics is not due solely to neuroleptic medication. Structure-activity relationships of synthetic methyl ursolate glycosides. Additionally, our case report suggests that in some patients, a differential response is found regarding seizure control with R-VNS or L-VNS, raising the question whether L-VNS failures should pursue a trial of R-VNS. Heparin-induced impairment of phagocytic and catabolic functions of the reticuloendothelial system in rats.

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Technetium-99m-methylene-diphosphonate (Tc-99m-MDP) labeling was used to quantify mineralization of cultures of MC3T3 osteoblast-like cells in vitro. Typically periventricular lesions in the later chronic stages are similar to those in multiple sclerosis.

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It has been generally assumed that as genetic risk rises, so the higher procedure-related miscarriage rates of diagnostic tests done earlier in gestation become more acceptable. The capacity to quantify prognosis has clinical, policy, and research applications.

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Molecular cloning of cDNA coding for the 68 kDa allergen of Penicillium notatum using MoAbs. Serum CA19-9 levels were measured serially after chemotherapy in 13 of 14 evaluable patients. To establish diagnosis criteria and severity scoring system for multiple organ dysfunction syndrome (MODS) with integrated Chinese traditional and western medicine for MODS according to the principles of evidence-based medicine. It can therefore be concluded that the use of an IUCD does not increase the incidence of squamous intraepithelial lesions. injections of PGF-2 alpha (1 mg/kg) or PGE-2 (5 mg/kg) on Day 18.

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The magnitude of Klebsiella adherence was nearly 20 fold greater than all other species tested. These data provide additional evidence on the safety profile of insulin glargine in young children (Clinical trial identifier: NCT00993473). As predicted from reactance theory, it was found that the mere opportunity to shock the experimenter reduced hostility that was produced by his insulting behavior.

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While previous research has indicated that the birth outcome of the mother is an important determinant of the birth outcome of her offspring, these data indicate that the birth outcome of the father plays an equally critical role in determining fetal growth, strongly suggesting a genetic component in the familial aggregation of small for gestational age. Deoxyadenosine metabolism in the erythrocytes of children with severe, combined immunodeficiency. There was a good success in 46 patients, in all patients satisfactory results could be registered. Key objectives of biogerontology are to understand the biology of aging and to translate scientific insight into interventions that improve late-life health - or anti-aging treatments. Moderate, rapidly induced hypertension as a cause of intraventricular hemorrhage in the newborn beagle model.

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High rates of asymptomatic infection in male partners of infected females and subsequent re-infection have significant implications for control programmes. The four diets were preserved as hay and coarsely chopped prior to feeding in a 4 x 4 Latin square design. Dynabelt: a girdle for postoperative abdominal and thoracic protection Phase I trial and pharmacokinetic studies of alpha-difluoromethylornithine--an inhibitor of polyamine biosynthesis. Higher order groups were defined as supergroups designated A to D.

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Microapplicator and micropipette for inoculation of the embryonated chicken egg. The low plasma alkaline phosphatase (ALP) activity of the IS strain of rats was genetically analyzed by using the cross matings with the BN strain. Performed in good condition the procedure is very safe and simple to achieve. Neurons that synthesized the SCPs also contained SCP-like activity, as determined by snail heart bioassay.

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However, the loss of ability to escape behavior only is selective and sensitive to neuroleptics action. Paralytic shellfish toxin content is related to genomic sxtA4 copy number in Alexandrium minutum strains. Biosynthesis and secretion of catalytically active acetylcholinesterase in Xenopus oocytes microinjected with mRNA from rat brain and from Torpedo electric organ.

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Antioxidant supplements may be advocated as one medical therapy for chronic pancreatitis patients with low antioxidant capacity in their blood. Hydrogen sulfide releasing naproxen offers better anti-inflammatory and chondroprotective effect relative to naproxen in a rat model of zymosan induced arthritis.

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FISH analysis for chromosomes 13, 16, 18, 21, 22, X and Y in all blastomeres of IVF pre-embryos from 144 randomly selected donated human oocytes and impact on pre-embryo morphology. Relationship between genetic polymorphisms in MCP-1, CCR-2, and non-small-cell lung cancer in the Han nationality of Northern China. The results suggested that this population reflected many of the same characteristics seen in well-maintained patients. However, NaBu was not able to induce the p2 1/Waf1 production when the expression of TP53 was transiently knocked down by the p53 siRNA. Patients with type 2 diabetes diagnosed between 1995 and 2011 were retrieved from the Clinical Practice Research Datalink in the U.K., and followed from diagnosis until event of MI or end of study in 2013.

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We developed and implemented a technique to present a molecule of interest at the cell surface in an inducible manner on a time scale of minutes. Function of DNA polymerase I in RNA-primed synthesis of bacteriophage M-13 duplex DNA.

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This study sought to achieve an understanding of the true structural heterogeneity of hypertrophic cardiomyopathy. The Kessler-Levine model is a two-component reaction-diffusion system that describes spatiotemporal dynamics of the messenger molecules in a cell-to-cell signaling process during the aggregation of social amoeba cells. Inhaled or reduced-dose intravenous pentamidine may be an effective and less toxic therapy for mild P. Among women in their seventh decade, those with 15 or more teeth showed significantly greater mandibular cortical width than those with fewer teeth.

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The ability of v-Src-transformed cells to proliferate in low serum was also inhibited by okadaic acid. Moreover, expression of the mb-1 (Igalpha) gene and VH-to-DHJH recombination at the IgH locus are reduced in Pax5-deficient B lymphocytes approximately 10- and approximately 50-fold, respectively. Medical and surgical treatments are discussed pointing out the indications and the complications of hemispherectomy. Unresponsiveness was more easily induced in neonates than adults. The inefficient repair of CPD at the genome overall level occurs in the absence of massive apoptosis, but goes along with an undetectable level of transcription of the p48 gene, known to be mutated in xeroderma pigmentosum group E (XP-E) patients and recently proposed to be essential for repair of CPD in nonexpressed DNA.

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An EcoRV polymorphism at the ovine Menkes disease locus (ATP7A). Questionnaires were sent out to different Caribbean countries for distribution to the dialysis units.

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A one-way aqueductal valve resulting from the ventricular inflammation is hypothesized. Thus, the tumor cells in certain patients with CTCL may derive from a monoclonal proliferation of a T-cell subset capable of producing humoral bone-resorbing factor(s) similar to those demonstrated in cultures of mitogen- and antigen-activated normal lymphocytes. Premedication with the alpha(2)-adrenoceptor agonist clonidine is as good as with benzodiazepines in combination with TCI. Results from the current study suggest that CKD is common amongst SCD patients and prevalence and intensity increases with age.

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The aim of this study was to explore the association between psychosocial variables and somatic complaints in terms of the biopsychosocial model. The relationship between physical fitness and field independence was assessed by measuring embedded-figures test performance in the following four groups of children in Grades 4 through 6: (1) 93 boys high in physical fitness, (2) 92 girls high in physical fitness, (3) 67 boys low in physical fitness, and (4) 77 girls low in physical fitness. The results suggest that students at the participating institutions across selected European countries exhibit overall similar patterns of perceptions as have been found on American college campuses. We therefore studied the ability of nontypeable Haemophilus influenzae (NTHi) strains from children to form biofilms in vitro under conditions we presumed occurred in the middle ear during AOM, rAOM, and OME.

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The ATP-sensitive potassium channels can be pharmacologically modulated by a family of structurally diverse agents of varied potency and selectivity, collectively known as potassium channel openers and blockers. Immunogenicity of microdoses of a purified preparation of hepatitis B virus surface antigen As a result, the electric field close to the surface of the ionized self-assembled monolayer is weak and has little influence on the orientation and hydrogen bonding of the water molecules. The effect of energy deprivation and hyperosmolarity upon tubular structures and electrophysiological parameters of muscle fibres. The evolution and spread of antibiotic resistance depends on the antibiotic pressure exerted in the microbial environment.

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In an effort to understand the cellular and molecular basis, the in vitro and in vivo cataractogenetic effects of these smoke condensates have been studied using isolated rat lenses and pigmented rats. Emergency laparoscopic-assisted versus open right hemicolectomy for obstructing right-sided colonic carcinoma: a comparative study of short-term clinical outcomes. Diurnal variation of serum cortisol was established two days before operation. Granulomatous dermatoses can show positive lepromin-tests, but the histological picture is different from the lepromin reaction in tuberculoid lepra.

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Atlanto-axial rotatory fixation associated with the 18q- syndrome. Ion selectivity of pore-forming peptides and ion channels measured in Xenopus oocytes. Interleukin-10 Levels and Clinical Outcome : Comparison of Retroperitoneal versus Transperitoneal Approaches in Infra-Renal Abdominal Aorta Reconstruction. Cross-linked hemoglobin retained considerable ability to bind haptoglobin, although the amounts bound were reduced and the haptoglobin reaction could be used to fractionate the modified hemoglobin.