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ntl mutant embryos resemble mouse T/T mutant embryos in that they lack a differentiated notochord and the caudal region of their bodies. No significant decrease in cell attachment was noted in medium containing the mock oligopeptide sequence CDPGYIGSK. Early detection of infection and complications are important goals to reduce major complications after lung transplantation.

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Adriamycin resistance was partially overcome by the addition of verapamil or cyclosporin A, but cross-resistance to mitomycin C was not influenced at all. Antidiabetic AD4743 enhances adipocyte differentiation of 3T3 T mesenchymal stem cells.

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PAX6 does not regulate Nfia and Nfib expression during neocortical development. Cervical spine dysraphism with teratoma exhibiting pulmonary differentiation: case report and review of the literature. The evidence for these proposals is reviewed, highlighting recent findings indicating that Swe1p degradation is controlled by the cell shape change that accompanies bud emergence. Comparison of the PCA titer and aerosol microshock time in guinea pigs made sensitive to ragweed.

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Persistent epithelial defects are a common complication after severe alkaline corneal burns. The columns permit high flow-rates and the resolution is about the same at low and high flow-rates. An improved method of discerning emotional colouring of speech on the frequency of main tone and average number of intersections at zero level within the range of first formant frequencies is described.

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Even after a successful transplantation, rejection and side effects of immunosuppression remain major concerns for graft survival and patient morbidity. Return of fear in a human differential conditioning paradigm caused by a return to the original acquistion context. The correlation between cysto-urethroscopic, cystometric and urodynamic findings. It has been generally postulated that dissociation of the BiP-ATF6 complex is a result of the competitive binding of misfolded proteins generated during ER stress. Sotalol-induced torsades de pointes successfully treated with hemodialysis after failure of conventional therapy.

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Development of a 5-step multi-chamber reactor as a simulation of the human intestinal microbial ecosystem. Several of the proteins were present in more than one spot suggesting post-translational modification. Observed mutations included single-nucleotide variations and indels leading to frame shifts, nonsense, missense or splice-site alterations. Bacillus cereus panophthalmitis associated with injection drug use.

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Here we have located three specific DDR2 binding sites by screening the entire triple-helical domain of collagen II, using the Collagen II Toolkit, a set of overlapping triple-helical peptides. Although it is not currently a common practice, emergency physicians can be trained to perform this diagnostic procedure and interpret the resulting scanning images. As the cause of death, we assumed a rupture of the pseudoaneurysm. Semi-automatic catalytic titration method for the analysis of cystine-cysteine mixtures and its application to urine samples.

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It may assist the development of strategies to prevent physical abuse of children with disabilities. Fifty nonunions of the upper two-thirds of the humerus were treated by two different methods: 24 of them by unreamed locked nailing and bone graft (group A), and the other 26 by plate fixation and bone grafting (group B). This study was aimed to assess the pattern of burden borne by the family caregivers of patients with opioid-dependence-injecting drug users (IDU) and noninjecting drug users (NIDU). Planar scintigraphy showed good correlation with SPECT in determining the presence or absence of abnormality in all patients except one with a very small brain stem infarction that was not detected by planar imaging.

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Findings included significantly lower ages for those patients in whom infections were right-sided. For almost 40 years following its discovery, substance P resisted isolation and purification. Recursion in development: support for a biological model of language. Preimplantation embryos were collected on day 3 of pregnancy, four to eight-cell embryos were cultured in vitro 48 h (day 5) and their cell number was estimated. Here we report that expression of the glc1.8 gene from Microplitis demolitor bracovirus (MdBV) causes a loss of adhesion by two hemocyte-like cell lines, namely, High Five cells from the lepidopteran Trichoplusia ni and S2 cells from the dipteran Drosophila melanogaster.

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Reversal of secondary hyperparathyroidism by cimetidine in chronically uremic dogs. The latter, in turn, could be attributed either to later-than-normal arrival of excitation at the atrioventricular node, at a time when this structure was more recovered, or to a change in the site or mode of entry into the atrioventricular node. These 21 cases were comprised of 12 cases of stomach cancer, 1 case of lymphosarcoma, 4 cases of rectal cancer, 2 cases of sigmoid cancer and 2 cases of breast cancer.

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A case of chronic sensory neuropathy with immunological abnormalities Although the SWAT model has been used extensively for modeling P loss in runoff and includes tile drain flow, P losses are not simulated in tile drain flow. Neither the presence of metabolic syndrome as defined by the IDF guideline nor an increased waist circumference increased the risk of microvascular or macrovascular complications in Japanese patients with type 2 diabetes. Cellular metabolism is highly dynamic and continuously adjusts to the physiological program of the cell.

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The plasma cell response to tin may be due to local polyclonal activation. The equations available for the prediction of basal energy expenditure (BEE) may not be applicable in morbid obese individuals since the contribution of the fat free mass (FFM) over the BEE is not constant.

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Lattice Monte Carlo (MC) simulations provide an efficient method for exploring the structure and phase behavior of block polymer melts. It may occur also without treatment, after a longer implantation time. Controlled trials were sought, but due to their relative rarity, most articles cited are well designed retrospective studies and reviews. Recent molecular and imaging insights into radiobiology will provide a unique opportunity for rational patient treatment, enabling the parallel design of next-generation trials that formally examine the therapeutic outcome of adding targeted drugs to radiation, together with the critically important assessment of radiation volume and dose-limiting treatment toxicities.

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Taken together, our results suggest that Restin inhibits EMT and tumor metastasis by controlling the expression of the tumor metastasis suppressor mir-200a/b via association with p73. In this study, we demonstrate that, like the degradation of ubiquitin-conjugated proteins, ubiquitin-independent degradation of ODC also requires prior assembly of the mammalian 26S proteasome from all the three subunits, the 20S proteasome and the two subcomplexes. Morphometric measurements showed a gradual enlargement in glomerular size without any increase in the number of podocytes in the glomerulus. Preliminary results of rectal urine analysis support this theory in that high concentrations of N-nitrosamine have been found mutagens demonstrated. We have investigated the basis of incompatibility exerted by the F plasmid centromere, sopC, to probe the mechanism of partition.

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There is fear, however, that the inadvertent nonaccident-connected deployment of one of these air bags might substantially interfere with the handling of a vehicle in which such deployment occurred. Simple modifications can be made to preexisting 1.5-T protocols to obtain image quality at 3 T that is comparable to that at 1.5 T. PEMs proliferate through three developmental stages, PEM I, II, and III, by changes in the number of ECs and SCs. Acoustic neuroma: correlation among tumor size, symptoms, and patient age.

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Our study was designed to investigate the safety and efficacy of combined autologous bone marrow mononuclear cell (MNC) and gene therapy in comparison to conventional drug therapy in patients with critical limb ischemia (CLI). This followed a review of current evidence by the clinical team and a change in local testing policy.

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Quantitative determination of argemone oil in edible oils by thin layer chromatography. The linear stapler is used to transsect the sigmoid colon and to dissect the entire mesentery. Remarkable cellular infiltrations into the tumor nests, such as neutrophils, lymphocytes, macrophages and plasma cells were observed and these cellular infiltrations after the preoperative irradiation were more remarkable than the cases without radiotherapy or with conventional fractionated radiotherapy. The results indicate that Mg deficiency can reduce the nutritive utilization of protein, an effect that may contribute to the appearance of the malnutrition syndrome in rats given an Mg-deficient diet.

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Trace lipopolysaccharide (LPS) contamination was not responsible for the mitogenic effect, as shown by the ability of C3H/HeJ spleen cells to proliferate in response to PRP and by the failure of polymyxin B to inhibit PRP-induced DNA synthesis. The function of the c-Myc oncoprotein and its role in cell growth control is unclear.

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The classical therapy with streptokinase has the disadvantages of antigenicity and of a considerable influence on the clotting system. Here we describe a new activity for ACE: a glycosylphosphatidylinositol (GPI)-anchored protein releasing activity (GPIase activity).

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Opioid analgesia alone may not fully relieve all aspects of acute postoperative pain. Administration of cephalothin to normal volunteers in maximal doses of 300 mg/kg per day resulted in a combined defect of platelet function and blood coagulation.

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Whole homogenates and membrane-bound and cytosoluble fractions prepared from rat ventral tegmental area (VTA) and nucleus accumbens were examined for their content of peptidasic activities and for their ability to metabolize neurotensin and its natural related hexapeptide neuromedin N. Simultaneous MR imaging did not appear to have an effect on the physiological signals acquired by means of the contact-free monitoring system. After 11 weeks of CL severe hyperopia was observed (18.2 vs 2.8 D). The method facilitates automated thrombus segmentation for accurate length and volume measurements, is relatively fast and requires minimal user input, while being insensitive to high hematocrit levels and vascular calcifications. There was no evidence that olfactory processes had undergone any adaptation during pregnancy.

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The first granule-containing cells, phaeochromoblasts, were seen at day 15 of gestation migrating into the anlage of the cortex. intermedius strains were metabolically almost identical, expressed at least three of the recognized antigens, and fell into three distinct antibody reactivity groups, suggesting a tentative separation of this species into three new serogroups. However, culture supernatants from LPS-stimulated epithelioid cells showed significantly higher IL-1 activity than those from unstimulated cells. In truncus arteriosus communis, as in other anomalies of conotruncal development, the coronary arterial anatomy not only differs from that found in the normal heart but also is subject to unpredictable variations. Prostaglandin anthrylmethyl ester: a membrane-permeant fluorescent analogue of prostaglandin with enhanced cell growth inhibitory activity.

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Efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. Aortic repair by graft replacement is currently the most generally accepted and widely used technique in the treatment of infrarenal abdominal aortic aneurysm. Hyperactivated sperm motility driven by CatSper2 is required for fertilization. A number of 996, matched on age and sex, were selected as controls. Surgical closure of membranous ventricular septal defect (VSD) is performed by open heart surgery with a small but significant morbidity and mortality.

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Dimethyl sulfoxide inhibits proliferation but not hypertrophy and functional dedifferentiation of bovine parathyroid cells in culture. Evaluations were tender point examination and questionnaires, including visual analog scales (pain intensity at worst site, muscular stiffness, evening fatigue, and global health), Fibromyalgia Impact Questionnaire (FIQ), Coping Strategies Questionnaire, Quality of Life Scales, Arthritis Self-Efficacy Scale (ASES), and disability before, immediately after, and at 6 and 18 months follow-up. Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA. Nucleotide sequence of the phosphofructokinase gene from Bacillus stearothermophilus and comparison with the homologous Escherichia coli gene.

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Phenotype-genotype correlations in skeletal muscle of patients with mtDNA deletions. A strong negative correlation was found between specific trust and empathy.

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Lesions in other brain regions did not cause alterations in the septal CRFI fibers. A randomized controlled clinical trial was performed with 446 nulliparous women with deliveries after 28 weeks of pregnancy. Results indicated that American Indian youth were not as adversely affected by these neighborhood factors.

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Animals house in chronic dark for 7 days maintained the diurnal variation of alpha-MSH concentrations. The purpose of this study was to identify findings that aid in differentiating autoimmune pancreatitis from pancreatic carcinoma using dual-phase CT. Temporomandibular joint disorders (TMD) are not uncommon in patients with rheumatoid arthritis (RA). The increase has been observed in all diagnostic categories although the greatest increase, by percentage, has been for psychotic disorders. Methodology and results of total acoustic neurinoma removal using microsurgical technics

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ARIF is recommended for displaced type III fractures and should be considered for all cases of displaced type II fractures. The interaction effect of bereavement and sex on the risk of suicide in the elderly: an historical cohort study. We also outline priorities for the development of practice, education, and research.

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Thus, transesophageal echo-cardiography may have a significant impact on the management of these patients. The presence of the striated MR nephrogram was correlated with imaging parameters (field strength, time since contrast), and findings (gadolinium in the bladder, inferior vena cava and aorta diameters) and with clinical factors (history of renal disease, laboratory values). Correlative analysis between the results of several examinations and the prognosis were performed respectively.

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Aggressive behavior can be reinforcing but the involvement of NAc DA in the reinforcing effects of aggression has yet to be demonstrated. Comparative analysis of natural and synthetic antimutagens as regulators of gene expression in human cells under exposure to ionizing radiation Further, one mycoplasmal species activates lymphocytes obtained from different species. This study shows that in patients with type 2 diabetes who were not selected for liver abnormalities, liver fat content was related to GCKR rs1260326 polymorphism independent of BMI, triglyceride levels, and age. Hence, in the intact caudate-putamen dopamine appears to normally suppress expression of these two neuropeptide genes.

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Effects of level and type of energy source (volatile fatty acids or glucose) on milk yield, composition and coagulating properties in dairy cows. A total of 34 consecutive patients (mean age 55.8 y) with cervicogenic headache (in addition to cervical stenosis symptomatology) resistant to nonoperative treatment were treated by anterior cervical decompression and fusion from 1 up to 3 levels and were followed for at least 1 year. The effect of asparaginase on acrylamide formation in French fries. We have developed a laser scanning device for this purpose, which has the potential to obtain the surface geometry in real-time. Although both yielding antihelical duplexes, the two modes are not equivalent regarding cladistic relations between homologs.

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By post-myelography computed tomographic scan criteria, our frequency of asymptomatic thoracic herniated discs (ATHDs) was calculated. A total of 37 patients with acute monocular blindness because of unilateral thromboembolic CRAO were treated with IAT using urokinase within six hours of the onset of symptoms. As TAFs are required for activated but not basal transcription, we have proposed that TAFs act as coactivators to mediate signals between activators and the basal transcription machinery.

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The clinical presentation and neuroradiological findings of these tumors may be deceptive and resemble to the other most prevalent brain tumors. An 82-year-old woman was transferred to our intensive care unit because of a sudden decrease of consciousness level, right hemiparesis, and acute respiratory failure in the early postoperative period of knee prosthesis surgery. Here we show polo-like kinase 1 (PLK1) and HSF1 interact in vivo using the tandem affinity purification system.

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NS-3 (CG3703), an analog of thyrotropin-releasing hormone, ameliorates cognitive impairment in rats. However, preincubation with 1 mM Verapamil did not alter the inhibitory effect of capsaicin. The distances pulled to reach the ultimate loads which seem to represent the extensibility and elasticity of the periodontium correlated closely with the ultimate loads. Influence of water temperature and beta-blockade on blood pressure, degree of cardiac hypertrophy and cardiac function in swimming training of spontaneously hypertensive rats. Databases searched included MEDLINE, EMBASE, Scopus and Cochrane Library.

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These results point to a potent regulation of MMP-1 by mechanical stress relaxation, a process depending on de novo protein synthesis and occurring independently of the activation of an IL-1 autocrine feedback loop. The outer layer of epimysium was composed of several wavy sheets of collagen fibers which ran transversely to the axis of the muscle fiber. High grade sarcomas are associated with microsatellite instability (chromosom 12) and loss of heterozygosity (chromosom 2). Pharmacological therapies in ischemic stroke have made limited progress in recent years. Pretreatment of cells with the antioxidant N-acetylcysteine inhibited plumbagin-mediated ROS generation and apoptosis.

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Phosphate removal using hollow fibers containing aluminium oxide. Effect of psychoytopic drugs on high affinity choline uptake by excised tissue of rat nucleus caudatus. Serum prolactin was elevated in all cases and fell to normal nonpregnant levels immediately after CB-154 was administered. Pseudomonas aeruginosa as viewed from the standpoint of opportunistic infection Previously, we showed that human glioma cells selectively transfected with the gene of interferon (IFN)-beta and/or IFN-gamma by our novel liposomes tagged with monoclonal antibody against a glioma-associated antigen achieved a remarkable growth inhibition effect.

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Interferon (IFN) (at least 16 units/ml) was demonstrated in suction blister fluid obtained from lesional skin in nine of thirteen patients with psoriasis vulgaris and in two patients with allergic contact dermatitis, but not in blister fluid from unaffected skin. However, the trials also confirmed that the addition of the lignite (brown coal) into the anaerobically digested sludge led to a more productive drying process, improved product quality and a greater fraction of the product being in the desired product size range. 13 patients with colorectal cancer of different stages and grades. To evaluate the influence of high-pitch mode (HPM) in dual-source computed tomography (DSCT) on the accuracy of three-dimensional (3D) volumetry for solid pulmonary nodules. Growth inhibition of human keratinocytes by 1,25-dihydroxyvitamin D3 is linked to dephosphorylation of retinoblastoma gene product.

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Examination of sperm morphology and assay of in vitro sperm viability by use of a thermoresistance test, incubation with ouabain and assay of ASAT-release was performed in 10 ejaculates from each of 10 boars during a 7-month period. Serological data, however, strongly suggest that subclinical infection without overt disease occurs following contact with human and other animal infectious agents. Our objective was to isolate glycosaminoglycans from various regions of the female bovine reproductive tract to ascertain their concentrations and composition. The occurrence of gamma-glutamylphenylalanine in the urine of patients with phenylketonuria could be demonstrated using chromatographic techniques and mass spectrometry. The effect of age on the plasticity of the putative peptide neurotransmitter substance P (SP) was examined in the rat superior cervical sympathetic ganglion.

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Enhancement of interleukin-4-mediated tumor regression in athymic mice by in situ retroviral gene transfer. Primary amyloidosis of the lower urinary tract is a rare condition with an excellent prognosis in most cases.