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Acifar (Acyclovir)

Acifar is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Acifar is converted to an active form by the virus itself, and the virus then uses the active form of Acifar rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Acifar into new viral DNA stops the production of the DNA. Virally infected cells absorb more Acifar than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Acifar in March 1982.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Plasma phenylalanine in patients with phenylketonuria self-managing their diet. Recommendations from subject experts in two areas--AIDS, and toxicology and environmental health--led to the development of two subject-specific Gophers.

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Characterization of antibody and T cell-mediated responses to the N-terminal peptide of hen egg-white lysozyme. A standard technique of microbial genetics, which involves the transfer of cells from single colonies by means of sterile toothpicks, has been adapted to somatic cell genetics. NP-D-GL and NP-Ficoll failed to induce Ts3 cells, whereas NP-L-GL induced this suppressor subset. Self-quantification in personal health maintenance appears promising and exciting. When normal B cells and CLL cells were mixed, incubated, and lysed together, both 225- and 185-MICG were present, thus excluding proteolysis as a cause of the absence of 185-MICG in CLL.

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These were small and medium residues as Gly, Ala, Ser, and Leu, which also had the possibility to form interhelical Calpha-H...O hydrogen bonds. Explaining the efficacy of indigenous therapies: the need for interdisciplinary research. The kidney miRNA pattern is broadly altered in LN, which contributes to uncontrolled cell proliferation. Isolation and characterization of plasmid-deletion derivatives from an Hfr made with Rts1 plasmid carrying a chromosomal mutation, plt. By increasing the ionic strength of the lower gel buffer, separation of protein I and the 37,000-dalton iron-regulated protein occurred.

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Primary outcome addressed the number of intraepithelial neoplasias detected in each group. In this paper, the interpretation of averaged pharmacological effect data for the cardiac glycoside digoxin is reconsidered through a comparison with theoretically simulated data. These data suggest that GRF may be a new biologic marker for pancreatic endocrine tumors. The present study focused on evaluating whether or not previously enucleated mouse oocytes are usable for the analysis of human sperm chromosomes. The study suggests that similar training programs should use a feference manual as a focus for didactic training and that the acquisition of skills is best accomplished in small groups of 2 to 3 trainees per instructor.

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More subgenotype studies are required to conclude on subgenotype and its clinical/viral characteristics. To determine whether human papillomavirus (HPV) was responsible for symptoms in women with vulvar pruritus, pain and superficial dyspareunia who had been referred with a diagnosis of HPV vulvar disease made on clinical and/or colposcopic and/or histological grounds. But the most striking result was the high level of uncertainty in the answers with respect to medical aspects of advance directives. The activity of the G-cell and the molecular forms of gastrin are not changed by TV.

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Here, we review our understanding of the origin of the UB and the MM in mouse, and discuss how this impacts on kidney regeneration strategies and furthers our understanding of human development. KA is quite likely to be useful as a systemic anticancer agent against colorectal malignancy.

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The aim of this study was to investigate the possible effects of NSO in I/R-induced renal injury in rats. Skin aging principles play important roles in skin disease diagnosis, the evaluation of skin cosmetic effect, forensic identification and age identification in sports competition, etc. The detection of aberrant DNA synthesis in a member of a high-risk cancer family. The importance of closing defects created by surgery or disease in the posterosuperior bony canal is recognized, and numerous materials and techniques have been advocated. Morphological characteristics of serous ovarian adenocarcinomas after chemotherapy

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Osteochondritis dissecans of the tarsocrural joint was diagnosed in three canine siblings. A T cell model for age-related loss of homeostasis: identification of the cell type responsible for age-related delay in recovery of the PHA-induced mitogenic response from radiation injury.

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The thrombin clotting time was shortened after freeze-drying or heating at 47 degrees C, in spite of what might have been expected. This works represent a valuable step in enriching intuition and deepening understanding of the assumptions behind moment closure approximations and for putting them on a more rigorous mathematical footing. 24 influenza virus A (H3N2) strains were isolated from 467 pharyngeal swabs.

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Effect of glycemic control on intact parathyroid hormone level in end stage renal disease patients on maintenance hemodialysis. Conflicting evidence exists concerning whether insulin-induced vasodilation plays a mechanistic role in the regulation of limb glucose uptake. Intraperitoneal (ip) injection of a low dose of apomorphine (0.1 mg/kg), which preferentially activates presynaptic dopamine autoreceptors, produced a lower frequency of yawning responses in 12- and 24-month-old rats than in 2-month-old rats.

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Definitions of osteosarcoma, chondrosarcoma, and fibrosarcoma of bone. The genital tract is usually infected by hematogenous spread from a distant focus, with the fallopian tubes most commonly involved. Acute effects of selected hepatocarcinogens on polyribosomes and protein synthesis in the livers of rats fed purified diets containing hepatocarcinogens. Pure pancreatic phospholipase A2 was activated only if the pancreatic juice was mixed with bile and its activation became more dominant when it entered into the duodenum.

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This apparent extra release of CK-MB runs parallel with massive release of CK-activity from skeletal muscle damaged by surgery. Specific thromboxane synthetase inhibition and haemostasis in insulin-dependent diabetics. Consistently negative results are obtained with separate assays that measure antibody binding to uncharged receptors or to charged receptor complexes that have been preloaded with a specific steroid ligand.

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School time, or time spent interacting with the instructor, another student, and/or the student on his/her own in the practice setting (time exclusive of staff input) constituted 84 per cent of all time. Casein, hydrolyzed casein, and amino acids that simulate casein produce the same extent of mucosal adaptation to massive bowel resection in adult rats. Cell membrane fluidity in K562 cells and its relation to receptor expression. In contrast to the limited species effect of estrogen, known carcinogens such as 2-naphthylamine, nitrosamines or aflatoxin B1 produce tumor incidence in a variety of species. Pharmacokinetic studies on kanamycin administered intramuscularly in a dose of 30 mg/kg 1 hour before a surgical operation to dogs with 48-hour occlusive ileus showed a high level of the antibiotic penetration into the blood, lymph and blood of the small intestinal vascular system.

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Phytoecdysteroids are structural analogs of the insect molting hormone ecdysone. While the potential role for intravesical therapy is becoming clear, additional trails to test new agents, compare current agents, and refine dose, concentration, volume, and contact time are indicated. Gram-positive coccal species predominate throughout the reproductive cycle. He studied under some of the great teachers in Europe during the early 19th century and returned to the United States as a professor of surgery at Thomas Jefferson University in Philadelphia. When these novel agents were evaluated with a number of membrane proteins, it was found that XMA-4 and XMA-5 have particularly favourable efficacy with respect to membrane protein stabilisation, indicating that these agents hold significant potential for membrane protein structural study.

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The handbook draws from current global health education literature, existing handbooks, and expert experiences, and includes information about logistical and cultural preparations. The elevated levels of alpha 2 macroglobulin in the three groups are probably due to differences in the mean age of these groups compared with the reference population.

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The patient was diagnosed with cardiac syncope 3 months after total abdominal hysterectomy and was successfully treated with a two-stage approach consisting of sternotomy followed by laparotomy. This model-based study using ABCpred, BCPREDS, Bcepred, and Ellipro web servers showed that the peptide presented in this article has the necessary properties to act as a vaccine. The design of these receptors was inspired by the binding motifs observed in the crystal structures of protein-carbohydrate complexes. It shortened the period of clinical manifestation of the disease, hastened sanation of the liquor, influenced beneficially interferon production and modulated activity of the natural killers.

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The results of the study indicated that the number of blood vessels in gingival connective tissue is significantly higher in CP and CPDM patients. Novel mechanisms in the treatment of heart failure: inhibition of oxygen radicals and apoptosis by carvedilol. Supermolecular building blocks (SBBs) for the design and synthesis of highly porous metal-organic frameworks.

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Granulosa cells and Day 2 luteal cells of the ewe were cultured for three days and then treated for 30 min with varying doses of PGF2 alpha, LH, or estradiol. The distinction between fetus in fetus and teratoma has for long been the subject of controversy.

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Phototoxic Risk Assessments on Benzophenone Derivatives: Photobiochemical Assessments and Dermal Cassette-Dosing Pharmacokinetic Study. This effect is larger than the effect of specific feature reduction procedures on the MRSI data.

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The surgical-orthodontic correction of vertical dentofacial deformities. The patient underwent adrenalectomy and pyelolithotomy with histopathological and immunohistochemical diagnosis of adenomatoid tumor of adrenal gland, being the largest one described in the literature to the moment. In one case we have observed the development of trocar site abdominal wall metastasis twice. When the amplified products were hybridized with a complementary probe (MP5-4 oligonucleotide probe), thirty PCR-positive samples all gave positive hybridization signals. An important difference between healthy and pathological subjects is not the quality but the quantity of the changes induced by TENS, in the sense that the levels of inhibition and facilitation of the reflexes are more evident in patients with pain.

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The clinical presentation, isolation of the ameba from the cerebrospinal fluid and nasal passages, poor response to amphotericin B, and ultimate fatal outcome prove this to be a case of PAME. Long-term representation of programs requiring short-term memory can result from activity-dependent modifications of the synaptic transmission controlling the bistable behavior. Two auditory responsive regions in the telencephalon of the bullfrog were localized by combining systematic evoked potential depth recordings with subsequent histological studies. The remaining two animals from each group were prepared for histological evaluation. Excessive activation of the kinin system was noted in the blood flow and elevation of all types of proteolytic activity in the respiratory system.

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Perioperative use of TandemHeart percutaneous ventricular assist device in surgical repair of postinfarction ventricular septal defect. Among the latter is the fact that the diagnostic criteria for chronic migraine do not distinguish between cases differing widely in severity and that the issue of whether medication overuse headache can be considered an autonomous entity is still unsolved.

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Different segments of intestine affect the evacuation in different ways. Increases in neutrophil counts by purified human urinary colony-stimulating factor in chronic neutropenia of childhood. Only one hepatocellular carcinoma was observed in each treatment group. In addition, at lower dose levels (2.5 nM to 10 nM) PDot treatment resulted in higher total thiol level than those found with QDots. Graduates of Orthopaedic Residency Training Are Increasingly Subspecialized: A Review of the American Board of Orthopaedic Surgery Part II Database.

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Reversible inhibition of Sindbis virus penetration in hypertonic medium. Recordings were carried out with a mobile device consisting of two Medilog 4-24 recorders and one DMI-recorder assessing five biosignals: EEG, EOG, EMG, ECG and body movements.

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While chronotherapeutical approaches have been particularly successful in the treatment of hypertension, allergies and some forms of cancer, a time-dependent pharmacological approach can be also effective when dealing with sleep disruptions like insomnia. A novel method to produce armored double-stranded DNA by encapsulation of MS2 viral capsids. Recombinant somatropin in treatment of growth hormone deficient children in Sweden and Finland. Reversible inhibition of mammary gland growth by transforming growth factor-beta.

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It has been more than 50 years since the role of the geriatrician in the management of patients with a hip fracture was first described. Recurrent admissions contribute substantially to total emergency admissions. Nuclear accumulation of specifically bound 3H-R1881 was apparent after 5 min and preceded RNA polymerase II activation. Monoclonal antibody against an osteogenic-sarcoma cell line (791T) was prepared by production and cloning of a somatic-cell hybrid between the mouse myeloma P3-NS1 and spleen cells from 791T-immunized mice. Neither naloxone (3000 micrograms/kg) nor combined phentolamine (1500 micrograms/kg) with propranolol (300 micrograms/kg) altered postprandial antral or small intestinal motility.

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Evidence for the existence of factor(s) other than blood pressure responsible for modulation of myocardial hypertrophy accompanying hypertension is well documented. Phytohemagglutinin activation of lymphocytes: quantitative comparison of different preparations.

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Psychosocial factors were assessed by means of standardized questionnaires. 5-Hydroxtryptamine elicited more scratching than did substance P, which in turn caused a greater number of biting or licking responses. Overexpression of mdr1 gene-encoded permeability glycoprotein (P-gp) is known to play a pivotal role in the development of this phenotype.

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Neuropeptide G-protein-coupled receptors, their cognate ligands and behavior in Caenorhabditis elegans. Changes in the chemical composition of oospores of Pythium aphanidermatum during bimodal germination. Changes in thyroid function in pregnancy and with oral contraceptive use.

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It must be noted however that the interocclusal tactile threshold is not solely determined by periodontal mechanoreceptors but also by pulpal, muscular or articular receptors. Previously a cloned emetine-resistant mutant of the protozoal parasite Entamoeba histolytica was shown to overexpress a gene for an ameba homolog of the mammalian P-glycoprotein, a plasma membrane pump that removes hydrophobic drugs from multidrug-resistant tumor cells. The purpose of this article to is provide a brief overview of the LMA with special emphasis on its use in otolaryngology--head and neck surgery. There was evidence of horizontal transmission with sentinel pigs, in-contact with receiver pigs, becoming viraemic. The experimental results obtained in a model situation are in agreement with previous calculations (F.

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Andrological and hormonal findings in subjects with ductus deferens agenesia. The present study investigates whether there is an association between trait impulsivity in the normal population and inhibitory motor control as assessed by the stop task. Thus, our work provides one more example of the pitfalls of deducing regulatory roles from bioinformatic analyses only, even when analyzing gene clusters directing the synthesis of structurally related compounds.

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Angiotensin converting enzyme inhibitors during acute phase of myocardial infarct This device permits ready access to the patient so that monitoring and treatment can be carried on while cooling is in progress and is particularly adopted to use in the operating room.

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Physicochemical characterization of novel Schiff bases derived from developed bacterial cellulose 2,3-dialdehyde. Our study defines the threshold for cell loss in the embryonic mammalian heart and reveals a robust cardiomyocyte compensatory response that sustains normal fetal development. The rate of intraepithelial neoplastic progression is continuously driven by the dosage level of exposure to mutagens and mitogens. A wide spectrum of procedures are available to physicians to assist in the establishment of the diagnosis and extent of disease in soft tissue and bone sarcomas in childhood.

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We report a case of unilateral primary Burkitt lymphoma of the breast. The localization of zinc was investigated in specimens of hyperplastic prostate by means of light microscopy, electron microscopy, and x-ray microanalysis.

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Existence of T lymphocytes manifesting self-reactivity indistinguishable from alloreactivity: implications for self-recognition and MHC polymorphism. Thus, further assessment of this simple prognostic variable is warranted and selection of patients with positive cytology for possible adjuvant therapies may be beneficial.

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The importance of microtubules in mitosis makes them a superb target for a group of highly successful, chemically diverse anticancer drugs. Regulation of carnitine palmitoyltransferase by insulin results in decreased activity and decreased apparent Ki values for malonyl-CoA. Urinary microbiota in patients with prostate cancer and benign prostatic hyperplasia. The prognostic significance of microalbuminuria and its correlation with left ventricular hypertrophy has not been extensively studied in African adult hypertensive populations. A new cell line, GS, of human renal cell carcinoma was established and characterized.

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Visits to family doctors for mothercraft issues were less frequent. Scanning probe-based fabrication of 3D nanostructures via affinity templates, functional RNA, and meniscus-mediated surface remodeling. Seventeen GH-deficient adults were randomized to receive either daily LGH or placebo injections. A new genus and species of the marine parasitic nematode Abos bathycola gen.

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In hepatitis c treatment pegylated interferon and ribavirin long-term addition to the well-explored scaffolds for monovalent and bivalent Smac-mimetics, some companies have taken more drastic approaches to explore new chemical space - for example, fragment-based approaches and macrocyclic inhibitors. On the other hand, MT-II appeared to be expressed mainly in glial cells localized in the cerebral cortex and hippocampal formation.

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A technique for rapid evaluation of the afferent visual system in patients with multiple injuries is presented. Mean arterial blood pressure in diabetics was significantly higher than control and Mg-treated rats. Single-dose and steady-state pharmacokinetics of fosinopril and citox express coupons fosinoprilat in patients with hepatic impairment. This effect was not limited to melanoma cell types since LIF production was also enhanced by an MDA breast undifferentiated adenocarcinoma line.

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From these results, it is obvious that the main 67Ga-binding substances in these four organs are sulfated acid mucopolysaccharides, and that acimax omeprazole medication these acid mucopolysaccharides play the most important role in the concentration of 67Ga in these organs. Muscle-relaxant effect of amrinone on guinea-pig tracheal smooth muscle and its interaction with aminophylline The duration of the clinical effect of desmopressin administration varied in different patients between 4 and 23 h. The potential of C-phycocyanin (C-PC) to prevent cisplatin (CP)-induced kidney mitochondrial dysfunction was determined in CD-1 male mice.

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An in vivo situation analogous to that of corpus luteum grown in LDL-depleted media exists naturally in patients with abetalipoproteinemia. Persistence of organochlorine insecticides in the field in the Gezira soil under cotton. We attempted to validate a Leishmania mexicana ELISA exo-Ag for ATL diagnosis in Midwestern Brazil. This article reports on the state of the science regarding cholesterol, nutrition, and exercise education with teens and describes a health promotion program about this topic with 23 high school biology students. Effect of Dietary Resistant Starch on Prevention and Treatment of prostamide meaning of name Obesity-related Diseases and Its Possible Mechanisms.

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Purification and properties of 5,10-methenyltetrahydrofolate synthetase from Lactobacillus casei. A significant difference was noted between the number of dynorphin, enkephalin, somatostatin, cholecystokinin, avian pancreatic polypeptide, FMRF-NH2, neurotensin and vasoactive intestinal polypeptide immunoreactive citrol medication errors cells in the sacral parasympathetic nucleus and dorsal gray commissure.(ABSTRACT TRUNCATED AT 400 WORDS)

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The major function of plasmatic t-PA is the lysis of intravascular fibrin deposits. bactox 125 mg to g Moderate tension of the regulatory mechanisms in the lutein phase of the cycle was protective and adaptive and probably related to body preparation to a would-be pregnancy.

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Improved methods of identification of the contents of juxtaglomerular granules cyclophosphamide 50 mg j code for venofer may provide better methods of prediction of those patients likely to benefit from nephrectomy for hypertension associated with renal ischaemia. Sometimes it is difficult to predict who will benefit from liver transplantation. Antibodies to neutrophil cytoplasmic antigens induce monocyte chemoattractant protein-1 secretion from human monocytes. Though many conservative and intradiscal therapies for lumbar disc herniation have been developed, open disc surgery is still necessary.

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Modulation of P-glycoprotein function by amlodipine derivatives in brain microvessel endothelial cells of rats. Effect of electrostatic, hydrodynamic, and Brownian forces on particle trajectories and sieving in normal flow filtration. The clinical effect of substitution depends on the specific activity of the preparation, on the volume of expansion syscan 150 side effects in the recipient and on other pharmacokinetic factors.