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The human leukocyte-adhesion ligand, intercellular-adhesion molecule 2. The article provides an overview of the criteria-based content analysis used for judging the credibility of self-reports.

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Improving oral bioavailability of metformin hydrochloride using water-in-oil microemulsions and analysis of phase behavior after dilution. The most notable alterations in dogs experiencing a moderate or severe adverse reaction were a decrease in platelet numbers and fibrinogen level, a rise in serum transaminases, and the appearance of fibrin monomers. Health effects of air pollution due to coal combustion in the Chestnut Ridge region of Pennsylvania: cross-section survey of children. Malformations occurring in the lower limb seem to have a considerably worse prognosis than those occurring elsewhere. Inhibitory effect of tetrandrine on pulmonary metastases in CT26 colorectal adenocarcinoma-bearing BALB/c mice.

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Heparan sulfate proteoglycans made by different basement-membrane-producing tumors have immunological and structural similarities. Just over one-third of those totally work disabled prior to THA were working at 1 or at 4 years after surgery. In vivo incorporation of C14-1-acetate into liver and plasma lipids of postnatally overfed rats.

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Controlled-release particulate cytokine adjuvants for cancer therapy. Here, we tested the hypothesis that the facilitation is mediated via activation of the N-methyl-D-aspartate (NMDA) type of glutamate receptor. Effects of cell growth and apoptosis of preneoplastic Syrian hamster embryo cells by green tea constituent epigallocatechin-3-gallate Barraquer was the first ophthalmic surgeon who consistently took into account modern technology when planning the details of his operating theatre. At 2 to 12 hours, there was reduction or loss of Fc and C3 receptor activity.

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This report underlines the importance of increased and enhanced multidisciplinary research cooperation among health professionals. The availability of homogeneous purified factors and the subsequent availability of monoclonal antibodies against these reagents should allow for the development of rapid quantitative assays for these analytes in diverse biological fluids. leprae, and the other nine showed unique patterns of reactivity by enzyme-linked immunosorbent assay. The PET122 protein is one of three Saccharomyces cerevisiae nuclear gene products required specifically to activate translation of the mitochondrially coded COX3 mRNA. Purified FF-GF was revealed as a single band on SDS-gel electrophoresis and its molecular weight was estimated to be 70 KDa.

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A total of 50 consecutive patients with functional dyspepsia, 50 patients with duodenal ulcer (DU), and 150 healthy blood donor control subjects with no history of peptic ulceration were studied. Biorhythmical prerequisites for organizing the shift work of young workers

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Altogether, the strong linkage disequilibrium and the high degree of cross-reactivity among the allelic products of the SLA complex explain the failure to detect the diversity of our reagents in previous studies. Rabbits were intravenously primed with the antigens human serum albumin (HSA) and bovine gamma globulin (BGG). The examination of the serum lactate dehydrogenase spectrum in patients with benign tumors and chronic inflammatory disease revealed no changes characteristic of malignant neoplasms. One tooth (1.4 percent) in the glass ionomer cement group and three teeth (4.2 percent) in the resin group developed caries. Also in tonsils with adhesions there was a statistically significant higher percentage of EAC rosettes than in tonsils free of adhesions.

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Solvent extraction followed by alumina column chromatography resulted in the isolation of a pharmacologically active material (AP) which was identified to be (25S)-isosolafloridine. The agreement between both approaches, theoretical and simulational, is very good, validating both methods.

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The goal of the project was to understand the PPCPs biological degradation and the extent of sorption to solids. Elastases are unique among the proteases in that they are capable of hydrolyzing the scleroprotein elastin. Adult and pediatric orthopedic clinics at the Health Sciences Centre in Winnipeg. Monitoring of transcutaneous PO2 in the fetus and mother during normal labor.

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DNA origami technique was first introduced in 2006 by Rothemund, it has gained widespread research interest and led to explosive achievements, in which long single-stranded DNA (ssDNA) is folded into a designed nanostructure, in either two dimensions (2D) or three dimensions (3D), with the aid of many shorter staple strands. In vitro steroidogenesis by the nonzoned adrenocortical tissue of the skink, Tiliqua rugosa. The transformed clones contained an estimated 100-500 copies of transfected DNA per nucleus. At the largest volume ratios (R or rd) three different settling regions have been recognised, a region of coalescence, a region of drops moving to the interphase and a region where drops queue at the interphase to coalesce into the large phase.

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Foetal echocardiography enables various pulmonary abnormalities to be detected: pleural effusion, cyst, pulmonary hypoplasia and other disorders. Surgical indications, operative management, and postoperative follow-up are discussed. Epidemiological studies of severe drug hypersensitivities are important to understanding the morbidity and mortality of this heterogeneous group of disorders. Forty obsessive-compulsive ritualizers received nightly placebo or clomipramine up to 225 mgs nocte for 8 months, and received behavioural treatment (exposure to vivo) from weeks 4 to 10.

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Computer simulations are presented using noise-free and Poisson randomized projections. We present a method to measure the spectrally-resolved transmission matrix of a multiply scattering medium, thus allowing for the deterministic spatiospectral control of a broadband light source by means of wavefront shaping. The findings shed light on the dynamics of wake-bubble collisions and the complex behavior induced by multiple laser pulses in plasmas. Nine new dog DLA-DRB1 alleles identified by sequence-based typing. Histological classification of urinary bladder cancers in rats induced by N-butyl-n-(4-hydroxybutyl)nitrosamine.

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Both RAs also stimulated M-CSF production from primary cultures of human bone marrow stromal cells. The results determined that the estimated distance to the THREAT stimulus was significantly underestimated in comparison to the RELIEF stimulus. The mRNA levels for the tumor suppressor gene p53 and the apoptotic genes bax, CASP3 and CASP9 were up-regulated, while the anti-apoptotic gene bcl-2 was down-regulated following nickel ferrite NP exposure. When PGE2 was applied in a recording chamber where the tissue slice was perfused, most of the neurones in the VMH region which responded to PGE2 showed a decrease in their firing rate, while those in the POA region showed an increase in their firing rate, regardless of their thermoresponsiveness.

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The simultaneous occurrence of partial lipodystrophy and retinal pigmentary epithelial and basement membrane changes appears to be a newly recognized syndrome. Three distinct morphological classes of receptors in fish olfactory organs. The sizes of papillary type tumors were smaller and during the follow-up period there was no recurrence in the squamous papillary group.

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We review and critically assess the literature on ETD with respect to syndrome and familial specificity and discuss the quantitative assessment of eye tracking. In addition to providing a conducive environment to a wide range of cellular processes, including transport and signaling, mounting evidence has established active participation of specific lipids in modulating membrane protein function through various mechanisms. Telecare collaborative management increased the proportion of primary care patients with improved chronic musculoskeletal pain.

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There was a significant over-representation of tobacco and alcohol consumers amongst the patients, but a group of elderly females who had never used tobacco or alcohol, yet developed oral cancer, was identified. The pH control and partial feeding of the carbon source at high concentrations were beneficial for growth. A psychometric study assessed the possibility of a preexisting personality configuration in students who became heavy drug users.

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Combined VM-26 and cytosine arabinoside in treatment of refractory childhood lymphocytic leukemia. These results suggest that postprenylation CAAX processing is required for proper localization of farnesylated Ras but not geranygeranylated Rho proteins. Diazetidine-di-N-oxide derivatives have been found capable of the nonenzymatic generation of nitric oxide by a principally new mechanism of nitric oxide splitting at physiological pH values. Semi-quantitative clinical description of oral submucous fibrosis.

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Reliability of the spine adverse events severity system (SAVES) for individuals with traumatic spinal cord injury. The NF-kappaB/RelA family of transcription factors regulates inducible transcription of a large number of genes in response to diverse stimuli. The results were considered positive when the animals presented difficulties in walking and equilibrating. Since February, 1991, following extensive training, a clinical nurse specialist (CNS) has taken on this role and has expanded the service to include a central line insertion service (LIS) throughout the Oxfordshire district. The pilot study GESTALT shows that the concept of interactive knowledge to action has substantially contributed to the sustainability of a physical activity programme in the field of dementia prevention.

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Inactivation of the retinoblastoma susceptibility protein is not sufficient for the transforming function of the conserved region 2-like domain of simian virus 40 large T antigen. The effects of body image and desired weight change on eating disorders were generally found to be greater for women than for men, and their effects on student self-rankings of academic ability, social, and psychological traits were more pervasive for women than for men.

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Output of radiopharmaceutical nuclides of known injected doses from a municipal sewage treatment system. However, no change in the urinary excretion of VMA and ascorbic acid was observed in normal animals at all the doses studied. There was no difference of NK activity in peripheral blood between lung cancer patients and the controls.

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Chromosome analysis by handling techniques of 19 species and sub-species of Cercopithecinae shows an important accumulation of chromosome rearrangements (51). The development of experimental neurogenic gastric ulcers was followed by a reduction in the noradrenaline and cAMP levels in the gastric tissue.

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Therefore rationally designed candidate vaccines should be capable of inducing a cell mediated immunity in addition to a humoral immune response. As removal of the brain renin-angiotensin system lowered blood pressure in one strain and inhibited reflex tachycardia in the other, the divergence could mean that the brain renin-angiotensin system acts differently to keep blood pressure elevated in Sprague-Dawley rats and modulate reflex tachycardia in Fischer 344 rats. A C-terminally-anchored Golgi protein is inserted into the endoplasmic reticulum and then transported to the Golgi apparatus. In a case of rheumatic valve disease atrial sounds could be heard and recorded on the phonocardiogram during atrial flutter at a rate of 260/min and an atrioventricular block of 3:1 and 5:1. Nicotine (0.2 mg/kg subcutaneously) significantly increased amphetamine-induced circling behaviour and tended to inhibit apomorphine-induced circling behaviour.

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The bilateral or unilateral administration of 8-OH-DPAT (20 microg) into other thalamic nuclei, or into sites dorsal to nPf, did not elevate vocalization thresholds. We retrospectively compared the intraoperative locations of labral and cartilage damage of 40 hips during surgical dislocation for cam or pincer type femoroacetabular impingement (Group I) with the locations of femoroacetabular impingement in 15 additional hips using computer simulation (Group II). Considerations for the rapid deployment of vaccines against H7N9 influenza. Surgical treatment of coronary insufficiency produced by cardiac echinococcosis.

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We now show that a 50-kDa protein binds to this region of PSG12, and the resultant complex can be supershifted by a monoclonal antibody to PEA3. The assay is based on two specific reagents: a recombinant protein constituted by a portion of the HIV-1 Gag polyprotein comprising the p17-p24 cleavage site, fused to E.

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To investigate the molecular basis for transcriptional regulation by ethylene we have examined the Chn48 promoter to identify cis-elements and trans-acting factors that are involved in the chitinase gene expression. An improved apparatus for the measurement of oxygen concentration. The myeloma proteins thus separated were then passed through either diethylaminoethyl (DEAE) ion exchange chromatography and recycled in a Sephadex G-200 column, or first through gel filtration and recycled in DEAE. The mutant cells bore T-cell surface markers, maintained their thioguanine resistance in vitro in the presence or absence of selection, and were deficient in hypoxanthine-guanine phosphoribosyltransferase activity.

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In addition, Vmax and RI values of vascular structures were calculated by Doppler spectral evaluation. Accommodation behaviour during prey capture in the Vietnamese leaf turtle ( Geoemyda spengleri).

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Shaping the future of nanomedicine: anisotropy in polymeric nanoparticle design. Eighteen apparently healthy women with normal menstrual cycles were studied during a control cycle and then during a treatment cycle, in which graded doses (2.5, 5.0 and 10 mg/day) of medroxyprogesterone acetate (MPA) were administered orally on cycle days 7 to 10. Proper definition of the other mechanisms of MDR, and how to antagonize them, is an urgent research priority.

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Twenty-five patients were treated with carboplatin, 600 mg/m2, intravenously once every 4 weeks for a total of 4 planned cycles. Experience and accuracy can result in parity of outcomes following one or two stents for left main stem bifurcation disease. Morphometry was performed in corneal flat mounts using lymphatic endothelial hyaluronan receptor-1 (a specific lymphatic endothelial marker), CD31 (a panendothelial marker), and F4/80 (a marker for mononuclear phagocytes). The breakpoint was fully characterized by DNA sequencing and demonstrated that the deletion resulted from Alu-mediated recombination.

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Five of the six foreign bodies and all of the filaments in the six filamentary keratitis cases were removed with minimal damage to the surrounding cornea. Regression of early atherosclerosis in hyperlipidemic hamsters induced by fosinopril and captopril. We questioned whether the selective mineralocorticoid receptor blocker eplerenone improves resistance artery remodeling in hypertensive patients versus the beta-blocker atenolol. When cholic acid and cholesterol are given together, only cysteine sulfinate decarboxylase activity is changed.

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Dynamic drug concentrations in the aqueous phase are monitored both in loading and release experiments. Cells were isolated that were resistant to the ascitic fluid factor(s) stimulating differentiation (D-factor). High affinity interactions with metabotropic 5-HT receptors (2A/C and 1A subtypes) in frog oocytes and expression systems have been reported, but functional in vitro evidence for the modulatory effect is still lacking. This novel approach is directed at analyzing dysfunction in electron transport, ADP phosphorylation and leak respiration to provide insight into potential mechanisms and possible interventions for mitochondrial dysfunction in the immature brain in focal TBI by delineating targets within the electron transport system (ETS).

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In this study, polyclonal and monoclonal antibodies were raised against the purified wild-type recombinant murine 8-oxoG DNA glycosylase (mOGG1) protein and their specificity against the native enzyme and the SDS-denatured mOGG1 polypeptide were characterized. The difference between diffuse and nodular forms of goiter was assessed by scintigraphy.

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A compact twelve-channel photon-counting device based on existing Generation II imaging technology has been developed for use as the image-plane detector of the Dynamics Explorer Fabry-Perot interferometer. Thiopentone and althesin-preferably after diazepam - appeared to suit shorter operations, while propanidid may be useful only for very quick maneuvers. The immunosuppressive strategy investigated is effective and displays a satisfactory safety profile in high immunological risk renal allograft recipients. The dose-dependent interaction of LTAs with purified C1 and C1q was dependent on the negative charges of the phosphate groups of LTA.

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However, the mechanism underlying the creation and narrowing of a membrane neck in the generation of large TCs remains unknown. The prostaglandin E2(PGE2) levels in gingival crevicular fluid (GCF) of 46 normal controls and 90 patients suffering from periodontitis with periodontal pocket of different depth were measured by radioimmunoassay (RIA). The Load Sharing Classification of spinal fractures provides a basis for the choice of operative approaches, but the reliability of this classification system has not been established. When must pulmonary tuberculosis be treated surgically even today?

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The thin layer chromatogram binding assay was used to study the reaction of several natural-monoclonal autoantibodies which recognize sialic acid-dependent antigens of human erythrocytes. Placing workplace wellness in proper context: value beyond money. Interaction of these mAbs with their ligand results in modulation of the mAb-ligand complex from the cell surface.

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Health surveillance is itself a term which straddles occupational and public health medicine. In addition, these cells were able to bind fluid phase C3b, which inhibited any subsequent SEAIgMC1-3b rosette formation. These applications demonstrate the strengths and limitations of meta-analysis, issues that arise in various data realms, how meta-analysis design choices can influence interpretation of results, and how meta-analysis can be used to address bias and heterogeneity. Identifying parental preferences for corticosteroid and inhaled beta-agonist delivery mode in children with acute asthma exacerbations. We develop a semiparametric estimated likelihood method for the proportional hazards model with discrete time data and a binary covariate of interest.

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In both the in vitro and in vivo systems, application of recombinant TNF-alpha alone either to untreated keratinocytes or into normal murine skin did not induce sunburn cells. b) Substances inhibiting the meiotic and postmeiotic phases of spermatogenesis. Compliance to recommended infection control procedures: changes over six years among British Columbia dentists. Donor-derived cells were only detected in the lobe of the thymus in which cells were previously injected and not in the noninjected lobe. In addition, otd is allelic to ocelliless (oc), a mutation that causes the deletion of the ocelli of the adult fly.

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In two children the spinal deformity could be recognized easily on the scout view. Development of a scoring system for predicting the risk of preterm birth in women receiving cervical cerclage. Work roles are considered in order to provide a framework for the analysis of the work of nurses. These results expand our understanding of MUS-101 regulation and show that genetic interactions can be uncovered using screening strategies that rely solely on RNAi. Male sex cells develop in cysts surrounded with a membrane consisting of cells which resemble pinacocytes by their ultrastructure.