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A new shuttle vector, pRH3 (8.7 kb), was constructed for use in Prevotella/Bacteroides host strains. We have used the cyclin binding motif (CBM) present in the tumor suppressor proteins p21(WAF1) and p27(KIP1) as a template to optimize the minimal sequence necessary for CDK2/CA inhibition. Tumor necrosis factor enhances the neutrophil-dependent increase in endothelial permeability. Each of the organs is of key importance for intrauterine and individual development, yet they vary greatly in growth dynamics throughout pregnancy.

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We examined the corneal endothelium of five patients with the clinical specular microscope before and at intervals after combined cataract extraction and intraocular lens implantation. In Cyp1a1mRen2 rats, renin-dependent hypertension synergises with streptozotocin-induced hyperglycaemia to produce a 500-fold increase in albuminuria, glomerulosclerosis and tubulointerstitial fibrosis.

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Limitations could be reduced by applying a record linkage with clinical data. The costs of family contributions to the care of persons with dementia. Metabolic decompensation must be treated aggressively to avoid permanent brain damage. The expressed needs of the people with respect to communication with medical staff both during illness and after a death are presented and are explored in the light of the quest of one of us (D.M., a senior community member) for information about the causes of the deaths of several men of the community. It is suggested that the endogenous release of AII and/or opioids somehow modulate basal rearing activity.

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The result substantiates the view that cigarette smoking has no antibacterial potency so as to reduce plaque formation on tooth surfaces. Pulmonary extravascular water has been measured as lung thermal volume (LTV) in a group of nine burned patients. Studies of the pool of nucleotide precursors, show that the observed variations of orotic acid incorporation into RNA reflect variations in RNA synthesis.

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A 62-year-old man with alcoholic cirrhosis presented with massive gastrointestinal bleeding 4 years after a Warren operation. Stool specimens were cultured selectively for ciprofloxacin-resistant gram-negative bacteria. These results suggest that the cause of loss of the large myelinated fibers may be some disturbance of metabolism in the Schwann cells due to mitochondrial dysfunction.

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Test-retest and interrater consistencies were examined for each of the scales. The implications of a self-disclosure-reference-individual strategy for the study of stigma and for intervention purposes are discussed. These results provide a foundation for the subtype-specific assembly of T3SS sorting platforms and will support further mechanistic analysis and anti-virulence drug design. Carrageenin or IL-8 was injected into a preformed air pouch, and exudate was collected 4 h later for measurement of myeloperoxidase activity.

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The role of neurosis in phylogenetic adaptation, with particular reference to early man. Incubation of the cells for 30 min with either diethylcarbamazine or monensin before fixation permitted detection of glycosaminoglycans and proteoglycan monomers in the middle cisternae, whereas HID staining of the Golgi complex, but not that of secretory vesicles, was abolished. The synaptic membrane D2-protein in amniotic fluid from pregnancies with fetal neural tube defects. Higher doses inhibited A-delta responses but not A-beta responses.

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Influence of surface hydrophilicity of liposomes on their interaction with plasma protein and clearance from the circulation: studies with poly(ethylene glycol)-coated vesicles. Seven adult patients with good ventricular function who underwent myocardial revascularization were studied before and three hours after digoxin (0.5 mg, iv). These alterations were characterized by quantifiable decreases in cell density, cell size and the widths of the layers of posterior neocortex.

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Long-term follow-up after adrenalectomy for primary aldosteronism. Study on the method for determination of analgin using flow injection spectrophotometry Three different semiconductor lasers and four multimode fibers having numerical apertures in the 0.16-0.40 range were used. However, a wide variation in migration indices was observed in both groups of sensitized animals, with some animals showing a significant enhancement of macrophage migration.

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We examined T-cells, B-cells, and natural killer cells of four normal individuals for surface-bound fibronectin (FN) using fluorescence-activated cell sorter analysis and double fluorescence labeling with monoclonal antibodies. The effect of the environmental temperature on the healing of fractures was assessed in vertebrae of tails of young albino mice. Cyclin Es is expressed at approximately 1/10 of the level of full-length cyclin E in several cell lines analysed. Clinical follow-up of metal ceramic crown and bridge restorations made of nonprecious metal alloys Fatty acid interdigitation in stratum corneum model membranes: a neutron diffraction study.

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Patients received a loading dose of rhuMAb HER2 (250 mg i.v.) on day 0, followed by weekly doses of 100 mg i.v. It is suggested that the estrogen plays an important role in the pathogenesis of nasal hypersensitive reactions. Collectively there was improvement in pain (mean 6.7 to 3.5) and diet (mean 2.2 to 3.0) scores with a moderate increase in interincisal distance (mean 21 to 24mm). Toxicity was relatively mild and consisted primarily of leukopenia.

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Echoplanar MR imaging of the liver in patients with focal hepatic lesions: quantitative analysis of images made with various pulse sequences. Although opiate antagonists were able to induce slight and transient withdrawal signs and symptoms, there was, in the group of patients treated with clonidine and naltrexone together, a low percentage of catabolites in urine and an improvement in mood and family relationships. Eosinophilia in primary biliary cirrhosis: regression under therapy with ursodeoxycholic acid Development of a rhythmic musical exercise program for preschool children with clefts of the lip, palate and soft palate at the Wolfgang Rosenthal Clinic in Thallwitz The ester-linked dimer, 3-oxo-5beta-cholan-24-oic acid (cholan-24-oic acid methyl ester)-3-yl ester, (3alpha,5beta), was obtained by condensation of methyl lithocholate with 3-oxo-5beta-cholan-24-oic acid.

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Results of a limited resection for compromised or poor-risk patients with clinical stage I non-small cell carcinoma of the lung. The benefits of the phase-out agreement are questionable because much arsenic will remain in the environment, and the alternatives to wood preservation with CCA are not without environmental consequences. The FT-IR spectra of a polystyrene/methyl ethyl ketone/toluene solution mixture during the solvent evaporation process, to which were added a substantial amount of artificial noise, have been analyzed. The total trunk muscle activity during extension exercises performed semi-seated on a rehabilitation device or from prone lying corresponds with the predetermined dosage using both estimation methods. The distribution of direct interactions in the spatial structures of globular proteins

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Molecular operations of the sodium-calcium exchanger revealed by conformation currents. Low-intensity ultrasound stimulation in distraction osteogenesis in rabbits. Characterization of a heterogeneous camel milk whey non-casein protein.

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We retrospectively considered seven patients treated for metastatic breast cancer with available samples from the primary tumor before any treatment, cryopreserved metastasis removed during progression and concomitant plasmas. Testicular seminoma in a patient with a constitutively activating mutation of the luteinizing hormone/chorionic gonadotropin receptor. Malignant hemispheric infarction: diagnosis and management by hemicraniectomy. Increased excretion of lactic acid may also be caused by bacterial degradation of intestinal mucus. Double congenital fistulae between esophagus and tracheobronchus in the adult.

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All techniques functioned adequately, with no fracture gap exceeding 1 mm. This investigation suggests a new functional role for the acute-phase reactants alpha 2-macroglobulin, alpha 1-antitrypsin, orosomucoid, and C3 in the modulation of PMN migration and also suggests that the chemokinetic activities of these substances are regulated by specific antagonists at various levels. Vagal modulation of the insulin secretory response to KCl loading in nephrectomized dogs. A geographic cluster of 10 cases of pulmonary hemorrhage and hemosiderosis in infants occurred in Cleveland, Ohio, between January 1993 and December 1994. Electrophysiologic identification and preservation of the superior laryngeal nerve during thyroid surgery.

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We prospectively tested the performance of delayed-enhancement magnetic resonance imaging (MRI) with gadolinium-based contrast for the detection of MI in an international, multicenter trial. The analysis clearly demonstrated that only four of the many concerns raised by the stakeholders could make a difference in the decision: health risks, costs, service reliability, and property values. The elrA gene is part of an operon that comprises four other ORFs encoding putative surface proteins of unknown function. In the first part of the study, recognition time was addressed by varying colour, position and highlighting cues in a computer-simulated version of the picking task. Applications of this method to the sequence analyses of egg white lysozyme and salmon beta-melanotropin are also described.

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Thus mobile technology is a feasible tool in improving attendance rates at outpatient clinics and is economically viable. Dyspepsia: update on etiologic mechanisms and current therapies. Combination of nYAP and gankyrin or p-AKT exhibited improved prognostic accuracy for CCA patients. In patients with renal disease a reduced renal vasodilatory but conserved natriuretic response to dopamine is observed.

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Critical care and vitamin D status assessment: what about immunoassays and calculated free 25OH-D? The genome of GR8 was 3.67 Mb in length and encoded 3,713 putative ORFs. Wasting syndrome in AIDS: pathophysiologic mechanisms and therapeutic approaches.

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Further differences were found between brain and bone marrow CFU-s in the congenitally anemic Wf/Wf mice. Intracerebroventricular (i.c.v.) administration of NT produced a dose-dependent antinociceptive effect in the tail pressure test.

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Corticosterone influences 5-HT1A receptor-mediated responses in the rat hippocampus in vitro: activation of the high affinity mineralocorticoid receptor suppresses 5-HT1A receptor-mediated hyperpolarization, while subsequent activation of lower affinity glucocorticoid receptors enhances the effect of 5-HT. This is an essential step if these programs are to be effective in meeting their goal of improving the quality of care offered to mentally retarded persons by foster family care providers.

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Occasional help, concerning the psychical and physical adaptation phase, at the beginning of dialysis treatment. Future control policies should aim to decrease prevalence but also preempt increasing social inequalities in tobacco use. A computer-controlled flexing test for determining the elastic parameters of highly flexible orthodontic wires The regression of an angiocardiographically and electrocardiographically demonstrated anterior-wall aneurysm following percutaneous transluminal angioplasty Basal magnocellular and pontine cholinergic neurons coexpress FGF receptor mRNA.

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This mechanistic role of microparticles and exosomes in mediating vascular dysfunction indicates that they may represent novel pathways in short or long-distance paracrine transcellular signaling in vascular environment. Addition of serotype 5 LPS to highly purified ribosomes did not protect chickens against challenge exposure with serotype 1 P multocida, but produced PHA titers to serotype 5 LPS. The differentially ubiquitinated proteins/enzymes were mainly responsible for protein binding, catalytic activity, and molecular transducer activity. A comparative study on the patency of crimped and noncrimped vascular prostheses, with emphasis on the earliest morphological changes.

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During intracellular metabolism of selenium, oxidation, reduction, methylation, and selenoprotein synthesis processes are involved, as exemplified by detoxification processes that allow yeasts to survive under culture conditions involving the elevated selenium concentrations which were observed. The initial step of intracellular proteins degradation is discussed on the basis of these results. No definite vestibular damage could be found in these 37 patients, including three patients in whom greatly elevated serum concentrations of netilmicin had been measured. Both drugs were administered in the reverse sequence for 2 or 3 weeks. Bacterial adherence to virus-infected cells: a cell culture model of bacterial superinfection.