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Natural killer cell anergy to cytokine stimulants in a subgroup of patients with heart failure: relationship to norepinephrine. Synthesis and anticancer activity of 2-substituted 2,3-dihydro-1,3,2- benzoxazaphosphorin-4-one and its 2-oxide derivatives.

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The EPG technique can be used as a useful tool to give new insights into the functional effects of new chemical compounds and for early detection of low to moderate levels of resistance of sap-feeding insects to insecticides. We performed lung resection together with esophagectomy in 2 patients with advanced thoracic esophageal cancer. Recombination between temperature-sensitive and deletion mutants of reovirus. A short review of the theoretical and practical performance of myelography and computed tomography in the investigation of sciatica is presented.

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Such repeats are generated from overlap of a morpheme (CGCCG/CGGCG), which depending on reading frame and orientation would produce runs of Ala, Gly, or Pro in proteins. Properties of human testis-specific lactate dehydrogenase expressed from Escherichia coli. Results were summarized and analyzed using a standard set of codes.

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Activation of glutamate receptors initiates a long-term modification in neuronal excitability that may represent a parallel, synergistic substrate for learning and memory. Molecular cloning of the complementary DNA predicts that BSF-2 is a protein of relative molecular mass (Mr) 26,000 similar or identical to interferon beta 2, hybridoma plasmacytoma growth factor and hepatocyte stimulating factor. Metabolism of aniline in vivo is stimulated by phenobarbital and 3,4-benzpyrene, and inhibited by SKF 525-A. The visna transcriptional activator Tat: effects on the viral LTR and on cellular genes. Adoptive transfer of experimental autoimmune thyroiditis (EAT) with in vitro activated lymph node cells from thyroglobulin-sensitized guinea pigs: characterization of the cell that transfers EAT.

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The first documented case of primary malignant giant cell tumor of the jawbones is reported. Audiometrical methods can be used objectively for the diagnosis of functional cerebrovascular disorders. There is limited information available from low and middle-income countries regarding the cost of stroke treatment. We conclude that completeness of resection and grade of the lesion are primary determinants of survival. The effect of transfection of the CEA gene on the metastatic behavior of the human colorectal cancer cell line MIP-101.

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Long-term lithium treatment causes serotonin receptor down-regulation via serotonergic presynapses in rat brain. Further study will be performed to investigate whether target of their expression can be used as a novel strategy in clinical control of gastric cancer metastasis. Cytotoxic granules are also not detected in NK cells isolated from animals. Serological typing of a panel of 23 independently derived mouse-human and Chinese hamster-human somatic cell hybrids showed unequivocally that the expression of cell surface antigens A123/A127, M68, and V1 segregates with human chromosome 12.

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The best results were obtained in patients who were referred within 4 months of prostatectomy because of incomplete excision rather than waiting for palpable local recurrence to develop. It is not yet clear if this receptor tyrosine kinase-independent signal utilizes known PDGF second messengers, but these results demonstrate a new arm of the PDGF signal transduction pathway which operates in the absence of, and independently from, autophosphorylation of the receptor on tyrosine. A 60-year-old man developed a widely metastatic spindle cell neoplasm with admixed osteoclast-like giant cells indistinguishable from malignant giant cell tumor of soft parts. Genetic dissection of the Mom5 modifier locus and evaluation of Mom5 candidate genes. One thousand consecutive patients with singleton pregnancy and vaginal delivery in February and March 1993.

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This study investigated whether nonverbal auditory memory representations can be affected by rehearsal strategies. The role of the O and K antigens in determining the resistance of Klebsiella aerogenes to serum killing and phagocytosis. Coagulation factors V and VIII and ceruloplasmin constitute a family of structurally related proteins.

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We used four pancreatic cancer cell lines (Panc1, T3M4, BxPC3, and MIApaca2) to measure cell proliferation and COX-2 mRNA expression after PAR-2 activation. Sucrose density gradient fractions of two of the infectious human sera (peak reverse transcriptase activity at 1.14 g/ml) transmitted NANBH to chimpanzees. 5-ALA has no photoactive properties, but when it is given exogenously, it acts as a precursor of photosensitive porphyrins predominantly in tissues or organisms that are characterized by a high metabolic turnover, such as tumors, macrophages, and bacteria. Not all of these mechanisms appear to be active in every tumor, however. Presenting symptoms, diagnostic tests, diagnoses established, and clinical course were evaluated.

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Oxidation of straight-chain fatty acids in mitochondria involves the complicated interaction between a large variety of different enzymes. Thermal denaturation of DNase I and LDH samples in HSDSC was not reversible upon cooling of thermally denatured proteins (in contrast to lysozyme). The validity of the test compares favorably to the Ishihara, F-2, and the AO-HRR screening plates. These consisted of (a) a modest sustained lymphocytosis, (b) eosinophilia in six (out of nine) patients and (c) a significant rise in IL2-stimulated peripheral blood lymphocyte activated killer (LAK) cell activity in six (out of nine) patients to a mean of 2.0 times pretreatment levels (P less than 0.01).

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Hydroperoxide metabolism in trout gill tissue: effect of glutathione on lipoxygenase products generated from arachidonic acid and docosahexaenoic acid. Transcriptional regulation of the human neuropeptide Y gene by nerve growth factor. Furthermore, we show that the cAMP dependent changes in the expression of cytoskeleton regulators such as doublecortin are restricted to a short time window prior to the establishment of functional neurons. Medical-legal aspects of dental radiology in personal injury cases.

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Assessment of response was made on clinical grounds and by monitoring of immune function (T and B cell numbers, immunoglobulin levels, PHA response and delayed cutaneous reaction to Candida antigen). Pharmacological approaches of fibrin gel architecture modulation and thrombus degradation: its implication in atherogenesis and thromboembolism disease. The RIA using insulin radiolabelled at multiple sites detected insulin antibodies in 17/20 and insulin autoantibodies in 13/20 sera.

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Because this assay can be completed within 30 min of obtaining a blood or urine sample, it should be a valuable tool in clinical drug monitoring and pharmacokinetic studies. We studied all 74,580 children below 18 years of age, belonging to 95 GP practices within the second Dutch national survey of general practice (DNSGP-2), in which GPs registered all physician-patient contacts during the year 2001. Inhibition of matrix metalloproteinase (MMP) and cyclo-oxygenase (COX) decreased PAR2 agonist-induced periodontitis. Endocarditis caused by Rhodotorula successfully treated with 5-fluorocytosine. However, the response in ipsilateral cortex was found to be dependent on an intact projection from nucleus basalis to cortex.

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The methods discussed include fluorometric liquid chromatography, cytotoxicity assays, channel binding assays, and enzyme-immunoassays. Cholesterol and blood glucose screening in public studies by the health office This article outlines the key developments on the hardware side, both in the recent past and in the near future, with a focus on two key issues: energy efficiency and the cost of moving data. We show that, in countries with small populations, limited resources and in absence of surveillance, national mortality statistics and routine hospital data can be combined to adequately model national estimates of acute MI incidence. A fourth subtype of B27 (non-B27W and non-B27K), designated as B27D, was detected by 1D-IEF.

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Localization of short/branched chain acyl-CoA dehydrogenase (ACADSB) to human chromosome 10. The test cells exhibited improved adhesion and therefore improved efficiency as compared to cells treated with the currently used diluted HF. Bleomycin resulted in palmar swelling, erythema, and digital pulp necrosis, which healed secondarily. A specific inhibitor of CatS which is cleared quickly from plasma may produce a transient decrease in plasma CatS activity which is followed by a more prolonged increase in plasma CatS mass which may have implications for the future clinical development of inhibitors of CatS.

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During the 1-year monitoring, a total of 43 Vibrio strains were isolated: 23 Vibrio alginolyticus, 1 Vibrio cholerae, 4 Vibrio vulnificus, and 15 Vibrio parahaemolyticus. It is concluded that the CPT is a cost-effective measure of the attentional deficit commonly found in affected schizophrenia subjects and those at risk for the disorder, and is therefore a potentially valuable screening device for preventive intervention programs. There is little increase in the permeability to carbon in NZB/WF1 mice at the age of 4 weeks, suggesting that the increase in vascular permeability begins between the ages of 4 and 9 weeks. Full-mouth probing pocket depth (PPDs) and percentage bleeding on probing (BOP) scores around teeth and implant(s) were assessed and compared.

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Based on acoustic analysis and morphological characters, the populations from NE Romania are considered to belong to a different subspecies, I. Few attempts have been made to compare bacteremic and non-bacteremic pneumococcal pneumonia, mainly because it is difficult to gain agreement on which cases represent non-bacteremic pneumococcal pneumonia.

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In contrast, we found no evidence for the presence of either known sulfonylurea receptors (SUR1 or SUR2) in the mitochondria. Extracellular interactions of the complexes with anionic glycosaminoglycans (GAGs) may interfere with gene transfer. Antigenic and immunogenic activity of LSP in the crude liver proteins was decreased by the treatment of freezing and thawing, and the recovery of the antigenic activity seemed to correlate with the susceptibility of immunized mice to the induction of liver damage. A randomized controlled trial of mite allergen-impermeable bed covers in adult mite-sensitized asthmatics.

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Hormonal control of apoptosis: the rat prostate gland as a model system. In this study, genomic footprinting analysis has identified a common basis for the deficient response of the hsp70.1 gene to heat shock in four such cell lines, viz., the promoter is inaccessible to transcription factors, including heat shock transcription factor. Our study provides an optimalization of the purging conditions in autologous bone marrow transplantation, by using a low concentration of BSA during ET-18-OCH3 treatment (20 micrograms/ml for 4 h) in serum-free culture medium. Tumour pathology and outcomes were compared in young British patients with breast cancer with and without a family history of breast cancer.

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A novel compound, PS-990, which induces differentiation of neuroblastoma cells, was isolated from the culture broth of a fungus, Acremonium sp. Brain structural changes in schizoaffective disorder, and how far they resemble those seen in schizophrenia and bipolar disorder, have only been studied to a limited extent.

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We have endeavored to circumvent these by developing a pair of transfected cell lines. Femoral percutaneous closure devices can reduce immobilization time, but their safety in the presence of abciximab in respect to hemorrhage has not been clearly determined. Laminins are structurally and functionally major components of the extracellular matrix. It is shown that the most efficient method incorporates a long refractory period of the atrial detection after ventricular depolarization. A new variant case of muscle phosphofructokinase deficiency, coexisting with gastric ulcer, gouty arthritis, and increased hemolysis.

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Electron microscopy what Izzits revisited: an ultrapath VI quiz. Most striking was the accumulation of large amounts of LDV RNA in newly generated germinal centers of lymph nodes and the spleen. C translated from the SP-ORF construct as well as authentic C from infected cells comigrated with the C-plus-signal protein, indicating that the E2 signal was not removed.

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Determination of axon terminal density in the central nervous system. Developmental dental anomalies including unerupted and impacted permanent teeth and associated hyperplastic tooth follicles are seen frequently in MPS patients. The primary aim of this study was to compare magnetic resonance imaging and ultrasound evaluation with intraoperative findings and provide a reliable description of the occurrence of each radiological sign.

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To establish the type and frequency of mutations causing late onset 21-hydroxylase deficiency and associated clinical and biochemical phenotypes and to compare these findings to those from heterozygotes and homozygotes for classical 21-hydroxylase deficiency. Both surgeons and anaesthetists perceived the SSC as a valuable tool in improving intraoperative patient safety and communication among health care professionals, with lesser importance in facilitating teamwork (and eliminating hierarchical categories). 13 cases of hysterectomy carried out to stop bleeding immediately after delivery have been studied. Predicted aqueous and gaseous concentrations of PBDEs were derived from the soil-water and soil-air partitioning models, respectively, and good agreements were obtained between the predicted and previously reported values.

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The female sex hormone system may play a major role in the development of both MCT(P) and MCT(O). The beneficial effect of mannitol on postoperative renal function in children undergoing cardiopulmonary bypass surgery. The demonstration of the trachea and the surrounding tissue and vessels on MR images permitted the evaluation of the cause of trachea, compression and the degree and location of collapse. Dynamic network-based relevance score reveals essential proteins and functional modules in directed differentiation.

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The aim was to select a recommendable dose schedule based on recording of uterine contractility, clinical outcome and measurement of the resulting plasma levels of the two prostaglandin metabolites 15-keto-13, 14-dihydro-PGE2 and 15-keto-13, 14-dihydro-PGE2 alpha by gas-chromatography-mass spectrometry and by radio-immunoassay. The modification of LDL resulting from exposure to glucose alters macrophage ceroid accumulation, a process which occurs in the human atherosclerotic plaque. To promote a comprehensive study of orphan pulmonary diseases, we established a network of pulmonologists, allowing us to collect and study several series of patients. TNF alpha levels are increased during bone marrow transplantation conditioning in patients who develop acute GVHD. Therefore, in the present in vitro work we intend to compare the effect of these different treatment regimens on breast cancer risk.

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The two groups differed much less with reference to items that assessed knowledge of matters pertaining to confidentiality, as well as information afforded their clients. These algorithms can achieve registration with an accuracy equivalent to that of the conventional fast Fourier transform upsampling approach in a small fraction of the computation time and with greatly reduced memory requirements. The aim of present study was to assess the maternal serum levels and clinical significance of interleukin-18 (IL-18) in pregnancies complicated by preeclampsia and/or intrauterine growth restriction (IUGR). The surface is integrated to calculate time-dependent volume changes during respiration.

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Effects of effort on attributed intent and perceived aggressiveness. The case is important because this type of stress fracture has previously been considered to be safe from risk of complete fracture. These results suggest that the phosphorylation level of pRb could be associated with the cell differentiation process in human colonic epithelium and as a consequence in its neoplastic development. Chi2 Tests compared HIV seroprevalence across groups according to demographic characteristics and toxicology findings. A 105,000 X g supernatant of tissue homogenate from which endogenous unbound steroid was removed by dextran-coated charcoal was used for the cytosol.

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Additionally, recent evidence suggests that autophagy can selectively eliminate damaged mitochondria. On the other hand, no differences in the basal levels of synaptic proteins implicated in synaptic plasticity (total ERK, synapsin, growth-associated protein-43, and neurogranin) were detected. The high rate of infection with hepatitis B virus in certain defined populations in industralized countries and among the general population in many non-industrialized countries stresses the need for hepatitis B vaccines. Methods derived from observational epidemiology, including multiple regression, logistic regression and proportional hazards regression, are appropriate here.

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The author describes the development, implementation, and structure of the Los Angeles course. Clinical aspects of so-called fibro-cemento-osseous lesions of the jaw

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Environmental noise pollution increases the risk for hearing loss, stress, sleep disruption, annoyance, and cardiovascular disease and has other adverse health impacts. The findings suggest that food consumption affects general arousal, rather than specific cognitive EEG or ERP factors and are discussed with respect to previous EEG-ERP findings on food intake. We used data from a prospective longitudinal study of a complete birth cohort born in New Zealand.

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Characterisation of the single copy trefoil peptides intestinal trefoil factor and pS2 and their ability to form covalent dimers. In all cases, the non-adherent or T-enriched cells adoptively transferred suppression to HSA, however, the suppressive effects of the non-adherent cells were never as great as those of the unpassed population of SpM cells.

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Pigmented melanocytes isolated in culture from the epidermis of guinea pig ears were used to study the unscheduled DNA synthesis (UDS) induced by ultraviolet (UV) irradiation at 254 nm. Optical emission from AuNCs is not proportional to Cerenkov radiation, indicating that the energy transfer between the radionuclide and AuNC is only partially mediated by Cerenkov photons. By trypsin digestion of intact cells and analysis of released enzyme activities into the medium new information on isozyme expression of amino acid naphthylamidase in the granulocyte-monocyte lineages could be achieved. Total RNA was isolated from sections of the inner and outer cortex, inner and outer medulla, papillary tips, and renal pelvis and from glomeruli isolated by sieving.

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Observations on the accuracy of photometric techniques used to measure some in vivo microvascular blood flow parameters. High plasma concentrations of osteopontin in patients with interstitial pneumonia. A linker in the AX9m mutant of Fujinami avian sarcoma virus (FSV) introduces a dipeptide insertion into the SH2 domain of the P130gag-fps PTK, which abolishes its ability to transform Rat-2 cells.

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Results indicated significantly higher rates of CD in parents of schizophrenic and schizotypal children than in parents of children with major depression and dysthymic disorders. A case report of pheochromocytoma showing AMI like ECG changes and transient apical defect on 201-T1 myocardial SPECT

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Two foamy virus infections are demonstrated in human contacts of the African green monkey colony, with the animal harbouring the isolate. Additional safeguards are recommended for aggregate fruits with respect to the risk from protozoa.

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In vitro, Vgamma9Vdelta2 T cells exhibit strong cytolytic activity against Brucella-infected cells and are able to impair intracellular growth of Brucella suis in autologous macrophages. MELD accurately predicts mortality in patients with alcoholic hepatitis. We report the successful treatment of such a complication in an adolescent with homozygous beta-thalassemia by surgery followed by repeated blood transfusions aimed at maintaining hematocrit at normal levels.

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The findings from the workers with heavy exposure to lead provided some evidence to support the hypothesis of an association between stomach and lung cancer and exposure to lead. Human protein S functioned as a cofactor to human protein Ca, but not to bovine protein Ca, whereas bovine protein S demonstrated very little species specificity and functioned as a cofactor both with human and bovine protein Ca. The level of the stapedius reflex showed an increase of 5 dB in one of these three positions.